Non-peptidic delta-opioid receptor antagonists suppress mitogen-induced tryptophan degradation in peripheral blood mononuclear cells in vitro.

abstract：:Using embryonic chickens treated with testosterone propionate, the effects of congenital absence of the bursa of Fabricius determined by the frequency of J chain-positive cells was examined in the spleen, thymus and bone marrow at the embryonic and newly hatched stages. J chain-positive cells in the chicks without bur...

journal_title：Immunology letters

authors： Moriya O,Ichikawa Y

更新日期：1984-01-01 00:00:00

abstract：:Applying 2 M KBr, membranes of Ehu were solubilized. By C3-affinity chromatography an activity could be isolated that inhibited the immune adherence reaction and C3b-dependent rosette formation. Since this material did not agglutinate EAC14oxy23b we termed it monovalent C3b receptor (mC3bR). PAGE and SDS-PAGE and stai...

journal_title：Immunology letters

authors： Mussel HH,Ehlen T,Schmitt M,Kazatchkine MD,Neyses L,Dierich MP

更新日期：1982-01-01 00:00:00

abstract：:The three-dimensional structures of cyclosporin A complexed with cyclophilin A or Fab fragment of a monoclonal antibody were compared. In these two complexes conformations of the fragment D-alanine8-N-methylvaline11 in cyclosporin A were in a good agreement. In addition, cyclophilin A and the Fab fragment had related ...

journal_title：Immunology letters

authors： Denesyuk AI,Lundell J,Zav'yalov V,Korpela T

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:Cytokine production from activated T cells play a pathogenetic role in mucosal lesions of coeliac disease (CD). Active interleukin (IL)-18 is expressed in the small intestinal mucosa in CD but not in healthy controls. IL-18 enhances intercellular adhesion molecule-1 (ICAM-1) expression. We analyzed IL-18 ser...

journal_title：Immunology letters

authors： Merendino RA,Di Pasquale G,Sturniolo GC,Ruello A,Albanese V,Minciullo PL,Di Mauro S,Gangemi S

更新日期：2003-02-03 00:00:00

abstract：:Pertussis, or whooping cough, has recently reemerged as a major public health threat despite high levels of vaccination. The development of a novel pertussis vaccine, especially an intranasal (i.n.) vaccine is undoubtedly necessary, and mucosal adjuvants have been explored to enhance the immune response. In the presen...

journal_title：Immunology letters

authors： Shi W,Kou Y,Jiang H,Gao F,Kong W,Su W,Xu F,Jiang C

更新日期：2018-06-01 00:00:00

abstract：:Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tes...

journal_title：Immunology letters

authors： Görög G,Laskay T,Petrányi GG

更新日期：1985-01-01 00:00:00

abstract：:After exposure to a concanavalin A (Con A)-unreactive variant of alpha 1-acid glycoprotein (AGP), macrophages released an inhibitor of interleukin-1 (IL-1) proliferative activity in the thymocyte comitogenic assay. This effect was observed with AGP concentrations above 100 micrograms/ml in the macrophage supernatant a...

journal_title：Immunology letters

authors： Bories PN,Kodari E,Feger J,Rouzeau JD,Agneray J,Durand G

更新日期：1990-10-01 00:00:00

abstract：:Interferon inducible transmembrane protein (IFITM) family genes have been implicated in several cellular processes such as the homotypic cell adhesion functions of IFNs and cellular anti-proliferative activities. We previously showed that the IFITM3 single nucleotide polymorphisms (SNPs) associated with susceptibility...

journal_title：Immunology letters

authors： Mo JS,Na KS,Yu JI,Chae SC

更新日期：2013-11-01 00:00:00

abstract：:The anaerobic bacterium Campylobacter pylori (Cp) is thought to be associated with chronic gastritis. This paper presents clinical data underpinning this view. Five patients with histological chronic gastritis as determined by diagnostic endoscopy, which was associated with Cp as determined by positive biopsy cultures...

journal_title：Immunology letters

authors： van Bohemen CG,Langenberg ML,Rauws EA,Oudbier J,Weterings E,Zanen HC

更新日期：1989-01-15 00:00:00

abstract：:Using the method of estimation of alpha-helical and beta-folded types of secondary structure from amino acid composition, it has been established that interferons contain about 60-70% of alpha-helices and not more than 10-20% of beta-structure. The same result was obtained using empirical and stereochemical rules for ...

journal_title：Immunology letters

authors： Zav'yalov VP,Denesyuk AI

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Vitamin D (vitD) is involved in important regulatory functions of the innate and adaptive immune system. So, it has been hypothesized that vitD might influence the course of atopic dermatitis (AD). Also obesity may have impact on immune system. The aim of our study was to investigate vitamin D status and bod...

journal_title：Immunology letters

authors： D'Auria E,Barberi S,Cerri A,Boccardi D,Turati F,Sortino S,Banderali G,Ciprandi G

更新日期：2017-01-01 00:00:00

abstract：:Transplantation immunologists have long been intrigued by the natural allograft that results from normal mammalian pregnancy. Its general success contrasts with the rejection problems associated with most artifactual organ transplantation and raises intriguing questions concerning the nature of the mechanisms involved...

journal_title：Immunology letters

authors： Wegmann TG

更新日期：1988-04-01 00:00:00

abstract：:Early diagnosis and immediately started appropriate treatment are mandatory for the prevention of radiographic progression, functional disability and unfavourable disease outcome in rheumatoid arthritis (RA). The current classification criteria for RA include two different types of biomarkers representing inflammatory...

journal_title：Immunology letters

authors： Nakken B,Papp G,Bosnes V,Zeher M,Nagy G,Szodoray P

更新日期：2017-09-01 00:00:00

abstract：:The mechanism of cytolysis by natural killer cells has been shown to involve a soluble lytic factor - the natural killer cytotoxic factor (NKCF). We have investigated the generation of NKCF on exposure of subpopulations of human blood lymphocytes to autologous B lymphocytes and EBV infected B lymphocytes (BEBV), and t...

journal_title：Immunology letters

authors： Saranath D,Masucci MG,Klein E

更新日期：1986-03-01 00:00:00

abstract：:A docile substrain of lymphocytic choriomeningitis virus (LCMV) causes a persistent infection in adult C3HeB mice and induces a severe autoimmune hemolytic anemia (AIHA) which is maximal around three weeks post infection (PI). Evaluations of serum immunoglobulin levels of these mice demonstrated grossly elevated IgG2a...

journal_title：Immunology letters

authors： Stellrecht KA,Vella AT

更新日期：1992-02-15 00:00:00

abstract：:Both, HIV envelope proteins gp120 and gp41 can directly activate complement system, even in the absence of HIV-specific antibodies. During the budding process HIV acquires host membrane-associated molecules among these complement regulatory proteins (CRPs). The presence of CRPs on the viral surface rescues HIV from co...

journal_title：Immunology letters

authors： Bánki Z,Stoiber H,Dierich MP

更新日期：2005-03-15 00:00:00

abstract：:This study tested the hypothesis that the Vδ3 subset of human γδ T cells, like their Vδ2 counterparts, can influence differentiation, antibody secretion and cytokine production by B cells. Vδ3 T cells constitute a minor subset of peripheral blood lymphocytes but are enriched in the liver and gut and are expanded in pa...

journal_title：Immunology letters

authors： Petrasca A,Melo AM,Breen EP,Doherty DG

更新日期：2018-04-01 00:00:00

abstract：:Thymocyte development requires an integration of extracellular cues to enforce lineage commitment at multiple defined checkpoints in a stage-specific manner. Critical signals from the pre-TCR, Notch, and the receptor for interleukin-7 (IL-7) dictate cellular differentiation from the CD4(-)CD8(-) (double negative) stag...

journal_title：Immunology letters

authors： Juntilla MM,Koretzky GA

更新日期：2008-03-15 00:00:00

abstract：:A panel of synthetic peptides representing human lymphocyte antigen (HLA) B8, other class I and class II restricted T cell epitopes and two B cell epitopes, were all able to compete with recognition of a HLA B8 restricted epitope by a cytotoxic T cell clone. Competition was obtained when the competitor peptides were a...

journal_title：Immunology letters

authors： Fernan A,Burrows SR,Moss DJ,Saul A,Suhrbier A

更新日期：1991-11-01 00:00:00

abstract：:In this study, we tried to establish a relationship between the immunopotentiating effects and the antioxidant activity of the immunostimulating compound, diethyldithiocarbamate (DDC). We studied the effects of DDC treatment on enriched T and B murine spleen lymphocytes in an in vivo-ex vivo model of O2-induced immune...

journal_title：Immunology letters

authors： Lacombe P,Carre I,Fay M,Pocidalo JJ

更新日期：1988-06-01 00:00:00

abstract：:Thymocyte conditioned medium (TCM) was prepared using 2 lots of fetal calf, and 1 lot each of horse and rabbit sera. The 4 TCM and the respective sera alone were compared in their ability to support primary in vitro sensitization to sheep red blood cells (SRBC) as assayed by direct plaque formation. As would be expect...

journal_title：Immunology letters

authors： White LL,Smith RA

更新日期：1987-01-01 00:00:00

abstract：:Phagocytosis of latex beads by peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that adrenocorticotropic hormone (ACTH) suppressed phagocytosis in a dose-dependent manner. ACTH (1-24) was more suppressive than ACTH (1-39). Control phagocytosis was partially suppressed in Ca(2+)...

journal_title：Immunology letters

authors： Ichinose M,Sawada M,Maeno T

更新日期：1994-10-01 00:00:00

abstract：:It is well known that most physiological functions change with aging, including the immune response. Data concerning the aging of lymphocyte subpopulations are conflicting. The antigen density of peripheral blood lymphocytes has been determined by fluorescently tagged OKT-3, OKT-4, OKT-8, OKT-11 and OKM1 monoclonal an...

journal_title：Immunology letters

authors： Varga Z,Bressani N,Zaia AM,Bene L,Fülöp T,Leövey A,Fabris N,Damjanovich S

更新日期：1990-02-01 00:00:00

abstract：:The human matrix metalloproteinases (MMPs) are importantly involved in aneurysm formation. Since the clinical manifestations in Behçet disease (BD) include aneurysm formation among major symptoms, polymorphisms in MMP-9 might be associated with BD susceptibility. The aim of the current case-control study was to invest...

journal_title：Immunology letters

authors： Naouali A,Kaabachi W,Tizaoui K,Amor AB,Hamzaoui A,Hamzaoui K

更新日期：2015-03-01 00:00:00

abstract：:Liposome-encapsulated conalbumin (L(conalbumin)) is an antigen that is efficiently phagocytosed by bone marrow-derived macrophages and presented to effector cells as part of the major histocompatibility complex (MHC) class I complex. In this report, we show that the conalbumin component of L(conalbumin) is degraded to...

journal_title：Immunology letters

authors： Rothwell SW,Wassef NM,Alving CR,Rao M

更新日期：2000-10-03 00:00:00

abstract：:The influence of human recombinant granulocyte-macrophage colony-stimulating factor (rH GM-CSF) on respiratory burst response of isolated human neutrophils was examined. Preincubation of cells with rH GM-CSF significantly increased the respiratory burst in response to formyl-methionyl-leucyl-phenylalanine (FMLP), meas...

journal_title：Immunology letters

authors： Leino L,Nuutila J,Pelliniemi TT,Rajamäki A

更新日期：1993-09-01 00:00:00

abstract：:The cytotoxicity of natural killer (NK) and lymphokine activated killer (LAK) cells against two human bladder tumor cell lines (BT-A and BT-B) was investigated using a fluorometric assay by labeling tumor cell DNA with Hoechst dye No. 33342. Our results demonstrate that BT-A and BT-B cells have low sensitivity to the ...

journal_title：Immunology letters

authors： Wang MH,Flad HD,Böhle A,Chen YQ,Ulmer AJ

更新日期：1991-03-01 00:00:00

abstract：:CD24 is an extensively glycosylated membrane protein that is linked to the membrane via a glycosyl-phosphatidylinositol (GPI)-anchor. In mice, CD24 is expressed by hematopoietic and non-hematopoietic cells. CD24-/- mice do not have gross immunological defects, but detailed analysis revealed strongly reduced responses ...

journal_title：Immunology letters

authors： Bretz NP,Salnikov AV,Doberstein K,Garbi N,Kloess V,Joumaa S,Naumov I,Boon L,Moldenhauer G,Arber N,Altevogt P

更新日期：2014-09-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) can often lead to many life-threatening diseases. It has the ability to invade normal endovascular tissue. Acute inflammation and its resolution are important to ensure bacterial clearance and limit tissue injury. Carbon monoxide (CO) has been shown to exert anti-inflammatory effects ...

journal_title：Immunology letters

authors： Tsai MH,Yang CM,Chang KT,Chuang CC,Lin WN,Jiang RS,Wu CH,Lee IT

更新日期：2018-11-01 00:00:00

abstract：:It remains unclear whether lipopolysaccharide (LPS) pre-treatment, which prevents Th2-type responses via Toll-like receptor 4 (TLR4), inhibits anaphylaxis. To determine the dose-dependent effects of LPS pre-treatment on anaphylactic decreases in rectal temperature caused by ovalbumin (OVA) re-exposure in immunized mic...

journal_title：Immunology letters

authors： Shiva D,Matsumoto T,Kremenik MJ,Kato Y,Yano H

更新日期：2008-06-15 00:00:00