Toward the molecular flashlight: preparation, properties, and photophysics of a hypericin-luciferin tethered molecule.

abstract：:2-Aminoacetophenone (AAP) was recognized as the key compound for the so-called untypical aging off-flavor (UTA) in Vitis vinifera wines. In this study, it was shown that AAP can be formed by photooxidation of free and protein-bound tryptophan (TRP) in combination with a subsequent storage in model wine. Solutions of T...

journal_title：Photochemistry and photobiology

authors： Horlacher N,Schwack W

更新日期：2014-11-01 00:00:00

abstract：:Generating accurate population-specific public health messages regarding sun protection requires knowledge about seasonal variation in sun exposure in different environments. To address this issue for a subtropical area of Australia, we used polysulphone badges to measure UVR for the township of Nambour (26 degrees la...

journal_title：Photochemistry and photobiology

authors： Neale RE,Hamilton AR,Janda M,Gies P,Green AC

更新日期：2010-03-01 00:00:00

abstract：:The total ozone column (TOC) is the most significant quantity for estimating the erythemally effective UV radiation under clear sky conditions. Uncertainties in TOC measurements and a limited spatial and temporal resolution therefore influence the quality of calculated erythemally effective radiation. The UV Index, th...

journal_title：Photochemistry and photobiology

authors： Schmalwieser AW,Erbertseder T,Schauberger G,Weihs P

更新日期：2008-09-01 00:00:00

abstract：:The objective of the present study was to investigate the treatment of 9L gliosarcoma brain tumor in the rat with the combination of surgical resection and photodynamic therapy (PDT). Nude rats with intracranial 7-day-old 9L gliomas were randomly subjected to no treatment, PDT alone (Photofrin: 2 mg kg(-1), optical: 8...

journal_title：Photochemistry and photobiology

authors： Zhang X,Jiang F,Kalkanis SN,Yang H,Zhang Z,Katakowski M,Hong X,Zheng X,Chopp M

更新日期：2006-11-01 00:00:00

abstract：:The fluoroquinolone (FQ) antibiotics photosensitize human skin to solar UV radiation and are reported to photosensitize tumor formation in mouse skin. As tumor initiation will not occur without genotoxic insult, we examined the potential of ciprofloxacin, lomefloxacin, fleroxacin, BAYy3118 (a recently developed monofl...

journal_title：Photochemistry and photobiology

authors： Reavy HJ,Traynor NJ,Gibbs NK

更新日期：1997-09-01 00:00:00

abstract：:G protein-coupled receptors (GPCRs) are involved in the control of virtually all aspects of our behavior and physiology. Activated receptors catalyze nucleotide exchange in heterotrimeric G proteins (composed of alpha.GDP, beta and gamma subunits) on the inner surface of the cell membrane. The GPCR rhodopsin and the G...

journal_title：Photochemistry and photobiology

authors： Chen Y,Herrmann R,Fishkin N,Henklein P,Nakanishi K,Ernst OP

更新日期：2008-07-01 00:00:00

abstract：:Photoreduction of cytochrome c (Cyt c) has been reinvestigated using femtosecond-to-nanosecond transient absorption and stationary spectroscopy. Femtosecond spectra of oxidized Cyt c, recorded in the probe range 270-1000 nm, demonstrate similar evolution upon 266 or 403 nm excitation: an ultrafast 0.3 ps internal conv...

journal_title：Photochemistry and photobiology

authors： Löwenich D,Kleinermanns K,Karunakaran V,Kovalenko SA

更新日期：2008-01-01 00:00:00

abstract：:Types of photoreceptor cells in the retinas of 36 species of vertebrates (5 classes, 14 orders) were investigated immunocytochemically with monoclonal antibodies against chicken iodopsin (Io-mAb) and antiserum against bovine rhodopsin (Rh-As). In mammals, Rh-As labeled the outer segments of some photoreceptor cells in...

journal_title：Photochemistry and photobiology

authors： Kawata A,Oishi T,Fukada Y,Shichida Y,Yoshizawa T

更新日期：1992-12-01 00:00:00

abstract：:The activity of the bimodal fluorescent protein (bmFP) (lambda max, 488 and 517 nm) in the in vitro luciferase reaction has been studied. The bmFP that is produced by Photobacterium phosphoreum strain bmFP is a dimer of two homologous subunits binding four riboflavin 5'-phosphate (FMN)-myristate chromophores. The addi...

journal_title：Photochemistry and photobiology

authors： Karatani H,Konaka T

更新日期：2000-02-01 00:00:00

abstract：:We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated...

journal_title：Photochemistry and photobiology

authors： Andreoni A,Colasanti A,Kisslinger A,Mastrocinque M,Portella G,Riccio P,Roberti G

更新日期：1993-05-01 00:00:00

abstract：:Photoproducts in double-stranded DNA induced by 193 nm radiation have been investigated. Double-stranded, supercoiled pBR322 DNA in buffered aqueous solution was exposed to varying fluences of 193 nm radiation from an ArF excimer laser. The quantum yields for formation of cyclobutylpyrimidine dimers, frank strand brea...

journal_title：Photochemistry and photobiology

authors： Kochevar IE,Buckley LA

更新日期：1990-05-01 00:00:00

abstract：:A new type of photochromic molecule that can be used for diffusion coefficient (D) measurements of various proteins in solution is described. The absorption spectrum of this molecule is changed upon photoexcitation by the trans-cis isomerization reaction. Target proteins were labeled by this photochromic molecule in t...

journal_title：Photochemistry and photobiology

authors： Eitoku T,Terazima M

更新日期：2008-07-01 00:00:00

abstract：:Photosensitized inhibition of mitochondrial succinoxidase by hypericin was measured in vitro and found to be drug-dose, light-dose, and wavelength dependent. Singlet oxygen generation, monitored using the singlet oxygen trap tetramethylethylene, and oxygen consumption in isolated mitochondria sensitized by hypericin w...

journal_title：Photochemistry and photobiology

authors： Thomas C,MacGill RS,Miller GC,Pardini RS

更新日期：1992-01-01 00:00:00

abstract：:After 50 years of studies on photobiomodulation (PBM), there is still so much to investigate to understand the laser light-nonplant cells interactions. The current scientific knowledge allows to say that the phenomena induced by PBM are based on cellular pathways that are the key points of cell life. The mitochondria ...

journal_title：Photochemistry and photobiology

authors： Amaroli A,Ferrando S,Benedicenti S

更新日期：2019-01-01 00:00:00

abstract：:UV-induced toxicity is characterized by marked oxidative stress, accompanied by the depletion of key cellular antioxidants, particularly glutathione (GSH). Replenishing cellular GSH may represent a means of counteracting UV-induced toxicity: however, treatment with free GSH is not therapeutically effective due to its ...

journal_title：Photochemistry and photobiology

authors： Wright D,Zampagni M,Evangelisti E,Conti S,D'Adamio G,Goti A,Becatti M,Fiorillo C,Taddei N,Cecchi C,Liguri G

更新日期：2013-03-01 00:00:00

abstract：:Direct irradiation of estrone aryl and methyl sulfonates in different organic solvents under nitrogen atmosphere was investigated under steady-state conditions. The estrone derivatives reacted efficiently through the photo-Fries rearrangement reaction involving [1;3]-sulfonyl migration providing the ortho-sulfonyl est...

journal_title：Photochemistry and photobiology

authors： Quindt MI,Gola GF,Ramirez JA,Bonesi SM

更新日期：2021-01-01 00:00:00

abstract：:The intrinsic autofluorescence properties of biological tissues can be affected by the occurrence of histological and biochemical alterations induced by pathological processes. In this study the potential of autofluorescence to distinguish tumor from normal tissues was investigated with the view of a real-time diagnos...

journal_title：Photochemistry and photobiology

authors： Croce AC,Fiorani S,Locatelli D,Nano R,Ceroni M,Tancioni F,Giombelli E,Benericetti E,Bottiroli G

更新日期：2003-03-01 00:00:00

abstract：:A novel type of circadian and photoperiodic control of the cell division cycle was found in photoautotrophic Euglena gracilis. When algae entrained to 24 h light-dark (LD) cycles (14 h L) were transferred to continuous darkness (DD) at the eighth hour of the final LD photoperiod, cell-cycle transition was arrested in ...

journal_title：Photochemistry and photobiology

authors： Hagiwara SY,Bolige A,Zhang Y,Takahashi M,Yamagishi A,Goto K

更新日期：2002-07-01 00:00:00

abstract：:The binding interactions of three naphthalimide derivatives with heteropoly nucleic acids have been evaluated using fluorescence, absorption and circular dichroism spectroscopies. Mono- and bifunctionalized naphthalimides exhibit sequence-dependent variations in their affinity toward DNA. The heteropoly nucleic acids,...

journal_title：Photochemistry and photobiology

authors： McMasters S,Kelly LA

更新日期：2007-07-01 00:00:00

abstract：:Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-UCA formation, the interaction of UCA isomers with DNA, the effects of...

journal_title：Photochemistry and photobiology

authors： Norval M,Gibbs NK,Gilmour J

更新日期：1995-08-01 00:00:00

abstract：:The azide ion is a strong physical quencher of singlet molecular oxygen (1O2) and is frequently employed to show involvement of 1O2 in oxidation processes. Rate constants (k(q)) for the quenching of 1O2 by azide are routinely used as standards to calculate k(q) values for quenching by other substrates. We have measure...

journal_title：Photochemistry and photobiology

authors： Li MY,Cline CS,Koker EB,Carmichael HH,Chignell CF,Bilski P

更新日期：2001-12-01 00:00:00

abstract：:Photodynamic therapy (PDT) appears as a promising alternative in the treatment of breast cancer since it can be highly effective in curing cancer while preserving normal tissue. However, predicting outcomes in PDT still constitutes a great challenge. One of the parameters that are usually empirically determined is the...

journal_title：Photochemistry and photobiology

authors： Dos Santos AF,de Almeida DRQ,Terra LF,Wailemann RAM,Gomes VM,Arini GS,Ravagnani FG,Baptista MS,Labriola L

更新日期：2020-05-01 00:00:00

abstract：:This paper studies the dye-sensitized photooxidation of tyrosine (tyr) and tyr di- and tripeptides (tyr-tyr and tyr-tyr-tyr) mediated by singlet molecular oxygen (O2[1 delta g]) in alkaline media. Photooxidation quantum efficiencies (phi r) were obtained by determining the overall and reactive rate constants of intera...

journal_title：Photochemistry and photobiology

authors： Criado S,Soltermann AT,Marioli JM,García NA

更新日期：1998-10-01 00:00:00

abstract：:Under continuous photolysis at 675 nm, liposomal zinc phthalocyanine associated with nitrosyl ruthenium complex [Ru(NH.NHq)(tpy)NO](3+) showed the detection and quantification of nitric oxide (NO) and singlet oxygen ((1)O(2)) release. Photophysical and photochemical results demonstrated that the interaction between th...

journal_title：Photochemistry and photobiology

authors： Maranho DS,de Lima RG,Primo FL,da Silva RS,Tedesco AC

更新日期：2009-05-01 00:00:00

abstract：:The energetic characteristics of selected reaction steps in the bacterial luciferase-catalyzed luminescence reaction were examined by computation using the MNDO-PM3 method. Specifically, a three-step model was proposed to account for the reaction between oxygen and reduced riboflavin 5'-phosphate (1,5H2-FMN) to genera...

journal_title：Photochemistry and photobiology

authors： Wada N,Sugimoto T,Watanabe H,Tu SC

更新日期：1999-07-01 00:00:00

abstract：:The proton channels of the bacteriorhodopsin (BR) proton pump contain bound water molecules. The channels connect the purple membrane surfaces with the protonated retinal Schiff base at the membrane center. Films of purple membrane equilibrated at low relative humidity display a shift of the 570 nm retinal absorbance ...

journal_title：Photochemistry and photobiology

authors： Renthal R,Gracia N,Regalado R

更新日期：2000-11-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:In this study, we investigated whether the spectrum of p53 mutations in skin tumors induced in hairless SKH-hr1 mice by a solar simulator (290-400 nm) are similar to those found in skin tumors induced in C3H mice by UV radiation from unfiltered (250-400 nm) and Kodacel-filtered (290-400 nm) FS40 sunlamps. Analysis of ...

journal_title：Photochemistry and photobiology

authors： Ananthaswamy HN,Fourtanier A,Evans RL,Tison S,Medaisko C,Ullrich SE,Kripke ML

更新日期：1998-02-01 00:00:00

abstract：:The photophysical properties of 1,1'-diethyl-4,4'-carbocyanine chloride (kryptocyanine) have been measured in methanol solution and for the dye bound to human serum albumin, incorporated in neutral micelles and after incubation with leukemia cells. In all cases, it is found that formation of the triplet state of the d...

journal_title：Photochemistry and photobiology

authors： Harriman A,Luengo G,Gulliya KS

更新日期：1990-10-01 00:00:00

abstract：:The contribution of DNA strand breaks accumulating in the course of nucleotide excision repair to upregulation of the p53 tumor suppressor protein was investigated in human dermal fibroblast strains after treatment with 254 nm ultraviolet (UV) light. For this purpose, fibroblast cultures were exposed to UV and incubat...

journal_title：Photochemistry and photobiology

authors： Enns L,Murray D,Mirzayans R

更新日期：2000-10-01 00:00:00