相关文献
NATURE文献大全abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature
pub_type: 已发布勘误
doi:10.1038/s41586-020-2351-4
更新日期:2020-06-01 00:00:00
abstract::The taxonomy of a parasite can be an important guide to its pathogenic characteristics. A wide range of anatomical, biochemical and behavioural tests is now being developed to define different strains and subspecies of the main tropical parasites. ...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/273600a0
更新日期:1978-06-22 00:00:00
abstract::High-pressure transitions are thought to modify hydrogen molecules to a molecular metallic solid and finally to an atomic metal1, which is predicted to have exotic physical properties and the topology of a two-component (electron and proton) superconducting superfluid condensate2,3. Therefore, understanding such trans...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1565-9
更新日期:2019-09-01 00:00:00
abstract::The DNA polymerase V (pol V) and RecA proteins are essential components of a mutagenic translesion synthesis pathway in Escherichia coli designed to cope with DNA damage. Previously, it has been assumed that RecA binds to the DNA template strand being copied. Here we show, however, that pol-V-catalysed translesion syn...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature05042
更新日期:2006-08-24 00:00:00
abstract::In multinucleated heterokaryons formed from the fusion of differentiated muscle cells to either hepatocytes or fibroblasts, muscle-specific gene expression is activated, liver-specific gene expression is repressed, and there are changes in the location of the Golgi apparatus. An understanding of the regulatory mechani...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/344454a0
更新日期:1990-03-29 00:00:00
abstract::The interaction of lectins with carbohydrate receptors on the plasma membrane of eukaryotic cells results in a wide variety of biological effects. One effect which has been extensively studied is the stimulation of lymphocytes to blastogenesis and proliferation. High doses of concanavalin A (Con A) and phytohaemagglut...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/284273a0
更新日期:1980-03-20 00:00:00
abstract::The visual system analyses information by decomposing complex objects into simple components (visual features) that are widely distributed across the cortex. When several objects are present simultaneously in the visual field, a mechanism is required to group (bind) together visual features that belong to each object ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/28166
更新日期:1998-07-09 00:00:00
abstract::The origins of religion and of complex societies represent evolutionary puzzles1-8. The 'moralizing gods' hypothesis offers a solution to both puzzles by proposing that belief in morally concerned supernatural agents culturally evolved to facilitate cooperation among strangers in large-scale societies9-13. Although pr...
journal_title:Nature
pub_type: 历史文章,杂志文章
doi:10.1038/s41586-019-1043-4
更新日期:2019-04-01 00:00:00
abstract::A large number of high-accuracy vector measurements of the Earth's magnetic field have recently become available from the satellite Oersted, complementing previous vector data from the satellite Magsat, which operated in 1979/80. These data can be used to infer the morphology of the magnetic field at the surface of th...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature01879
更新日期:2003-08-14 00:00:00
abstract::Features that were once considered exclusive to modern birds, such as feathers and a furcula, are now known to have first appeared in non-avian dinosaurs. However, relatively little is known of the early evolutionary history of the hyperinflated brain that distinguishes birds from other living reptiles and provides th...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature12424
更新日期:2013-09-05 00:00:00
abstract::Rapidly advancing knowledge of genome structure and sequence enables new means for the analysis of specific DNA changes associated with the differences between the human brain and that of other mammals. Recent studies implicate evolutionary changes in messenger RNA and protein expression levels, as well as DNA changes...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04103
更新日期:2005-09-01 00:00:00
abstract::Tumour necrosis factor (TNF) elicits multiple biological effects through two distinct cell surface receptors, TNF-R1 (p55) and TNF-R2 (p75). Most TNF-mediated biological responses, such as cell death, gene induction, antiviral activity and cytokine production, have been attributed to TNF-R1 (refs 1-5). Gene targeting ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/372560a0
更新日期:1994-12-08 00:00:00
abstract::Protecting the world's freshwater resources requires diagnosing threats over a broad range of scales, from global to local. Here we present the first worldwide synthesis to jointly consider human and biodiversity perspectives on water security using a spatial framework that quantifies multiple stressors and accounts f...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09440
更新日期:2010-09-30 00:00:00
abstract::In the HTML version of this Letter, the affiliations for authors Andrew S. Azman, Dhirendra Kumar and Thandavarayan Ramamurthy were inverted (the PDF and print versions of the Letter were correct); the affiliations have been corrected online. ...
journal_title:Nature
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41586-019-0966-0
更新日期:2019-02-01 00:00:00
abstract::The radiation of the mammals provides a 165-million-year test case for evolutionary theories of how species occupy and then fill ecological niches. It is widely assumed that species often diverge rapidly early in their evolution, and that this is followed by a longer, drawn-out period of slower evolutionary fine-tunin...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10516
更新日期:2011-10-19 00:00:00
abstract::Mineralocorticoid secretion is predominantly controlled by the octapeptide angiotensin II, which exerts trophic actions on the adrenal glomerulosa and acute regulatory effects on aldosterone biosynthesis. The trophic actions include stimulation of angiotensin II receptors and enzymes of the aldosterone biosynthetic pa...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/289507a0
更新日期:1981-02-05 00:00:00
abstract::Amyloid beta-protein (AP) is a peptide of relative molecular mass (Mr) 42,000 found in the senile plaques, cerebrovascular amyloid deposits, and neurofibrillary tangles of patients with Alzheimer's disease and Down's syndrome (trisomy 21). Recent molecular genetic evidence has indicated that AP is encoded as part of a...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/329156a0
更新日期:1987-09-10 00:00:00
abstract::Neuromorphic computing draws inspiration from the brain to provide computing technology and architecture with the potential to drive the next wave of computer engineering1-13. Such brain-inspired computing also provides a promising platform for the development of artificial general intelligence14,15. However, unlike c...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-020-2782-y
更新日期:2020-10-01 00:00:00
abstract::Information--be it classical or quantum--is measured by the amount of communication needed to convey it. In the classical case, if the receiver has some prior information about the messages being conveyed, less communication is needed. Here we explore the concept of prior quantum information: given an unknown quantum ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature03909
更新日期:2005-08-04 00:00:00
abstract::The DNA synthetic (S) phase of cell division is about twice as long in human basal cell carcinoma (BCC) as the normal epidermis and several non-malignant skin diseases. A similar increase in S phase duration seems to occur in tumours of the human oesophagus, larynx and recto-colon. At the molecular level, the overall ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/285265a0
更新日期:1980-05-22 00:00:00
abstract::A timescale is necessary for estimating rates of molecular and morphological change in organisms and for interpreting patterns of macroevolution and biogeography. Traditionally, these times have been obtained from the fossil record, where the earliest representatives of two lineages establish a minimum time of diverge...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/31927
更新日期:1998-04-30 00:00:00
abstract::The neutron superfluid in most neutron stars should be in a highly turbulent state. If so, this turbulence drastically alters its rotational properties. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/227791a0
更新日期:1970-08-22 00:00:00
abstract::Scientific fraud, much in the news recently, is not a new phenomenon. What follows is a personal account of a particular case. ...
journal_title:Nature
pub_type: 传,历史文章,杂志文章
doi:10.1038/357434a0
更新日期:1992-06-11 00:00:00
abstract::Functioning and processing of membrane proteins critically depend on the way their transmembrane segments are embedded in the membrane. Sphingolipids are structural components of membranes and can also act as intracellular second messengers. Not much is known of sphingolipids binding to transmembrane domains (TMDs) of...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10742
更新日期:2012-01-09 00:00:00
abstract::The Haldane model on a honeycomb lattice is a paradigmatic example of a Hamiltonian featuring topologically distinct phases of matter. It describes a mechanism through which a quantum Hall effect can appear as an intrinsic property of a band structure, rather than being caused by an external magnetic field. Although p...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13915
更新日期:2014-11-13 00:00:00
abstract::Muscarinic receptors of cardiac pacemaker and atrial cells are linked to a potassium channel (IK.ACh) by a pertussis toxin-sensitive GTP-binding protein. The dissociation of G-proteins leads to the generation of two potential transducing elements, alpha-GTP and beta gamma. IK.ACh is activated by G-protein alpha- and b...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/337557a0
更新日期:1989-02-09 00:00:00
abstract::Protein G is a cell-surface protein from Streptococcus which binds to IgG molecules from a wide range of species with an affinity comparable to that of antigen. The high affinity of protein G for the Fab portion of IgG poses a particular challenge in molecular recognition, given the variability of heavy chain subclass...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/359752a0
更新日期:1992-10-22 00:00:00
abstract::The protein HLA-E is a non-classical major histocompatibility complex (MHC) molecule of limited sequence variability. Its expression on the cell surface is regulated by the binding of peptides derived from the signal sequence of some other MHC class I molecules. Here we report the identification of ligands for HLA-E. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35869
更新日期:1998-02-19 00:00:00
abstract::Thermodynamics predicts that transmembrane voltage modulates membrane tension and that this will cause movement. The magnitude and polarity of movement is governed by cell stiffness and surface potentials. Here we confirm these predictions using the atomic force microscope to dynamically follow the movement of voltage...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35096578
更新日期:2001-09-27 00:00:00
abstract::In the adult brain, new synapses are formed and pre-existing ones are lost, but the function of this structural plasticity has remained unclear. Learning of new skills is correlated with formation of new synapses. These may directly encode new memories, but they may also have more general roles in memory encoding and ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09946
更新日期:2011-05-26 00:00:00