Inactivated pandemic 2009 H1N1 influenza A virus human vaccines have different efficacy after homologous challenge in the ferret model.

abstract：:We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Archer C,McRoberts J,Kulik J,Thurston T,Lephart P,Kaye KS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sial...

journal_title：Influenza and other respiratory viruses

authors： Sandbulte MR,Gao J,Straight TM,Eichelberger MC

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Since 2009, Thailand has recommended influenza vaccine for children aged 6 months through 2 years, but no estimates of influenza vaccine coverage or effectiveness are available for this target group. METHODS:During August 2011-May 2013, high-risk and healthy children aged ≤36 months were enrolled in a 2-yea...

journal_title：Influenza and other respiratory viruses

authors： Kittikraisak W,Suntarattiwong P,Levy J,Fernandez S,Dawood FS,Olsen SJ,Chotpitayasunondh T

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:At the onset of the pandemic H1N1/09 influenza A outbreak in Australia, health authorities devised official clinical case definitions to guide testing and access to antiviral therapy. OBJECTIVES:To assess the diagnostic accuracy of these case definitions and to attempt to improve on them using a scoring sys...

journal_title：Influenza and other respiratory viruses

authors： Mahony AA,Cheng AC,Olsen KL,Aboltins CA,Black JF,Johnson PD,Lindsay Grayson M,Torresi J

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:Preventing nosocomial transmission of influenza is essential to reduce the morbidity and mortality associated with this infection. In October 2009, an outbreak of the 2009 influenza A (H1N1) virus occurred in a hematology ward of a children's hospital over a 21-day period and involved two patients and four heal...

journal_title：Influenza and other respiratory viruses

authors： Bearden A,Friedrich TC,Goldberg TL,Byrne B,Spiegel C,Schult P,Safdar N

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Influenza A(H3N2), A(H1N1)pdm09 and B viruses co-circulated in Europe in 2017-18, predominated by influenza B. WHO-recommended, trivalent vaccine components were lineage-mismatched for B. The I-MOVE hospital network measured 2017-18 seasonal influenza vaccine effectiveness (IVE) against influenza A(H3N2) and...

journal_title：Influenza and other respiratory viruses

authors： Rose AMC,Kissling E,Gherasim A,Casado I,Bella A,Launay O,Lazăr M,Marbus S,Kuliese M,Syrjänen R,Machado A,Kurečić Filipović S,Larrauri A,Castilla J,Alfonsi V,Galtier F,Ivanciuc A,Meijer A,Mickiene A,Ikonen N,Gómez

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Influenza and other respiratory infections cause excess winter morbidity in children. This study assessed the economic impact of influenza-like illness (ILI) on families with children attending childcare using a societal perspective. METHODS:We conducted a prospective cohort study in 90 childcare centres an...

journal_title：Influenza and other respiratory viruses

authors： Yin JK,Salkeld G,Lambert SB,Dierig A,Heron L,Leask J,Yui Kwan Chow M,Booy R

更新日期：2013-11-01 00:00:00

abstract：:A myriad of risk factors have been linked to an increase in the severity of the pandemic H1N1 2009 influenza A virus [A(H1N1)pdm09] including pregnancy and obesity where death rates can be elevated as compared to the general population. The goal of this review is to provide an overview of the influence of pregnancy an...

journal_title：Influenza and other respiratory viruses

authors： Karlsson EA,Marcelin G,Webby RJ,Schultz-Cherry S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Influenza vaccine coverage rates among healthcare workers (HCWs) in acute care facilities in Canada remain below national targets. OBJECTIVE:To determine factors associated with influenza vaccine uptake among HCWs. METHODS:This secondary analysis of a prospective cohort study included HCWs aged 18-69 years...

journal_title：Influenza and other respiratory viruses

authors： Hussain H,McGeer A,McNeil S,Katz K,Loeb M,Simor A,Powis J,Langley J,Muller M,Canadian Health Care Worker Study Group.,Coleman BL

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Despite the use of vaccines, low-pathogenic (LP) H5N2 influenza viruses have continued to circulate and evolve in chickens in Mexico since 1993, giving rise to multiple genetic variants. Antigenic drift is partially responsible for the failure to control H5N2 influenza by vaccination; the contribution of mat...

journal_title：Influenza and other respiratory viruses

authors： Forrest HL,Garcia A,Danner A,Seiler JP,Friedman K,Webster RG,Jones JC

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Wild birds are the natural hosts for influenza A viruses (IAVs) and provide a niche for the maintenance of this virus. OBJECTIVES:This study was undertaken to analyze nucleotide sequences of the matrix (M) gene of AIVs isolated from wild birds and live bird markets (LBMs) to index the changes occurring in t...

journal_title：Influenza and other respiratory viruses

authors： Chander Y,Jindal N,Sreevatsan S,Stallknecht DE,Goyal SM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:It appears inter-seasonal influenza notifications have been increasing in summer months in Australia. This study aims to determine changes in inter-seasonal influenza activity in Australia over time. METHODS:Routine influenza surveillance data and hospitalisations data were analysed to study the epidemiolog...

journal_title：Influenza and other respiratory viruses

authors： Moa AM,Adam DC,MacIntyre CR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:A point-of-care rapid test (POCRT) may help early and targeted use of antiviral drugs for the management of influenza A infection. OBJECTIVE:(i) To determine whether antiviral treatment based on a POCRT for influenza A is cost-effective and, (ii) to determine the thresholds of key test parameters (sensitivi...

journal_title：Influenza and other respiratory viruses

authors： Nshimyumukiza L,Douville X,Fournier D,Duplantie J,Daher RK,Charlebois I,Longtin J,Papenburg J,Guay M,Boissinot M,Bergeron MG,Boudreau D,Gagné C,Rousseau F,Reinharz D

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:The goal of this double-blind, randomized, controlled clinical trial was to assess the safety and immunogenicity of two different doses of a monovalent split-virion 2009 pandemic influenza A/H1N1 vaccine without adjuvant in Chinese infants aged 6-35 months. DESIGN AND SETTING  Subjects were randomly assigned...

journal_title：Influenza and other respiratory viruses

authors： Li YP,Li W,Liang XF,Liu Y,Huang XC,Li CG,Li RC,Wang JZ,Wang HQ,Yin WD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...

journal_title：Influenza and other respiratory viruses

authors： Mamelund SE

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...

journal_title：Influenza and other respiratory viruses

authors： Coleman LA,Waring SC,Irving SA,Vandermause M,Shay DK,Belongia EA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Lower respiratory tract illness is a major cause of morbidity and mortality in children worldwide, however, information about the epidemiological and clinical characteristics of LRTIs caused by HMPV and HBoV in China is limited. OBJECTIVES:Human bocavirus (HBoV) and human metapneumovirus (HMPV) are two impo...

journal_title：Influenza and other respiratory viruses

authors： Zhou JY,Peng Y,Peng XY,Gao HC,Sun YP,Xie LY,Zhong LL,Duan ZJ,Xie ZP,Cao YD

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is an important cause of medically attended acute respiratory illnesses in older adults but awareness of the relevance of RSV in older people remains lower than that of influenza, which exhibits similar clinical characteristics to those of RSV. OBJECTIVES:This study was per...

journal_title：Influenza and other respiratory viruses

authors： Zhang Y,Wang Y,Zhao J,Xiong Z,Fan Y,Zhang W,Zou X,Wang C,Han J,Li B,Lu B,Cao B,CAP-China Network.

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:This study evaluated the diagnostic value of measuring the levels of procalcitonin (PCT) and C-reactive protein (CRP) to differentiate children co-infected with H1N1 influenza and bacteria from children infected with H1N1 influenza alone. METHODS:Consecutive patients (children aged < 5 years) with laboratory...

journal_title：Influenza and other respiratory viruses

authors： Li Z,He L,Li S,He W,Zha C,Ou W,Hou Q,Wang W,Sun X,Liang H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:We aimed to examine the efficacy of medical masks and respirators in protecting against respiratory infections using pooled data from two homogenous randomised control clinical trials (RCTs). METHODS:The data collected on 3591 subjects in two similar RCTs conducted in Beijing, China, which examined the same ...

journal_title：Influenza and other respiratory viruses

authors： MacIntyre CR,Chughtai AA,Rahman B,Peng Y,Zhang Y,Seale H,Wang X,Wang Q

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To estimate, using Bayesian evidence synthesis, the age-group-specific annual incidence of symptomatic infection with seasonal influenza in the Netherlands over the period 2005-2007. METHODS:The Netherlands population and age group distribution for 2006 defined the base population. The number of influenza-l...

journal_title：Influenza and other respiratory viruses

authors： McDonald SA,Presanis AM,De Angelis D,van der Hoek W,Hooiveld M,Donker G,Kretzschmar ME

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The Northern Territory (NT) of Australia has a mix of climates, sparsely distributed population and a large proportion of the populace are Indigenous Australians, and influenza is known to have a disproportionate impact upon this group. Understanding the epidemiology of influenza in this region would inform ...

journal_title：Influenza and other respiratory viruses

authors： Weinman AL,Sullivan SG,Vijaykrishna D,Markey P,Levy A,Miller A,Tong SYC

更新日期：2020-09-01 00:00:00

abstract：:We conducted two surveys to evaluate the health-seeking behaviors of individuals with acute respiratory infections (ARI) during the COVID-19 outbreak in Wuhan, China. Among 351 participants reporting ARI (10.3%, 351/3,411), 36.5% sought medical assistance. Children were more likely to seek medical assistance than othe...

journal_title：Influenza and other respiratory viruses

authors： Yang J,Gong H,Chen X,Chen Z,Deng X,Qian M,Hou Z,Ajelli M,Viboud C,Yu H

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Hospitalization burden associated with influenza and respiratory syncytial virus (RSV) is uncertain due to ambiguity in the inference methodologies employed for its estimation. OBJECTIVES:Utilization of a new method to quantitate the above burden. METHODS:Weekly hospitalization rates for several principal ...

journal_title：Influenza and other respiratory viruses

authors： Goldstein E,Greene SK,Olson DR,Hanage WP,Lipsitch M

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The relative ability of neuraminidase inhibitors (NAIs) to reduce household influenza transmission when given to index patients is not established. OBJECTIVES:To compare daily secondary infection rates (SIR) of influenza A (A/H1pdm and A/H3) and B in households of index patients treated with oseltamivir, za...

journal_title：Influenza and other respiratory viruses

authors： Hirotsu N,Saisho Y,Hasegawa T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Highly pathogenic H5N1 influenza viruses reemerged in humans in 2003 and have caused fatal human infections in Asia and Africa as well as ongoing outbreaks in poultry. These viruses have evolved substantially and are now so antigenically varied that a single vaccine antigen may not protect against all circul...

journal_title：Influenza and other respiratory viruses

authors： Ducatez MF,Webb A,Crumpton JC,Webby RJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:During April-July 2009, U.S. hospitalization rates for 2009 pandemic influenza A (H1N1) virus (H1N1pdm09) infection were estimated at 4·5/100 000 persons. We describe rates and risk factors for H1N1pdm09 infection among American Indians (AIs) in four isolated southwestern U.S. communities served by the India...

journal_title：Influenza and other respiratory viruses

authors： Suryaprasad A,Redd JT,Hancock K,Branch A,Steward-Clark E,Katz JM,Fry AM,Cheek JE,Influenza Serology Working Group.,American Indian and Alaska Native Pandemic Influenza A (H1N1) Investigation Team.

更新日期：2013-11-01 00:00:00

abstract：:Highly pathogenic avian influenza A H5N1 viruses remain a significant health threat to humans given the continued rare occurrence of human cases with a high case fatality rate. This brief literature review summarizes available evidence of risk factors for H5N1 infection in humans and updates a recent systematic review...

journal_title：Influenza and other respiratory viruses

authors： Van Kerkhove MD

更新日期：2013-09-01 00:00:00

abstract：:Sinovac Biotech started to develop prototype pandemic influenza H5N1 vaccines in March 2004. On 2 April 2008, Sinovac's inactivated, aluminium-adjuvanted, whole-virion prototype pandemic influenza A (H5N1) vaccine (PanFlu) was granted production licensure by the China regulatory authority State Food and Drug Administr...

journal_title：Influenza and other respiratory viruses

authors： Qiu YZ,Yin WD

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved and the inherent noisiness of serological data. RESULTS:I show that log-transformed serological data exist in an effectively one-dimensional space. I use this r...

journal_title：Influenza and other respiratory viruses

authors： Ndifon W

更新日期：2011-05-01 00:00:00