Abstract:
:Lymphoid cell infiltration of periodontal tissues undergoing pathological destruction suggests a functional interdependence between connective tissue proteins such as collagen, fibronectin and elastin and mononuclear cells, mainly T lymphocytes. The aim of the study was to assess T lymphocyte proliferation after stimulation by mAb OKT3 and then costimulation by ECM (extracellular matrix) proteins, as well as T-cell adhesion to connective tissue proteins in patients with adult periodontitis, early-onset periodontitis, chronic gingivitis and experimental gingivitis. Controls included patients with clinically healthy periodontium. Statistical analysis of results showed a significantly decreased level of T lymphocyte proliferation in response to costimulating action of ECM proteins among patients with adult periodontitis as compared to the control group. Reactivity of T-cells was much higher in experimental gingivitis than in adult periodontitis, and significantly lower in chronic gingivitis than in controls. In addition, T-cell interaction with ECM proteins was abnormal in early-onset periodontitis patients, but was not statistically significant.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Słotwińska SM,Górski A,Wierzbicka M,Dybizbański E,Mrowiec T,Iwanicka-Frankowska Edoi
10.1016/s0165-2478(98)00060-1subject
Has Abstractpub_date
1998-10-01 00:00:00pages
131-4issue
3eissn
0165-2478issn
1879-0542pii
S0165247898000601journal_volume
63pub_type
杂志文章abstract::Numerous studies have dealt with occurrence of dendritic cells in various nonlymphoid organs such as kidney, liver or heart, whereas lymphocyte patterns in these organs have not been analyzed in detail. In the present study, leukocytes were quantified as cells/mm2 in the perivascular, interstitial and parenchymal tiss...
journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
pub_type: 杂志文章
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更新日期:1988-11-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2014.03.009
更新日期:2014-07-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
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更新日期:1996-06-01 00:00:00
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更新日期:2008-12-22 00:00:00
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journal_title:Immunology letters
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doi:10.1016/j.imlet.2014.09.007
更新日期:2015-02-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(94)90201-1
更新日期:1994-04-01 00:00:00
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
pub_type: 杂志文章
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
pub_type: 杂志文章
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2008.03.006
更新日期:2008-06-15 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
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