Abstract:
:A myriad of risk factors have been linked to an increase in the severity of the pandemic H1N1 2009 influenza A virus [A(H1N1)pdm09] including pregnancy and obesity where death rates can be elevated as compared to the general population. The goal of this review is to provide an overview of the influence of pregnancy and obesity on the reported cases of A(H1N1)pdm09 virus infection and of how the concurrent presence of these factors may have an exacerbating effect on infection outcome. Also, the hypothesized immunologic mechanisms that contribute to A(H1N1)pdm09 virus severity during pregnant or obese states are outlined. Identifying the mechanisms underlying the increased disease severity in these populations may result in improved therapeutic approaches and future pandemic preparedness.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Karlsson EA,Marcelin G,Webby RJ,Schultz-Cherry Sdoi
10.1111/j.1750-2659.2012.00342.xsubject
Has Abstractpub_date
2012-11-01 00:00:00pages
449-60issue
6eissn
1750-2640issn
1750-2659journal_volume
6pub_type
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journal_title:Influenza and other respiratory viruses
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doi:10.1111/j.1750-2659.2012.00355.x
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2009.00102.x
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2009.00128.x
更新日期:2010-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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abstract:BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00377.x
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12725
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Acute respiratory infections (ARIs) are a major cause of morbidity and mortality worldwide. Influenza typically contributes substantially to the burden of ARI, but only limited data are available on influenza activity and seasonality in Jordan. METHODS:Syndromic case definitions were used to identify indivi...
journal_title:Influenza and other respiratory viruses
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doi:10.1111/irv.12354
更新日期:2016-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12545
更新日期:2018-05-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12292
更新日期:2015-01-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12227
更新日期:2014-05-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,meta分析
doi:10.1111/j.1750-2659.2009.00124.x
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...
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pub_type: 历史文章,杂志文章
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journal_title:Influenza and other respiratory viruses
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doi:10.1111/irv.12014
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00423.x
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to be prioritised for influenza vaccination during any stage of pregnancy. The risk of seasonal influenza varies substantially throughout the year in temperate climates; however, there is limite...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,meta分析
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abstract:BACKGROUND:Since 2009, Thailand has recommended influenza vaccine for children aged 6 months through 2 years, but no estimates of influenza vaccine coverage or effectiveness are available for this target group. METHODS:During August 2011-May 2013, high-risk and healthy children aged ≤36 months were enrolled in a 2-yea...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12302
更新日期:2015-03-01 00:00:00
abstract::Progress in the development of antivirals for non-influenza respiratory viruses has been slow with the result that many unmet medical needs and few approved agents currently exist. This commentary selectively reviews examples of where specific agents have provided promising clinical benefits in selected target populat...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12612
更新日期:2019-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00246.x
更新日期:2011-11-01 00:00:00
abstract::Oseltamivir-resistant 2009 H1N1 influenza virus infections associated with neuraminidase (NA) H275Y have been identified sporadically. Strains possessing the hemagglutinin (HA) D222G mutation have been detected in small numbers of fatal 2009 H1N1 cases. We report the first clinical description of 2009 H1N1 virus infec...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00329.x
更新日期:2012-11-01 00:00:00