Increased gamma delta T cells in acute Plasmodium falciparum malaria.

abstract：:Interleukin-18 (IL-18) gene promoter polymorphism is known as a genetic risk factor for child type 1 diabetes mellitus development. To test the role of IL-18 gene polymorphism in predisposition to adult type 1 diabetes (T1DM) and latent autoimmune diabetes in adults (LADA), we analysed SNPs at position -607 (C/A) and ...

journal_title：Immunology letters

authors： Novota P,Kolostova K,Pinterova D,Novak J,Treslova L,Andel M,Cerna M

更新日期：2005-01-31 00:00:00

abstract：:Vogt-Koyanagi-Harada disease is an autoimmune systemic disorder. In Vogt-Koyanagi-Harada disease, inflammatory disorders occur in multiple organs containing melanocytes, including uvea (resulting in acute bilateral panuveitis), skin (resulting in vitiligo and alopecia), central nervous system (resulting in meningitis)...

journal_title：Immunology letters

authors： Yamada K,Senju S,Shinohara T,Nakatsura T,Murata Y,Ishihara M,Nakamura S,Ohno S,Negi A,Nishimura Y

更新日期：2001-10-01 00:00:00

abstract：:The antischistosomal property of a short course of cyclosporin A (CsA), administered at the time of infection was demonstrated in the rat. In comparison with vehicle-treated controls, no schistosomes were recovered from CsA-treated animals, 18-19 days post infection. Flow cytometric analysis of blood and spleen lympho...

journal_title：Immunology letters

authors： Thomson AW,Chappell LH

更新日期：1988-02-01 00:00:00

abstract：:We describe the quantification of the absolute amounts of HLA class II mRNA and class II transactivator (CIITA) mRNA by competitive reverse transcription polymerase chain reaction in cultured synovial fibroblast-like cells (SFC) of patients with rheumatoid arthritis. High basal levels of transcription of class II mRNA...

journal_title：Immunology letters

authors： Navarrete Santos A,Riemann D,Thiele K,Kehlen A,Navarrete Santos A,Langner J

更新日期：1997-06-01 00:00:00

abstract：:Mast cells are important effector cells in IgE-associated immune responses, but also can contribute to host defense in certain examples of bacterial infection. We found that genetically mast cell-deficient WBB6F1-Kit(W)/Kit(W-v) mice exhibited more bacterial CFUs per spleen by 6 days after intraperitoneal injection of...

journal_title：Immunology letters

authors： Chatterjea D,Burns-Guydish SM,Sciuto TE,Dvorak A,Contag CH,Galli SJ

更新日期：2005-06-15 00:00:00

abstract：:The production of neutralizing antibodies against the central portion of HIV-1 gp120 requires cooperation between T cell and B cell epitopes of this region. We found a motif common to the carboxyterminus of the second conserved region of HIV-1 gp120 and sequences of some human proteins, most of which participate in im...

journal_title：Immunology letters

authors： Veljković V,Metlas R

更新日期：1990-11-01 00:00:00

abstract：:Control animals and rats infected 90 days earlier, by inoculation of 1 x 10(6) trypomastigotes of Trypanosoma cruzi at weaning, were subjected to adult thymectomy (ATx) or sham operation (S-ATx) and assessed 3 months later for the presence of myocardial lesions and levels of lymph node and spleen T-cell populations. C...

journal_title：Immunology letters

authors： Bottasso OA,Revelli SS,Dávila H,Valenti JL,Musso OC,Ferro ME,Romero-Piffiguer M,Morini JC

更新日期：1993-08-01 00:00:00

abstract：UNLABELLED:To study the pathogenic importance of the rheumatoid factor (RF) in rheumatoid arthritis (RA) and to identify genes differentially expressed in patients and healthy individuals, total RNA was isolated from peripheral blood mononuclear cells (PBMC) from eight RF-positive and six RF-negative RA patients, and s...

journal_title：Immunology letters

authors： Bovin LF,Rieneck K,Workman C,Nielsen H,Sørensen SF,Skjødt H,Florescu A,Brunak S,Bendtzen K

更新日期：2004-05-15 00:00:00

abstract：:Staphylococcus aureus (S. aureus) can often lead to many life-threatening diseases. It has the ability to invade normal endovascular tissue. Acute inflammation and its resolution are important to ensure bacterial clearance and limit tissue injury. Carbon monoxide (CO) has been shown to exert anti-inflammatory effects ...

journal_title：Immunology letters

authors： Tsai MH,Yang CM,Chang KT,Chuang CC,Lin WN,Jiang RS,Wu CH,Lee IT

更新日期：2018-11-01 00:00:00

abstract：:We infected umbilical cord blood lymphocytes (CBL) with EBV in vitro. Analysis of the cell population in 3- and 6-day-old cultures showed a relative increase of B cells and outgrowth of B cells after prolonged culture period. The immunomodulator PSK was added to parallel cultures. In these cultures, B cell growth was ...

journal_title：Immunology letters

authors： Liu A,Klein G,Bandobashi K,Klein E,Nagy N

更新日期：2002-03-01 00:00:00

abstract：:Administration of opioids that bind to the classical mu opioid receptor has been shown to lead to unintended alterations in immune function. Traditionally, altered immune function has been investigated with circulating immune cells. Effects of mu agonists on intestinal epithelial immune function have not been describe...

journal_title：Immunology letters

authors： Neudeck BL,Loeb JM

更新日期：2002-12-03 00:00:00

abstract：:Interleukin 18 (IL-18) gene polymorphisms have been reported to be associated with the outcomes of hepatitis C virus (HCV) infection in Americans, Indians and Europeans. We aimed to investigate whether the association can be replicated in Chinese Han population. Three IL-18 variants, -656G>T, -137G>C and +105A>C, were...

journal_title：Immunology letters

authors： Yue M,Wang JJ,Tang SD,Feng L,Zhang Y,Liu Y,Wang J,Deng XZ,Xu K,Zhang J

更新日期：2013-07-01 00:00:00

abstract：:We determined the degree of activation of the TNF alpha system and the levels of IL-8 in HIV-1 infection. TNF alpha is one of the most potent agents for the induction of IL-8. TNF alpha may be cleared rapidly from the circulation, however soluble tumor necrosis factor receptor (sTNFR) p75 which is more stable may refl...

journal_title：Immunology letters

authors： Hober D,Benyoucef S,Delannoy AS,De Groote D,Ajana F,Mouton Y,Wattré P

更新日期：1996-08-01 00:00:00

abstract：:Serum obtained from mice infected with Trypanosoma cruzi have antibodies able to induce immune lysis in presence of complement. Gel filtration in Sephadex G-200 and affinity chromatography with rabbit anti-mouse IgG and protein A-Sepharose showed that the antibodies responsible for the immune serum lytic activity are ...

journal_title：Immunology letters

authors： Stefani MM,Takehara HA,Mota I

更新日期：1983-01-01 00:00:00

abstract：:A theoretical analysis of experimental data is presented in this mini-review on non-random homo- and hetero-associations of cell surface receptors, which can be recruited in the plasma membrane or at the surface of the rough endoplasmic reticulum during the protein synthesis. In the latter case, the likely genetic ori...

journal_title：Immunology letters

authors： Damjanovich S,Mátyus L,Damjanovich L,Bene L,Jenei A,Matkó J,Gáspár R,Szöllösi J

更新日期：2002-06-03 00:00:00

abstract：:Aging is associated to dysfunctional changes in the immune system, a process termed immunosenescence. Elderly individuals usually present chronic low level inflammation, likely as the consequence of continued exposure to antigens combined with poor immune function, increases in production of pro-inflammatory cytokines...

journal_title：Immunology letters

authors： Campos C,Pera A,Lopez-Fernandez I,Alonso C,Tarazona R,Solana R

更新日期：2014-11-01 00:00:00

abstract：:Secondary lymphoid organs (SLO) are crucial structures for immune-surveillance and rapid immune responses allowing resident lymphocytes to encounter antigen-presenting cells that carry antigens from peripheral tissues. These structures develop during embryonic life through a tightly regulated process that involves int...

journal_title：Immunology letters

authors： Coles M,Veiga-Fernandes H

更新日期：2013-11-01 00:00:00

abstract：:Numerous studies have dealt with occurrence of dendritic cells in various nonlymphoid organs such as kidney, liver or heart, whereas lymphocyte patterns in these organs have not been analyzed in detail. In the present study, leukocytes were quantified as cells/mm2 in the perivascular, interstitial and parenchymal tiss...

journal_title：Immunology letters

authors： Holzinger C,Zuckermann A,Reinwald C,Imhof M,Schöllhammer A,Kramer G,Wolner E,Steiner G

更新日期：1996-11-01 00:00:00

abstract：:While the pathophysiology of burn injury is well established in young adults, the factors that contribute to pathogenesis and increased death in elderly burn patients are not defined. The purpose of this study is to determine the effects of burn injury on mesenteric lymph node (MLN) T cell responses in young and aged ...

journal_title：Immunology letters

authors： Choudhry MA,Plackett TP,Schilling EM,Faunce DE,Gamelli RL,Kovacs EJ

更新日期：2003-04-03 00:00:00

abstract：:Several recent studies have shown that the antigen receptors (mIgM and mIgD) on normal B cell surfaces are part of larger multimolecular complexes, as each is noncovalently coupled to at least two other proteins whose phosphorylation is inducible upon G protein activation. However, B cell receptor complexes appear to ...

journal_title：Immunology letters

authors： Chang CC,Alhasan S,Rosenspire AJ

更新日期：1992-05-01 00:00:00

abstract：:The aim of the present letter is to propose a rational nomenclature for the d-mannose-binding lectin from seeds of Artocarpus integrifolia. It is justified by the existing confusion in the literature concerning the trivial names used until now to designate the lectin and by the increasing interest in its biomedical ap...

journal_title：Immunology letters

authors： Pereira-da-Silva G,Roque-Barreira MC,Van Damme EJ

更新日期：2008-08-15 00:00:00

abstract：:Crohn's disease and ulcerative colitis, known together as inflammatory bowel disease (IBD), are severe autoimmune disorders now causing gut inflammation and ulceration, among other symptoms, in up to 1 in 250 people worldwide. Incidence and prevalence of IBD have been increasing dramatically over the past several deca...

journal_title：Immunology letters

authors： Huang H,Vangay P,McKinlay CE,Knights D

更新日期：2014-12-01 00:00:00

abstract：:Homogeneous IgG fractions were obtained by chromatography of the sera of patients with multiple sclerosis (MS) on Protein G-Sepharose under conditions that remove non-specifically bound proteins. These IgGs contained several chelated metals, the relative amount of which decreases in the order: Fe>or=Ca>Cu>or=Zn>or=Mg>...

journal_title：Immunology letters

authors： Polosukhina DI,Kanyshkova TG,Doronin BM,Tyshkevich OB,Buneva VN,Boiko AN,Gusev EI,Nevinsky GA,Favorova OO

更新日期：2006-02-28 00:00:00

abstract：:Dendritic cells (DCs) from cancer patients, as well as tumor-infiltrating DCs, are reported to have suppressed immunostimulatory capacity. One of the major problems in the clinical use of DCs for treating tumors is that the DCs must be autologous ones obtained from patients. Compared with normal DCs (nDCs), flow-cytom...

journal_title：Immunology letters

authors： Furumoto K,Mori A,Yamasaki S,Inoue N,Yang W,Nakau M,Yasuda S,Arii S,Imamura M

更新日期：2002-08-01 00:00:00

abstract：:The effect of ageing on thymocyte progenitors in the bone marrow was studied in an in vitro experimental model that permits T lymphocyte development. The model is based on co-culture of BM cells from young and old mice with lymphoid depleted fetal thymus explants. We applied different strategies of thymic colonization...

journal_title：Immunology letters

authors： Globerson A

更新日期：1994-06-01 00:00:00

abstract：:Pertussis, or whooping cough, has recently reemerged as a major public health threat despite high levels of vaccination. The development of a novel pertussis vaccine, especially an intranasal (i.n.) vaccine is undoubtedly necessary, and mucosal adjuvants have been explored to enhance the immune response. In the presen...

journal_title：Immunology letters

authors： Shi W,Kou Y,Jiang H,Gao F,Kong W,Su W,Xu F,Jiang C

更新日期：2018-06-01 00:00:00

abstract：:Natural levels of goat antiphosphorylethanolamine (anti-PE) antibodies decreased after injection of purified human C-reactive protein (CRP). The concentration of anti-CRP antibodies followed a continuous increment from non-detectable levels to a plateau at 80 days after first injection. ...

journal_title：Immunology letters

authors： Coll JM

更新日期：1988-05-01 00:00:00

abstract：:The ability of immune checkpoint inhibitors (ICIs) to reactivate the killing function of the immune system to tumor cells has led to long lasting immune response presenting highly promising clinical advances. Recently, immune checkpoint inhibitors related resistance due to the specialized tumor microenvironment has al...

journal_title：Immunology letters

authors： Li Y,Liu J,Gao L,Liu Y,Meng F,Li X,Qin FX

更新日期：2020-04-01 00:00:00

abstract：:The experimental infection of macaques with simian immunodeficiency virus (SIV) has provided strong evidence that it may be possible to develop a vaccine against AIDS. Live attenuated SIV vaccines have been found to confer the most potent protection against challenge with a variety of pathogenic viruses. This article ...

journal_title：Immunology letters

authors： Almond N,Stott J

更新日期：1999-03-01 00:00:00

abstract：:The monocytic cell line I937 was derived from U937 by sorting for cells with high expression of MHC class II molecules. Further analysis of these class II molecules revealed the presence of the HLA-DR3 subtype suggesting that the cell line was a potential candidate for testing antigen presentation to T cells restricte...

journal_title：Immunology letters

authors： Reischl IG,Pöllabauer EM,Peiritsch S,Schlager S,Gladstone P,Vooijs WC,Woisetschläger M,Mudde GC

更新日期：1996-01-01 00:00:00