Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease.

abstract：:The chapter reviews a classical Indian model of consciousness found in the Abhidhamma, a collection of seven treatises in the Pali Canon Tipitaka. The model was based on observations made during advanced vipassana practice, a first-person method taught by the Buddha. The climax of the model consists in the elucidation...

journal_title：Progress in brain research

authors： Banerjee R

更新日期：2008-01-01 00:00:00

abstract：:This chapter describes current findings from the research into postoperative cognitive dysfunction (POCD) following cardiac and non-cardiac surgery in older adults. The evidence suggests that a significant proportion of patients show POCD in the early weeks following surgery and anesthesia. Specific domains of cogniti...

journal_title：Progress in brain research

authors： Caza N,Taha R,Qi Y,Blaise G

更新日期：2008-01-01 00:00:00

abstract：:Antidepressants are commonly prescribed for tinnitus. Research thus far provides some support for that treatment, but the literature also raises concerns because tinnitus is a side effect of antidepressant medication. In this chapter, four published double blind placebo-controlled trials of antidepressants for tinnitu...

journal_title：Progress in brain research

authors： Robinson S

更新日期：2007-01-01 00:00:00

abstract：:When discrepant stimuli are presented to each eye and fusion is impossible, perception spontaneously oscillates between the two patterns (binocular rivalry). Functional MRI (fMRI) research identified a frontoparietal network in the right hemisphere associated with perceptual transitions, and it has been proposed that ...

journal_title：Progress in brain research

authors： Valle-Inclán F,Gallego E

更新日期：2006-01-01 00:00:00

abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...

journal_title：Progress in brain research

authors： Shefchyk SJ

更新日期：2002-01-01 00:00:00

abstract：:The idea of the dentate gyrus as a gate or filter at the entrance to the hippocampus, blocking or filtering incoming excitation from the entorhinal cortex, has been an intriguing one. Here we review the historical development of the idea, and discuss whether it may be possible to be more specific in defining this gate...

journal_title：Progress in brain research

authors： Hsu D

更新日期：2007-01-01 00:00:00

abstract：:The arts can provide unique ways for determining how people not directly involved in medicine were viewing and informing others about physical and mental disorders. With operas, one need only think about how various perturbations of madness have been portrayed. Somnambulism has long been a particularly perplexing diso...

journal_title：Progress in brain research

authors： Finger S,Sironi VA,Riva MA

更新日期：2015-01-01 00:00:00

abstract：:Results reported here confirm and extend those of early retrograde transport studies of the brainstem in the rat and cat. This study demonstrates substantial and multiple afferent projections to the cat locus coeruleus arising from neurons containing acetylcholine, serotonin, norepinephrine, epinephrine, dopamine, his...

journal_title：Progress in brain research

authors： Sakai K

更新日期：1991-01-01 00:00:00

abstract：:Various growth factors are present in the hippocampal formation and appear responsible for the prominent plasticity of this brain area. Although hormone-like growth-promoting polypeptides are the best known, recent studies emphasize the importance in the growth response of molecules such as laminin proteoglycans, neur...

journal_title：Progress in brain research

authors： Nieto-Sampedro M,Bovolenta P

更新日期：1990-01-01 00:00:00

abstract：:Noradrenergic LC neurons appear to be relatively unique in the brain, being unsurpassed in the divergence and ubiquity of their projections through the central nervous system. In this regard, they share certain characteristics with peripheral noradrenaline neurons of the sympathetic nervous system. As such they would ...

journal_title：Progress in brain research

authors： Jones BE

更新日期：1991-01-01 00:00:00

abstract：:Network oscillations are proposed to provide the framework for the ongoing neural computations of the brain. Thus, an important aspect of understanding the functional roles of various cell classes in the brain is to understand the relationship of cellular activity to the ongoing oscillations. While many studies have c...

journal_title：Progress in brain research

authors： Henze DA,Buzsáki G

更新日期：2007-01-01 00:00:00

abstract：:The nervous system can generate rhythms of various frequencies; on the low-frequency side, we have the circuits regulating circadian rhythms with a 24-h period, while on the high-frequency side we have the motor circuits that underlie flight in a hummingbird. Given the ubiquitous nature of rhythms, it is surprising th...

journal_title：Progress in brain research

authors： Saint-Amant L

更新日期：2010-01-01 00:00:00

abstract：:This chapter summarizes the most recent data on the use of the somatostatin analogues (SSAs), octreotide (OCT) and lanreotide for the treatment of patients with pituitary and neuroendocrine tumors (NETs). These two analogues have a high affinity for somatostatin receptor (SSR) sub-types 2 and 5. The major indications ...

journal_title：Progress in brain research

authors： Colao A,Faggiano A,Pivonello R

更新日期：2010-01-01 00:00:00

abstract：:Fatigue is considered to be an important and frequent factor in motivation problems. However, this term lacks clinical and pathophysiological validity. Semantic precision has to be improved. Lack of drive and tiredness with increased sleepiness as observed in fatigue in the context of inflammatory and immunological pr...

journal_title：Progress in brain research

authors： Hegerl U,Ulke C

更新日期：2016-01-01 00:00:00

abstract：:Based on a review of anatomical and physiological findings, we suggest that the hippocampus may be viewed as a positive feedback device (autoassociator), which is capable of modifying the activity of the neocortical neurons. We examine the three-dimensional organization of evoked and spontaneous physiological patterns...

journal_title：Progress in brain research

authors： Buzsáki G,Chen LS,Gage FH

更新日期：1990-01-01 00:00:00

abstract：:Otoacoustic emissions can be used to study cochlear function in an objective, non-invasive and rapid manner. These and other desirable features of emissions have inspired a significant amount of investigation into the practicalities of utilizing evoked emissions as clinical tests of hearing. Variables which affect the...

journal_title：Progress in brain research

authors： Lonsbury-Martin BL,Whitehead ML,Martin GK

更新日期：1993-01-01 00:00:00

abstract：:The management of urinary tract dysfunction is crucial for the health and well-being of people with spinal cord injury. Devices, specifically catheters, play an important role in the daily regime of bladder management for most people with spinal cord injury. However, the high incidence of complications associated with...

journal_title：Progress in brain research

authors： Gaunt RA,Prochazka A

更新日期：2006-01-01 00:00:00

abstract：:The aim of this experiment was to investigate whether there were differences in decision-making skills between different age groups (Under 16, 18 and 23) of elite academy footballers on a video-based task of real-life football scenarios. It also explored the relationship between individual performance on the task and ...

journal_title：Progress in brain research

authors： Farahani J,Soltani P,Rezlescu C

更新日期：2020-01-01 00:00:00

abstract：:Object recognition and visual attention are tightly linked processes in human perception. Over the last three decades, many models have been suggested to explain these two processes and their interactions, and in some cases these models appear to contradict each other. We suggest a unifying framework for object recogn...

journal_title：Progress in brain research

authors： Walther DB,Koch C

更新日期：2007-01-01 00:00:00

abstract：:Neurons in the midbrain superior colliculus (SC) have the ability to integrate information from different senses to profoundly increase their sensitivity to external events. This not only enhances an organism's ability to detect and localize these events, but to program appropriate motor responses to them. The surviva...

journal_title：Progress in brain research

authors： Stein BE,Rowland BA

更新日期：2011-01-01 00:00:00

abstract：:Over the past decade, hypothalamic circuits have been described that impact energy homeostasis in rodents and humans. Our drug development efforts for the treatment of obesity and the metabolic syndrome have largely focused on selected genetic and/or pharmacologically validated pathways. The translation of these pathw...

journal_title：Progress in brain research

authors： Van der Ploeg LH,Kanatani A,MacNeil D,Ming Fong T,Strack A,Nargund R,Guan XM

更新日期：2006-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:Immunoreactive oxytocin (OXT) detected in extracts of human coeliac ganglia and nn. vagi was characterized by high-performance liquid chromatography (HPLC). HPLC/RIA examinations demonstrated that a major part of the immunoreactive material in both investigated areas co-eluted with a reference synthetic OXT, but in th...

journal_title：Progress in brain research

authors： Vecsernyés M,Jójárt I,Jójárt J,Laczi F

更新日期：1992-01-01 00:00:00

abstract：:Human evolution was marked by an extraordinary increase in total brain size relative to body size. While it is certain that increased encephalization is an important factor contributing to the origin of our species-specific cognitive abilities, it is difficult to disentangle which aspects of human neural structure and...

journal_title：Progress in brain research

authors： Sherwood CC,Bauernfeind AL,Bianchi S,Raghanti MA,Hof PR

更新日期：2012-01-01 00:00:00

abstract：:When an object partially or completely disappears behind an occluding surface, a representation of that object persists. For example, fragments of no longer visible objects can serve as an input into mid-level constructive visual processes, interacting and integrating with currently visible portions to form perceptual...

journal_title：Progress in brain research

authors： McCarthy JD,Erlikhman G,Caplovitz GP

更新日期：2017-01-01 00:00:00

abstract：:In the target article, Hardy and colleagues provided an incisive analysis of retrospectively reported psychosocial factors associated with the development and careers of 32 former athletes from Olympic sports. They found that Super-Elite athletes ("serial" medal winners at major international championships, i.e., Worl...

journal_title：Progress in brain research

authors： Gucciardi DF

更新日期：2017-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00

abstract：:In our overview, we will attempt to justify the use of animal models and suggest that it is the only way to make the successive transitions between changes occurring at the molecular and cellular levels and changes at the level of behaviour in the intact organism. We will also stress the importance of criteria that ha...

journal_title：Progress in brain research

authors： Castellucci VF

更新日期：2008-01-01 00:00:00

abstract：:The ability to form tenable hypotheses regarding the neurobiological basis of normative functions as well as mechanisms underlying neurodegenerative and neuropsychiatric disorders is often limited by the highly complex brain circuitry and the cellular and molecular mosaics therein. The brain is an intricate structure ...

journal_title：Progress in brain research

authors： Ginsberg SD,Mirnics K

更新日期：2006-01-01 00:00:00

abstract：:An unresolved issue in visual motion perception is how distinct are the processes underlying 'first-order' and 'second-order' motion. The former is defined by spatio-temporal variations of luminance and the latter by spatio-temporal variations in other image attributes such as contrast or depth, for example. Using neu...

journal_title：Progress in brain research

authors： Vaina LM,Soloviev S

更新日期：2004-01-01 00:00:00