Abstract：
:A cDNA of the sea urchin Strongylocentrotus purpuratus was identified as encoding polyubiquitin and used to detect a single gene with transcripts containing multiple ubiquitin coding units. Polyubiquitin transcripts exist as a 3.2-kb RNA in polyribosomes and as three higher molecular weight RNAs in purified nuclei. The amount of polyubiquitin RNA is essentially constant at 10(4) -10(5) transcripts per embryo during the egg-to-blastula period and then declines during further development. Heat shock elicits a transient increase in the level of polyubiquitin RNA, while Zn(II) ions induce a sustained accumulation, that is influenced by developmental parameters: One round of Zn(II) induction elicits the accumulation of the nuclear 7.6- and 5.6-kb RNAs, as well as the 3.2-kb polysomal RNA; however, a second round of induction yields only the 5.6- and 3.2-kb RNAs, suggestive of a change in pre-mRNA size or processing. Polyubiquitin RNA is expressed equally in ectodermal and mesoendodermal tissues and is induced in both tissue fractions by treatment of pluteus larvae with Zn(II). However, in isolated and cultured tissue fractions, polyubiquitin RNA is not inducible by Zn(II), in contrast to the full inducibility of metallothionein mRNAs. Polyubiquitin RNA induction thus appears to be conditioned by the integrity of the embryo, as well as by previous exposure to inducer.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Nemer M,Rondinelli E,Infante D,Infante AAdoi
10.1016/0012-1606(91)90124-lsubject
Has Abstractpub_date
1991-06-01 00:00:00pages
255-65issue
2eissn
0012-1606issn
1095-564Xpii
0012-1606(91)90124-Ljournal_volume
145pub_type
杂志文章abstract：:An increase in the incidence of aneuploidy is well documented with increasing maternal age, in particular in human females. Remarkably, little is known regarding the underlying molecular basis for the age-associated increase in aneuploidy, which is a major source of decreased fertility in humans. Using mouse as a mode...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.01.048
更新日期：2008-04-15 00:00:00
abstract：:Copyright ...
journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(87)90235-1
更新日期：1987-04-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.0096
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abstract：:We demonstrate that interspecific sequence conservation can provide a systematic guide to the identification of functional cis-regulatory elements within a large expanse of genomic DNA. The test was carried out on the otx gene of Strongylocentrotus purpuratus. This gene plays a major role in the gene regulatory networ...
journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(91)90313-r
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(90)90372-p
更新日期：1990-12-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.8045
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1993.1176
更新日期：1993-07-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2007-07-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2010-03-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.1104
更新日期：1995-04-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2004.05.034
更新日期：2004-09-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2005.07.025
更新日期：2005-10-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.2000.0145
更新日期：2001-03-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2007.10.048
更新日期：2008-01-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(91)90435-6
更新日期：1991-04-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2006.09.021
更新日期：2007-02-01 00:00:00
abstract：:The developing chick limb bud contains several stage-specific populations of muscle colony-forming (MCF) cells. The cell lineage relationships of these populations are not completely understood, but previous studies have suggested that there may be at least two myogenic precursor populations present in the limb bud. T...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(84)90237-9
更新日期：1984-12-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2019-04-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2001-03-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(90)90149-d
更新日期：1990-11-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.2000.9970
更新日期：2001-01-01 00:00:00
abstract：:Temporally-regulated maternal RNA translation is essential for embryonic development, with defective degradation resulting in stalled 2-cell embryos. We show that DDX1, a DEAD box protein implicated in RNA transport, may be a key regulator of maternal RNA utilization. DDX1 protein localizes exclusively to cytoplasmic ...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2019-11-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(91)90286-c
更新日期：1991-10-01 00:00:00
abstract：:In Hydra long-range interactions between head, bud, and foot formation take place in addition to short-range interactions which are recognized as induction phenomena, occurring when transplants are placed into an environment of disparate positional value. Here the long-range promotion of foot formation is analyzed. Th...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1995-01-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2007-05-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.0321
更新日期：1996-12-15 00:00:00
abstract：:Pericytes heterogeneity is based on their morphology, distribution, and markers. It is well known that pericytes from different organs may have distinct embryonic sources. Yamazaki et al. (2017) using several transgenic mouse model reveal by cell-lineage tracing that pericytes are even more heterogeneous than previous...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2017-07-01 00:00:00
abstract：:This paper reports a preliminary in silico analysis of the sea urchin kinome. The predicted protein kinases in the sea urchin genome were identified, annotated and classified, according to both function and kinase domain taxonomy. The results show that the sea urchin kinome, consisting of 353 protein kinases, is close...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2006.08.074
更新日期：2006-12-01 00:00:00
