Genetically encoded molecular tools for light-driven silencing of targeted neurons.

abstract：:John Bell, brother-surgeon of Charles Bell, was, like Charles, an outstanding surgeon and a good artist. John was one of the few who illustrated his work with their own drawings in the days before audiovisual aids were available and without the benefit of reliable drawing aids, photography and computer-aided design. C...

journal_title：Progress in brain research

authors： Gardner-Thorpe C

更新日期：2013-01-01 00:00:00

abstract：:Swallowing is an essential function in our daily life; nevertheless, stroke or other neurodegenerative diseases can cause the malfunction of swallowing function, ie, dysphagia. The objectives of this review are to understand the neural and cortical basis of swallowing and tongue, and review the latest techniques on th...

journal_title：Progress in brain research

authors： Yang H,Ang KK,Wang C,Phua KS,Guan C

更新日期：2016-01-01 00:00:00

abstract：:Orexin, also known as hypocretin, is a hypothalamic neuropeptide important for mediation of arousal and sleep as well as feeding and energy homeostasis. Recent studies have indicated that orexin also plays a key role regulating motivation and reward associated with food intake and with drugs of abuse. Based on those f...

journal_title：Progress in brain research

authors： Di Sebastiano AR,Coolen LM

更新日期：2012-01-01 00:00:00

abstract：:In recent years the scientific community has come to appreciate that the early cortical representations for visually guided arm movements are probably coded in a visual frame, i.e. relative to retinal landmarks. While this scheme accounts for many behavioral and neurophysiological observations, it also poses certain p...

journal_title：Progress in brain research

authors： Henriques DY,Medendorp WP,Khan AZ,Crawford JD

更新日期：2002-01-01 00:00:00

abstract：:While the role of attention in selecting visual attributes is well acknowledged, relatively less is known about the mechanisms that facilitate the selection of actions during goal-directed behaviors. The notion of an executive attention has provided a particularly fruitful framework to understand how the brain coordin...

journal_title：Progress in brain research

authors： Sharika KM,Ray S,Murthy A

更新日期：2009-01-01 00:00:00

abstract：:Epileptic seizures cause dynamic, reversible changes in brain function and are often associated with loss of consciousness. Of all seizure types, absence seizures lead to the most selective deficits in consciousness, with relatively little motor or other manifestations. Impaired consciousness in absence seizures is no...

journal_title：Progress in brain research

authors： Blumenfeld H

更新日期：2005-01-01 00:00:00

abstract：:Results reported here confirm and extend those of early retrograde transport studies of the brainstem in the rat and cat. This study demonstrates substantial and multiple afferent projections to the cat locus coeruleus arising from neurons containing acetylcholine, serotonin, norepinephrine, epinephrine, dopamine, his...

journal_title：Progress in brain research

authors： Sakai K

更新日期：1991-01-01 00:00:00

abstract：:Neuroimaging studies of major depression have identified neurophysiological abnormalities in multiple areas of the prefrontal cortex (PFC), the amygdala, and related parts of the striatum and thalamus. Some of these abnormalities are mood state-dependent, and appear in regions where cerebral blood flow (CBF) increases...

journal_title：Progress in brain research

authors： Drevets WC

更新日期：2000-01-01 00:00:00

abstract：:Using alternatively labelled (-)-deprenyl (3H label in the ring and 14C in the propargyl group) the distribution of the compound was studied in 15 brain regions and the plasma of rats over a period of 96 h, after oral administration of 1.5 mg/kg of (-)-deprenyl. The compound is rapidly absorbed (within 15-30 min) from...

journal_title：Progress in brain research

authors： Magyar K,Lengyel J,Szatmári I,Gaál J

更新日期：1995-01-01 00:00:00

abstract：:Activated microglia release a number of substances, the specific cocktail released depending on the stimulus. Many of the substances released by microglia also serve to activate them, suggesting the presence of a number of autocrine/paracrine loops. Because of the low density of microglia present in the normal brain, ...

journal_title：Progress in brain research

authors： Pocock JM,Liddle AC

更新日期：2001-01-01 00:00:00

abstract：:This chapter describes current findings from the research into postoperative cognitive dysfunction (POCD) following cardiac and non-cardiac surgery in older adults. The evidence suggests that a significant proportion of patients show POCD in the early weeks following surgery and anesthesia. Specific domains of cogniti...

journal_title：Progress in brain research

authors： Caza N,Taha R,Qi Y,Blaise G

更新日期：2008-01-01 00:00:00

abstract：:Compensatory electromyographic (EMG) responses and several biomechanical parameters were studied following impulsive disturbance of the limbs during stance of human volunteers on a treadmill. Treadmill acceleration impulses were backwards or forwards directed, or their initial direction was reversed after 30 ms. Backw...

journal_title：Progress in brain research

authors： Dietz V,Horstmann GA,Berger W

更新日期：1989-01-01 00:00:00

abstract：:The complex migrations of neurons born in the dorsal neural tube of the isthmic and rhombomere l (rl) domains complicate the delineation of the cerebellar primordium. We show that Purkinje cells (P) are likely generated over a wide territory before gathering in the future cerebellar primordium under the developing ext...

journal_title：Progress in brain research

authors： Narboux-Nême N,Louvi A,Alexandre P,Wassef M

更新日期：2005-01-01 00:00:00

abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...

journal_title：Progress in brain research

authors： Shefchyk SJ

更新日期：2002-01-01 00:00:00

abstract：:Antidepressants are commonly prescribed for tinnitus. Research thus far provides some support for that treatment, but the literature also raises concerns because tinnitus is a side effect of antidepressant medication. In this chapter, four published double blind placebo-controlled trials of antidepressants for tinnitu...

journal_title：Progress in brain research

authors： Robinson S

更新日期：2007-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:Life expectancies have increased substantially in the last century, dramatically amplifying the proportion of individuals who will reach old age. As individuals age, cognitive ability declines, although the rate of decline differs amongst the forms of memory domains and for different individuals. Memory domains especi...

journal_title：Progress in brain research

authors： Conrad CD,Bimonte-Nelson HA

更新日期：2010-01-01 00:00:00

abstract：:The midbrain has been shown to contain crucial nuclei for the control of vertical and torsional eye movements. Recent studies in monkeys demonstrated that midbrain lesions also affect head movements during gaze saccades, but so far clinical reports on the matter have been missing. We measured 3D eye and head movements...

journal_title：Progress in brain research

authors： Kremmyda O,Glasauer S,Eggert T,Büttner U

更新日期：2008-01-01 00:00:00

abstract：:Spinal cord injury (SCI) typically damages the long axonal tracts of the spinal cord which results in permanent disability. However, regeneration of the injured spinal cord is approaching reality according to the advances in stem cell biology. Cell transplantation therapy holds potential to lead to recovery following ...

journal_title：Progress in brain research

authors： Nori S,Nakamura M,Okano H

更新日期：2017-01-01 00:00:00

abstract：:Postural instability and falls are common causes of morbidity and mortality in the second most prevalent neurodegenerative condition, Parkinson's disease (PD). Poor understanding of balance dysfunction in PD has hampered the development of novel therapeutic measures for postural instability and balance dysfunction. We...

journal_title：Progress in brain research

authors： Beylergil SB,Ozinga S,Walker MF,McIntyre CC,Shaikh AG

更新日期：2019-01-01 00:00:00

abstract：:This investigation was designed to study the role of muscarinic receptor subtypes in the cardiovascular responses elicited by microinjection of cholinergic agonists in the intermediate portion of the NTS, the VLPA and VLDA areas and the IML of the spinal cord. Microinjections of L-glutamate (1.77 nmol in 20-50 nl in 0...

journal_title：Progress in brain research

authors： Sapru HN

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:glaucoma is the leading cause of irreversible blindness all over the world. The degree of visual field loss accounts for the severity of the disease and represents the main clinical outcome of treatment for patients affected by glaucoma. The α2 agonists, like brimonidine, emerged in the 1960s as topical opht...

journal_title：Progress in brain research

authors： Scuteri D,Bagetta G,Nucci C,Aiello F,Cesareo M,Tonin P,Corasaniti MT

更新日期：2020-01-01 00:00:00

abstract：:Two cortical areas that crucially contribute to the generation and maintenance of smooth pursuit eye movements (SPEM) are the medial superior temporal area (MST) and the pursuit area of the frontal eye fields (FEF). They both project to the brainstem premotor structures via different parallel pathways. A special prope...

journal_title：Progress in brain research

authors： Nuding U,Ono S,Mustari MJ,Büttner U,Glasauer S

更新日期：2008-01-01 00:00:00

abstract：:Evidence for a non-monosynaptic Ia excitation of wrist flexor and quadriceps motoneurones (MNs) in man has been provided while using two independent methods: construction of post-stimulus time histograms (PSTHs) of voluntarily activated motor units and the spatial facilitation of the H-reflex. This non-monosynaptic Ia...

journal_title：Progress in brain research

authors： Pierrot-Deseilligny E

更新日期：1989-01-01 00:00:00

abstract：:When discrepant stimuli are presented to each eye and fusion is impossible, perception spontaneously oscillates between the two patterns (binocular rivalry). Functional MRI (fMRI) research identified a frontoparietal network in the right hemisphere associated with perceptual transitions, and it has been proposed that ...

journal_title：Progress in brain research

authors： Valle-Inclán F,Gallego E

更新日期：2006-01-01 00:00:00

abstract：:Neural transplantation has emerged as a possible therapy for Parkinson's disease (PD). Clinical studies performed during the 1990s, where dopaminergic neurons derived from the human embryonic brain were transplanted into striatum of patients with PD, provided proof-of-principle that long-lasting therapeutic benefits c...

journal_title：Progress in brain research

authors： Brundin P,Barker RA,Parmar M

更新日期：2010-01-01 00:00:00

abstract：:More than a decade ago, Goodale and Milner proposed that our perceptual experience of the world depends on visual processing that is fundamentally distinct from that mediating the moment-to-moment visual control of our actions. They mapped this distinction between vision-for-perception and vision-for-action onto the t...

journal_title：Progress in brain research

authors： Goodale MA,Króliczak G,Westwood DA

更新日期：2005-01-01 00:00:00

abstract：:Resting state functional connectivity (rsFC) evaluated by detecting temporal co-variation of BOLD signals across multiple brain regions undergoes three major changes following sleep deprivation that indicate the occurrence of sleep intrusions; a loss of integration within networks like the default mode network as well...

journal_title：Progress in brain research

authors： Chee MWL,Zhou J

更新日期：2019-01-01 00:00:00

abstract：:Various growth factors are present in the hippocampal formation and appear responsible for the prominent plasticity of this brain area. Although hormone-like growth-promoting polypeptides are the best known, recent studies emphasize the importance in the growth response of molecules such as laminin proteoglycans, neur...

journal_title：Progress in brain research

authors： Nieto-Sampedro M,Bovolenta P

更新日期：1990-01-01 00:00:00

abstract：:Motor control of different segments of the body with multiple degrees of freedom appears to be coordinated by utilizing preferred axes of motor activity. This hypothesis may also be applied to vestibular control of posture. To explore this question we studied the anatomical relationship between the head and the cervic...

journal_title：Progress in brain research

authors： Vidal PP,Wang DH,Graf W,de Waele C

更新日期：1993-01-01 00:00:00