Abstract:
:Secondary lymphoid organs (SLO) are crucial structures for immune-surveillance and rapid immune responses allowing resident lymphocytes to encounter antigen-presenting cells that carry antigens from peripheral tissues. These structures develop during embryonic life through a tightly regulated process that involves interactions between haematopoietic and mesenchymal cells. Importantly, this morphogenesis potential is maintained throughout life since in chronic inflammatory conditions novel "tertiary lymphoid organs" can be generated by processes that are reminiscent of embryonic SLO development. In this review we will discuss early events in SLO morphogenesis, focusing on haematopoietic and mesenchymal cell subsets implicated on the development of lymphoid organs.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Coles M,Veiga-Fernandes Hdoi
10.1016/j.imlet.2013.08.001subject
Has Abstractpub_date
2013-11-01 00:00:00pages
46-53issue
1-2eissn
0165-2478issn
1879-0542pii
S0165-2478(13)00103-Xjournal_volume
156pub_type
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journal_title:Immunology letters
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journal_title:Immunology letters
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pub_type: 杂志文章,评审
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journal_title:Immunology letters
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2014.07.013
更新日期:2014-11-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/j.imlet.2007.11.015
更新日期:2008-02-15 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/s0165-2478(98)00153-9
更新日期:1999-03-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(84)90042-7
更新日期:1984-01-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2014.03.009
更新日期:2014-07-01 00:00:00
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journal_title:Immunology letters
pub_type: 信件
doi:10.1016/j.imlet.2009.08.004
更新日期:2009-09-22 00:00:00
abstract::The surface phenotypes of lymphoid cells in the developing embryonic thymus were characterized by using monoclonal antibodies. FT-2 antigen thus defined was predominantly expressed on thymocytes in the earlier embryonic stages in all the inbred mouse strains tested. The immunofluorescence and immunoperoxidase tests in...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(85)90004-5
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journal_title:Immunology letters
pub_type: 杂志文章
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journal_title:Immunology letters
pub_type: 杂志文章,评审
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journal_title:Immunology letters
pub_type: 杂志文章,评审
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更新日期:2008-03-15 00:00:00
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journal_title:Immunology letters
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journal_title:Immunology letters
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journal_title:Immunology letters
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pub_type: 杂志文章,评审
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更新日期:2002-06-03 00:00:00