Reaction products of chlorine dioxide.

abstract：:The identification of certain organic compounds in drinking water has led water treatment specialists to be increasingly concerned about the eventual risks of such pollutants to the health of consumers. Our experiments focused on the role of ozone and granular activated carbon in removing mutagenic compounds and precu...

journal_title：Environmental health perspectives

authors： Bourbigot MM,Hascoet MC,Levi Y,Erb F,Pommery N

更新日期：1986-11-01 00:00:00

abstract：:There is an increasing interest in the development and validation of biomarkers for use in biochemical/molecular epidemiological studies. Though the area of neurotoxicology has received much attention in the past several years, it still lags behind with regard to the development of biomarkers, particularly those of he...

journal_title：Environmental health perspectives

authors： Costa LG

更新日期：1996-03-01 00:00:00

abstract：:Human fibroblasts (HFW) were 10-fold more susceptible than Chinese hamster ovary (CHO-K1) cells to sodium arsenite. Comparison of cellular antioxidant enzyme activities showed that CHO-K1 cells contained 3- and 8-fold more glutathione-peroxidase and catalase activities, respectively, than HFW cells. Since vitamin E, m...

journal_title：Environmental health perspectives

authors： Lee TC,Ho IC

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Although a long latency period of toxicity after exposure to methylmercury (MeHg) is known to exist in humans, few animal studies have addressed this issue. Substantiation of delayed MeHg toxicity in animals would affect the risk evaluation of MeHg. OBJECTIVES:Our goal in this study was to demonstrate the e...

journal_title：Environmental health perspectives

authors： Yoshida M,Shimizu N,Suzuki M,Watanabe C,Satoh M,Mori K,Yasutake A

更新日期：2008-06-01 00:00:00

abstract：:Health is defined as homeostasis of the cellular ecology, and a state where there has not been an inordinate loss, reversible or irreversible, of the structural and/or functional reserves of the body. An adverse health effect is defined as the causation, promotion, facilitation and/or exacerbation of a structural and/...

journal_title：Environmental health perspectives

authors： Sherwin RP

更新日期：1983-10-01 00:00:00

abstract：:An important public health challenge has been the need to protect children's health. To accomplish this goal, the scientific community needs scientifically based child-specific risk assessment methods. Critical to their development is the need to understand mechanisms underlying children's sensitivity to environmental...

journal_title：Environmental health perspectives

authors： Faustman EM,Silbernagel SM,Fenske RA,Burbacher TM,Ponce RA

更新日期：2000-03-01 00:00:00

abstract：:Restriction-fragment-length polymorphism analysis was performed on several different types of human cancers, including carcinoma of the uterine cervix, neuroblastoma, hepatocellular carcinoma, pheochromocytoma, stomach cancer, and small-cell lung carcinoma (SCLC), to determine the chromosomal loci of putative tumor-su...

journal_title：Environmental health perspectives

authors： Yokota J,Sugimura T,Terada M

更新日期：1991-06-01 00:00:00

abstract：:The Sertoli cell is the primary target for FSH action in the mammalian testis. These cells contain the majority of testicular plasma membrane receptors for this hormone. Receptor occupancy is directly correlated with a stimulation of adenylyl cyclase and a decrease in the activity of a cytoplasmic Ca++-sensitive cAMP ...

journal_title：Environmental health perspectives

authors： Tindall DJ,Tash JS,Means AR

更新日期：1981-04-01 00:00:00

abstract：:Numerous publications and reports have expressed health and safety concerns about the production and use of nanoparticles, especially in areas of exposure monitoring, personal use, and environmental fate and transport. We suggest that stable isotopic tracers, which have been used widely in the earth sciences and in me...

journal_title：Environmental health perspectives

authors： Gulson B,Wong H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Perfluoroalkyl substances (PFASs) are synthetic compounds that are widely used in industry and are often detectable in humans. In pregnant rats and their pups, PFASs can interfere with thyroid hormone homeostasis. In humans, maternal thyroid hormones supply the fetus throughout pregnancy, and thyroid hormone...

journal_title：Environmental health perspectives

authors： Wang Y,Rogan WJ,Chen PC,Lien GW,Chen HY,Tseng YC,Longnecker MP,Wang SL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Hydraulically fractured wells produce 2-14 million liters of wastewater, which may contain toxic and radioactive compounds. The wastewater is predominantly disposed of using Class II injection wells. OBJECTIVE:Our objective was to evaluate the relationship between sociodemographic characteristics and inject...

journal_title：Environmental health perspectives

authors： Silva GS,Warren JL,Deziel NC

更新日期：2018-06-27 00:00:00

abstract：:The dissolution of mineral fibers has been studied in simulated physiological fluids using a dynamic testing procedure. Fibers of different chemical composition and obtained by different processes with a mean diameter of about 1 micron, have been characterized with respect to their solubility under various test condit...

journal_title：Environmental health perspectives

authors： Lehuédé P,de Meringo A

更新日期：1994-10-01 00:00:00

abstract：:A wide variety of behavioral methods has been employed with animals to assess visual changes induced by drugs or toxicants. The methods range from simple to complex, from broad screening devices to narrowly focused techniques. Their relative advantages for the environmental toxicologist are discussed. Manipulation of ...

journal_title：Environmental health perspectives

authors： Evans HL

更新日期：1978-10-01 00:00:00

abstract：:We present a case of a diamond polisher who developed occupational asthma as a result of prolonged exposure to various potent and well-recognized asthma-inducing agents, including cobalt dust. Although the patient was seen by various medical professionals during the initial course of his illness and given an early dia...

journal_title：Environmental health perspectives

authors： Wilk-Rivard E,Szeinuk J

更新日期：2001-12-01 00:00:00

abstract：:Spatial epidemiology is the description and analysis of geographic variations in disease with respect to demographic, environmental, behavioral, socioeconomic, genetic, and infectious risk factors. We focus on small-area analyses, encompassing disease mapping, geographic correlation studies, disease clusters, and clus...

journal_title：Environmental health perspectives

authors： Elliott P,Wartenberg D

更新日期：2004-06-01 00:00:00

abstract：:Dose influences mechanism; and over a wide range of doses, one can envision that mechanism will change with changing dose. This basic concept in toxicology is juxtaposed with the biologic importance of maintaining normal DNA methylation status to provide the focus of this paper. The idea that altered DNA methylation p...

journal_title：Environmental health perspectives

authors： Goodman JI

更新日期：1998-02-01 00:00:00

abstract：:In vivo bone lead measurement using K X-ray fluorescence (KXRF) has been used to estimate long-term lead exposure, especially in adults. Relatively few studies have been conducted on young subjects with this technique. To explore the measurement variability of KXRF bone lead measurements in young subjects, the tibiae ...

journal_title：Environmental health perspectives

authors： Hoppin JA,Aro A,Hu H,Ryan PB

更新日期：2000-03-01 00:00:00

abstract：:A major concern of the chlorination of aquatic humic materials is the ubiquitous production of trihalomethanes. A large number of other chlorinated organic compounds, however, have been shown to be formed by chlorine's reaction with humic substances. In this study, humic material was concentrated from a coastal North ...

journal_title：Environmental health perspectives

authors： Johnson JD,Christman RF,Norwood DL,Millington DS

更新日期：1982-12-01 00:00:00

abstract：:Soil samples were collected from 28 fields which had received manure from Michigan's most highly contaminated dairy herds. The number of fields in each concentration range of PBB in soil were: 2, not detectable; 15, 0.0 to 8.0 ppb; 6, 14-102 ppb, and 5, 153 to 371 ppb. Plant tissue sampled from the 10 most highly cont...

journal_title：Environmental health perspectives

authors： Jacobs LW,Chou SF,Tiedje JM

更新日期：1978-04-01 00:00:00

abstract：:Short-term increases in ambient air pollution have been associated with an increased incidence of acute cardiac events. We assessed the effect of inhalation exposure to concentrated ambient particles (CAPs) on myocardial ischemia in a canine model of coronary artery occlusion. Six mongrel dogs underwent thoracotomy fo...

journal_title：Environmental health perspectives

authors： Wellenius GA,Coull BA,Godleski JJ,Koutrakis P,Okabe K,Savage ST,Lawrence JE,Murthy GG,Verrier RL

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Evidence suggests that cardiovascular effects of air pollution are mediated by inflammation and that air pollution can induce genetic expression of the interleukin-6 gene (IL6). OBJECTIVES:We investigated whether IL6 and fibrinogen gene variants can affect plasma IL-6 responses to air pollution in patients ...

journal_title：Environmental health perspectives

authors： Ljungman P,Bellander T,Schneider A,Breitner S,Forastiere F,Hampel R,Illig T,Jacquemin B,Katsouyanni K,von Klot S,Koenig W,Lanki T,Nyberg F,Pekkanen J,Pistelli R,Pitsavos C,Rosenqvist M,Sunyer J,Peters A

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:There is general concern that persistent organic pollutants (POPs) found in the environment, wildlife, food, water, house dust, human tissues, and fluids may alter normal human physiologic activities (e.g., fetal development, immune and endocrine systems). Although the levels of some POPs [polychlorinated bi...

journal_title：Environmental health perspectives

authors： Doucet J,Tague B,Arnold DL,Cooke GM,Hayward S,Goodyer CG

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Increasing evidence suggests a proatherogenic role for lipoprotein-associated phospholipase A₂ (Lp-PLA2). A meta-analysis of published cohorts has shown that Lp-PLA2 is an independent predictor of coronary heart disease events and stroke. OBJECTIVE:In this study, we investigated whether the association betw...

journal_title：Environmental health perspectives

authors： Brüske I,Hampel R,Baumgärtner Z,Rückerl R,Greven S,Koenig W,Peters A,Schneider A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and...

journal_title：Environmental health perspectives

authors： Malloy TF,Zaunbrecher VM,Batteate CM,Blake A,Carroll WF Jr,Corbett CJ,Hansen SF,Lempert RJ,Linkov I,McFadden R,Moran KD,Olivetti E,Ostrom NK,Romero M,Schoenung JM,Seager TP,Sinsheimer P,Thayer KA

更新日期：2017-06-13 00:00:00

abstract：:Following our first report on elevated polybrominated diphenyl ether (PBDE) concentrations in California women, we expanded our investigation to include diverse groups of local women. We analyzed additional adipose and serum samples collected in the late 1990s from San Francisco Bay Area women participating in a breas...

journal_title：Environmental health perspectives

authors： Petreas M,She J,Brown FR,Winkler J,Windham G,Rogers E,Zhao G,Bhatia R,Charles MJ

更新日期：2003-07-01 00:00:00

abstract：:Mass poisonings, called yusho and yu-cheng, occurred in western Japan in 1968 and central Taiwan in 1979, respectively. These occurrences were separately caused by ingestion of rice oils contaminated with polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs) and polychlorinated quaterphenyls. The tot...

journal_title：Environmental health perspectives

authors： Masuda Y

更新日期：1985-05-01 00:00:00

abstract：:This working paper summarizes the known ultrastructural and biochemical effects of lead, mercury, cadmium, and arsenic on subcellular organelle systems following in vivo administration. Documented metal-induced alterations in nuclear, mitochondrial, microsomal, and lysosomal functions are discussed in relation to thei...

journal_title：Environmental health perspectives

authors： Fowler BA

更新日期：1978-02-01 00:00:00

abstract：:The U.S. Environmental Protection Agency is under a congressional mandate to revise its current standard for arsenic in drinking water. We present a risk assessment for cancers of the bladder, liver, and lung from exposure to arsenic in water, based on data from 42 villages in an arseniasis-endemic region of Taiwan. W...

journal_title：Environmental health perspectives

authors： Morales KH,Ryan L,Kuo TL,Wu MM,Chen CJ

更新日期：2000-07-01 00:00:00

abstract：:We investigated the metabolic fate of a low dose (25 micro g/kg) of bisphenol A [2,2-bis(4-hydroxy-phenyl)propane] (BPA) injected subcutaneously in CD1 pregnant mice using a tritium-labeled molecule. Analytic methods were developed to allow a radio-chromatographic profiling of BPA residues in excreta and tissues, as w...

journal_title：Environmental health perspectives

authors： Zalko D,Soto AM,Dolo L,Dorio C,Rathahao E,Debrauwer L,Faure R,Cravedi JP

更新日期：2003-03-01 00:00:00

abstract：:We developed a sensitive and accurate analytical method for quantifying methyleugenol (ME) in human serum. Our method uses a simple solid-phase extraction followed by a highly specific analysis using isotope dilution gas chromatography-high resolution mass spectrometry. Our method is very accurate; its limit of detect...

journal_title：Environmental health perspectives

authors： Barr DB,Barr JR,Bailey SL,Lapeza CR Jr,Beeson MD,Caudill SP,Maggio VL,Schecter A,Masten SA,Lucier GW,Needham LL,Sampson EJ

更新日期：2000-04-01 00:00:00