Increased forest ecosystem carbon and nitrogen storage from nitrogen rich bedrock.

abstract：:Many marine invertebrates and fish respond to hydrostatic pressure in order to regulate their depth and synchronize their behaviour to tidal cycles. Here we investigate the effect of hydrostatic pressure on the vestibular hair cells located in the labyrinth of the dogfish Scyliorhinus canicula, and find that it modula...

journal_title：Nature

authors： Fraser PJ,Shelmerdine RL

更新日期：2002-01-31 00:00:00

abstract：:The question of whether nicotine, the neuroactive compound of tobacco, is addictive has been open to considerable scientific and public discussion. Although it can serve as a positive reinforcer in several animal species, including man, nicotine is thought to be a weak reinforcer in comparison with addictive drugs suc...

journal_title：Nature

authors： Pontieri FE,Tanda G,Orzi F,Di Chiara G

更新日期：1996-07-18 00:00:00

abstract：:Satellite observations have transformed our understanding of the Antarctic cryosphere. The continent holds the vast majority of Earth's fresh water, and blankets swathes of the Southern Hemisphere in ice. Reductions in the thickness and extent of floating ice shelves have disturbed inland ice, triggering retreat, acce...

journal_title：Nature

authors： Shepherd A,Fricker HA,Farrell SL

更新日期：2018-06-01 00:00:00

abstract：:Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a stable latent reservoir, primarily in resting memory CD4(+) T cells. This reservoir presents a major barrier to the cure of HIV-1 infection. To purge the reservoir, pharmacological reactivation of latent HIV-1 has been proposed an...

journal_title：Nature

authors： Deng K,Pertea M,Rongvaux A,Wang L,Durand CM,Ghiaur G,Lai J,McHugh HL,Hao H,Zhang H,Margolick JB,Gurer C,Murphy AJ,Valenzuela DM,Yancopoulos GD,Deeks SG,Strowig T,Kumar P,Siliciano JD,Salzberg SL,Flavell RA,Shan

更新日期：2015-01-15 00:00:00

abstract：: ...

journal_title：Nature

authors： Clayton EW

更新日期：2018-12-01 00:00:00

abstract：:Defects in insulin signalling are among the most common and earliest defects that predispose an individual to the development of type 2 diabetes. MicroRNAs have been identified as a new class of regulatory molecules that influence many biological functions, including metabolism. However, the direct regulation of insul...

journal_title：Nature

authors： Trajkovski M,Hausser J,Soutschek J,Bhat B,Akin A,Zavolan M,Heim MH,Stoffel M

更新日期：2011-06-08 00:00:00

abstract：:The emergence and outgrowth of a population of tumour cells resistant to multiple drugs is a major problem in the chemotherapeutic treatment of cancer. We have used highly drug-resistant cell lines developed in vitro to study the molecular basis of multidrug resistance. In these cell lines high levels of resistance ar...

journal_title：Nature

authors： Gros P,Ben Neriah YB,Croop JM,Housman DE

更新日期：1986-10-23 00:00:00

abstract：:Crystalline materials are crucial to the function of living organisms, in the shells of molluscs, the matrix of bone, the teeth of sea urchins, and the exoskeletons of coccoliths. However, pathological biomineralization can be an undesirable crystallization process associated with human diseases. The crystal growth of...

journal_title：Nature

authors： Chung J,Granja I,Taylor MG,Mpourmpakis G,Asplin JR,Rimer JD

更新日期：2016-08-25 00:00:00

abstract：:Thomas et al. argue, contrary to Sala et al. that climate change poses an equal or greater threat to global biodiversity than land-use change. We contest this claim, however, on the grounds that Thomas et al. incorrectly apply species-area relationships. ...

journal_title：Nature

authors： Buckley LB,Roughgarden J

更新日期：2004-07-01 00:00:00

abstract：:The Haldane model on a honeycomb lattice is a paradigmatic example of a Hamiltonian featuring topologically distinct phases of matter. It describes a mechanism through which a quantum Hall effect can appear as an intrinsic property of a band structure, rather than being caused by an external magnetic field. Although p...

journal_title：Nature

authors： Jotzu G,Messer M,Desbuquois R,Lebrat M,Uehlinger T,Greif D,Esslinger T

更新日期：2014-11-13 00:00:00

abstract：:Adsorption-based phenomena are important in gas separations, such as the treatment of greenhouse-gas and toxic-gas pollutants, and in water-adsorption-based heat pumps for solar cooling systems. The ability to tune the pore size, shape and functionality of crystalline porous coordination polymers--or metal-organic fra...

journal_title：Nature

authors： Krause S,Bon V,Senkovska I,Stoeck U,Wallacher D,Többens DM,Zander S,Pillai RS,Maurin G,Coudert FX,Kaskel S

更新日期：2016-04-21 00:00:00

abstract：:We describe here a new view of primary visual cortex (V1) based on measurements of neural responses in V1 to patterns called 'illusory contours' (Fig. 1a, b). Detection of an object's boundary contours is a fundamental visual task. Boundary contours are defined by discontinuities not only in luminance and colour, but ...

journal_title：Nature

authors： Grosof DH,Shapley RM,Hawken MJ

更新日期：1993-10-07 00:00:00

abstract：:Neuropeptide Y (NPY) has a number of functions in mammalian physiology. Here we identify a role for NPY in promoting proliferation of postnatal neuronal precursor cells. NPY is synthesized in the postnatal olfactory epithelium by sustentacular cells, previously proposed to function only in structural support. Mice wit...

journal_title：Nature

authors： Hansel DE,Eipper BA,Ronnett GV

更新日期：2001-04-19 00:00:00

abstract：:The 3-A structure of DNA-binding protein II, which exhibits histone-like properties in bacteria, has been determined. The molecule is dimeric and appears to bind to the phosphate backbone of DNA through two symmetry-related arms. A mechanism by which the protein induces DNA supercoiling is proposed. ...

journal_title：Nature

authors： Tanaka I,Appelt K,Dijk J,White SW,Wilson KS

更新日期：1984-08-02 00:00:00

abstract：:The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly parallel sequencing system with raw throughput significantly greater than that of state-of-the-art capillary electrophoresis instruments. The...

journal_title：Nature

authors： Margulies M,Egholm M,Altman WE,Attiya S,Bader JS,Bemben LA,Berka J,Braverman MS,Chen YJ,Chen Z,Dewell SB,Du L,Fierro JM,Gomes XV,Godwin BC,He W,Helgesen S,Ho CH,Irzyk GP,Jando SC,Alenquer ML,Jarvie TP,Jirage K

更新日期：2005-09-15 00:00:00

abstract：:Holliday junctions (HJs) are key intermediates in homologous recombination and are especially important for the production of crossover recombinants. Bacterial RecA family proteins promote the formation and branch migration of HJs in vitro by catalysing a reciprocal DNA-strand exchange reaction between two duplex DNA ...

journal_title：Nature

authors： Murayama Y,Kurokawa Y,Mayanagi K,Iwasaki H

更新日期：2008-02-21 00:00:00

abstract：:A single base-pair mutation (beta s) in codon 6 of the human beta-globin gene, causing a single amino-acid substitution, is the cause of sickle cell anaemia. The mutant haemoglobin molecule, HbS, polymerizes when deoxygenated and causes deformation of the erythrocytes to a characteristic 'sickled' shape. Sickling of c...

journal_title：Nature

authors： Greaves DR,Fraser P,Vidal MA,Hedges MJ,Ropers D,Luzzatto L,Grosveld F

更新日期：1990-01-11 00:00:00

abstract：:The potential use of smallpox as a biological weapon has led to the production and stockpiling of smallpox vaccine and the immunization of some healthcare workers. Another public health goal is the licensing of a safer vaccine that could benefit the millions of people advised not to take the current one because they o...

journal_title：Nature

authors： Earl PL,Americo JL,Wyatt LS,Eller LA,Whitbeck JC,Cohen GH,Eisenberg RJ,Hartmann CJ,Jackson DL,Kulesh DA,Martinez MJ,Miller DM,Mucker EM,Shamblin JD,Zwiers SH,Huggins JW,Jahrling PB,Moss B

更新日期：2004-03-11 00:00:00

abstract：:A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same amino-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived fr...

journal_title：Nature

authors： Leung DW,Spencer SA,Cachianes G,Hammonds RG,Collins C,Henzel WJ,Barnard R,Waters MJ,Wood WI

更新日期：1987-12-10 00:00:00

abstract：:Genomic imprinting is an allele-specific gene expression system that is important for mammalian development and function. The molecular basis of genomic imprinting is allele-specific DNA methylation. Although it is well known that the de novo DNA methyltransferases Dnmt3a and Dnmt3b are responsible for the establishme...

journal_title：Nature

authors： Yamaguchi S,Shen L,Liu Y,Sendler D,Zhang Y

更新日期：2013-12-19 00:00:00

abstract：:AFTER exposure to secretagogues the small intestine changes from a tissue that absorbs fluid and electrolyte from lumen to blood into a tissue that secretes electrolyte and fluid into the lumen(1-4). It has been shown that this secretion results from an increase in the passive Cl(-) permeability of the mucosal border,...

journal_title：Nature

authors： Ilundain A,Naftalin RJ

更新日期：1979-05-31 00:00:00

abstract：:FokI is a member of an unusual class of bipartite restriction enzymes that recognize a specific DNA sequence and cleave DNA nonspecifically a short distance away from that sequence. Because of its unusual bipartite nature, FokI has been used to create artificial enzymes with new specificities. We have determined the c...

journal_title：Nature

authors： Wah DA,Hirsch JA,Dorner LF,Schildkraut I,Aggarwal AK

更新日期：1997-07-03 00:00:00

abstract：:When a person walks through a rigid environment while holding eyes and head fixed, the pattern of retinal motion flows radially away from a point, the focus of expansion (Fig. 1a). Under such conditions of translation, heading corresponds to the focus of expansion and people identify it readily. But when making an eye...

journal_title：Nature

authors： Royden CS,Banks MS,Crowell JA

更新日期：1992-12-10 00:00:00

abstract：:XX female mammals undergo transcriptional silencing of most genes on one of their two X chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is an example of epigenetic regulation. Once enacted in individual cells of the early female embryo, XCI is...

journal_title：Nature

authors： Kalantry S,Purushothaman S,Bowen RB,Starmer J,Magnuson T

更新日期：2009-07-30 00:00:00

abstract：:Haematopoietic stem cells (HSCs) have the ability to renew themselves and to give rise to all lineages of the blood; however, the signals that regulate HSC self-renewal remain unclear. Here we show that the Wnt signalling pathway has an important role in this process. Overexpression of activated beta-catenin expands t...

journal_title：Nature

authors： Reya T,Duncan AW,Ailles L,Domen J,Scherer DC,Willert K,Hintz L,Nusse R,Weissman IL

更新日期：2003-05-22 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：:The theory of reinforcement learning provides a normative account, deeply rooted in psychological and neuroscientific perspectives on animal behaviour, of how agents may optimize their control of an environment. To use reinforcement learning successfully in situations approaching real-world complexity, however, agents...

journal_title：Nature

authors： Mnih V,Kavukcuoglu K,Silver D,Rusu AA,Veness J,Bellemare MG,Graves A,Riedmiller M,Fidjeland AK,Ostrovski G,Petersen S,Beattie C,Sadik A,Antonoglou I,King H,Kumaran D,Wierstra D,Legg S,Hassabis D

更新日期：2015-02-26 00:00:00

abstract：:Obesity is now so common within the world's population that it is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health. In particular, obesity is associated with diabetes mellitus, coronary heart disease, certain forms of cancer, and sleep-breathing disorders. O...

journal_title：Nature

authors： Kopelman PG

更新日期：2000-04-06 00:00:00

abstract：:Particle physicists see neutrons as tiny massive particles with a confinement radius of about 0.7 fm and a distinct internal quark gluon structure. In quantum mechanics, neutrons are described by wave packets whose spatial extent may become ten orders of magnitude larger than the confinement radius, and can even reach...

journal_title：Nature

authors： Rauch H,Lemmel H,Baron M,Loidl R

更新日期：2002-06-06 00:00:00

abstract：:The well known trade-off between hardness and toughness (resistance to fracture) makes simultaneous improvement of both properties challenging, especially in diamond. The hardness of diamond can be increased through nanostructuring strategies1,2, among which the formation of high-density nanoscale twins - crystalline ...

journal_title：Nature

authors： Yue Y,Gao Y,Hu W,Xu B,Wang J,Zhang X,Zhang Q,Wang Y,Ge B,Yang Z,Li Z,Ying P,Liu X,Yu D,Wei B,Wang Z,Zhou XF,Guo L,Tian Y

更新日期：2020-06-01 00:00:00