Safety and immunogenicity of Sinovac's prototype pandemic influenza H5N1 vaccines: a review on clinical trials.

abstract：:A myriad of risk factors have been linked to an increase in the severity of the pandemic H1N1 2009 influenza A virus [A(H1N1)pdm09] including pregnancy and obesity where death rates can be elevated as compared to the general population. The goal of this review is to provide an overview of the influence of pregnancy an...

journal_title：Influenza and other respiratory viruses

authors： Karlsson EA,Marcelin G,Webby RJ,Schultz-Cherry S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Wild birds are the natural hosts for influenza A viruses (IAVs) and provide a niche for the maintenance of this virus. OBJECTIVES:This study was undertaken to analyze nucleotide sequences of the matrix (M) gene of AIVs isolated from wild birds and live bird markets (LBMs) to index the changes occurring in t...

journal_title：Influenza and other respiratory viruses

authors： Chander Y,Jindal N,Sreevatsan S,Stallknecht DE,Goyal SM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:It has been suggested that live attenuated influenza vaccine (LAIV) may be less effective in older individuals because of prior wild-type influenza infections. LAIV is currently approved in the United States, South Korea and Hong Kong for individuals 2-49 years of age. OBJECTIVE:To examine data from previou...

journal_title：Influenza and other respiratory viruses

authors： Belshe RB,Toback SL,Yi T,Ambrose CS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:We determined influenza A(H1N1)pdm09 antibody levels before and after the first wave of the pandemic in an urban community in Dhaka, Bangladesh. METHODS:We identified a cohort of households by stratified random sampling. We collected baseline serum specimens during July-August 2009, just prior to the initia...

journal_title：Influenza and other respiratory viruses

authors： Nasreen S,Rahman M,Hancock K,Katz JM,Goswami D,Sturm-Ramirez K,Holiday C,Jefferson S,Branch A,Wang D,Veguilla V,Widdowson MA,Fry AM,Brooks WA

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Equine influenza (EI) is a highly contagious respiratory disease of horses. OBJECTIVES:The aim of this study was to evaluate two rapid antigen detection kits (Directigen or DFA, and Espline) and a commercial ELISA for the detection of EI nucleoprotein in nasal swabs. METHOD:Nasal swab samples from naturall...

journal_title：Influenza and other respiratory viruses

authors： Galvin P,Gildea S,Nelly M,Quinlivan M,Arkins S,Walsh C,Cullinane A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Guillain-Barre syndrome (GBS) is a rare autoimmune disease characterized by acute, progressive peripheral neuropathy and is commonly associated with the presence of antiganglioside antibodies. Previously, influenza vaccination was linked with the increased incidence of GBS; however, whether antiganglioside a...

journal_title：Influenza and other respiratory viruses

authors： Wang DJ,Boltz DA,McElhaney J,McCullers JA,Webby RJ,Webster RG

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...

journal_title：Influenza and other respiratory viruses

authors： van Essen GA,Beran J,Devaster JM,Durand C,Duval X,Esen M,Falsey AR,Feldman G,Gervais P,Innis BL,Kovac M,Launay O,Leroux-Roels G,McElhaney JE,McNeil S,Oujaa M,Richardus JH,Ruiz-Palacios G,Osborne RH,Oostvogels L

更新日期：2014-07-01 00:00:00

abstract：:A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm0...

journal_title：Influenza and other respiratory viruses

authors： Komissarov A,Fadeev A,Sergeeva M,Petrov S,Sintsova K,Egorova A,Pisareva M,Buzitskaya Z,Musaeva T,Danilenko D,Konovalova N,Petrova P,Stolyarov K,Smorodintseva E,Burtseva E,Krasnoslobodtsev K,Kirillova E,Karpova L,Eropk

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is an important cause of medically attended acute respiratory illnesses in older adults but awareness of the relevance of RSV in older people remains lower than that of influenza, which exhibits similar clinical characteristics to those of RSV. OBJECTIVES:This study was per...

journal_title：Influenza and other respiratory viruses

authors： Zhang Y,Wang Y,Zhao J,Xiong Z,Fan Y,Zhang W,Zou X,Wang C,Han J,Li B,Lu B,Cao B,CAP-China Network.

更新日期：2020-09-01 00:00:00

abstract：:Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for ...

journal_title：Influenza and other respiratory viruses

authors： Imamura T,Suzuki A,Lupisan S,Kamigaki T,Okamoto M,Roy CN,Olveda R,Oshitani H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Despite the use of vaccines, low-pathogenic (LP) H5N2 influenza viruses have continued to circulate and evolve in chickens in Mexico since 1993, giving rise to multiple genetic variants. Antigenic drift is partially responsible for the failure to control H5N2 influenza by vaccination; the contribution of mat...

journal_title：Influenza and other respiratory viruses

authors： Forrest HL,Garcia A,Danner A,Seiler JP,Friedman K,Webster RG,Jones JC

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Influenza-associated myositis (IAM), characterized by severe lower-extremity myalgia and reluctance to walk, is a complication of influenza among children. We investigated IAM in Nebraska during six influenza seasons, 2001-2007. METHODS:During 2006-2007, we requested reports of severe influenza illness among...

journal_title：Influenza and other respiratory viruses

authors： Buss BF,Shinde VM,Safranek TJ,Uyeki TM

更新日期：2009-11-01 00:00:00

abstract：:Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following treatment. Here, we d...

journal_title：Influenza and other respiratory viruses

authors： Koszalka P,Farrukee R,Mifsud E,Vijaykrishna D,Hurt AC

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Lower respiratory tract illness is a major cause of morbidity and mortality in children worldwide, however, information about the epidemiological and clinical characteristics of LRTIs caused by HMPV and HBoV in China is limited. OBJECTIVES:Human bocavirus (HBoV) and human metapneumovirus (HMPV) are two impo...

journal_title：Influenza and other respiratory viruses

authors： Zhou JY,Peng Y,Peng XY,Gao HC,Sun YP,Xie LY,Zhong LL,Duan ZJ,Xie ZP,Cao YD

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Respiratory tract infections are a major cause of outpatient visits, yet only a portion is tested to determine the etiologic organism. Multiplex reverse transcriptase polymerase chain reaction (MRT-PCR) assays for detection of multiple viruses are being used increasingly in clinical settings. METHODS:During...

journal_title：Influenza and other respiratory viruses

authors： Zimmerman RK,Rinaldo CR,Nowalk MP,Gk B,Thompson MG,Moehling KK,Bullotta A,Wisniewski S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Several studies have demonstrated the role of meteorological parameters in the seasonality of influenza viruses in tropical and subtropical regions, most importantly temperature, humidity, and rainfall. OBJECTIVES:This study aimed to describe the influence of meteorological parameters in the seasonality of ...

journal_title：Influenza and other respiratory viruses

authors： Munshili Njifon HL,Monamele CG,Kengne Nde C,Vernet MA,Bouba G,Tchatchouang S,Njankouo MR,Tapondjou R,Deweerdt L,Mbacham W,Njouom R

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the upper respiratory tract may stop influenza transmission. It is therefore important to develop effective intranas...

journal_title：Influenza and other respiratory viruses

authors： Svindland SC,Pedersen GK,Pathirana RD,Bredholt G,Nøstbakken JK,Jul-Larsen Å,Guzmán CA,Montomoli E,Lapini G,Piccirella S,Jabbal-Gill I,Hinchcliffe M,Cox RJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections are a leading cause of morbidity and mortality worldwide. Starting in 2009, pandemic influenza A(H1N1) 2009 virus has become one of the leading respiratory pathogens worldwide. However, the overall impact of this virus as a cause of mortality has not been clearly defined. OBJECT...

journal_title：Influenza and other respiratory viruses

authors： Comas-García A,García-Sepúlveda CA,Méndez-de Lira JJ,Aranda-Romo S,Hernández-Salinas AE,Noyola DE

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Estimating influenza incidence in outpatient settings is challenging. We used outpatient healthcare practice populations as a proxy to estimate community incidence of influenza-like illness (ILI) and laboratory-confirmed influenza-associated ILI. METHODS:From October 2009 to July 2010, 38 outpatient practic...

journal_title：Influenza and other respiratory viruses

authors： Fowlkes A,Dasgupta S,Chao E,Lemmings J,Goodin K,Harris M,Martin K,Feist M,Wu W,Boulton R,Temte J,Brammer L,Finelli L

更新日期：2013-09-01 00:00:00

abstract：:Antiviral drugs continue to be an important option for the treatment of influenza disease and will likely be the only option during the early phases of pandemic. However, the limited number of drug classes licensed for treatment of influenza raises several issues, particularly in the face of drug resistance. Two class...

journal_title：Influenza and other respiratory viruses

authors： Wathen MW,Barro M,Bright RA

更新日期：2013-01-01 00:00:00

abstract：:Influenza antiviral drugs are important for the control of influenza, most specifically for the treatment of influenza patients with severe disease following infection with a seasonal influenza virus, a newly emerging influenza strain, or in the event of a pandemic. Many influenza antivirals that are currently under i...

journal_title：Influenza and other respiratory viruses

authors： Koszalka P,Tilmanis D,Hurt AC

更新日期：2017-05-01 00:00:00

abstract：:The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence...

journal_title：Influenza and other respiratory viruses

authors： Smith LE,D'Antoni D,Jain V,Pearce JM,Weinman J,Rubin GJ

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To preliminary preview the molecular character and its possible clinical correlation of RSV subgroups in Thailand. DESIGN:Cross-sectional analytic design. SETTING:Admitted acute lower respiratory tract infection patients of King Chulalongkorn Memorial Hospital, Bangkok, during Jun-Dec, 2007 were recruited....

journal_title：Influenza and other respiratory viruses

authors： Boonyasuppayakorn S,Kowitdamrong E,Bhattarakosol P

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to investigate the rate of transmission of respiratory viral infections to children visiting the emergency room of a large pediatric hospital during winter. A total of 615 children were prospectively studied. Twenty-two (3·6%) children developed at least one symptom compatible with a respirat...

journal_title：Influenza and other respiratory viruses

authors： Maltezou HC,Mougkou K,Asimaki H,Koniaraki K,Katerelos P,Giannaki M,Theodoridou M

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS:Twenty-six countries in the Southern (n = 5) and Northern (n = 7...

journal_title：Influenza and other respiratory viruses

authors： Caini S,Huang QS,Ciblak MA,Kusznierz G,Owen R,Wangchuk S,Henriques CM,Njouom R,Fasce RA,Yu H,Feng L,Zambon M,Clara AW,Kosasih H,Puzelli S,Kadjo HA,Emukule G,Heraud JM,Ang LW,Venter M,Mironenko A,Brammer L,Mai

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sial...

journal_title：Influenza and other respiratory viruses

authors： Sandbulte MR,Gao J,Straight TM,Eichelberger MC

更新日期：2009-09-01 00:00:00

abstract：:We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Archer C,McRoberts J,Kulik J,Thurston T,Lephart P,Kaye KS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Reviews of the global response to the 2009 pandemic of influenza A/H1N1 affirmed the importance of assessment of preparedness and response capabilities. DESIGN:The U. S. Centers for Disease Control and Prevention (CDC) and partners developed the National Inventory of Core Capabilities for Pandemic Influenza...

journal_title：Influenza and other respiratory viruses

authors： MacDonald G,Moen AC,St Louis ME

更新日期：2014-03-01 00:00:00

abstract：:As the most important viral cause of severe respiratory disease in infants and increasing recognition as important in the elderly and immunocompromised, respiratory syncytial virus (RSV) is responsible for a massive health burden worldwide. Prophylactic antibodies were successfully developed against RSV. However, thei...

journal_title：Influenza and other respiratory viruses

authors： Broadbent L,Groves H,Shields MD,Power UF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. OBJECTIVES:To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. METHODS:We examined 1915...

journal_title：Influenza and other respiratory viruses

authors： Yang W,Petkova E,Shaman J

更新日期：2014-03-01 00:00:00