Abstract：
BACKGROUND:Vitamin D (vitD) is involved in important regulatory functions of the innate and adaptive immune system. So, it has been hypothesized that vitD might influence the course of atopic dermatitis (AD). Also obesity may have impact on immune system. The aim of our study was to investigate vitamin D status and body mass index (BMI) in urban children with AD. METHODS:52 children with AD and 43 healthy children were enrolled. SCORAD, BMI and serum vitD levels were evaluated. RESULTS:There was an association between vitamin D and the AD occurrence but neither between vitamin D and the AD severity, nor between vitamin D and BMI. A positive correlation was observed between BMI and the AD severity in males. CONCLUSIONS:This study highlights the complex inter-relationships among atopic dermatitis severity, vitamin D and body mass index and suggests the need to investigate the role of genetic factors and/or gender-related differences to possibly identify new prevention strategies.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
D'Auria E,Barberi S,Cerri A,Boccardi D,Turati F,Sortino S,Banderali G,Ciprandi Gdoi
10.1016/j.imlet.2016.11.004subject
Has Abstractpub_date
2017-01-01 00:00:00pages
31-35eissn
0165-2478issn
1879-0542pii
S0165-2478(16)30266-8journal_volume
181pub_type
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