A macrophage-derived factor induced by alpha 1-acid glycoprotein that inhibits IL-1 comitogenic activity.

abstract：:Naive CD4 T cells differentiate into functionally distinct T helper (Th) cells subsets or into regulatory T (Treg) cells in response to the cytokine milieu in which they encounter antigen. A recurring theme in post-thymic CD4 T cell differentiation is the cross-regulation of lineage choice by cytokines and transcripti...

journal_title：Immunology letters

authors： Hadjur S,Bruno L,Hertweck A,Cobb BS,Taylor B,Fisher AG,Merkenschlager M

更新日期：2009-01-29 00:00:00

abstract：:This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Immunology letters

authors： Karimabad MN,Falahati-Pour SK,Hassanshahi G,Koochakzadeh L

更新日期：2017-08-26 00:00:00

abstract：:The T cell receptor of gamma delta is normally expressed on a small percentage of peripheral lymphocytes. Although the role of gamma delta T cells in the physiologic immune response is still unknown, there is accumulating evidence that gamma delta T cells may participate in the immune response to mycobacterial and oth...

journal_title：Immunology letters

authors： Ho M,Webster HK,Tongtawe P,Pattanapanyasat K,Weidanz WP

更新日期：1990-08-01 00:00:00

abstract：:CD8 T cells are strongly induced in response to certain strains of vaccinia virus (VACV) and the generation of this population is tightly regulated by two Tumor Necrosis Factor (TNF)/TNFR superfamily members, OX40 (CD134) and CD27. In this study, we examined the role of another member of the TNFR superfamily, 4-1BB (C...

journal_title：Immunology letters

authors： Zhao Y,Croft M

更新日期：2012-01-30 00:00:00

abstract：:Intravenous infusion of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF), induced fatal anaphylactoid reaction in guinea pigs, or reversible thrombocytopenia and leucopenia. These reactions showed a maximal depression of circulating platelet and leucocyte numbers...

journal_title：Immunology letters

authors： Demopoulos CA,Tsabikakis GE,Kapoulas VM

更新日期：1981-08-01 00:00:00

abstract：:For more than two decades, chloroquine (CQ) was largely and deliberately used as first choice drug for malaria treatment. However, worldwide increasing cases of resistant strains of Plasmodium have hampered its use. Nevertheless, CQ has recently been tested as adjunct therapy in several inflammatory situations, such a...

journal_title：Immunology letters

authors： Thomé R,Lopes SC,Costa FT,Verinaud L

更新日期：2013-06-01 00:00:00

abstract：:The assessment strategy for implementation of the Union of European Medical Specialists' (UEMS) Immunology curriculum is based on a combination of formative and summative assessments. The strategy comprises a combination of workplace-based assessments and knowledge-based assessments designed to ensure acquisition of k...

journal_title：Immunology letters

authors： Choremi-Papadopoulou E,Faure GC,Malenica B,Misbah SA,Zlabinger GJ

更新日期：2009-06-30 00:00:00

abstract：:Pathogens in general and pathogenic viruses in particular have evolved a myriad of mechanisms to escape the immune response of mammalian species. Viruses that cause acute disease tend to bear characteristics that make them very contagious, as survival does not derive from chronicity of infection, but spread of disease...

journal_title：Immunology letters

authors： Toka FN,Golde WT

更新日期：2013-05-01 00:00:00

abstract：:Replication-competent retroviruses are not known to encode or induce nuclear antigens that are immunogenic in their natural hosts. We describe here the detection of a human T-lymphotropic virus (type I and type II) associated nuclear antigen (HTLV-NA) by an anticomplement immunofluorescence assay. Antibody to HTLV-NA ...

journal_title：Immunology letters

authors： Lee TH,Essex M,Klein E,Klein G

更新日期：1986-08-01 00:00:00

abstract：:Angiogenic and poorly angiogenic tumor variants were obtained by an intraperitoneal inoculation of cells from clones of polyoma-virus transformed BALB/c 3T3 cells into syngeneic mice. The angiogenic tumor cells expressed a higher tumorigenicity phenotype and a higher capacity to produce artificial pulmonary metastases...

journal_title：Immunology letters

authors： Sagi-Assif O,Traister A,Katz BZ,Anavi R,Eskenasy M,Witz IP

更新日期：1996-12-01 00:00:00

abstract：:Interleukin-37 (IL-37) has been identified as a novel anti-inflammatory cytokine. The present study aimed to evaluate the expression of IL-37 in serum and in peritoneal fluid to determine its clinical significance in endometriosis. Enzyme-linked immunosorbent assay (ELISA) was performed to examine serum IL-37 levels i...

journal_title：Immunology letters

authors： Kaabachi W,Kacem O,Belhaj R,Hamzaoui A,Hamzaoui K

更新日期：2017-05-01 00:00:00

abstract：:In this study the effect of PHA activation on the phosphatase activity of CD45 has been investigated in human leukemic T-cell lines. It has been found that in vivo activation of the cells with PHA resulted in 2-4-fold increase in enzyme activity. Addition of PHA to the postnuclear supernatant of cell lysates also resu...

journal_title：Immunology letters

authors： Monostori E,Hartyani Z,Ocsovszky I,Hegedus Z,Oravecz T,Kalman M,Ando I

更新日期：1994-10-01 00:00:00

abstract：:Protozoa of the genus Leishmania are intracellular parasites of macrophages and may cause diverse clinical forms of leishmaniasis, including cutaneous, diffuse cutaneous, mucocutaneous and visceral leishmaniasis. Infection with L. major in mice indicates that a protective immune response is achieved when Th1 cells are...

journal_title：Immunology letters

authors： Hernández MX,Barçante TA,Vilela L,Tafuri WL,Afonso LC,Vieira LQ

更新日期：2006-05-15 00:00:00

abstract：:In the following study we have analyzed cytokine secretion of T-cells of suicidal and non-suicidal depressed patients and healthy controls. It was found that T-cells of suicidal depressed patients have Th1 characteristics, while T-cells of non-suicidal depressed patients have Th2 characteristics. Th1 environment is as...

journal_title：Immunology letters

authors： Mendlovic S,Mozes E,Eilat E,Doron A,Lereya J,Zakuth V,Spirer Z

更新日期：1999-04-01 00:00:00

abstract：:Based on the cerebral malaria coma scale, 39 falciparum malaria autopsy cases from the Hospital for Tropical Diseases, Mahidol University, Bangkok, Thailand were divided into two groups of patients that had either cerebral malaria or non-cerebral malaria. We then studied significant pathological differences, such as p...

journal_title：Immunology letters

authors： Riganti M,Pongponratn E,Tegoshi T,Looareesuwan S,Punpoowong B,Aikawa M

更新日期：1990-08-01 00:00:00

abstract：:To test whether apoptotic thymocytes can be identified by altered packing of lipids in their plasma membranes, thymocytes were isolated from mice injected with hydrocortisone and stained with merocyanine 540 (MC540), a fluorescent probe sensitive to lipid packing. At 9-10 h after injection, a subpopulation of H2-Klo c...

journal_title：Immunology letters

authors： Schlegel RA,Stevens M,Lumley-Sapanski K,Williamson P

更新日期：1993-06-01 00:00:00

abstract：:Different splice variants of the CD44 cell-surface molecule have been linked to metastasis formation in several animal and human cancers. We have used metastatic CSML-100 and non-metastatic CSML-0 mouse adenocarcinoma cell lines to determine whether variant CD44 molecules could be implicated in the different behaviour...

journal_title：Immunology letters

authors： Tkach T,Li E,Bestagno M,Burrone OR

更新日期：1996-09-01 00:00:00

abstract：:A major factor in the ability of the placenta to avoid allograft rejection is the differential expression of MHC class I antigens on its surface. Using monoclonal antibodies and the electron microscopic immunogold technique, we have demonstrated that only the pregnancy-associated (Pa) antigen, which carries a broadly ...

journal_title：Immunology letters

authors： Kanbour A,Macpherson TA,Kunz HW,Gill TJ 3rd

更新日期：1987-12-01 00:00:00

abstract：:A variety of cell types may be involved in the regulation of IgA secretion at the intestinal mucosa. Intestinal epithelial cells (IEC) are known to have the capacity to secrete several cytokines which may exert an important regulatory effect on local immunoglobulin secretion by mucosal B cells. In this study, we have ...

journal_title：Immunology letters

authors： Goodrich ME,McGee DW

更新日期：1999-03-15 00:00:00

abstract：:Humans frequently produce serum IgM autoantibodies reactive with T-cell receptor beta chains at a determinant defined by peptides corresponding to the first complementarity determining region. It is likely that this determinant serves as a public idiotype involved in immunoregulation. Following screening of culture su...

journal_title：Immunology letters

authors： Dedeoglu F,Kaymaz H,Klein G,Marchalonis JJ

更新日期：1993-11-01 00:00:00

abstract：:The expression of antigen presenting MHC class I molecules can be enhanced through cytokines, e.g. upon infection with bacteria or viruses, either directly by enhancing class I gene transcription or by increasing the amounts of accessory proteins of the loading complex. Tapasin plays a significant role in the peptide ...

journal_title：Immunology letters

authors： Abarca-Heidemann K,Friederichs S,Klamp T,Boehm U,Guethlein LA,Ortmann B

更新日期：2002-10-01 00:00:00

abstract：:Allogeneic, H-2-incompatible irradiation chimeras (H-2d leads to H-2b) constructed with normal, unmanipulated bone marrow and with marrow-derived factors live long and do not manifest a GvH disease. Their response to primary immunization is deficient but their alloreactivity is normal. This chimeric allotolerance cann...

journal_title：Immunology letters

authors： Pierpaoli W,Maestroni GJ

更新日期：1983-04-01 00:00:00

abstract：:Blood coagulation and inflammation pathways are linked in many aspects. A number of serum factors involved in coagulation cascades affect directly or indirectly inflammatory responses, whereas proinflammatory cytokines influence blood coagulation pathways. In this work we demonstrated that thrombin is an effective sti...

journal_title：Immunology letters

authors： Suk K,Cha S

更新日期：1999-04-15 00:00:00

abstract：:A consensus motif for a bovine major histocompatibility complex (MHC) class I molecule, A20, was derived from parainfluenza type-3 (PI-3) virus-infected muscle-derived fibroblast cells and peripheral blood leukocytes by extraction of the naturally processed peptides from MHC class I molecules by treatment with TFA and...

journal_title：Immunology letters

authors： Bamford AI,Douglas A,Friede T,Stevanovic S,Rammensee HG,Adair BM

更新日期：1995-02-01 00:00:00

abstract：:Natural Killer (NK) cells were discovered when research on T cells produced an unexplained background, or "natural" cytotoxicity in non-immunized mice. The previously unknown cells were thus named "natural" killer cells, or NK cells. They are roughly defined by a lack of the T cell marker CD3 and a presence of CD56 (o...

journal_title：Immunology letters

authors： Ribatti D

更新日期：2017-10-01 00:00:00

abstract：:We describe the quantification of the absolute amounts of HLA class II mRNA and class II transactivator (CIITA) mRNA by competitive reverse transcription polymerase chain reaction in cultured synovial fibroblast-like cells (SFC) of patients with rheumatoid arthritis. High basal levels of transcription of class II mRNA...

journal_title：Immunology letters

authors： Navarrete Santos A,Riemann D,Thiele K,Kehlen A,Navarrete Santos A,Langner J

更新日期：1997-06-01 00:00:00

abstract：:Diabetes mellitus is associated with an increased incidence of cardiovascular events and microvascular complications. Serum amyloid A (SAA), a HDL apolipoprotein is a risk marker for cardiovascular disease. A permanent increase in SAA plasma levels is observed in diabetics. Because SAA acts on leukocytes, we evaluated...

journal_title：Immunology letters

authors： Hatanaka E,Monteagudo PT,Marrocos MS,Campa A

更新日期：2007-02-15 00:00:00

abstract：:Luminol-dependent chemiluminescence (CL) triggered by mineral dust in rabbit alveolar macrophages depended on superoxide production as revealed by inhibition by superoxide dismutase and ferricytochrome c. The contribution of superoxide changed in the course of CL peak between 80-20%. The effects of ferricytochrome c w...

journal_title：Immunology letters

authors： Wilhelm J,Vilím V,Brzák P

更新日期：1987-08-01 00:00:00

abstract：:Two types of inhibition of basic peptide-induced rat mast cell secretion are reported. Pretreatment of rat peritoneal mast cells with Vibrio comma neuraminidase, an enzyme which cleaves sialic acid from oligosaccharides, led to inhibition of 5-hydroxytryptamine release induced by the basic peptides polylysine, cortico...

journal_title：Immunology letters

authors： Coleman JW

更新日期：1982-10-01 00:00:00

abstract：:Psoriasis and psoriatic arthritis (PsA) are common diseases associated with considerable morbidity and disability. Their pathophysiology comprises a dysfunctional stromal-immune cell and cytokine network leading to inflammation of skin, entheses and joints. Recent advances in understanding of disease pathogenesis have...

journal_title：Immunology letters

authors： Hueber AJ,McInnes IB

更新日期：2007-12-15 00:00:00