Abstract:
:Modulation of the IgE response by PHA treatment in relation to animal sex was analysed. Male and female RF mice were immunized with ovalbumin in aluminum hydroxide gel and PHA was injected 1 or 2 days before immunization. Castrated mice were also immunized and received PHA on day -2. The results show that the IgE response is lower in the male than in the female group. An opposite class specific modulation depending on the timing of the PHA inoculation is observed between males and females. This effect is not observed in castrated mice. IgM and/or IgG production is neither modified by sex nor by the mitogen treatment.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Astorquiza MI,Cisternas C,Leal Xdoi
10.1016/0165-2478(87)90056-3subject
Has Abstractpub_date
1987-10-01 00:00:00pages
27-30issue
1eissn
0165-2478issn
1879-0542pii
0165-2478(87)90056-3journal_volume
16pub_type
杂志文章abstract::Donor-reactive memory T cells mediated accelerated rejection is known as a barrier to the survival of transplanted organs. We investigated the combination of different monoclonal antibodies (mAbs) and donor-specific transfusion (DST) in memory T cells-based adoptive mice model. In the presence of donor-reactive memory...
journal_title:Immunology letters
pub_type: 杂志文章
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journal_title:Immunology letters
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pub_type: 历史文章,杂志文章,评审
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更新日期:2014-12-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
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更新日期:2000-11-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2005.12.002
更新日期:2006-05-15 00:00:00
abstract::A panel of synthetic peptides representing human lymphocyte antigen (HLA) B8, other class I and class II restricted T cell epitopes and two B cell epitopes, were all able to compete with recognition of a HLA B8 restricted epitope by a cytotoxic T cell clone. Competition was obtained when the competitor peptides were a...
journal_title:Immunology letters
pub_type: 杂志文章
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更新日期:1991-11-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(87)90157-x
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journal_title:Immunology letters
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2016.06.005
更新日期:2016-09-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2017.01.013
更新日期:2017-03-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2012.10.009
更新日期:2012-12-17 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(82)90084-0
更新日期:1982-07-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2006.04.013
更新日期:2006-08-15 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2016.04.011
更新日期:2016-06-01 00:00:00
abstract::Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. As such, it signals monocytes, macrophages and neutrophils to up-regulate phagocytic functions and to release pro-inflammatory cytokines. Despite the established role of CD14 as the main LPS receptor, the precise nature of t...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2004.07.019
更新日期:2005-01-15 00:00:00
abstract::Several studies have implicated a role for the cell surface glycoprotein CD44 in lymphocyte differentiation, adhesion to the matrix, homing, activation and apoptosis. However, the requirement of CD44 in B cell maturation remains elusive. To address this point, we analyzed the generation and activation of B lymphocytes...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2004.06.004
更新日期:2004-08-15 00:00:00
abstract::The inflammatory response plays an important role during the induction of several neonatal diseases. Previous studies have shown that during newborn infections, the natural imbalance between pro- and anti-inflammatory responses shifts toward the production of pro-inflammatory cytokines. In this study, we employed an a...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2015.12.004
更新日期:2016-02-01 00:00:00
abstract::As a cytokine adjuvant, granulocyte-macrophage colony-stimulating factor (GM-CSF) has been demonstrated to play central roles in the enhancement of the immune response and protection elicited by experimental vaccines. However, in our previous work, the co-administration of GM-CSF produced untoward effects on the immun...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2014.08.005
更新日期:2014-11-01 00:00:00
abstract::Interleukin 18 (IL-18) gene polymorphisms have been reported to be associated with the outcomes of hepatitis C virus (HCV) infection in Americans, Indians and Europeans. We aimed to investigate whether the association can be replicated in Chinese Han population. Three IL-18 variants, -656G>T, -137G>C and +105A>C, were...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2013.08.007
更新日期:2013-07-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(96)02519-9
更新日期:1996-04-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2013.09.026
更新日期:2013-11-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
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更新日期:2000-12-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
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更新日期:1999-03-15 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(88)90042-9
更新日期:1988-03-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/s0165-2478(96)02665-x
更新日期:1996-12-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/j.imlet.2013.02.005
更新日期:2013-03-01 00:00:00
abstract::The wide distribution of Borrelia burgdorferi, the spirochete causing Lyme borreliosis, represents a human health hazard in many areas of the world. Vaccination has been proposed as an effective prevention strategy. Vaccination experiments were conducted with preparations of recombinant outer surface protein A (OspA) ...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(94)90166-x
更新日期:1994-03-01 00:00:00
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journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/s0165-2478(02)00024-x
更新日期:2002-06-03 00:00:00
abstract:BACKGROUND:Notch pathway is highly conserved across species and is involved in the regulation of cell differentiation and activity both in embryonic development and adult life. Notch signaling has an important role in the development of hematopoietic stem cells and their differentiation to committed lineages, as well a...
journal_title:Immunology letters
pub_type: 杂志文章,评审
doi:10.1016/j.imlet.2020.04.010
更新日期:2020-07-01 00:00:00
abstract::The monocytic cell line I937 was derived from U937 by sorting for cells with high expression of MHC class II molecules. Further analysis of these class II molecules revealed the presence of the HLA-DR3 subtype suggesting that the cell line was a potential candidate for testing antigen presentation to T cells restricte...
journal_title:Immunology letters
pub_type: 杂志文章
doi:10.1016/0165-2478(95)02478-6
更新日期:1996-01-01 00:00:00