In vitro photodynamic activity of kryptocyanine.

abstract：:Raman spectroscopy (RS) has potential for disease classification within the gastrointestinal tract (GI). A near-infrared (NIR) fiber-optic RS system has been developed previously. This study reports the first in vivo Raman spectra of human gastrointestinal tissues measured during routine clinical endoscopy. This was a...

journal_title：Photochemistry and photobiology

authors： Shim MG,Song LM,Marcon NE,Wilson BC

更新日期：2000-07-01 00:00:00

abstract：:In cultured human keratinocytes, the tumor suppressor p53 acts as a control element in the protective response to UVB radiation and is affected by a variety of factors linked to cellular adhesion and differentiation. Because keratinocytes within the epidermis are not a homogeneous population but differ in their prolif...

journal_title：Photochemistry and photobiology

authors： Will K,Neben M,Schmidt-Rose T,Deppert W,Wittern KP,Bergemann J

更新日期：2000-03-01 00:00:00

abstract：:Efficacy of ionizing radiation (I/R) was compared with phototoxic effects of photodynamic therapy (PDT) in vitro using two cell lines derived from patients with head and neck squamous cell carcinoma (HNSCC). A cell line derived from a donor with a human papilloma virus (HPV) infection was more responsive to I/R but si...

journal_title：Photochemistry and photobiology

authors： Kessel D,Cho WJ,Rakowski J,Kim HE,Kim HC

更新日期：2020-05-01 00:00:00

abstract：:An approximate formula for the UV Index (UVI) under cloud-free, unpolluted, low surface albedo conditions is: UVI approximately 12.5mu(o)(2.42)(Omega/300)(-1.23) where mu(o) is the cosine of the solar zenith angle and Omega is the total vertical ozone column (in Dobson Units, DU). The dependence on mu(o) and Omega is ...

journal_title：Photochemistry and photobiology

authors： Madronich S

更新日期：2007-11-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation, which triggers a wide range of cellular responses involved in photomorphogenesis and photoprotection. Two recent crystal structures of ...

journal_title：Photochemistry and photobiology

authors： Yang X,Montano S,Ren Z

更新日期：2015-09-01 00:00:00

abstract：:UV light leads to release of different secretory factors from irradiated cells of which some of them have been characterized. We have reported earlier that cells exposed to the supernatant medium from irradiated cells were resistant to killing by some genotoxic agents. In this study, we present our finding that demons...

journal_title：Photochemistry and photobiology

authors： Ghosh R,Guha D,Bhowmik S

更新日期：2012-05-01 00:00:00

abstract：:The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

journal_title：Photochemistry and photobiology

authors： Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

更新日期：1993-11-01 00:00:00

abstract：:The incidence of skin cancer is increasing rapidly, particularly in the Caucasian population. Epidemiological and experimental studies demonstrated that ultraviolet radiation (UVR) is the primary cause for the increasing incidence of skin cancer. It is well known that UV irradiation induces DNA damage. If the damage i...

journal_title：Photochemistry and photobiology

authors： Bush JA,Ho VC,Mitchell DL,Tron VA,Li G

更新日期：1999-09-01 00:00:00

abstract：:We previously reported that Shewanella oneidensis MR-1 is extremely sensitive to natural solar radiation (NSR). Here we analyzed the global transcriptional profile of MR-1 during a 1-h recovering period after exposure to ambient solar light at a dose that yields about 20% survival rate on a Luria-Bertani (LB) plate. W...

journal_title：Photochemistry and photobiology

authors： Qiu X,Tiedje JM,Sundin GW

更新日期：2005-11-01 00:00:00

abstract：:A new water-soluble porphyrin derivative, 2,4-bis(1-decyloxyethyl)-deuteroporphyrinyl-6,7-bisaspart ic acid (C10-DP), and its metal complexes (Ga, I(n), Zn, Mn, Cu, Ni and Fe) were examined for their physicochemical properties (absorption, fluorescence, triplet lifetime and partition coefficient) and photocytotoxicity...

journal_title：Photochemistry and photobiology

authors： Ando T,Irie K,Koshimizu K,Takemura T,Nishino H,Iwashima A,Takeda N,Nakajima S,Sakata I

更新日期：1993-04-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:UV-induced toxicity is characterized by marked oxidative stress, accompanied by the depletion of key cellular antioxidants, particularly glutathione (GSH). Replenishing cellular GSH may represent a means of counteracting UV-induced toxicity: however, treatment with free GSH is not therapeutically effective due to its ...

journal_title：Photochemistry and photobiology

authors： Wright D,Zampagni M,Evangelisti E,Conti S,D'Adamio G,Goti A,Becatti M,Fiorillo C,Taddei N,Cecchi C,Liguri G

更新日期：2013-03-01 00:00:00

abstract：:We study the fluorescence lifetime of the well-known 1-pyrene butyric acid (PBA) to assess oxygen concentrations in living cells. The behavior of the probe is first studied in water, ethanol, protein solution and liposome suspension. The Stern-Volmer plot of these solutions is linear, and the bimolecular reaction rate...

journal_title：Photochemistry and photobiology

authors： Ribou AC,Vigo J,Salmon JM

更新日期：2004-09-01 00:00:00

abstract：:This review deals with the biophysical aspects of flavin-based photosensors, comprising cryptochromes, LOV (Light, Oxygen and Voltage) and BLUF (Blue Light sensing Using FAD) proteins. Special emphasis is given to structural issues, photocycle quantum yields and energetics, mechanism of the light-triggered reactions, ...

journal_title：Photochemistry and photobiology

authors： Losi A

更新日期：2007-11-01 00:00:00

abstract：:Exposure to ultraviolet radiation is closely linked to the development of skin cancers in humans. The ultraviolet B (UVB) radiation wavelength (280-320 nm), in particular, causes DNA damage in epidermal keratinocytes, which are linked to the generation of signature premalignant mutations. Interactions between dermal f...

journal_title：Photochemistry and photobiology

authors： Fernandez TL,Van Lonkhuyzen DR,Dawson RA,Kimlin MG,Upton Z

更新日期：2014-11-01 00:00:00

abstract：:Generating accurate population-specific public health messages regarding sun protection requires knowledge about seasonal variation in sun exposure in different environments. To address this issue for a subtropical area of Australia, we used polysulphone badges to measure UVR for the township of Nambour (26 degrees la...

journal_title：Photochemistry and photobiology

authors： Neale RE,Hamilton AR,Janda M,Gies P,Green AC

更新日期：2010-03-01 00:00:00

abstract：:A targeting strategy based on the selective enzyme-mediated activation of polymeric photosensitizer prodrugs (PPP) within pathological tissue has led to the development of agents with the dual ability to detect and treat cancer. Herein, a detailed study of a simple model system for these prodrugs is described. We prep...

journal_title：Photochemistry and photobiology

authors： Campo MA,Gabriel D,Kucera P,Gurny R,Lange N

更新日期：2007-07-01 00:00:00

abstract：:Solar light leads to thymine dimers that are mutagenic and primary cause of skin cancer. Here, we report absorption and synchrotron radiation circular dichroism (CD) spectra of Tn single strands with different number n of bases (n = 2-7, 10, 11) recorded after various 254 nm irradiation times. From a principal compone...

journal_title：Photochemistry and photobiology

authors： Baggesen LM,Hoffmann SV,Nielsen SB

更新日期：2014-01-01 00:00:00

abstract：:Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

journal_title：Photochemistry and photobiology

authors： Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

更新日期：2016-09-01 00:00:00

abstract：:The size of excision repair patches corresponding to excision of (6-4) pyrimidine-pyrimidone photoproducts and (5-5, 6-6) cyclobutane dimers have been independently determined by using bromodeoxyuridine substitution and density increases in isopycnic gradients of small DNA fragments. The two classes of photoproducts w...

journal_title：Photochemistry and photobiology

authors： Cleaver JE,Jen J,Charles WC,Mitchell DL

更新日期：1991-09-01 00:00:00

abstract：:The energetic characteristics of selected reaction steps in the bacterial luciferase-catalyzed luminescence reaction were examined by computation using the MNDO-PM3 method. Specifically, a three-step model was proposed to account for the reaction between oxygen and reduced riboflavin 5'-phosphate (1,5H2-FMN) to genera...

journal_title：Photochemistry and photobiology

authors： Wada N,Sugimoto T,Watanabe H,Tu SC

更新日期：1999-07-01 00:00:00

abstract：:We studied the spectral characteristics of the larvae of three sympatric Belgian species of fireflies, Lampyris noctiluca, Phosphaenus hemipterus and Lamprohiza splendidula. An in vivo spectral study was performed to compare bioluminescence spectra. The emission spectrum of a laboratory reared female L. noctiluca was ...

journal_title：Photochemistry and photobiology

authors： De Cock R

更新日期：2004-04-01 00:00:00

abstract：:Although strong fluorescence makes the R-phycoerythrin (R-PE) proteins increasingly useful in biological and clinical assays, they are subject to nonlinear effects including transitions to collective dark states and photodegradation, which complicate quantitative applications. We report measurements of R-PE fluorescen...

journal_title：Photochemistry and photobiology

authors： Gaigalas A,Gallagher T,Cole KD,Singh T,Wang L,Zhang YZ

更新日期：2006-05-01 00:00:00

abstract：:Continuous red light controls starch degradation in turions of Spirodela polyrhiza [Dölger, K., U. K. Tirlapur and K.-J. Appenroth [1997] Photochem. Photobiol. 66, 126-127 (1997)]. This light could be replaced by repeated red light pulses with the reciprocity law fulfilled over a large range of fluence rates. The effe...

journal_title：Photochemistry and photobiology

authors： Appenroth KJ,Gabrys H

更新日期：2001-01-01 00:00:00

abstract：:The pyrimidine nucleobases contained in DNA undergo a variety of photoinduced reactions in which two moieties become joined to form a product (e.g. formation of cyclobutane dimers and [6-4] adducts). Herein, we describe a new type of photoconjugation reaction that has been shown to occur for 5-methylcytosine (5-MeC), ...

journal_title：Photochemistry and photobiology

authors： Shetlar MD,Chung J

更新日期：2012-03-01 00:00:00

abstract：:UV rays may cause several degrees of skin damage, which makes sunscreen research necessary. In addition, skin sensitivity shows daily variations, which can interfere in the detection of the efficacy of the filters. Here, we studied the UV-induced erythema in hairless rats at two times of the day (light and darkness) u...

journal_title：Photochemistry and photobiology

authors： Flo A,Calpena AC,Díez-Noguera A,Del Pozo A,Cambras T

更新日期：2017-03-01 00:00:00

abstract：:The modifications induced by reactive oxygen species (ROS) on fluorescent proteins (FPs) may have important implications for live cell fluorescence imaging. Using quantitative gamma-radiolysis, we have studied the ROS-induced biochemical and photophysical perturbations on recombinant cyan fluorescent protein (CFP). Af...

journal_title：Photochemistry and photobiology

authors： Alvarez L,Levin CH,Merola F,Bizouarn T,Pasquier H,Baciou L,Rusconi F,Erard M

更新日期：2010-01-01 00:00:00

abstract：:We investigated the hypothesis that the strength of the activation of the intra-S DNA damage checkpoint varies within the S phase. Synchronized diploid human fibroblasts were exposed to either 0 or 2.5 J m(-2) UVC in early, mid- and late-S phase. The endpoints measured were the following: (1) radio-resistant DNA synth...

journal_title：Photochemistry and photobiology

authors： Chastain PD 2nd,Brylawski BP,Zhou YC,Rao S,Chu H,Ibrahim JG,Kaufmann WK,Cordeiro-Stone M

更新日期：2015-01-01 00:00:00

abstract：:The retinal protonated Schiff base of bacteriorhodopsin is photoreactive to reducing agents such as NaBH4. In the present work we have studied the effect of different protein hydration levels on the photoreductive reaction, as well as the consequences of preventing isomerization around the critical C13=C14 retinal dou...

journal_title：Photochemistry and photobiology

authors： Aharoni A,Ottolenghi M,Sheves M

更新日期：2002-06-01 00:00:00