Abstract:
:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscles. These three efferent systems involved in the control of lower urinary tract function receive segmental sensory information from various visceral organs and the perineum, as well as inputs from supraspinal regions. Ascending and descending connections between the various spinal segments levels and supraspinal regions provide the reflex substrates participating in normal bladder continence and micturition reflexes. Many of the actions of descending and segmental reflexes are mediated by excitatory and inhibitory sacral spinal interneurons located within the region of the parasympathetic preganglionic autonomic neurons and the sphincter ventral horn motoneurons. This review will: (1) discuss the basic organization and spinal elements of the reflex pathways subserving continence and micturition; (2) describe features of the identified sacral interneuronal circuitry contributing to the control of the bladder and sphincter function; and (3) discuss how changes in the control of these reflex pathways and neurons may contribute to abnormal patterns of bladder and sphincter function commonly observed following spinal cord injury.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Shefchyk SJdoi
10.1016/s0079-6123(02)37008-0subject
Has Abstractpub_date
2002-01-01 00:00:00pages
71-82eissn
0079-6123issn
1875-7855pii
S0079-6123(02)37008-0journal_volume
137pub_type
杂志文章,评审abstract::The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(03)14404-4
更新日期:2004-01-01 00:00:00
abstract::The chapter reviews a classical Indian model of consciousness found in the Abhidhamma, a collection of seven treatises in the Pali Canon Tipitaka. The model was based on observations made during advanced vipassana practice, a first-person method taught by the Buddha. The climax of the model consists in the elucidation...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(07)68020-0
更新日期:2008-01-01 00:00:00
abstract::Nitric oxide (NO) is widespread in the nervous system and is thought to play a role in a variety of different neuronal functions, including learning and memory (see other chapters, this volume). A number of behavioral studies have indicated that NO is involved in several types of learning such as motor learning (Yanag...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)63206-9
更新日期:1998-01-01 00:00:00
abstract::Selective attention is an important aspect of brain function that we need in coping with the immense and constant barrage of sensory information. One model of attention (Feature Integration Theory) that suggests an early selection of spatial locations of objects via an attentional spotlight would also solve the 'bindi...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(01)34020-7
更新日期:2001-01-01 00:00:00
abstract::The effects of endogenous metabolites of the neuropeptide vasopressin (VP) in behavioural tests led to the hypothesis that VP metabolites have a more selective function than VP. In contrast to VP, no peripheral effects have been found thus far with VP metabolites and their function seems to be associated with memory-r...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)61591-5
更新日期:1998-01-01 00:00:00
abstract::Children with epilepsy are known to have high rates of mental health problems. The role of seizures in the development of these problems is not known primarily because of difficulties in separating the effects of seizures from the three other potential causal factors: (a) poor child and family response to the conditio...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(02)35039-8
更新日期:2002-01-01 00:00:00
abstract::Acute intermittent hypoxia (AIH) triggers a form of respiratory plasticity known as long-term facilitation (LTF), which is manifested as a progressive increase in respiratory motor activity that lasts for minutes to hours after the hypoxic stimulus is removed. Respiratory LTF has been reported in numerous animal model...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/B978-0-444-63488-7.00011-2
更新日期:2014-01-01 00:00:00
abstract::Quantitative models of the oculomotor plant and control of the saccadic eye movement system are presented in this chapter. Oculomotor plant models described here are linear, including a second-order model by Westheimer (1954), Bahill et al. (1980) and Enderle et al. (2000). The model of the saccade generator is initia...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(02)40040-4
更新日期:2002-01-01 00:00:00
abstract::The noradrenergic (NA) afferent projection to the cerebellar cortex, which originates mainly from the locus coeruleus (LC), may act on the target neurons by utilizing both alpha- and beta-adrenoceptors. Experiments performed in decerebrate cats have shown that unilateral injection into the vermal cortex of the cerebel...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/s0079-6123(08)63828-5
更新日期:1991-01-01 00:00:00
abstract::In the kidney, the actions of the antidiuretic hormone arginine vasopressin (AVP) renders the collecting duct highly permeable to water. This large increase in water permeability is largely due to the translocation of the water channel aquaporin-2 (AQP-2) from intracellular storage vesicles to the apical plasma membra...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(08)00444-5
更新日期:2008-01-01 00:00:00
abstract::Recent upsurge in research has uncovered distinct circuitries that regulate appetite, energy expenditure and fat accrual under the supervision of hormonal feedback signalling of adipocyte leptin and gastric ghrelin in the hypothalamic integration of energy homeostasis. A host of messenger molecules of diverse chemical...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(08)81002-3
更新日期:2010-01-01 00:00:00
abstract::The cellular and ionic mechanisms that generate the rhythm in central pattern generator (CPG) networks for simple movements are not well understood. Using vertebrate locomotion, respiration and mastication as exemplars, I describe four main principles of rhythmogenesis: (1) rhythmogenic ionic currents underlie all CPG...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/B978-0-444-53613-6.00014-9
更新日期:2010-01-01 00:00:00
abstract::Chronic epilepsy, as a consequence of status epilepticus, has been studied in animal models in order to analyze the cellular mechanisms responsible for the subsequent occurrence of spontaneous seizures. Status epilepticus, induced by either kainic acid or pilocarpine or by prolonged electrical stimulation, causes a ch...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(02)35007-6
更新日期:2002-01-01 00:00:00
abstract::Metabolic status varies predictably on a daily and seasonal basis in order to adapt to the cyclical environment. The hypothalamic circadian pacemaker of the suprachiasmatic nuclei (SCN) co-ordinates these metabolic cycles. Circadian timing is based upon a transcriptional/post-translational negative feedback loop invol...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)53015-8
更新日期:2006-01-01 00:00:00
abstract::We present results of a study of torsional eye movements evoked by earth-vertical accelerations along the subject's longitudinal axis. The earth-vertical stimulus leads to a gravito-inertial acceleration vector that changes magnitude but not direction. It can therefore be viewed as a dynamic change of the gravity leve...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/S0079-6123(08)00646-8
更新日期:2008-01-01 00:00:00
abstract::It was generally accepted by the early 1960s that proton beam radiosurgery was too complex and impractical. The need was seen for a new machine. The beam design had to be as good as a proton beam. It was also decided that a static design was preferable even if the evolution of that notion is no longer clear. Complex c...
journal_title:Progress in brain research
pub_type: 历史文章,杂志文章,评审
doi:10.1016/B978-0-444-63520-4.00007-7
更新日期:2014-01-01 00:00:00
abstract::The study of consciousness within cognitive neuroscience has been dominated in recent years by investigations originating from collaborations between neuroscientific investigators and Buddhist meditation practitioners. The results have been remarkable, particularly when quantitative and qualitative research methods ha...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/bs.pbr.2018.10.016
更新日期:2019-01-01 00:00:00
abstract::Elucidation of the molecular basis of mammalian circadian rhythms has progressed dramatically in recent years through the characterization of mouse mutants. With the implementation of numerous mouse genetics programs, comprehensive sets of mutations in genes affecting circadian output measures have been generated. Alt...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/B978-0-444-59427-3.00015-0
更新日期:2012-01-01 00:00:00
abstract::Predictive processes are widespread in the motor and sensory areas of the primate brain. They enable rapid computations despite processing delays and assist in resolving noisy, ambiguous input. Here we propose that the frontal eye field, a cortical area devoted to sensorimotor aspects of eye movement control, implemen...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/S0079-6123(08)00656-0
更新日期:2008-01-01 00:00:00
abstract::The complex migrations of neurons born in the dorsal neural tube of the isthmic and rhombomere l (rl) domains complicate the delineation of the cerebellar primordium. We show that Purkinje cells (P) are likely generated over a wide territory before gathering in the future cerebellar primordium under the developing ext...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(04)48003-0
更新日期:2005-01-01 00:00:00
abstract::Two cortical areas that crucially contribute to the generation and maintenance of smooth pursuit eye movements (SPEM) are the medial superior temporal area (MST) and the pursuit area of the frontal eye fields (FEF). They both project to the brainstem premotor structures via different parallel pathways. A special prope...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/S0079-6123(08)00636-5
更新日期:2008-01-01 00:00:00
abstract::This is a brief review of event-related brain potentials (ERPs) as indices of cortical information processing in conditions in which conscious perception of stimuli is supposed to be absent: sleep, coma, vegetative state, general anesthesia, neglect as well as presentation of subliminal or masked stimuli. Exogenous ER...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(05)50030-X
更新日期:2005-01-01 00:00:00
abstract::The aim of this chapter is to review recent literature describing how developments in cognition may contribute to age-related changes in emotional processes, specifically emotion regulation and emotion perception. In general, older adults are more likely than young adults to report feeling positive. Prominent conceptu...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/bs.pbr.2019.02.007
更新日期:2019-01-01 00:00:00
abstract::This chapter reviews research that focuses on the effects of emotionality of single words, and of simple phrases, on event-related brain potentials when these are presented visually in various tasks. In these studies, presentation of emotionally evocative language material has consistently elicited a late (c. 300-600 ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)56009-1
更新日期:2006-01-01 00:00:00
abstract::Neuronal nitric oxide synthase (nNOS) participate in a variety of physiologic and pathologic processes in the nervous system. nNOS was originally felt to be a constitutively expressed enzyme, but recent observations suggest that its levels are dynamically controlled in response to neuronal development, plasticity and ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)63196-9
更新日期:1998-01-01 00:00:00
abstract::Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression (CSD) is a wave of near-complete depolarization of neurons and glial cells that slowly propagates along the cortex creating the perception of aura. Evidence suggests that CSD can trigger migraine headache....
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/bs.pbr.2020.05.009
更新日期:2020-01-01 00:00:00
abstract::The recent increase in the frequency and intensity of killer heat waves across the globe has aroused worldwide medical attention to exploring therapeutic strategies to attenuate heat-related morbidity and/or mortality. Death due to heat-related illnesses often exceeds >50% of heat victims. Those who survive are crippl...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)62010-4
更新日期:2007-01-01 00:00:00
abstract::Partly due to the failure of anthropology to productively engage the fields of psychology and neuroscience, investigations in cultural neuroscience have occurred largely without the active involvement of anthropologists or anthropological theory. Dramatic advances in the tools and findings of social neuroscience have ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(09)17803-2
更新日期:2009-01-01 00:00:00
abstract::Ocular dominance plasticity may be the paradigmatic in vivo model of activity-dependent plasticity. More than four decades of intense research has delineated the network-level rules that govern synaptic change in this model. The recent characterization of a murine model for ocular dominance plasticity has facilitated ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(04)47008-3
更新日期:2005-01-01 00:00:00
abstract::Glaucoma is an age-related neurodegenerative disease that begins at the onset of aging. In this disease, there is an involvement of the immune system and therefore of the microglia. The purpose of this study is to evaluate the microglial activation using a mouse model of ocular hypertension (OHT) at the onset of aging...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/bs.pbr.2020.05.024
更新日期:2020-01-01 00:00:00