Abstract:
:The aim of the present letter is to propose a rational nomenclature for the d-mannose-binding lectin from seeds of Artocarpus integrifolia. It is justified by the existing confusion in the literature concerning the trivial names used until now to designate the lectin and by the increasing interest in its biomedical applications, specially those concerning the immunomodulation activity exerted by the lectin, triggered by the recognition of glycoconjugates on the surface of cells of the innate immunity. The new nomenclature proposed for the lectin refers to both its origin and its specificity on sugar recognition.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Pereira-da-Silva G,Roque-Barreira MC,Van Damme EJdoi
10.1016/j.imlet.2008.06.002subject
Has Abstractpub_date
2008-08-15 00:00:00pages
114-5issue
1-2eissn
0165-2478issn
1879-0542pii
S0165-2478(08)00154-5journal_volume
119pub_type
信件abstract::This report describes an immunoradiometric assay for Plasmodium falciparum in infected blood, based on a cross-reacting monoclonal antibody (mAb) raised against P. berghei. In this assay, binding of the mAb to intact P. berghei parasites coated on microtiter plates is inhibited by solubilized P. falciparum infected re...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(85)90046-x
更新日期:1985-01-01 00:00:00
abstract::Type I Diabetes mellitus (DM1) is the effect of T cell dependent autoimmune destruction of insulin producing beta cells in the pancreas islet. T cells are activated in response to islet dominant autoantigens, the result being the development of DM1. Insulin is one of the islet autoantigens responsible for activation o...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/s0165-2478(00)00309-6
更新日期:2001-01-15 00:00:00
abstract::We have studied the autocrine regulation of essential expression of the intercellular adhesion molecule-1 (ICAM-1) on 8 transitional cell carcinoma (TCC) cell lines (histopathological grades 1-3). The constitutive expression of ICAM-1 was regulated by soluble factors in an autocrine fashion. These factors were produce...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(94)90182-1
更新日期:1994-05-01 00:00:00
abstract::Interleukin-18 (IL-18) gene promoter polymorphism is known as a genetic risk factor for child type 1 diabetes mellitus development. To test the role of IL-18 gene polymorphism in predisposition to adult type 1 diabetes (T1DM) and latent autoimmune diabetes in adults (LADA), we analysed SNPs at position -607 (C/A) and ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2004.08.016
更新日期:2005-01-31 00:00:00
abstract::Vogt-Koyanagi-Harada disease is an autoimmune systemic disorder. In Vogt-Koyanagi-Harada disease, inflammatory disorders occur in multiple organs containing melanocytes, including uvea (resulting in acute bilateral panuveitis), skin (resulting in vitiligo and alopecia), central nervous system (resulting in meningitis)...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/s0165-2478(01)00243-7
更新日期:2001-10-01 00:00:00
abstract::The effect of priming with various antigens on subsequent vaccination with the pneumococcal conjugate vaccine (CPV) was determined using BALB/c mice. Priming with pneumococcal polysaccharide or cross-reactive polysaccharide did not inhibit the IgG response to CPV immunization. Additionally, live intranasal colonizatio...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2006.04.013
更新日期:2006-08-15 00:00:00
abstract::Pertussis, or whooping cough, has recently reemerged as a major public health threat despite high levels of vaccination. The development of a novel pertussis vaccine, especially an intranasal (i.n.) vaccine is undoubtedly necessary, and mucosal adjuvants have been explored to enhance the immune response. In the presen...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2018.03.012
更新日期:2018-06-01 00:00:00
abstract::We have mapped a T cell epitope in the circumsporozoite (CS) protein of the murine malaria parasite, Plasmodium yoelii. A 21-mer synthetic peptide corresponding to the amino acid positions 59-79 (referred to as Py1), induced specific proliferation in BALB/c and C57BL/6 mice, and provided help for the production of ant...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(90)90092-5
更新日期:1990-08-01 00:00:00
abstract::In a previous study we have shown that, in response to electrical stimulation, there is a substantial release of noradrenaline (NA) from the sympathetic nerve terminals of the rat thymus which is of axonal, vesicular origin. In the present study neurochemical evidence was obtained that the release of NA is subject to ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(95)00085-j
更新日期:1995-07-01 00:00:00
abstract::We aimed to investigate if angiopoietin-2 (Ang-2) participates in the septic process and what may be the role of monocytes as a site of release of Ang-2 in sepsis. Concentrations of Ang-2 were estimated in sera and in supernatants of monocytes derived form one already described cohort of 90 patients with septic syndro...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2009.06.006
更新日期:2009-06-30 00:00:00
abstract::Tumor cells express a range of antigens including self-antigens (those whose expression is shared by normal host tissue) and non-self antigens (such as those that arise as a result of mutations in normal cellular genes or in the case of some tumors, viral antigens). Immune responses to both types of antigen have been ...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/s0165-2478(02)00240-7
更新日期:2003-01-22 00:00:00
abstract::In the H-2-incompatible donor-recipient combination (BALB/c----CBA/H) local administration of cyclosporin allows a 4-fold reduction in a single dose prolonging survival of heart tissue allografts. These results suggest that local administration of cyclosporin may be useful for certain grafts. ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(90)90067-z
更新日期:1990-02-01 00:00:00
abstract::As one studies more and more the immune systems of invertebrates their multiplicity and diversity increase. On one hand, the number of different local and systemic innate mechanisms (or cascades of mechanisms) increases with every phylum studied, on the other hand the diversity increases within each system as multiple...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/j.imlet.2003.10.012
更新日期:2004-03-29 00:00:00
abstract::Lck is the principal signal-generating tyrosine kinase of the T cell activation mechanism. We have previously demonstrated that induced Lck activation outside of lipid rafts (LR) results in the rapid translocation of a fraction of Lck to LR. While this translocation predicates the subsequent production of IL-2, the me...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2012.01.001
更新日期:2012-02-29 00:00:00
abstract::Psoriasis and psoriatic arthritis (PsA) are common diseases associated with considerable morbidity and disability. Their pathophysiology comprises a dysfunctional stromal-immune cell and cytokine network leading to inflammation of skin, entheses and joints. Recent advances in understanding of disease pathogenesis have...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/j.imlet.2007.08.009
更新日期:2007-12-15 00:00:00
abstract::Tuberculosis (TB) is a highly infectious disease and its early and precise diagnosis is essential to reduce morbidity and mortality of patients. Since the routine diagnostic tests (like Monteux, AFB smear microscopy, chest X-Ray) do not give infallible results, additional tests are always recommended. Therefore to add...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2019.03.010
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:Considering the role of interleukin (IL)-9 and IL-9-producing Th9 cells in pathogenesis of autoimmune diseases, this study aimed to evaluate serum IL-9 levels in patients with Behçet's disease (BD) compared to healthy subjects and to assess whether there is an association between serum IL-9 levels and dise...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2019.05.007
更新日期:2019-07-01 00:00:00
abstract::In studying terminal lytic events of sensitized erythrocytes which have reacted with all 9 components of complement, we agree in general with the conclusions of Boyle and Borsos [1] that the cellular intermediate passes through the stages E*bound, E*inserted, and E*doomed. However, we differ with these workers on the ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(81)90095-x
更新日期:1981-04-01 00:00:00
abstract::Nervous and immune systems share specific recognition molecules for signals that originate in both systems. The information substances are polypeptides and their receptors. They comprise the multi-directional information exchange network whereby brain and nervous system function including mood and emotion can be integ...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/0165-2478(87)90171-4
更新日期:1987-12-01 00:00:00
abstract::Melanoma is a prototype of immunogenic tumor to which various types of immunotherapy have been applied extensively over the past decades. Melanoma vaccines are designed for the purpose of immune modulation and subsequent anti-tumor effects in the process of an active specific immunotherapy. Previous attempts of these ...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/s0165-2478(00)00251-0
更新日期:2000-09-15 00:00:00
abstract::Transforming growth factor-beta (TGF-beta) is usually known as an immunosuppressive cytokine, but we and others have shown stimulatory effects of TGF-beta on activation of Th2 T-lymphocytes. In the present investigation we have studied the effect of TGF-beta1 on phosphorylation of ERK, a MAP-kinase downstream of the R...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/s0165-2478(00)00184-x
更新日期:2000-06-01 00:00:00
abstract::The effect of B cell depletion on the induction and severity of murine experimental autoimmune thyroiditis was investigated. Thirteen CBA mice were given repeated intraperitoneal doses of 700 micrograms purified rabbit anti-mouse Ig antibody from 24 hours to 8 weeks after birth. Controls were given normal rabbit IgG (...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(89)90063-1
更新日期:1989-01-15 00:00:00
abstract::During their differentiation, thymocytes are subjected to two rounds of selection. First, CD4-8- double-negative (DN) thymocytes with a functional TCR-beta chain express a alpha-beta+ CD3 complex on their surface and, as a consequence, are selected to mature to the CD4+8+ double-positive (DP) stage. This round ends af...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(94)00197-y
更新日期:1995-01-01 00:00:00
abstract::Domain deleted paraproteins are suitable tools to study the interaction between IgG domains and Fc receptor (FcR) binding sites. The effect of the C gamma 2 or C gamma 3 domain deleted paraproteins was compared on antibody dependent cellular cytotoxicity (ADCC) and on FcR mediated rosette formation. The C gamma 2 doma...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(86)90035-0
更新日期:1986-06-01 00:00:00
abstract::ITIM-bearing receptors, a family which only recently has been recognized, play a key role in the regulation of the ITAM-induced activation of immune competent cells. The mechanism of ITM-mediated regulation in various cells was recently clarified. The present review focuses on ITIM bearing membrane proteins that negat...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/s0165-2478(99)00024-3
更新日期:1999-05-03 00:00:00
abstract::CD24 is an extensively glycosylated membrane protein that is linked to the membrane via a glycosyl-phosphatidylinositol (GPI)-anchor. In mice, CD24 is expressed by hematopoietic and non-hematopoietic cells. CD24-/- mice do not have gross immunological defects, but detailed analysis revealed strongly reduced responses ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2014.06.004
更新日期:2014-09-01 00:00:00
abstract::Partially purified IgE receptor(s) of rat basophilic leukemia cells (RBL) designated R and H and having apparent molecular weight of 45,000 and 55,000 daltons, respectively, were subjected to proteolysis with papain. Polyacrylamide gel electrophoresis of the digests in the presence of sodium dodecyl sulfate revealed a...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(82)90029-3
更新日期:1982-03-01 00:00:00
abstract::The physiological role(s) of fetuin, a protein present in plasma and many tissues of developing animals at levels much higher than in the adult, is unknown. Here we show that fetuin can modify the responses of macrophages to lipopolysaccharide (LPS) stimulation. At concentrations of fetuin in the medium, corresponding...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/s0165-2478(97)00126-0
更新日期:1998-01-01 00:00:00
abstract::There is increasing evidence for the role of basophils in allergic bronchial asthma. We studied the potential role of basophils in the pathogenesis of post-exercise-induced bronchoconstriction by measuring the histamine release from basophils both spontaneously and following ConA, FMLP, anti-IgE and TPA treatment. Two...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(94)90026-4
更新日期:1994-09-01 00:00:00
abstract::Using micro-electrode technique we studied the effects of interleukin-2 (50 ng/ml) on bio-electric activity of rat atrial myocardium under normal conditions and after gradual stretching of the tissue. It was shown that interleukin-2 caused increasing in the duration of action potential at the levels of 25, 50, and 90%...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2015.06.009
更新日期:2015-09-01 00:00:00