Abstract:
:ROPs constitute a family of plant-specific, RHO-like small GTPases that serve as molecular switches in a wide range of signaling pathways. The activities of ROPs are regulated by guanine nucleotide exchange factors (GEFs). ROP11, a member of the ROP GTPase family in Arabidopsis, is a negative regulator of multiple ABA responses. In this study, we show that ROPGEF1 and ROPGEF4 interact with ROP11 on plasma membranes in guard cells. Furthermore, our analyses of ROPGEF1/4 knockout mutants and overexpressing lines suggested that ROPGEF1 and ROPGEF4 are specific regulators of ROP11 function in ABA-mediated stomatal closure.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Li Z,Liu Ddoi
10.1016/j.febslet.2012.03.040subject
Has Abstractpub_date
2012-05-07 00:00:00pages
1253-8issue
9eissn
0014-5793issn
1873-3468pii
S0014-5793(12)00240-2journal_volume
586pub_type
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