Abstract:
:Interactions between the T-cell receptor (TCR) and self-peptide-MHC (spMHC) have been hypothesized to modulate T-cell reactivity in the periphery. Recent studies examining CD4+ T-cell responses to spMHC class II describe apparently contradictory findings and arrive at opposite conclusions. One explanation for these seemingly disparate results could be the use of mice that were assumed to be MHC class II null but might express some uncommon MHC class II heterodimers.
journal_name
Trends Immunoljournal_title
Trends in immunologyauthors
Ge Q,Bai A,Shen CH,Eisen HN,Chen Jdoi
10.1016/s1471-4906(03)00060-7keywords:
subject
Has Abstractpub_date
2003-04-01 00:00:00pages
186-9issue
4eissn
1471-4906issn
1471-4981pii
S1471490603000607journal_volume
24pub_type
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