Abstract:
:Local recurrent connections endow the cerebellar cortex with an intrinsic dynamics. We performed computer simulations to predict the frequency bands of the oscillations that will most likely emerge. Feedback inhibition from the Golgi to the granule cells induced 10-50 Hz oscillations, the period at resonance being approximately equal to four times the maximum conduction delay generated along the parallel-fiber connections from granule to Golgi cells. In the molecular layer, the interneurons tended to induce fast oscillations (100-250 Hz), having a period equal to about four times the delay over their reciprocal synaptic connections. Finally, although the presence of lateral inhibition among the Purkinje cells has not been firmly established, reciprocal Purkinje-cell synapses are predicted to transform the cerebellar cortex into a potential temporal integrator.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Maex R,De Schutter Edoi
10.1016/S0079-6123(04)48015-7subject
Has Abstractpub_date
2005-01-01 00:00:00pages
181-8eissn
0079-6123issn
1875-7855pii
S0079612304480157journal_volume
148pub_type
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