A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye.

abstract：:The enteric nervous system (ENS) of the larval moth Manduca sexta consists of two small ganglia and several nerve networks that lie superficially along the alimentary tract. Within this system are approximately 600 neurons that exhibit a spectrum of biochemical and morphological characteristics and that express these ...

journal_title：Developmental biology

authors： Copenhaver PF,Taghert PH

更新日期：1989-01-01 00:00:00

abstract：:The gastrointestinal (GI) tract of metazoans is lined by a series of regionally distinct epithelia. To maintain structure and function of the GI tract, regionally diversified differentiation of somatic stem cell (SC) lineages is critical. The adult Drosophila midgut provides an accessible model to study SC regulation ...

journal_title：Developmental biology

authors： Li H,Qi Y,Jasper H

更新日期：2016-11-15 00:00:00

abstract：:Soluble N-ethylmalameide-sensitive factor attachment protein receptor (SNARE) proteins are present in mammalian sperm and could be involved in critical membrane fusion events during fertilization, namely the acrosome reaction. Vesicle-associated membrane protein/synaptobrevin, a SNARE on the membrane of a vesicular ca...

journal_title：Developmental biology

authors： Ramalho-Santos J,Moreno RD,Sutovsky P,Chan AW,Hewitson L,Wessel GM,Simerly CR,Schatten G

更新日期：2000-07-01 00:00:00

abstract：:Monoclonal antibodies against the surface of embryonic osteogenic cells (SB-1, SB-2, SB-3, and SB-5) have been used to characterize the sequence of transitions involved in the osteogenic cell lineage. In the present study, immunohistochemical analyses of the expression of osteogenic cell surface antigens in organ cult...

journal_title：Developmental biology

authors： Bruder SP,Caplan AI

更新日期：1990-10-01 00:00:00

abstract：:An organism's genome sequence serves as a blueprint for the proteins and regulatory RNAs essential for cellular function. The genome also harbors cis-acting non-coding sequences that control gene expression and are essential to coordinate regulatory programs during embryonic development. However, the genome sequence i...

journal_title：Developmental biology

authors： Aday AW,Zhu LJ,Lakshmanan A,Wang J,Lawson ND

更新日期：2011-09-15 00:00:00

abstract：:Acute myeloid leukemia (AML) is a complex malignancy with poor prognosis. Several genetic lesions can lead to the disease. One of these corresponds to the NUP98-HOXA9 (NA9) translocation that fuses sequences encoding the N-terminal part of NUP98 to those encoding the DNA-binding domain of HOXA9. Despite several studie...

journal_title：Developmental biology

authors： Baril C,Gavory G,Bidla G,Knævelsrud H,Sauvageau G,Therrien M

更新日期：2017-01-01 00:00:00

abstract：:Concentration of mast-cell precursors in hematopoietic tissues of mouse embryos was evaluated by a limiting dilution method. Cells from yolk sacs, livers, and bodies of (WB x C57BL/6)F1 (hereafter called WBB6F1)- +/+ embryos were injected directly into the skin of adult WBB6F1-W/Wv mice which were genetically depleted...

journal_title：Developmental biology

authors： Sonoda T,Hayashi C,Kitamura Y

更新日期：1983-05-01 00:00:00

abstract：:Specification of the primordial germ cells (PGCs) is essential for sexually reproducing animals. Although the mechanisms of PGC specification are diverse between organisms, the RNA binding protein Nanos is consistently required in the germ line in all species tested. How Nanos is selectively expressed in the germ line...

journal_title：Developmental biology

authors： Oulhen N,Swartz SZ,Wang L,Wikramanayake A,Wessel GM

更新日期：2019-08-01 00:00:00

abstract：:The nematode gonad is an exemplary system for the study of organogenesis and fundamental problems in developmental and cellular biology. Nematode gonads vary dramatically across species (Chitwood, B.G., Chitwood, M.B., 1950. Introduction to Nematology." University Park Press, Baltimore; Felix, M.A., Sternberg, P.W., 1...

journal_title：Developmental biology

authors： Rudel D,Riebesell M,Sommer RJ

更新日期：2005-01-01 00:00:00

abstract：:During epithelial development cells become polarized along their apical-basal axis and some epithelia also exhibit polarity in the plane of the tissue. Mutations in the gene encoding a Drosophila Pak family serine/threonine kinase, dPak, disrupt the follicular epithelium that covers developing egg chambers during ooge...

journal_title：Developmental biology

authors： Conder R,Yu H,Zahedi B,Harden N

更新日期：2007-05-15 00:00:00

abstract：:Two distinct DNA ligases are expressed during early sea urchin embryogenesis. A light form (50 kDa) is found in unfertilized eggs (oocyte form) and a heavier enzyme (110 kDa) is observed at the two-cell stage (embryonic form). The chronology of the change reveals that the embryonic form is detected 90 min after fertil...

journal_title：Developmental biology

authors： Prigent C,Maniey D,Lefresne J,Epel D,Signoret J,David JC

更新日期：1987-11-01 00:00:00

abstract：:We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Polymorphism (SSLP) markers. Using a bioinformatics-based strategy, we identified unique SSLPs within the X. tropicalis genome. Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Simple Sequence Repeats (SSR...

journal_title：Developmental biology

authors： Wells DE,Gutierrez L,Xu Z,Krylov V,Macha J,Blankenburg KP,Hitchens M,Bellot LJ,Spivey M,Stemple DL,Kowis A,Ye Y,Pasternak S,Owen J,Tran T,Slavikova R,Tumova L,Tlapakova T,Seifertova E,Scherer SE,Sater AK

更新日期：2011-06-01 00:00:00

abstract：:The Toll signaling pathway functions in several Drosophila processes, including dorsal-ventral pattern formation and the immune response. Here, we demonstrate that this pathway is required in the epidermis for proper muscle development. Previously, we showed that the zygotic Toll protein is necessary for normal muscle...

journal_title：Developmental biology

authors： Halfon MS,Keshishian H

更新日期：1998-07-01 00:00:00

abstract：:Auxin is implicated throughout plant growth and development. Although the effects of this plant hormone have been recognized for more than a century, it is only in the past two decades that light has been shed on the molecular mechanisms that regulate auxin homeostasis, signaling, transport, crosstalk with other hormo...

journal_title：Developmental biology

authors： Finet C,Jaillais Y

更新日期：2012-09-01 00:00:00

abstract：:A cDNA of the sea urchin Strongylocentrotus purpuratus was identified as encoding polyubiquitin and used to detect a single gene with transcripts containing multiple ubiquitin coding units. Polyubiquitin transcripts exist as a 3.2-kb RNA in polyribosomes and as three higher molecular weight RNAs in purified nuclei. Th...

journal_title：Developmental biology

authors： Nemer M,Rondinelli E,Infante D,Infante AA

更新日期：1991-06-01 00:00:00

abstract：:Dorsoventral specification of the zebrafish gastrula is governed by the functions of the dorsal shield, a region of the embryo functionally analogous to the amphibian Spemann organizer. We report that the bozozok locus encodes the transcription factor nieuwkoid/dharma, a homeobox gene with non-cell-autonomous organize...

journal_title：Developmental biology

authors： Koos DS,Ho RK

更新日期：1999-11-15 00:00:00

abstract：:The specification of the five individual hormone-secreting cell types in the anterior pituitary requires a series of sequential cell fate decisions. We have immortalized cells at several stages along this pathway of pituitary differentiation. Here, we present analysis of differences in gene expression between an anter...

journal_title：Developmental biology

authors： Holley SJ,Hall SB,Mellon PL

更新日期：2002-04-15 00:00:00

abstract：:Successful fertilization requires that sperm are activated prior to contacting an oocyte. In C. elegans, this activation process, called spermiogenesis, transforms round immobile spermatids into motile, fertilization-competent spermatozoa. We describe the phenotypic and genetic characterization of spe-43, a new compon...

journal_title：Developmental biology

authors： Krauchunas AR,Mendez E,Ni JZ,Druzhinina M,Mulia A,Parry J,Gu SG,Stanfield GM,Singson A

更新日期：2018-04-15 00:00:00

abstract：:Temperature sex determining species offer a model for investigating how environmental cues become integrated to the regulation of patterning genes and growth, among bipotential gonads. Manipulation of steroid hormones has revealed the important role of aromatase in the regulation of the estrogen levels involved in tem...

journal_title：Developmental biology

authors： Díaz-Hernández V,Marmolejo-Valencia A,Merchant-Larios H

更新日期：2015-12-01 00:00:00

abstract：:The GRAM domain was found in glucosyltransferases, myotubularins and other membrane-associated proteins. So far, functions for majority of these proteins are yet to be uncovered. In order to address the evolutionary and functional significance of this family members, we have performed a comprehensive investigation on ...

journal_title：Developmental biology

authors： Jiang SY,Ramamoorthy R,Ramachandran S

更新日期：2008-02-15 00:00:00

abstract：:Aurora A is a mitotic kinase essential for cell proliferation. In mice, ablation of Aurora A results in mitotic arrest and pre-implantation lethality, preventing studies at later stages of development. Here we report the effects of Aurora A ablation on embryo patterning at early post-implantation stages. Inactivation ...

journal_title：Developmental biology

authors： Yoon Y,Cowley DO,Gallant J,Jones SN,Van Dyke T,Rivera-Pérez JA

更新日期：2012-11-01 00:00:00

abstract：:Microtubule organization during the novel cell division of ameiotic microsporocytes was examined using indirect immunofluorescence microscopy. A recessive mutation of the maize gene Ameiotic causes the replacement of meiosis I with a synchronized mitotic division (Palmer, R. G. (1971). Chromosoma 35, 233-246). All ide...

journal_title：Developmental biology

authors： Staiger CJ,Cande WZ

更新日期：1992-11-01 00:00:00

abstract：:DNA amplification for two major DNA puffs (II/2B and II/9A) of the fungus fly Sciara coprophila increases steeply from 17 to 19 days after hatching (18 degrees C), resulting in almost 20-fold more DNA at these loci in mature larval salivary glands than in adult tissues. At 19 days after hatching when gene amplificatio...

journal_title：Developmental biology

authors： Wu N,Liang C,DiBartolomeis SM,Smith HS,Gerbi SA

更新日期：1993-11-01 00:00:00

abstract：:Eph receptors play important roles in axon guidance at the midline. In the auditory system, growth of axons across the midline is an important determinant of auditory function. The avian cochlear nucleus, n. magnocellularis (NM), makes bilateral projections to its target, n. laminaris (NL). We examined the time course...

journal_title：Developmental biology

authors： Cramer KS,Cerretti DP,Siddiqui SA

更新日期：2006-07-01 00:00:00

abstract：:Projection neurons of the developing cerebral cortex are generated in the cerebral ventricular zone and subsequently move to the developing cortical plate via radial migration. Conversely, most inhibitory interneurons originate in the ganglionic eminences and enter the developing cortical plate by tangential migration...

journal_title：Developmental biology

authors： Britanova O,Alifragis P,Junek S,Jones K,Gruss P,Tarabykin V

更新日期：2006-10-01 00:00:00

abstract：:One rapid response of starfish oocytes to the maturation-inducing hormone, 1-methyladenine (1-MA), is the formation of transient actin-filled spikes on the cell surface. The presence and distribution of G- and F-actin and several actin-associated proteins were examined in cortices isolated from oocytes before, during,...

journal_title：Developmental biology

authors： Otto JJ,Schroeder TE

更新日期：1984-02-01 00:00:00

abstract：:We present evidence to show that differentiation in wing cells to produce hairs is synchronous over the distal 90% of the wing surface (approximately 28,000 cells). In spite of this synchrony within such a large area a temporal gradient exists between zones (in general anterior to posterior) on the animal surface with...

journal_title：Developmental biology

authors： Mitchell HK,Petersen NS

更新日期：1983-02-01 00:00:00

abstract：:Initiation of transcription mediated by RNA polymerase II requires a number of transcription factors among which TFIID is the major core promoter recognition factor. TFIID is composed of highly conserved factors which include the TATA-binding protein (TBP) and about 14 TBP-associated factors (TAFs). Recently, the comp...

journal_title：Developmental biology

authors： Lago C,Clerici E,Dreni L,Horlow C,Caporali E,Colombo L,Kater MM

更新日期：2005-09-01 00:00:00

abstract：:Hox genes are crucial players in the generation and pattering of the vertebrate trunk and posterior body during embryogenesis. Their initial expression takes place shortly after the establishment of the primitive streak, in the posterior-most part of the mouse embryo and is a determinant step for setting up the defini...

journal_title：Developmental biology

authors： Neijts R,Deschamps J

更新日期：2017-08-15 00:00:00

abstract：:MicroRNA attenuation of protein translation has emerged as an important regulator of mesenchymal cell differentiation into the osteoblast lineage. A compelling question is the extent to which miR biogenesis is obligatory for bone formation. Here we show conditional deletion of the Dicer enzyme in osteoprogenitors by C...

journal_title：Developmental biology

authors： Gaur T,Hussain S,Mudhasani R,Parulkar I,Colby JL,Frederick D,Kream BE,van Wijnen AJ,Stein JL,Stein GS,Jones SN,Lian JB

更新日期：2010-04-01 00:00:00