Gene models of schizophrenia: DISC1 mouse models.

abstract：:This chapter summarizes the most recent data on the use of the somatostatin analogues (SSAs), octreotide (OCT) and lanreotide for the treatment of patients with pituitary and neuroendocrine tumors (NETs). These two analogues have a high affinity for somatostatin receptor (SSR) sub-types 2 and 5. The major indications ...

journal_title：Progress in brain research

authors： Colao A,Faggiano A,Pivonello R

更新日期：2010-01-01 00:00:00

abstract：:The interactions of the dendritically released neuropeptides vasopressin and oxytocin with co-released neuroactive substances such as opioids and nitric oxide are reviewed. Endogenous opioids regulate magnocellular neurons at the level of the supraoptic nucleus and the relationship of dendritically released peptides a...

journal_title：Progress in brain research

authors： Ludwig M,Sabatier N,Dayanithi G,Russell JA,Leng G

更新日期：2002-01-01 00:00:00

abstract：:Cerebral malformations are best understood as abnormal tissue morphogenesis in the context of disorders of ontogenesis. In neuroembryology, the timing of onset and duration of abnormal genetic expression and neurodevelopmental processes are primordial and must always be assessed, regardless whether the dysgenesis is p...

journal_title：Progress in brain research

authors： Sarnat HB,Flores-Sarnat L

更新日期：2014-01-01 00:00:00

abstract：:The midbrain has been shown to contain crucial nuclei for the control of vertical and torsional eye movements. Recent studies in monkeys demonstrated that midbrain lesions also affect head movements during gaze saccades, but so far clinical reports on the matter have been missing. We measured 3D eye and head movements...

journal_title：Progress in brain research

authors： Kremmyda O,Glasauer S,Eggert T,Büttner U

更新日期：2008-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:The hippocampus is crucial for the consolidation of new declarative long-term memories. Genetic and behavioral experimentation have revealed that several protein kinases are critical for the formation of hippocampus-dependent long-term memories. Cyclic-AMP dependent protein kinase (PKA) is a serine-threonine kinase th...

journal_title：Progress in brain research

authors： Abel T,Nguyen PV

更新日期：2008-01-01 00:00:00

abstract：:The capacity to sustain high-intensity aerobic exercise is essential for endurance performance. Therefore, it is important to understand what is the factor limiting time to exhaustion (TTE) in healthy and fit adults. In Study 1, maximal voluntary cycling power (MVCP) was measured in 11 volunteers before and immediatel...

journal_title：Progress in brain research

authors： Staiano W,Bosio A,de Morree HM,Rampinini E,Marcora S

更新日期：2018-01-01 00:00:00

abstract：:The BBB is a target for some peptide signals, as demonstrated by our group for arginine-vasopressin (AVP) and atriopeptin (ANP). Peptide molecules contacting the luminal surface of endothelial cells interact with specific high-affinity binding sites. The minimal simple diffusion of peptide molecules across the layer o...

journal_title：Progress in brain research

authors： Ermisch A

更新日期：1992-01-01 00:00:00

abstract：:Oestrogens (E) influence the activity of oxytocin (OT) producing neurons and heighten the rate of transcription of the oxytocin receptor (OTR) gene. Working through synergistic activities of two different oestrogen receptors (ERs), likely gene duplication products, in the hypothalamus and amygdala, E supports social r...

journal_title：Progress in brain research

authors： Choleris E,Devidze N,Kavaliers M,Pfaff DW

更新日期：2008-01-01 00:00:00

abstract：:Much of the past research on how reward motivation and emotional information influence brain and behavior has been conducted separately. Recently, a few behavioral and brain imaging studies have investigated how reward and emotional information co-jointly impact brain and behavior. The present chapter reviews findings...

journal_title：Progress in brain research

authors： Padmala S,Sambuco N,Pessoa L

更新日期：2019-01-01 00:00:00

abstract：:Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are c...

journal_title：Progress in brain research

authors： Mackey S,Kan KJ,Chaarani B,Alia-Klein N,Batalla A,Brooks S,Cousijn J,Dagher A,de Ruiter M,Desrivieres S,Feldstein Ewing SW,Goldstein RZ,Goudriaan AE,Heitzeg MM,Hutchison K,Li CS,London ED,Lorenzetti V,Luijten M,Mart

更新日期：2016-01-01 00:00:00

abstract：:Selective attention is an important aspect of brain function that we need in coping with the immense and constant barrage of sensory information. One model of attention (Feature Integration Theory) that suggests an early selection of spatial locations of objects via an attentional spotlight would also solve the 'bindi...

journal_title：Progress in brain research

authors： Vidyasagar TR

更新日期：2001-01-01 00:00:00

abstract：:Several studies provided evidence for neuroendocrine dysregulations in adults with a history of child sexual abuse. This review focuses on neuroendocrine studies in sexually abused children and adolescents, dating from January 1, 1990 to January 1, 2007 and obtained from a systematic Medline Indexed literature search ...

journal_title：Progress in brain research

authors： Bicanic IA,Meijer M,Sinnema G,van de Putte EM,Olff M

更新日期：2008-01-01 00:00:00

abstract：:Spinal cord evoked potentials (SCEP) are good indicators of spinal cord function in health and disease. Disturbances in SCEP amplitudes and latencies during spinal cord monitoring predict spinal cord pathology following trauma. Treatment with neuroprotective agents preserves SCEP and reduces cord pathology after injur...

journal_title：Progress in brain research

authors： Sahib S,Sharma A,Menon PK,Muresanu DF,Castellani RJ,Nozari A,Lafuente JV,Bryukhovetskiy I,Tian ZR,Patnaik R,Buzoianu AD,Wiklund L,Sharma HS

更新日期：2020-01-01 00:00:00

abstract：:Research has outlined how self-regulation is crucial to the decision-making processes and pacing of endurance performance. There is evidence to suggest that executive function is implicated in self-regulatory processes, as the two are conceptually similar and share common brain regions such as the prefrontal cortex. T...

journal_title：Progress in brain research

authors： Hyland-Monks R,Cronin L,McNaughton L,Marchant D

更新日期：2018-01-01 00:00:00

abstract：:The noradrenergic (NA) afferent projection to the cerebellar cortex, which originates mainly from the locus coeruleus (LC), may act on the target neurons by utilizing both alpha- and beta-adrenoceptors. Experiments performed in decerebrate cats have shown that unilateral injection into the vermal cortex of the cerebel...

journal_title：Progress in brain research

authors： Andre P,d'Ascanio P,Pompeiano O

更新日期：1991-01-01 00:00:00

abstract：:Network oscillations are proposed to provide the framework for the ongoing neural computations of the brain. Thus, an important aspect of understanding the functional roles of various cell classes in the brain is to understand the relationship of cellular activity to the ongoing oscillations. While many studies have c...

journal_title：Progress in brain research

authors： Henze DA,Buzsáki G

更新日期：2007-01-01 00:00:00

abstract：:Alzheimer's disease (AD), the most common type of adult-onset dementia, is characterized by a variety of brain abnormalities, including degeneration of certain populations of nerve cells, alterations in the neuronal cytoskeleton, and the abnormal deposition of amyloid within brain parenchyma. Pathogenetic processes th...

journal_title：Progress in brain research

authors： Price DL,Koo EH,Sisodia SS,Martin LJ,Koliatsos VE,Muma NA,Walker LC,Cork LC

更新日期：1990-01-01 00:00:00

abstract：:The study of consciousness within cognitive neuroscience has been dominated in recent years by investigations originating from collaborations between neuroscientific investigators and Buddhist meditation practitioners. The results have been remarkable, particularly when quantitative and qualitative research methods ha...

journal_title：Progress in brain research

authors： Parker S

更新日期：2019-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most prevalent form of neurodegeneration; however, therapies to prevent or treat AD are inadequate. Amyloid-beta (Abeta) protein accrues in cortical senile plaques, one of the key neuropathological hallmarks of AD, and is elevated in brains of early onset AD patients in a small number o...

journal_title：Progress in brain research

authors： Lemere CA

更新日期：2009-01-01 00:00:00

abstract：:Since the discovery of nerve growth factor (NGF) in the 1950s and brain-derived neurotrophic factor (BDNF) in the 1980s, a great deal of evidence has mounted for the roles of neurotrophins (NGF; BDNF; neurotrophin-3, NT-3; and neurotrophin-4/5, NT-4/5) in development, physiology, and pathology. BDNF in particular has ...

journal_title：Progress in brain research

authors： Binder DK

更新日期：2007-01-01 00:00:00

abstract：:John Bell, brother-surgeon of Charles Bell, was, like Charles, an outstanding surgeon and a good artist. John was one of the few who illustrated his work with their own drawings in the days before audiovisual aids were available and without the benefit of reliable drawing aids, photography and computer-aided design. C...

journal_title：Progress in brain research

authors： Gardner-Thorpe C

更新日期：2013-01-01 00:00:00

abstract：:Unraveling the mysteries of consciousness, lost and regained, and perhaps even intervening so as to prompt recovery are advances for which neither the clinical nor the lay community are prepared. These advances will shake existing expectations about severe brain damage and will find an unprepared clinical context, per...

journal_title：Progress in brain research

authors： Fins JJ

更新日期：2005-01-01 00:00:00

abstract：:The following chapter offers an overview of results of experimental studies conducted among healthy individuals examining the effects of acute administration of Δ9-THC and other cannabinoids, alone or in combination, on brain function and behavior, also as a function of previous cannabis exposure. In light of their me...

journal_title：Progress in brain research

authors： Colizzi M,Bhattacharyya S

更新日期：2018-01-01 00:00:00

abstract：:The recent increase in the frequency and intensity of killer heat waves across the globe has aroused worldwide medical attention to exploring therapeutic strategies to attenuate heat-related morbidity and/or mortality. Death due to heat-related illnesses often exceeds >50% of heat victims. Those who survive are crippl...

journal_title：Progress in brain research

authors： Sharma HS

更新日期：2007-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:There has been substantial progress in our understanding of the hippocampus in the past 70 years. During this time, it has become clear that the hippocampus is not an olfactory-related structure alone, but plays critical roles in other functions that do not necessarily depend on olfaction, such as learning and memory....

journal_title：Progress in brain research

authors： Seress L

更新日期：2007-01-01 00:00:00

abstract：:This chapter describes current findings from the research into postoperative cognitive dysfunction (POCD) following cardiac and non-cardiac surgery in older adults. The evidence suggests that a significant proportion of patients show POCD in the early weeks following surgery and anesthesia. Specific domains of cogniti...

journal_title：Progress in brain research

authors： Caza N,Taha R,Qi Y,Blaise G

更新日期：2008-01-01 00:00:00

abstract：:Characteristic features of autism include atypical social perception and social-communication skills, and atypical visual attention, alongside rigid and repetitive thinking and behavior. Debate has focused on whether the later emergence of atypical social skills is a consequence of attention problems early in life, or...

journal_title：Progress in brain research

authors： Elsabbagh M,Holmboe K,Gliga T,Mercure E,Hudry K,Charman T,Baron-Cohen S,Bolton P,Johnson MH,BASIS Team.

更新日期：2011-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00