Abstract:
:Caveolin is a protein present in membrane specializations termed caveolae where it may play a structural role. Previous studies on the cDNA sequence of chicken caveolin demonstrated that it is an integral membrane protein without significant homology to any known protein. The cDNA sequence of human lung caveolin is presented here. A striking sequence homology is observed with the chicken protein, as well as a very recently reported protein termed VIP21 [(1992) J. Cell Biol. 118, 1003-1014], a putative vesicle transport protein isolated from MDCK cells. Genomic Southern blots suggest that caveolin is present in a single copy, and Northern blots confirm that the caveolin mRNA is elevated in muscle.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Glenney JR Jrdoi
10.1016/0014-5793(92)81458-xkeywords:
subject
Has Abstractpub_date
1992-12-07 00:00:00pages
45-8issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(92)81458-Xjournal_volume
314pub_type
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