听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览ENVIRONMENTAL HEALTH PERSPECTIVES期刊下所有文献
  • Exposure of Adult Female Mice to Low Doses of di(2-ethylhexyl) Phthalate Alone or in an Environmental Phthalate Mixture: Evaluation of Reproductive Behavior and Underlying Neural Mechanisms.

    abstract:BACKGROUND:We have previously shown that adult male mice exposure to low doses of an ubiquitous endocrine disruptor, di(2-ethylhexyl) phthalate (DEHP), alters courtship behavior. OBJECTIVE:The effects of adult exposure to low doses of DEHP alone or in an environmental phthalate mixture on estrous cyclicity, reproducti...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP7662

    authors: Adam N,Brusamonti L,Mhaouty-Kodja S

    更新日期:2021-01-01 00:00:00

  • Low-Dose Bisphenol A in a Rat Model of Endometrial Cancer: A CLARITY-BPA Study.

    abstract:BACKGROUND:Bisphenol A (BPA) is known to be biologically active in experimental models even at low levels of exposure. However, its impact on endometrial cancer remains unclear. OBJECTIVES:This study aimed to investigate whether lifelong exposure to different doses of BPA induced uterine abnormalities and molecular ch...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6875

    authors: Leung YK,Biesiada J,Govindarajah V,Ying J,Kendler A,Medvedovic M,Ho SM

    更新日期:2020-12-01 00:00:00

  • Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model.

    abstract:BACKGROUND:Harmful algal blooms (HABs) produce potent neurotoxins that threaten human health, but current regulations may not be protective of sensitive populations. Early life exposure to low levels of the HAB toxin domoic acid (DomA) produces long-lasting behavioral deficits in rodent and primate models; however, the...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6652

    authors: Panlilio JM,Aluru N,Hahn ME

    更新日期:2020-11-01 00:00:00

  • Chemical Characterization of a Legacy Aqueous Film-Forming Foam Sample and Developmental Toxicity in Zebrafish (Danio rerio).

    abstract:BACKGROUND:Drinking water contamination related to the use of aqueous film-forming foam (AFFF) has been documented at hundreds of military bases, airports, and firefighter training facilities. AFFF has historically contained high levels of long-chain per- and polyfluoroalkyl substances (PFAS), which pose serious health...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6470

    authors: Annunziato KM,Doherty J,Lee J,Clark JM,Liang W,Clark CW,Nguyen M,Roy MA,Timme-Laragy AR

    更新日期:2020-09-01 00:00:00

  • Occupational Pesticide Use and Risk of Renal Cell Carcinoma in the Agricultural Health Study.

    abstract:BACKGROUND:Agricultural work and occupational pesticide use have been associated with increased risk of renal cell carcinoma (RCC), the most common form of kidney cancer. However, few prospective studies have investigated links to specific pesticides. OBJECTIVE:We evaluated the lifetime use of individual pesticides an...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6334

    authors: Andreotti G,Beane Freeman LE,Shearer JJ,Lerro CC,Koutros S,Parks CG,Blair A,Lynch CF,Lubin JH,Sandler DP,Hofmann JN

    更新日期:2020-06-01 00:00:00

  • Locus-Specific Differential DNA Methylation and Urinary Arsenic: An Epigenome-Wide Association Study in Blood among Adults with Low-to-Moderate Arsenic Exposure.

    abstract:BACKGROUND:Chronic exposure to arsenic (As), a human toxicant and carcinogen, remains a global public health problem. Health risks persist after As exposure has ended, suggesting epigenetic dysregulation as a mechanistic link between exposure and health outcomes. OBJECTIVES:We investigated the association between tota...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6263

    authors: Bozack AK,Domingo-Relloso A,Haack K,Gamble MV,Tellez-Plaza M,Umans JG,Best LG,Yracheta J,Gribble MO,Cardenas A,Francesconi KA,Goessler W,Tang WY,Fallin MD,Cole SA,Navas-Acien A

    更新日期:2020-06-01 00:00:00

  • Road Traffic Noise Exposure and Filled Prescriptions for Antihypertensive Medication: A Danish Cohort Study.

    abstract:BACKGROUND:Epidemiological research on effects of transportation noise on incident hypertension is inconsistent. OBJECTIVES:We aimed to investigate whether residential road traffic noise increases the risk for hypertension. METHODS:In a population-based cohort of 57,053 individuals 50-64 years of age at enrollment, w...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6273

    authors: Thacher JD,Poulsen AH,Roswall N,Hvidtfeldt U,Raaschou-Nielsen O,Jensen SS,Ketzel M,Brandt J,Overvad K,Tjønneland A,Münzel T,Sørensen M

    更新日期:2020-05-01 00:00:00

  • A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study.

    abstract:BACKGROUND:The Consortium Linking Academic and Regulatory Insights on Bisphenol-A (CLARITY-BPA) is a rare collaboration of guideline-compliant (core) studies and academic hypothesis-based studies to assess the effects of bisphenol A (BPA). OBJECTIVES:We aimed to a) determine whether BPA showed effects on the developin...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6301

    authors: Montévil M,Acevedo N,Schaeberle CM,Bharadwaj M,Fenton SE,Soto AM

    更新日期:2020-05-01 00:00:00

  • Maternal Plasma Perfluoroalkyl Substances and Miscarriage: A Nested Case-Control Study in the Danish National Birth Cohort.

    abstract:BACKGROUND:Per- and polyfluoroalkyl substances (PFAS) are widespread persistent organic pollutants and endocrine disruptors. High doses of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) exposure can cause pregnancy loss and infant deaths in animals, but the associations between PFAS exposures and...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6202

    authors: Liew Z,Luo J,Nohr EA,Bech BH,Bossi R,Arah OA,Olsen J

    更新日期:2020-04-01 00:00:00

  • Neuroinflammatory and Behavioral Outcomes Measured in Adult Offspring of Mice Exposed Prenatally to E-Cigarette Aerosols.

    abstract:BACKGROUND:In an effort to decrease the rates of smoking conventional tobacco cigarettes, electronic cigarettes (e-cigarettes) have been proposed as an effective smoking cessation tool. However, little is known about their toxicological impacts. This is concerning given that e-cigarette use is perceived as less harmful...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6067

    authors: Church JS,Chace-Donahue F,Blum JL,Ratner JR,Zelikoff JT,Schwartzer JJ

    更新日期:2020-04-01 00:00:00

  • A Quantile-Based g-Computation Approach to Addressing the Effects of Exposure Mixtures.

    abstract:BACKGROUND:Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about exposure mixtures, including methods such as weighted quantile sum (WQS) regression that estimate a joint effect o...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5838

    authors: Keil AP,Buckley JP,O'Brien KM,Ferguson KK,Zhao S,White AJ

    更新日期:2020-04-01 00:00:00

  • Role of TET Dioxygenases and DNA Hydroxymethylation in Bisphenols-Stimulated Proliferation of Breast Cancer Cells.

    abstract:BACKGROUND:Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor targeting estrogen receptors (ERs), has been implicated in the promotion of breast cancer. Perinatal exposure of BPA could induce longitudinal alteration of DNA hydroxymethylation in imprinted loci of mouse blood cells. To date, no data has be...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5862

    authors: Li Z,Lyu C,Ren Y,Wang H

    更新日期:2020-02-01 00:00:00

  • CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.

    abstract:BACKGROUND:Endocrine disrupting chemicals (EDCs) are xenobiotics that mimic the interaction of natural hormones and alter synthesis, transport, or metabolic pathways. The prospect of EDCs causing adverse health effects in humans and wildlife has led to the development of scientific and regulatory approaches for evaluat...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5580

    authors: Mansouri K,Kleinstreuer N,Abdelaziz AM,Alberga D,Alves VM,Andersson PL,Andrade CH,Bai F,Balabin I,Ballabio D,Benfenati E,Bhhatarai B,Boyer S,Chen J,Consonni V,Farag S,Fourches D,García-Sosa AT,Gramatica P,Grisoni F

    更新日期:2020-02-01 00:00:00

  • Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice.

    abstract:BACKGROUND:Endocrine-disrupting chemicals have been shown to have broad effects on development, but their mutagenic actions that can lead to cancer have been less clearly demonstrated. Physiological levels of estrogen have been shown to stimulate DNA damage in breast epithelial cells through mechanisms mediated by estr...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5221

    authors: Majhi PD,Sharma A,Roberts AL,Daniele E,Majewski AR,Chuong LM,Black AL,Vandenberg LN,Schneider SS,Dunphy KA,Jerry DJ

    更新日期:2020-01-01 00:00:00

  • New Perspectives for Cancer Hazard Evaluation by the Report on Carcinogens: A Case Study Using Read-Across Methods in the Evaluation of Haloacetic Acids Found as Water Disinfection By-Products.

    abstract:BACKGROUND:Due to the large number of chemicals not yet tested for carcinogenicity but to which people are exposed, the limited number of human and animal cancer studies conducted each year, and the frequent need for a timely response, mechanistic data are playing an increasingly important role in carcinogen hazard ide...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5672

    authors: Atwood ST,Lunn RM,Garner SC,Jahnke GD

    更新日期:2019-12-01 00:00:00

  • Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research.

    abstract:BACKGROUND:The National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use. The challenge is to prioritize chemicals for biomonitoring that may prese...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5133

    authors: Pellizzari ED,Woodruff TJ,Boyles RR,Kannan K,Beamer PI,Buckley JP,Wang A,Zhu Y,Bennett DH,(Environmental influences on Child Health Outcomes).

    更新日期:2019-12-01 00:00:00

  • Suicide and Ambient Temperature: A Multi-Country Multi-City Study.

    abstract:BACKGROUND:Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. OBJECTIVES:We examined the short-term temperature-su...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP4898

    authors: Kim Y,Kim H,Gasparrini A,Armstrong B,Honda Y,Chung Y,Ng CFS,Tobias A,Íñiguez C,Lavigne E,Sera F,Vicedo-Cabrera AM,Ragettli MS,Scovronick N,Acquaotta F,Chen BY,Guo YL,Seposo X,Dang TN,de Sousa Zanotti Stagliorio Coel

    更新日期:2019-11-01 00:00:00

  • Prenatal Exposure to PM2.5 and Cardiac Vagal Tone during Infancy: Findings from a Multiethnic Birth Cohort.

    abstract:BACKGROUND:The autonomic nervous system plays a key role in maintaining homeostasis and responding to external stimuli. In adults, exposure to fine particulate matter ( PM ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP4434

    authors: Cowell WJ,Brunst KJ,Malin AJ,Coull BA,Gennings C,Kloog I,Lipton L,Wright RO,Enlow MB,Wright RJ

    更新日期:2019-10-01 00:00:00

  • Inter-host Transmission of Carbapenemase-Producing Escherichia coli among Humans and Backyard Animals.

    abstract:BACKGROUND:The rapidly increasing dissemination of carbapenem-resistant Enterobacteriaceae (CRE) in both humans and animals poses a global threat to public health. However, the transmission of CRE between humans and animals has not yet been well studied. OBJECTIVES:We investigated the prevalence, risk factors, and dri...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5251

    authors: Li J,Bi Z,Ma S,Chen B,Cai C,He J,Schwarz S,Sun C,Zhou Y,Yin J,Hulth A,Wang Y,Shen Z,Wang S,Wu C,Nilsson LE,Walsh TR,Börjesson S,Shen J,Sun Q,Wang Y

    更新日期:2019-10-01 00:00:00

  • Transfer and Metabolism of the Xenoestrogen Zearalenone in Human Perfused Placenta.

    abstract:BACKGROUND:Pregnancy is a sensitive condition during which adverse environmental exposures should be monitored thoroughly and minimized whenever possible. In particular, the hormone balance during gestation is delicate, and disturbance may cause acute or chronic long-term health effects. A potential endocrine disruptio...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP4860

    authors: Warth B,Preindl K,Manser P,Wick P,Marko D,Buerki-Thurnherr T

    更新日期:2019-10-01 00:00:00

  • Daily Walking among Commuters: A Cross-Sectional Study of Associations with Residential, Work, and Regional Accessibility in Melbourne, Australia (2012-2014).

    abstract:BACKGROUND:Most research on walking for transport has focused on the walkability of residential neighborhoods, overlooking the contribution of places of work/study and the ease with which destinations outside the immediate neighborhood can be accessed, referred to as regional accessibility. OBJECTIVES:We aimed to exam...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP3395

    authors: Barr A,Simons K,Mavoa S,Badland H,Giles-Corti B,Scheurer J,Korevaar E,Stewart J,Bentley R

    更新日期:2019-09-01 00:00:00

  • Mortality Risk and Fine Particulate Air Pollution in a Large, Representative Cohort of U.S. Adults.

    abstract:BACKGROUND:Evidence indicates that air pollution contributes to cardiopulmonary mortality. There is ongoing debate regarding the size and shape of the pollution–mortality exposure–response relationship. There are also growing appeals for estimates of pollution–mortality relationships that use public data and are based ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP4438

    authors: Pope CA 3rd,Lefler JS,Ezzati M,Higbee JD,Marshall JD,Kim SY,Bechle M,Gilliat KS,Vernon SE,Robinson AL,Burnett RT

    更新日期:2019-07-01 00:00:00

  • Metabolomics Profiling before, during, and after the Beijing Olympics: A Panel Study of Within-Individual Differences during Periods of High and Low Air Pollution.

    abstract:BACKGROUND:The metabolome is a collection of exogenous chemicals and metabolites from cellular processes that may reflect the body's response to environmental exposures. Studies of air pollution and metabolomics are limited. OBJECTIVES:To explore changes in the human metabolome before, during, and after the 2008 Beiji...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP3705

    authors: Mu L,Niu Z,Blair RH,Yu H,Browne RW,Bonner MR,Fanter T,Deng F,Swanson M

    更新日期:2019-05-01 00:00:00

  • Association between Early Life Exposure to Air Pollution and Working Memory and Attention.

    abstract:BACKGROUND:Although previous studies have reported negative associations between exposure to air pollution and cognition, studies of the effects of prenatal and postnatal exposures in early childhood have been limited. OBJECTIVES:We sought to assess the role exposure to fine particulate matter ([Formula: see text]) du...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP3169

    authors: Rivas I,Basagaña X,Cirach M,López-Vicente M,Suades-González E,Garcia-Esteban R,Álvarez-Pedrerol M,Dadvand P,Sunyer J

    更新日期:2019-05-01 00:00:00

  • Let the "A" in WASH Stand for Air: Integrating Research and Interventions to Improve Household Air Pollution (HAP) and Water, Sanitation and Hygiene (WaSH) in Low-Income Settings.

    abstract:BACKGROUND:Research often suffers from overspecialization, a practice nurtured in academia and reinforced by funders. Indeed, investigators in household air pollution (HAP) and water, sanitation and hygiene (WaSH), working in poor parts of the world, rarely interact despite having similar training and using similar met...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP4752

    authors: Clasen T,Smith KR

    更新日期:2019-02-01 00:00:00

  • Atmospheric Dust, Early Cases, and Localized Meningitis Epidemics in the African Meningitis Belt: An Analysis Using High Spatial Resolution Data.

    abstract:BACKGROUND:Bacterial meningitis causes a high burden of disease in the African meningitis belt, with regular seasonal hyperendemicity and sporadic short, but intense, localized epidemics during the late dry season occurring at a small spatial scale [i.e., below the district level, in individual health centers (HCs)]. I...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2752

    authors: Woringer M,Martiny N,Porgho S,Bicaba BW,Bar-Hen A,Mueller JE

    更新日期:2018-09-01 00:00:00

  • Traffic-Related Air Pollution, APOEε4 Status, and Neurodevelopmental Outcomes among School Children Enrolled in the BREATHE Project (Catalonia, Spain).

    abstract:BACKGROUND:Traffic-related air pollution is emerging as a risk factor for Alzheimer's disease (AD) and impaired brain development. Individual differences in vulnerability to air pollution may involve the ε4 allele of Apolipoprotein E (APOE) gene, the primary genetic risk factor for AD. OBJECTIVE:We analyzed whether th...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2246

    authors: Alemany S,Vilor-Tejedor N,García-Esteban R,Bustamante M,Dadvand P,Esnaola M,Mortamais M,Forns J,van Drooge BL,Álvarez-Pedrerol M,Grimalt JO,Rivas I,Querol X,Pujol J,Sunyer J

    更新日期:2018-08-02 00:00:00

  • A Prospective Cohort Study of Adolescents' Memory Performance and Individual Brain Dose of Microwave Radiation from Wireless Communication.

    abstract:BACKGROUND:The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions of adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with a higher cumulative RF-EMF brain dose in ad...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2427

    authors: Foerster M,Thielens A,Joseph W,Eeftens M,Röösli M

    更新日期:2018-07-23 00:00:00

  • Erratum: "Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture".

    abstract::[This corrects the article DOI: 10.1289/EHP2580.]. ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,已发布勘误

    doi:10.1289/EHP4002

    authors: Sagiv SK,Harris MH,Gunier RB,Kogut KR,Harley KG,Deardorff J,Bradman A,Holland N,Eskenazi B

    更新日期:2018-07-05 00:00:00

  • Spatial Modeling to Identify Sociodemographic Predictors of Hydraulic Fracturing Wastewater Injection Wells in Ohio Census Block Groups.

    abstract:BACKGROUND:Hydraulically fractured wells produce 2-14 million liters of wastewater, which may contain toxic and radioactive compounds. The wastewater is predominantly disposed of using Class II injection wells. OBJECTIVE:Our objective was to evaluate the relationship between sociodemographic characteristics and inject...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2663

    authors: Silva GS,Warren JL,Deziel NC

    更新日期:2018-06-27 00:00:00

  • Urinary Phthalate Metabolite Concentrations and Breast Cancer Incidence and Survival following Breast Cancer: The Long Island Breast Cancer Study Project.

    abstract:BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2083

    authors: Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

    更新日期:2018-04-26 00:00:00

  • Prenatal Exposure to DDT and Pyrethroids for Malaria Control and Child Neurodevelopment: The VHEMBE Cohort, South Africa.

    abstract:BACKGROUND:Although indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) and pyrethroids effectively controls malaria, it potentially increases human exposure to these insecticides. Previous studies suggest that prenatal exposure to these insecticides may impact human neurodevelopment. OBJECTIVES:...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2129

    authors: Eskenazi B,An S,Rauch SA,Coker ES,Maphula A,Obida M,Crause M,Kogut KR,Bornman R,Chevrier J

    更新日期:2018-04-06 00:00:00

  • Within-Day, Between-Day, and Between-Week Variability of Urinary Concentrations of Phenol Biomarkers in Pregnant Women.

    abstract:BACKGROUND:Toxicology studies have shown adverse effects of developmental exposure to industrial phenols. Evaluation in humans is challenged by potentially marked within-subject variability of phenol biomarkers in pregnant women, which is poorly characterized. OBJECTIVES:We aimed to characterize within-day, between-da...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1994

    authors: Vernet C,Philippat C,Calafat AM,Ye X,Lyon-Caen S,Siroux V,Schisterman EF,Slama R

    更新日期:2018-03-16 00:00:00

  • Erratum: "Estimated Changes in Life Expectancy and Adult Mortality Resulting from Declining PM2.5 Exposures in the Contiguous United States: 1980-2010".

    abstract::[This corrects the article DOI: https://doi.org/10.1289/EHP507.]. ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,已发布勘误

    doi:10.1289/EHP3422

    authors: Fann N,Kim SY,Olives C,Sheppard L

    更新日期:2018-02-20 00:00:00

  • Cadmium-Associated Differential Methylation throughout the Placental Genome: Epigenome-Wide Association Study of Two U.S. Birth Cohorts.

    abstract:BACKGROUND:Cadmium (Cd) is a ubiquitous environmental toxicant that can accumulate in the placenta during pregnancy, where it may impair placental function and affect fetal development. OBJECTIVES:We aimed to investigate Cd-associated variations in placental DNA methylation (DNAM) and associations with gene expression...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2192

    authors: Everson TM,Punshon T,Jackson BP,Hao K,Lambertini L,Chen J,Karagas MR,Marsit CJ

    更新日期:2018-01-22 00:00:00

  • Air Pollution and Performance-Based Physical Functioning in Dutch Older Adults.

    abstract:BACKGROUND:Functional limitations are a major cause for needing care and institutionalization among older adults. Exposure to air pollution has been suggested to be associated with increased functional limitations in older people. OBJECTIVE:Our objective was to assess the association between air pollution and physical...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2239

    authors: de Zwart F,Brunekreef B,Timmermans E,Deeg D,Gehring U

    更新日期:2018-01-19 00:00:00

  • A Web-Based System for Bayesian Benchmark Dose Estimation.

    abstract:BACKGROUND:Benchmark dose (BMD) modeling is an important step in human health risk assessment and is used as the default approach to identify the point of departure for risk assessment. A probabilistic framework for dose-response assessment has been proposed and advocated by various institutions and organizations; ther...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1289

    authors: Shao K,Shapiro AJ

    更新日期:2018-01-11 00:00:00

  • Long-Term Exposure to Transportation Noise in Relation to Development of Obesity—a Cohort Study.

    abstract:BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1910

    authors: Pyko A,Eriksson C,Lind T,Mitkovskaya N,Wallas A,Ögren M,Östenson CG,Pershagen G

    更新日期:2017-11-20 00:00:00

  • Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men.

    abstract:BACKGROUND:Cohort studies in North America and western Europe have reported increased risk of mortality associated with long-term exposure to fine particles (PM2.5), but to date, no such studies have been reported in China, where higher levels of exposure are experienced. OBJECTIVES:We estimated the association betwee...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1673

    authors: Yin P,Brauer M,Cohen A,Burnett RT,Liu J,Liu Y,Liang R,Wang W,Qi J,Wang L,Zhou M

    更新日期:2017-11-07 00:00:00

  • Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.

    abstract:BACKGROUND:The damaging effects of exposure to environmental toxicants differentially affect genetically distinct individuals, but the mechanisms contributing to these differences are poorly understood. Genetic variation affects the establishment of the gene regulatory landscape and thus gene expression, and we hypothe...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1937

    authors: Chappell GA,Israel JW,Simon JM,Pott S,Safi A,Eklund K,Sexton KG,Bodnar W,Lieb JD,Crawford GE,Rusyn I,Furey TS

    更新日期:2017-10-16 00:00:00

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