Effect of bronchopulmonary lavage on lung retention and clearance of particulate material in hamsters.

abstract：:Prostaglandin-H synthase is unique among enzymes of the plant and animal kingdom in its ability to biosynthesize and metabolize hydroperoxides. Its cyclooxygenase activity oxygenates polyunsaturated fatty acids to hydroperoxy endoperoxides, and its peroxidase activity reduces the hydroperoxy group to hydroxy groups. H...

journal_title：Environmental health perspectives

authors： Marnett LJ

更新日期：1990-08-01 00:00:00

abstract：:We present evidence that the El Niño phenomenon intensifies the annual cycle of malaria cases for Plasmodium vivax and Plasmodium falciparum in endemic areas of Colombia as a consequence of concomitant anomalies in the normal annual cycle of temperature and precipitation. We used simultaneous analyses of both variable...

journal_title：Environmental health perspectives

authors： Poveda G,Rojas W,Quiñones ML,Vélez ID,Mantilla RI,Ruiz D,Zuluaga JS,Rua GL

更新日期：2001-05-01 00:00:00

abstract：:This paper will briefly outline those elements which must be considered in assessing the effects of any given compound which might impinge on the actions of adrenocortical steroids. Considerations that ought to be taken into account include the following: the delivery to the affected cells of corticosteroids, the upta...

journal_title：Environmental health perspectives

authors： Thompson EB

更新日期：1981-04-01 00:00:00

abstract：:Inspection of the available literature reveals that a detailed investigation of the aqueous organic chemistry of chlorine dioxide and systematic identification of products formed during water disinfection has not been considered. This must be done before an informed assessment can be made of the relative safety of usi...

journal_title：Environmental health perspectives

authors： Stevens AA

更新日期：1982-12-01 00:00:00

abstract：:In recent years there have been a significant number of publications on the benefits and challenges of community-based participatory research (CBPR). In this introduction we give an overview of three projects presented in this mini-monograph and highlight their commonalities and differences in developing community-uni...

journal_title：Environmental health perspectives

authors： Srinivasan S,Collman GW

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Warm sea surface temperatures (SSTs) are positively related to incidence of ciguatera fish poisoning (CFP). Increased severe storm frequency may create more habitat for ciguatoxic organisms. Although climate change could expand the endemic range of CFP, the relationship between CFP incidence and specific env...

journal_title：Environmental health perspectives

authors： Gingold DB,Strickland MJ,Hess JJ

更新日期：2014-06-01 00:00:00

abstract：:The importance of urban dust as a source of lead for young children is still disputed. Although blood-lead data from various population surveys usually show a peak concentration in early childhood, there is evidence that such a peak is small or absent altogether in children without much access to the general environme...

journal_title：Environmental health perspectives

authors： Duggan MJ

更新日期：1983-04-01 00:00:00

abstract：:Metallothioneins (MTs) are encoded by a multigene family in man. We have isolated those genes and analyzed the structure of some of them. The MT-II variant is encoded by a single functional gene: MT-IIA. The MT-IIB gene is a processed pseudogene derived from a reverse transcript of MT-II mRNA. On the other hand, the M...

journal_title：Environmental health perspectives

authors： Karin M,Richards RI

更新日期：1984-03-01 00:00:00

abstract：:Lung counting is highly geometry dependent, especially at low photon energies. Monte Carlo simulations have been used to determine the magnitude of the errors obtained if it is assumed that the deposition is homogeneous, when in fact it is not. Simulation for a germanium lung counting system consisting of four, 70 mm ...

journal_title：Environmental health perspectives

authors： Kramer GH

更新日期：1997-12-01 00:00:00

abstract：:A comprehensive effort was undertaken to identify articles demonstrating chemical hormesis. Nearly 4000 potentially relevant articles were retrieved from preliminary computer database searches by using various key word descriptors and extensive cross-referencing. A priori evaluation criteria were established including...

journal_title：Environmental health perspectives

authors： Calabrese EJ,Baldwin LA

更新日期：1998-02-01 00:00:00

abstract：:Noise exposure causes changes at different levels in human organs, particularly the cardiovascular system, where it is responsible for increasing heart rate, peripheral vascular resistance, and blood pressure. In this study, we evaluated the effect of noise exposure on DNA integrity and ultrastructure of rat cardiomyo...

journal_title：Environmental health perspectives

authors： Lenzi P,Frenzilli G,Gesi M,Ferrucci M,Lazzeri G,Fornai F,Nigro M

更新日期：2003-04-01 00:00:00

abstract：:An important public health challenge has been the need to protect children's health. To accomplish this goal, the scientific community needs scientifically based child-specific risk assessment methods. Critical to their development is the need to understand mechanisms underlying children's sensitivity to environmental...

journal_title：Environmental health perspectives

authors： Faustman EM,Silbernagel SM,Fenske RA,Burbacher TM,Ponce RA

更新日期：2000-03-01 00:00:00

abstract：:In recent years there has been an increasing focus in environmental risk assessment on children as a potentially susceptible population. There also has been growing recognition of the need for a systematic approach for organizing, evaluating, and incorporating the available data on children's susceptibilities in risk ...

journal_title：Environmental health perspectives

authors： Daston G,Faustman E,Ginsberg G,Fenner-Crisp P,Olin S,Sonawane B,Bruckner J,Breslin W,McLaughlin TJ

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Many pesticides in current use have recently been revealed as in vitro androgen receptor (AR) antagonists, but information about their combined effects is lacking. OBJECTIVE:We investigated the combined effects and the competitive AR antagonism of pesticide mixtures. METHODS:We used the MDA-kb2 assay to te...

journal_title：Environmental health perspectives

authors： Orton F,Rosivatz E,Scholze M,Kortenkamp A

更新日期：2012-11-01 00:00:00

abstract：:Most contemporary bioinsecticides are derived from scaled-up cultures of Bacillus thuringiensis subspecies israelensis (Bti) and kurstaki (Btk), whose particulate fractions contain mostly B. thuringiensis spores (> 10(12)/L) and proteinaceous aggregates, including crystal-like parasporal inclusion bodies (PIB). Based ...

journal_title：Environmental health perspectives

authors： Tayabali AF,Seligy VL

更新日期：2000-10-01 00:00:00

abstract：:The purpose of the study was to determine whether the risk of childhood acute lymphoblastic leukemia (ALL) associated with drinking water disinfection by-products was modified in the presence of variants in genes involved in the metabolism of trihalomethanes (THMs). We included a subset of cases from a population-base...

journal_title：Environmental health perspectives

authors： Infante-Rivard C,Amre D,Sinnett D

更新日期：2002-06-01 00:00:00

abstract：:The U.S. Environmental Protection Agency is under a congressional mandate to revise its current standard for arsenic in drinking water. We present a risk assessment for cancers of the bladder, liver, and lung from exposure to arsenic in water, based on data from 42 villages in an arseniasis-endemic region of Taiwan. W...

journal_title：Environmental health perspectives

authors： Morales KH,Ryan L,Kuo TL,Wu MM,Chen CJ

更新日期：2000-07-01 00:00:00

abstract：:The instrumentation and practical circuitry required for the detection of negative ions exiting the mass analysis section of a mass spectrometer is examined. The potentials needed to bias the electron multiplier when detecting negative ions from a low ion-energy mass spectrometer, e.g., a quadrupole, are contrasted wi...

journal_title：Environmental health perspectives

authors： McKeown M

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Bacterial meningitis causes a high burden of disease in the African meningitis belt, with regular seasonal hyperendemicity and sporadic short, but intense, localized epidemics during the late dry season occurring at a small spatial scale [i.e., below the district level, in individual health centers (HCs)]. I...

journal_title：Environmental health perspectives

authors： Woringer M,Martiny N,Porgho S,Bicaba BW,Bar-Hen A,Mueller JE

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. OBJECTIVE:We investigated the impact of tolerated and toxic arsenic trioxide (As2O3) e...

journal_title：Environmental health perspectives

authors： Rahman S,Housein Z,Dabrowska A,Mayán MD,Boobis AR,Hajji N

更新日期：2015-05-01 00:00:00

abstract：:In this article we report a simple and efficient method for detecting nonsteroidal estrogens in a biologic sample. This method uses polyclonal antibodies to estradiol (E2) to immunoprecipitate these major biologically active steroidal estrogens, leaving behind the nonsteroidal estrogens, which are then detected in a c...

journal_title：Environmental health perspectives

authors： Natarajan K,Overstreet JW,Rogers JM,Denison MS,Chen J,Lohstroh PN,McConnell DS,Lasley BL

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions of adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with a higher cumulative RF-EMF brain dose in ad...

journal_title：Environmental health perspectives

authors： Foerster M,Thielens A,Joseph W,Eeftens M,Röösli M

更新日期：2018-07-23 00:00:00

abstract：:A previously healthy woman developed hypersensitivity pneumonitis of such severity that she required chronic systemic corticosteroid therapy for symptom control. Detailed investigation of her workplace and home environments revealed fungi in her typical suburban home, to which she had specific serum precipitating anti...

journal_title：Environmental health perspectives

authors： Apostolakos MJ,Rossmoore H,Beckett WS

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:High-level occupational exposures to some industrial chemicals have been associated with liver diseases, including nonalcoholic fatty liver disease (NAFLD). However, the potential role of low-level environmental pollution on liver disease in the general population has not been evaluated. OBJECTIVE:We determ...

journal_title：Environmental health perspectives

authors： Cave M,Appana S,Patel M,Falkner KC,McClain CJ,Brock G

更新日期：2010-12-01 00:00:00

abstract：:In this study, we explored the efficacy of upper-room ultraviolet germicidal irradiation (UVGI) in reducing the concentration of Serratia marcescens and Mycobacterium bovis bacille Calmette-Guérin (BCG) aerosols in enclosed places. We constructed a facility (4.5 m x 3 m x 2.9 m) in which both ceiling- and wall-mounted...

journal_title：Environmental health perspectives

authors： Ko G,First MW,Burge HA

更新日期：2002-01-01 00:00:00

abstract：:An impressive array of evidence has been obtained during the past decade establishing correlations between specific DNA adducts and carcinogenesis. Many of the studies utilized organ specific differences in carcinogenesis to establish the correlations. More recently, we have investigated similar relationships between ...

journal_title：Environmental health perspectives

authors： Swenberg JA,Richardson FC,Boucheron JA,Dyroff MC

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Tens of millions of Americans suffer from a range of adverse health outcomes due to noise exposure, including heart disease and hearing loss. Reducing environmental noise pollution is achievable and consistent with national prevention goals, yet there is no national plan to reduce environmental noise polluti...

journal_title：Environmental health perspectives

authors： Hammer MS,Swinburn TK,Neitzel RL

更新日期：2014-02-01 00:00:00

abstract：:Polychlorinated dibenzo-p-dioxins (PCDDs, dioxins), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are environmental endocrine disruptors that have half-lives of 7-10 years in the human body and have toxicities that probably include carcinogenesis. A high ratio of 4-hydroxyl estradiol (4-O...

journal_title：Environmental health perspectives

authors： Wang SL,Chang YC,Chao HR,Li CM,Li LA,Lin LY,Päpke O

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Exposure to perfluorooctane sulfonic acid (PFOS) or to perfluorooctanoic acid (PFOA) increases mouse and human peroxisome proliferator-activated receptor alpha (PPARα) subtype activity, which influences lipid metabolism. Because cholesterol is the substrate from which testosterone is synthesized, exposure to...

journal_title：Environmental health perspectives

authors： Maisonet M,Calafat AM,Marcus M,Jaakkola JJ,Lashen H

更新日期：2015-12-01 00:00:00

abstract：:The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the to...

journal_title：Environmental health perspectives

authors： Clarkson TW

更新日期：2002-02-01 00:00:00