Abstract:
BACKGROUND:Since 2009, Thailand has recommended influenza vaccine for children aged 6 months through 2 years, but no estimates of influenza vaccine coverage or effectiveness are available for this target group. METHODS:During August 2011-May 2013, high-risk and healthy children aged ≤36 months were enrolled in a 2-year prospective cohort study. Parents were contacted weekly about acute respiratory illness (ARI) in their child. Ill children had combined nasal and throat swabs tested for influenza viruses by real-time reverse transcription-polymerase chain reaction. Influenza vaccination status was verified with vaccination cards. The Cox proportional hazards approach was used to estimate hazard ratios. Vaccine effectiveness (VE) was estimated as 100% x (1-hazard ratio). RESULTS:During 2011-2013, 968 children were enrolled (median age, 10·3 months); 948 (97·9%) had a vaccination record and were included. Of these, 394 (41·6%) had ≥1 medical conditions. Vaccination coverage for the 2011-2012 and 2012-2013 seasons was 29·3% (93/317) and 30·0% (197/656), respectively. In 2011-2012, there were 213 ARI episodes, of which 10 (4·6%) were influenza positive (2·3 per 1000 vaccinated and 3·8 per 1000 unvaccinated child-weeks). The VE was 55% (95% confidence interval [CI], -72, 88). In 2012-2013, there were 846 ARIs, of which 52 (6·2%) were influenza positive (1·8 per 1000 vaccinated and 4·5 per 1000 unvaccinated child-weeks). The VE was 64% (CI, 13%, 85%). CONCLUSION:Influenza vaccination coverage among young children in Thailand was low, although vaccination was moderately effective. Continued efforts are needed to increase influenza vaccination coverage and evaluate VE among young children in Thailand.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Kittikraisak W,Suntarattiwong P,Levy J,Fernandez S,Dawood FS,Olsen SJ,Chotpitayasunondh Tdoi
10.1111/irv.12302subject
Has Abstractpub_date
2015-03-01 00:00:00pages
85-93issue
2eissn
1750-2640issn
1750-2659journal_volume
9pub_type
杂志文章abstract::In this report, we describe the occurrence of two novel swine influenza viruses (SIVs) in pigs in Argentina. These viruses are the result of two independent reassortment events between the H1N1 pandemic influenza virus (H1N1pdm) and human-like SIVs, showing the constant evolution of influenza viruses at the human-swin...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00246.x
更新日期:2011-11-01 00:00:00
abstract:CONTEXT:Preventing nosocomial transmission of influenza is essential to reduce the morbidity and mortality associated with this infection. In October 2009, an outbreak of the 2009 influenza A (H1N1) virus occurred in a hematology ward of a children's hospital over a 21-day period and involved two patients and four heal...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00322.x
更新日期:2012-09-01 00:00:00
abstract::Progress in the development of antivirals for non-influenza respiratory viruses has been slow with the result that many unmet medical needs and few approved agents currently exist. This commentary selectively reviews examples of where specific agents have provided promising clinical benefits in selected target populat...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/irv.12173
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The influenza virus is reportedly associated with 3-5 million cases of severe illness and 250 000-500 000 deaths annually worldwide. OBJECTIVES:We investigated the variation of influenza A virus in Korea and examined the association with death. METHODS:A total of 13 620 cases were enrolled in the Hospital-...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12549
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:The annual differences in the seasonal influenza vaccine and the circulating strains make it necessary to assess influenza vaccine effectiveness (VE) yearly. We assessed the effectiveness of the trivalent inactivated influenza vaccine for the 2010-2011 and 2011-2012 influenza seasons among children in Guangz...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12157
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Influenza and other respiratory infections cause excess winter morbidity in children. This study assessed the economic impact of influenza-like illness (ILI) on families with children attending childcare using a societal perspective. METHODS:We conducted a prospective cohort study in 90 childcare centres an...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12138
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:We determined influenza A(H1N1)pdm09 antibody levels before and after the first wave of the pandemic in an urban community in Dhaka, Bangladesh. METHODS:We identified a cohort of households by stratified random sampling. We collected baseline serum specimens during July-August 2009, just prior to the initia...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12462
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:We aimed to examine the efficacy of medical masks and respirators in protecting against respiratory infections using pooled data from two homogenous randomised control clinical trials (RCTs). METHODS:The data collected on 3591 subjects in two similar RCTs conducted in Beijing, China, which examined the same ...
journal_title:Influenza and other respiratory viruses
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/irv.12474
更新日期:2017-11-01 00:00:00
abstract::We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12115
更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12530
更新日期:2018-05-01 00:00:00
abstract::Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following treatment. Here, we d...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12725
更新日期:2020-07-01 00:00:00
abstract::Systematic reviews and meta-analyses confirm that influenza vaccination reduces the risk of influenza illness by between about 40% and 60% in seasons when circulating influenza stains are well matched to vaccine strains. Influenza vaccine effectiveness (IVE) estimates, however, are often discordant and a source of con...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/irv.12786
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Respiratory protective devices are critical in protecting against infection in healthcare workers at high risk of novel 2019 coronavirus disease (COVID-19); however, recommendations are conflicting and epidemiological data on their relative effectiveness against COVID-19 are limited. PURPOSE:To compare medi...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,meta分析
doi:10.1111/irv.12745
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:During April-July 2009, U.S. hospitalization rates for 2009 pandemic influenza A (H1N1) virus (H1N1pdm09) infection were estimated at 4·5/100 000 persons. We describe rates and risk factors for H1N1pdm09 infection among American Indians (AIs) in four isolated southwestern U.S. communities served by the India...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12123
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sial...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2009.00094.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Community-based studies of influenza and other respiratory viruses (eg, SARS-CoV-2) require laboratory confirmation of infection. During the current COVID-19 pandemic, social distancing guidelines require alternative data collection in order to protect both research staff and participants. Home-collected res...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12822
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Data about influenza mortality burden in northern China are limited. This study estimated mortality burden in Beijing associated with seasonal influenza from 2007 to 2013 and the 2009 H1N1 pandemic. METHODS:We estimated influenza-associated excess mortality by fitting a negative binomial model using weekly ...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12515
更新日期:2018-01-01 00:00:00
abstract::Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for ...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12206
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00377.x
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
doi:10.1111/irv.12245
更新日期:2014-07-01 00:00:00
abstract::The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the imm...
journal_title:Influenza and other respiratory viruses
pub_type:
doi:10.1111/j.1750-2659.2011.00242.x
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:The Northern Territory (NT) of Australia has a mix of climates, sparsely distributed population and a large proportion of the populace are Indigenous Australians, and influenza is known to have a disproportionate impact upon this group. Understanding the epidemiology of influenza in this region would inform ...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12757
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Longitudinal data are limited about the circulating strains of influenza viruses and their public health impact in Indonesia. We conducted influenza surveillance among outpatients and hospitalized patients with influenza-like illness (ILI) across the Indonesian archipelago from 2003 through 2007. METHODOLOG...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00403.x
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:The Yangtze river delta in eastern China, centered on Shanghai, is one of the most populated regions of the world with more than 100 million residents. We examined the impact of influenza on excess mortality in Yancheng, a prefecture-level city with 8.2 million population located 250 km north of Shanghai, ...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12487
更新日期:2018-01-01 00:00:00
abstract:AIM:To determine factors associated with severe hospitalized Respiratory syncytial virus (RSV)-associated LRTI and to describe management in tertiary care center. METHODS:Retrospective medical record review was conducted among children under 5 years old hospitalized with RSV-associated LRTI at King Chulalongkorn Memor...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12793
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Modern molecular techniques reveal new information on the role of respiratory viruses in community-acquired pneumonia. In this study, we tried to determine the prevalence of respiratory viruses and bacteria in patients with community-acquired pneumonia who were admitted to the hospital. METHODS:Between Apri...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00425.x
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:A population-based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy. OBJECTIVES:We studied maternal A(H1N1)pdm09-specific hemagglutination inhibition (HI)-titer levels and waning in women with influenza-...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12623
更新日期:2019-03-01 00:00:00
abstract::The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/irv.12406
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Respiratory tract infections are a major cause of outpatient visits, yet only a portion is tested to determine the etiologic organism. Multiplex reverse transcriptase polymerase chain reaction (MRT-PCR) assays for detection of multiple viruses are being used increasingly in clinical settings. METHODS:During...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12247
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. To date, such estimates have required extensive surveys of target populations. Here, we propose a method for estimating the intrafamily SAR and SI fro...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12321
更新日期:2015-07-01 00:00:00