Cholinergic mechanisms subserving cardiovascular function in the medulla and spinal cord.

abstract：:Gamma aminobutyric acid (GABA) is an inhibitor neurotransmitter that plays many important roles in the central nervous system. Because the half-life time of GABA is very short in vivo, GABA itself is not used for clinical practice. An analogue of GABA, baclofen, is an agonist of GABA-B receptor, and has very strong an...

journal_title：Progress in brain research

authors： Taira T

更新日期：2009-01-01 00:00:00

abstract：:Concerted efforts are realizing cell-based therapy for Parkinson's disease (PD). In this chapter, I describe efforts at the Center for iPS Cell Research and Application (CiRA), Kyoto University. These efforts use induced pluripotent stem cells (iPSCs) as donor cells. The iPSCs were established as human leukocyte antig...

journal_title：Progress in brain research

authors： Takahashi J

更新日期：2017-01-01 00:00:00

abstract：:Understanding how action perception, embodiment, and emotion interact is essential for advancing knowledge about how we perceive and interact with each other in a social world. One tool that has proved particularly useful in the past decade for exploring the relationship between perception, action, and affect is dance...

journal_title：Progress in brain research

authors： Kirsch LP,Cross ES

更新日期：2018-01-01 00:00:00

abstract：:Cognitive neuroscience is currently finding itself as a marketing trend in occupational science, particularly in terms of workplace assessment and measurement. However, the field has historically had little to do with occupational applications and has generally remained focused on the clinical and academic relevance o...

journal_title：Progress in brain research

authors： Williams H,Lewis J

更新日期：2020-01-01 00:00:00

abstract：:Recordings of spinal INs during a flexion/extension wrist task with an instructed delay period have shown directly that many spinal neurons modulate their rate during the preparatory period soon after a visual cue. The onset time and the relation between the delay period activity of spinal INs and the ensuing movement...

journal_title：Progress in brain research

authors： Prut Y,Perlmutter SI,Fetz EE

更新日期：2001-01-01 00:00:00

abstract：:Essential infantile esotropia (EIE) is often attributed to a primary disturbance within the visual cortex based upon the findings of monocular horizontal optokinetic asymmetry and correlative horizontal motion detection asymmetry. However, these physiologic aberrations conform to what would be observed if the visual c...

journal_title：Progress in brain research

authors： Brodsky MC

更新日期：2019-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:Ocular dominance plasticity may be the paradigmatic in vivo model of activity-dependent plasticity. More than four decades of intense research has delineated the network-level rules that govern synaptic change in this model. The recent characterization of a murine model for ocular dominance plasticity has facilitated ...

journal_title：Progress in brain research

authors： Taha SA,Stryker MP

更新日期：2005-01-01 00:00:00

abstract：:An essential component of the brain extracellular space is the extracellular matrix contributing to the spatial assembly of cells by binding cell-surface adhesion molecules, supporting cell migration, differentiation, and tissue development. The most interesting and complex functions of the central nervous system are ...

journal_title：Progress in brain research

authors： Morawski M,Filippov M,Tzinia A,Tsilibary E,Vargova L

更新日期：2014-01-01 00:00:00

abstract：:The interactions of the dendritically released neuropeptides vasopressin and oxytocin with co-released neuroactive substances such as opioids and nitric oxide are reviewed. Endogenous opioids regulate magnocellular neurons at the level of the supraoptic nucleus and the relationship of dendritically released peptides a...

journal_title：Progress in brain research

authors： Ludwig M,Sabatier N,Dayanithi G,Russell JA,Leng G

更新日期：2002-01-01 00:00:00

abstract：:Deficits in motivation are at the core of many neuropsychiatric disorders, including major depressive disorder (MDD). Research in MDD has been heavily focused on anhedonia and depression or negative/positive symptoms of depression, with less research attention focused on the dysregulation of motivational processes. Op...

journal_title：Progress in brain research

authors： Callaghan CK,Rouine J,O'Mara SM

更新日期：2018-01-01 00:00:00

abstract：:Life expectancies have increased substantially in the last century, dramatically amplifying the proportion of individuals who will reach old age. As individuals age, cognitive ability declines, although the rate of decline differs amongst the forms of memory domains and for different individuals. Memory domains especi...

journal_title：Progress in brain research

authors： Conrad CD,Bimonte-Nelson HA

更新日期：2010-01-01 00:00:00

abstract：:Over the past three decades, developmental neurobiologists have made tremendous progress in defining basic principles of brain development. This work has changed the way we think about how brains develop. Thirty years ago, the dominant model was strongly deterministic. The relationship between brain and behavioral dev...

journal_title：Progress in brain research

authors： Stiles J

更新日期：2011-01-01 00:00:00

abstract：:The role of the superior colliculus in attending and orienting to sensory stimuli is facilitated by the presence within this midbrain nucleus of superimposed maps of different sensory modalities. We have studied the steps involved in the development of topographically-aligned maps of visual and auditory space in the f...

journal_title：Progress in brain research

authors： King AJ,Schnupp JW,Carlile S,Smith AL,Thompson ID

更新日期：1996-01-01 00:00:00

abstract：:The success of axon regeneration in the adult mammalian brain depends on the presence of growth-permissive environmental conditions as well as on specific properties of the affected neurons. To investigate the relative contribution of extrinsic cues and intrinsic determinants to reparative processes we have investigat...

journal_title：Progress in brain research

authors： Rossi F,Bravin M,Buffo A,Fronte M,Savio T,Strata P

更新日期：1997-01-01 00:00:00

abstract：:Disrupted in Schizophrenia-1 (DISC1) is one of the most likely susceptibility genes for schizophrenia (SZ). DISC1 is being established as a hub protein with various functions in the pre- and postnatal development of the nervous system. Since generation of a knockout (KO) mouse has proved challenging, various alternati...

journal_title：Progress in brain research

authors： Jaaro-Peled H

更新日期：2009-01-01 00:00:00

abstract：:Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are c...

journal_title：Progress in brain research

authors： Mackey S,Kan KJ,Chaarani B,Alia-Klein N,Batalla A,Brooks S,Cousijn J,Dagher A,de Ruiter M,Desrivieres S,Feldstein Ewing SW,Goldstein RZ,Goudriaan AE,Heitzeg MM,Hutchison K,Li CS,London ED,Lorenzetti V,Luijten M,Mart

更新日期：2016-01-01 00:00:00

abstract：:For diagnostic purposes, a differentiation can be made between the locus coeruleus (LC) in normal brain and the LC, in senile dementia of the Alzheimer's type (SDAT) and Parkinson's disease (PD). The differentiation is based on findings concerning the morphological alterations of the TH-immunoreactive; neurons, on the...

journal_title：Progress in brain research

authors： Chan-Palay V

更新日期：1991-01-01 00:00:00

abstract：:The cognitive changes that occur with ageing are usually referred to as 'age-related cognitive decline'. The most pronounced changes may be found in the executive functions that require integrity of the prefrontal cortical circuitry. With age, sleep also changes profoundly, with more sleep fragmentation, earlier awake...

journal_title：Progress in brain research

authors： Altena E,Ramautar JR,Van Der Werf YD,Van Someren EJ

更新日期：2010-01-01 00:00:00

abstract：:Early intervention and environmental optimization have been central to management of Down syndrome (DS) and much of current treatment is still focused in strategies that involve early education plans. This approach has provided significant improvements for Down syndrome but it is not providing a full success. The disc...

journal_title：Progress in brain research

authors： Martínez Cué C,Dierssen M

更新日期：2020-01-01 00:00:00

abstract：:In the present contribution, the various functional interpretations concerning the putative function of the orbital prefrontal cortex are reviewed since this region and adjacent areas are considered the neural substrate of social behavior in general, and decision-making behavior in particular. This literature review r...

journal_title：Progress in brain research

authors： Volz KG,von Cramon DY

更新日期：2009-01-01 00:00:00

abstract：:The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy. The overall objective o...

journal_title：Progress in brain research

authors： Koivuniemi A,Wilks SJ,Woolley AJ,Otto KJ

更新日期：2011-01-01 00:00:00

abstract：:Orexin, also known as hypocretin, is a hypothalamic neuropeptide important for mediation of arousal and sleep as well as feeding and energy homeostasis. Recent studies have indicated that orexin also plays a key role regulating motivation and reward associated with food intake and with drugs of abuse. Based on those f...

journal_title：Progress in brain research

authors： Di Sebastiano AR,Coolen LM

更新日期：2012-01-01 00:00:00

abstract：:We developed a theoretical framework for studying coordination strategies in standing posture. The framework consists of a musculoskeletal model of the human lower extremity in the sagittal plane and a technique to visualize, geometrically, how constraints internal and external to the body affect movement. The set of ...

journal_title：Progress in brain research

authors： Kuo AD,Zajac FE

更新日期：1993-01-01 00:00:00

abstract：:A neural-network module with attractor dynamics has been shown recently to be robust to stochastic noise in external and internal signals, and to converge rapidly onto an output signal that is an unbiased and efficient representation of the environment. We suggest here a modular network architecture with attractor dyn...

journal_title：Progress in brain research

authors： Krouchev NI,Kalaska JF

更新日期：2007-01-01 00:00:00

abstract：:Impulsive testing, which accurately measures the gain of the vestibulo-ocular reflex (VOR) is mostly recorded from only one eye. We measured the horizontal VOR of both eyes in response to graded velocity head impulses in 14 normal subjects. VOR acceleration gains were similar for each eye in both directions at low acc...

journal_title：Progress in brain research

authors： Weber KP,Aw ST,Todd MJ,McGarvie LA,Pratap S,Curthoys IS,Halmagyi GM

更新日期：2008-01-01 00:00:00

abstract：:By blocking electrical activity in the cerebellar cortex the Purkinje cell dendrites become a uniform territory with a high density of spines all bearing the glutamate receptor delta2 subunit (GluRdelta2) and being mainly innervated by parallel fibers. Such a subunit, which is constitutively targeted specifically to t...

journal_title：Progress in brain research

authors： Cesa R,Strata P

更新日期：2005-01-01 00:00:00

abstract：:Unraveling the mysteries of consciousness, lost and regained, and perhaps even intervening so as to prompt recovery are advances for which neither the clinical nor the lay community are prepared. These advances will shake existing expectations about severe brain damage and will find an unprepared clinical context, per...

journal_title：Progress in brain research

authors： Fins JJ

更新日期：2005-01-01 00:00:00

abstract：:Follicular development and ovulation are strongly inhibited during lactation. Administration of a high dose of estrogen induces luteinizing hormone (LH) surges in ovariectomized lactating rats, suggesting that brain mechanisms regulating cyclic LH release remain intact in lactating mothers. On the other hand, tonic LH...

journal_title：Progress in brain research

authors： Tsukamura H,Maeda K

更新日期：2001-01-01 00:00:00

abstract：:Although visually responsive neurons predominate in the deep layers of the superior colliculus (SC), the majority of them also receive sensory inputs from nonvisual sources (i.e. auditory and/or somatosensory). Most of these 'multisensory' neurons are able to synthesize their cross-modal inputs and, as a consequence, ...

journal_title：Progress in brain research

authors： Stein BE,Jiang W,Wallace MT,Stanford TR

更新日期：2001-01-01 00:00:00