The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex.

abstract：:Artistic ability and creativity are defining characteristics of human behavior. Behavioral neurology, as a specialty, believes that even the most complex behaviors can be modeled and understood as the summation of smaller cognitive functions. Literature from individuals with specific brain lesions has helped to map ou...

journal_title：Progress in brain research

authors： Miller ZA,Miller BL

更新日期：2013-01-01 00:00:00

abstract：:Oxidative stress is known to play a key role in the initiation and promotion of the neurodegeneration that characterizes the pathogenesis of Alzheimer disease (AD). An accumulation of redox active transition metals, including iron and copper, is likely a major generator of reactive oxidative species and other free rad...

journal_title：Progress in brain research

authors： Liu G,Men P,Perry G,Smith MA

更新日期：2009-01-01 00:00:00

abstract：:Schwann cells (SCs), when implanted in the injured spinal cord, support regeneration of axons, myelinate or ensheathe regenerated axons in a normal way, reduce cyst formation in the injured tissue, reduce secondary damage of tissue around the initial injury site, and modestly improve limb movements. If SC transplantat...

journal_title：Progress in brain research

authors： Wiliams RR,Bunge MB

更新日期：2012-01-01 00:00:00

abstract：:Evidence for a non-monosynaptic Ia excitation of wrist flexor and quadriceps motoneurones (MNs) in man has been provided while using two independent methods: construction of post-stimulus time histograms (PSTHs) of voluntarily activated motor units and the spatial facilitation of the H-reflex. This non-monosynaptic Ia...

journal_title：Progress in brain research

authors： Pierrot-Deseilligny E

更新日期：1989-01-01 00:00:00

abstract：:Immunoreactive oxytocin (OXT) detected in extracts of human coeliac ganglia and nn. vagi was characterized by high-performance liquid chromatography (HPLC). HPLC/RIA examinations demonstrated that a major part of the immunoreactive material in both investigated areas co-eluted with a reference synthetic OXT, but in th...

journal_title：Progress in brain research

authors： Vecsernyés M,Jójárt I,Jójárt J,Laczi F

更新日期：1992-01-01 00:00:00

abstract：:Fatigue is considered to be an important and frequent factor in motivation problems. However, this term lacks clinical and pathophysiological validity. Semantic precision has to be improved. Lack of drive and tiredness with increased sleepiness as observed in fatigue in the context of inflammatory and immunological pr...

journal_title：Progress in brain research

authors： Hegerl U,Ulke C

更新日期：2016-01-01 00:00:00

abstract：:The epileptologically informed in-depth analysis of auto- and heteroanamnestic historical sources supports the hypothesis that Hector Berlioz (1803-1869) might have suffered from a photosensitive idiopathic generalized epilepsy syndrome with absences, absence status, myoclonic seizures, and bilateral tonic-clonic seiz...

journal_title：Progress in brain research

authors： Altenmüller DM

更新日期：2015-01-01 00:00:00

abstract：:Concerted efforts are realizing cell-based therapy for Parkinson's disease (PD). In this chapter, I describe efforts at the Center for iPS Cell Research and Application (CiRA), Kyoto University. These efforts use induced pluripotent stem cells (iPSCs) as donor cells. The iPSCs were established as human leukocyte antig...

journal_title：Progress in brain research

authors： Takahashi J

更新日期：2017-01-01 00:00:00

abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...

journal_title：Progress in brain research

authors： Shefchyk SJ

更新日期：2002-01-01 00:00:00

abstract：:The quantitative autoradiographic method with L-(35S)methionine was applied to investigate the effect of chronic dehydration on rates of protein synthesis in circumventricular organs (CVOs). Water deprivation for 1, 2 and 3 days causes progressive increases of protein synthesis in the subfornical organ (SFO), the area...

journal_title：Progress in brain research

authors： Lepetit P,Grange E,Gay N,Bobillier P

更新日期：1992-01-01 00:00:00

abstract：:Activated microglia release a number of substances, the specific cocktail released depending on the stimulus. Many of the substances released by microglia also serve to activate them, suggesting the presence of a number of autocrine/paracrine loops. Because of the low density of microglia present in the normal brain, ...

journal_title：Progress in brain research

authors： Pocock JM,Liddle AC

更新日期：2001-01-01 00:00:00

abstract：:A dense serotonin (5-HT)-containing projection to the superficial layers of the superior colliculus (SC) has been demonstrated in diverse mammalian species, but how 5-HT may affect visual signals within these laminae is largely unknown. This study undertook to investigate the distribution of 2 types of 5-HT receptors ...

journal_title：Progress in brain research

authors： Mooney RD,Huang X,Shi MY,Bennett-Clarke CA,Rhoades RW

更新日期：1996-01-01 00:00:00

abstract：:Over the past three decades, developmental neurobiologists have made tremendous progress in defining basic principles of brain development. This work has changed the way we think about how brains develop. Thirty years ago, the dominant model was strongly deterministic. The relationship between brain and behavioral dev...

journal_title：Progress in brain research

authors： Stiles J

更新日期：2011-01-01 00:00:00

abstract：:The hippocampus is crucial for the consolidation of new declarative long-term memories. Genetic and behavioral experimentation have revealed that several protein kinases are critical for the formation of hippocampus-dependent long-term memories. Cyclic-AMP dependent protein kinase (PKA) is a serine-threonine kinase th...

journal_title：Progress in brain research

authors： Abel T,Nguyen PV

更新日期：2008-01-01 00:00:00

abstract：:The ability to form tenable hypotheses regarding the neurobiological basis of normative functions as well as mechanisms underlying neurodegenerative and neuropsychiatric disorders is often limited by the highly complex brain circuitry and the cellular and molecular mosaics therein. The brain is an intricate structure ...

journal_title：Progress in brain research

authors： Ginsberg SD,Mirnics K

更新日期：2006-01-01 00:00:00

abstract：:The Tibetan Buddhist classification of mind, its divisions and the system of meditation practices aimed at achieving ideal states of being are a complex presentation of psychological, behavioral and spiritual concepts and processes that demand thorough understanding before assessing their value and outcome (Yeshe, 199...

journal_title：Progress in brain research

authors： Rapgay L,Rinpoche VL,Jessum R

更新日期：2000-01-01 00:00:00

abstract：:The identification of several mutations causing familial forms of Parkinson's disease (PD) has led to the creation of multiple lines of mice expressing similar genetic alterations. These models present a unique opportunity for understanding pathophysiological mechanisms leading to PD in a mammalian brain and provide m...

journal_title：Progress in brain research

authors： Magen I,Chesselet MF

更新日期：2010-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00

abstract：:Converging evidence from both human and animal studies has highlighted the pervasive role of two neuropeptides, oxytocin (OXT) and arginine vasopressin (AVP), in mammalian social behaviours. Recent molecular genetic studies of the human arginine vasopressin 1a (AVPR1a) and oxytocin (OXTR) receptors have strengthened t...

journal_title：Progress in brain research

authors： Israel S,Lerer E,Shalev I,Uzefovsky F,Reibold M,Bachner-Melman R,Granot R,Bornstein G,Knafo A,Yirmiya N,Ebstein RP

更新日期：2008-01-01 00:00:00

abstract：:Since the discovery of nerve growth factor (NGF) in the 1950s and brain-derived neurotrophic factor (BDNF) in the 1980s, a great deal of evidence has mounted for the roles of neurotrophins (NGF; BDNF; neurotrophin-3, NT-3; and neurotrophin-4/5, NT-4/5) in development, physiology, and pathology. BDNF in particular has ...

journal_title：Progress in brain research

authors： Binder DK

更新日期：2007-01-01 00:00:00

abstract：:Nerve growth factor (NGF) is required for the survival of developing sympathetic and sensory neurons. In the absence of NGF, these neurons undergo protein synthesis-dependent apoptosis. Ten years have gone by since the first reports of specific genes being upregulated during NGF deprivation-induced cell death. Over th...

journal_title：Progress in brain research

authors： Freeman RS,Burch RL,Crowder RJ,Lomb DJ,Schoell MC,Straub JA,Xie L

更新日期：2004-01-01 00:00:00

abstract：:This chapter summarizes the most recent data on the use of the somatostatin analogues (SSAs), octreotide (OCT) and lanreotide for the treatment of patients with pituitary and neuroendocrine tumors (NETs). These two analogues have a high affinity for somatostatin receptor (SSR) sub-types 2 and 5. The major indications ...

journal_title：Progress in brain research

authors： Colao A,Faggiano A,Pivonello R

更新日期：2010-01-01 00:00:00

abstract：:Partly due to the failure of anthropology to productively engage the fields of psychology and neuroscience, investigations in cultural neuroscience have occurred largely without the active involvement of anthropologists or anthropological theory. Dramatic advances in the tools and findings of social neuroscience have ...

journal_title：Progress in brain research

authors： Brown RA,Seligman R

更新日期：2009-01-01 00:00:00

abstract：:This chapter reviews the neurological phenotype of Down syndrome (DS) in early development, childhood, and aging. Neuroanatomic abnormalities in DS are manifested as aberrations in gross brain structure as well as characteristic microdysgenetic changes. As the result of these morphological abnormalities, brain circuit...

journal_title：Progress in brain research

authors： Lott IT

更新日期：2012-01-01 00:00:00

abstract：:Retinal ganglion cell axons within the globe are functionally specialized being richly provided with many mitochondria. The mitochondria produce the high energy requirement for nerve conduction in the unmyelinated part of the ganglion cell axons. We have proposed that in the initiation of glaucoma, an alteration in th...

journal_title：Progress in brain research

authors： Osborne NN

更新日期：2008-01-01 00:00:00

abstract：:Motor control of different segments of the body with multiple degrees of freedom appears to be coordinated by utilizing preferred axes of motor activity. This hypothesis may also be applied to vestibular control of posture. To explore this question we studied the anatomical relationship between the head and the cervic...

journal_title：Progress in brain research

authors： Vidal PP,Wang DH,Graf W,de Waele C

更新日期：1993-01-01 00:00:00

abstract：:The rat subcommissural organ (SCO), which forms the roof of the third ventricle is an adequate model to study certain mechanisms of neuron-glia interactions in vivo. The ependymocytes, the main component of the SCO, have a glial origin. They possess particular phenotypic characteristics: they accumulate [3H]GABA by a ...

journal_title：Progress in brain research

authors： Didier-Bazes M,Chouaf L,Hardin H,Aguera M,Voutsinos B,Belin MF

更新日期：1992-01-01 00:00:00

abstract：:Local recurrent connections endow the cerebellar cortex with an intrinsic dynamics. We performed computer simulations to predict the frequency bands of the oscillations that will most likely emerge. Feedback inhibition from the Golgi to the granule cells induced 10-50 Hz oscillations, the period at resonance being app...

journal_title：Progress in brain research

authors： Maex R,De Schutter E

更新日期：2005-01-01 00:00:00

abstract：:Human and nonhuman primates predictively use smooth pursuit and saccades to track visual targets that move in a fronto-parallel plane. This behaviour is believed to be facilitated by short-term memory of the target motion and/or an efference copy of the subject's motor effort. Subjects in our experiments tracked dicho...

journal_title：Progress in brain research

authors： Fu P,Chang R,O'Beirne K,King WM

更新日期：2008-01-01 00:00:00

abstract：:The recent increase in the frequency and intensity of killer heat waves across the globe has aroused worldwide medical attention to exploring therapeutic strategies to attenuate heat-related morbidity and/or mortality. Death due to heat-related illnesses often exceeds >50% of heat victims. Those who survive are crippl...

journal_title：Progress in brain research

authors： Sharma HS

更新日期：2007-01-01 00:00:00