Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Naturejournal_title
Natureauthors
Grishin E,Malamud U,Perets HB,Wandel O,Schäfer CMdoi
10.1038/s41586-020-2351-4subject
Has Abstractpub_date
2020-06-01 00:00:00pages
E2issue
7811eissn
0028-0836issn
1476-4687pii
10.1038/s41586-020-2351-4journal_volume
582pub_type
已发布勘误相关文献
NATURE文献大全abstract::Humoral immune responses to immunization and infection and susceptibilities to antibody-mediated autoimmunity are generally lower in males1-3. However, the mechanisms underlying such sexual dimorphism are not well understood. Here we show that there are intrinsic differences between the B cells that produce germinal c...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1873-0
更新日期:2020-01-01 00:00:00
abstract::Lipid-bilayer membranes supported on solid substrates are widely used as cell-surface models that connect biological and artificial materials. They can be placed either directly on solids or on ultrathin polymer supports that mimic the generic role of the extracellular matrix. The tools of modern genetic engineering a...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/nature04164
更新日期:2005-09-29 00:00:00
abstract::The assessment of changes in tropical cyclone activity within the context of anthropogenically influenced climate change has been limited by the short temporal resolution of the instrumental tropical cyclone record (less than 50 years). Furthermore, controversy exists regarding the robustness of the observational reco...
journal_title:Nature
pub_type: 历史文章,杂志文章
doi:10.1038/nature12882
更新日期:2014-01-30 00:00:00
abstract::The recent discovery that the human T-cell lymphoma leukemia virus (HTLV) may be the agent of transmission of T-cell lymphoid malignancies raises ethical questions for blood transfusion services. The effort to avoid use of contaminated blood is dependent to a large extent on the willingness and ability of donors to g...
journal_title:Nature
pub_type: 新闻
doi:10.1038/302567a0
更新日期:1983-04-14 00:00:00
abstract::Steroid hormone receptors are a class of cell-specific trans-acting transcription regulatory factors whose activity is controlled by specific binding of the hormone. The hormone-receptor complex appears to associate with promoter/enhancer elements of specific target genes, resulting in activation of transcription (see...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/325075a0
更新日期:1987-01-01 00:00:00
abstract::Achieving site selectivity in carbon-hydrogen (C-H) functionalization reactions is a long-standing challenge in organic chemistry. The small differences in intrinsic reactivity of C-H bonds in any given organic molecule can lead to the activation of undesired C-H bonds by a non-selective catalyst. One solution to this...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature12963
更新日期:2014-03-13 00:00:00
abstract::The primary function of the nerve cell is to process electrical signals. Over the past fifteen years there has been renewed interest in the detailed spatial analysis of signalling in individual neurons owing to experimental evidence that the regional electrical properties of neurons are complex. Thus the behaviour of ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/381322a0
更新日期:1996-05-23 00:00:00
abstract::Sex and recombination are widespread, but explaining these phenomena has been one of the most difficult problems in evolutionary biology. Recombination is advantageous when different individuals in a population carry different advantageous alleles. By bringing together advantageous alleles onto the same chromosome, re...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature05049
更新日期:2006-09-07 00:00:00
abstract::Seafloor spreading is largely unobserved because 98 per cent of the global mid-ocean-ridge system is below the ocean surface. Our understanding of the dynamic processes that control seafloor spreading is thus inferred largely from geophysical observations of spreading events on land at Afar in East Africa and Iceland....
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature20116
更新日期:2016-12-08 00:00:00
abstract::The hydroxyl radical (OH) is a key oxidant involved in the removal of air pollutants and greenhouse gases from the atmosphere. The ratio of Northern Hemispheric to Southern Hemispheric (NH/SH) OH concentration is important for our understanding of emission estimates of atmospheric species such as nitrogen oxides and m...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13721
更新日期:2014-09-11 00:00:00
abstract::Recent computational and psychological theories of human texture vision assert that texture discrimination is based on first-order differences in geometric and luminance attributes of texture elements, called 'textons'. Significant differences in the density, orientation, size, or contrast of line segments or other sm...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/333364a0
更新日期:1988-05-26 00:00:00
abstract::Variations in atmospheric radiocarbon (14C) concentrations can be attributed either to changes in the carbon cycle--through the rate of radiocarbon removal from the atmosphere--or to variations in the production rate of 14C due to changes in solar activity or the Earth's magnetic field. The production rates of 10Be an...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35046041
更新日期:2000-11-30 00:00:00
abstract::Although the first ten million years of whale evolution are documented by a remarkable series of fossil skeletons, the link to the ancestor of cetaceans has been missing. It was known that whales are related to even-toed ungulates (artiodactyls), but until now no artiodactyls were morphologically close to early whales...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06343
更新日期:2007-12-20 00:00:00
abstract::Molecular processes that govern pathogenic features of erythrocyte invasion and cytoadherence in malaria are reliant on Plasmodium-specific Duffy-binding-like domains (DBLs). These cysteine-rich modules recognize diverse host cell-surface receptors during pathogenesis. DBLs of parasite erythrocyte-binding proteins med...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04443
更新日期:2006-02-09 00:00:00
abstract::The largest products of magmatic activity on Earth, the great bodies of granite and their corresponding large eruptions, have a dual nature: homogeneity at the large scale and spatial and temporal heterogeneity at the small scale. This duality calls for a mechanism that selectively removes the large-scale heterogeneit...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09799
更新日期:2011-03-10 00:00:00
abstract::Landscapes modified by glacial erosion show a distinct distribution of surface area with elevation (hypsometry). In particular, the height of these regions is influenced by climatic gradients controlling the altitude where glacial and periglacial processes are the most active, and as a result, surface area is focused ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11786
更新日期:2013-01-10 00:00:00
abstract::The separation of cells into populations that do not intermix, termed compartments, is a fundamental organizing principle during development. Dorsal-ventral compartmentalization of the Drosophila wing is regulated downstream of the apterous (ap) gene, which encodes a transcription factor that specifies dorsal wing fat...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/46786
更新日期:1999-09-30 00:00:00
abstract::Much of our knowledge of galaxies comes from analysing the radiation emitted by their stars, which depends on the present number of each type of star in the galaxy. The present number depends on the stellar initial mass function (IMF), which describes the distribution of stellar masses when the population formed, and ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10972
更新日期:2012-04-25 00:00:00
abstract::Fluorescence polarization (FP) equilibrium binding assays differ from other types of binding studies in one important regard: they require no steps to separate free from bound tracer and are therefore fast, simple and accurate. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/375254a0
更新日期:1995-05-18 00:00:00
abstract::Genome instability is central to ageing, cancer and other diseases. It is not only proteins involved in DNA replication or the DNA damage response (DDR) that are important for maintaining genome integrity: from yeast to higher eukaryotes, mutations in genes involved in pre-mRNA splicing and in the biogenesis and expor...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13374
更新日期:2014-07-17 00:00:00
abstract::Planetary formation theories suggest that the giant planets formed on circular and coplanar orbits. The eccentricities of Jupiter, Saturn and Uranus, however, reach values of 6 per cent, 9 per cent and 8 per cent, respectively. In addition, the inclinations of the orbital planes of Saturn, Uranus and Neptune take maxi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature03539
更新日期:2005-05-26 00:00:00
abstract::The immunoglobulin superfamily is a group of proteins, each made of one or several domains sharing key structural features with either the variable (V) or the constant (C) immunoglobulin domains. It includes such functionally important members as the immunoglobulins themselves, major histocompatibility complex (MHC) c...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/328267a0
更新日期:1987-07-16 00:00:00
abstract::For cells of the innate immune system to mount a host defence response to infection, they must recognize products of microbial pathogens such as lipopolysaccharide (LPS), the endotoxin secreted by Gram-negative bacteria. These cellular responses require intracellular signalling pathways, such as the four MAP kinase (M...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/386296a0
更新日期:1997-03-20 00:00:00
abstract::Susceptibility of rodent cells to infection by ecotropic murine leukaemia viruses (MuLV) is determined by binding of the virus envelope to a membrane receptor that has multiple membrane-spanning domains. Cells infected by ecotropic MuLV synthesize envelope protein, gp70, which binds to this receptor, thereby preventin...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/352725a0
更新日期:1991-08-22 00:00:00
abstract::Carbon exchange between the terrestrial biosphere and the atmosphere is one of the key processes that need to be assessed in the context of the Kyoto Protocol. Several studies suggest that the terrestrial biosphere is gaining carbon, but these estimates are obtained primarily by indirect methods, and the factors that ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35009084
更新日期:2000-04-20 00:00:00
abstract::The discovery of Higgs-boson decays in a background of standard-model processes was assisted by machine learning methods. The classifiers used to separate signals such as these from background are trained using highly unerring but not completely perfect simulations of the physical processes involved, often resulting i...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature24047
更新日期:2017-10-18 00:00:00
abstract::The Gamburtsev Subglacial Mountains are the least understood tectonic feature on Earth, because they are completely hidden beneath the East Antarctic Ice Sheet. Their high elevation and youthful Alpine topography, combined with their location on the East Antarctic craton, creates a paradox that has puzzled researchers...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10566
更新日期:2011-11-16 00:00:00
abstract::Medawar has suggested that the major histocompatibility gene complex (MHC) might be involved in the contact inhibition of movement shown by fibroblasts and epithelia. Contact inhibition of movement is that reaction of cells which stops the movement of one cell over another and thus leads to monolayering and other feat...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/281222a0
更新日期:1979-09-20 00:00:00
abstract:: ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/d41586-018-07209-z
更新日期:2018-11-01 00:00:00
abstract:: ...
journal_title:Nature
pub_type: 评论,社论
doi:10.1038/d41586-019-00483-5
更新日期:2019-02-01 00:00:00