Neuronal responses to injury and aging: lessons from animal models.

abstract：:Hand preference is a sensorimotor skill whose development both reflects and promotes the development of hemispheric lateralization for manual and cognitive functions. Extensive comparative, crosscultural, and paleoanthropological evidence demonstrates the prevalence of limb lateralized preferences across vertebrate sp...

journal_title：Progress in brain research

authors： Michel GF,Babik I,Nelson EL,Campbell JM,Marcinowski EC

更新日期：2018-01-01 00:00:00

abstract：:Recent accounts of tinnitus development and maintenance assign an important role to central mechanisms. Residual inhibition is a frequent phenomenon in individuals with tinnitus, and refers to the fact that tinnitus can temporarily be reduced by presenting sounds or noises that inhibit tinnitus for a limited time even...

journal_title：Progress in brain research

authors： Struve M,Diesch E,Flor H

更新日期：2007-01-01 00:00:00

abstract：:The cognitive changes that occur with ageing are usually referred to as 'age-related cognitive decline'. The most pronounced changes may be found in the executive functions that require integrity of the prefrontal cortical circuitry. With age, sleep also changes profoundly, with more sleep fragmentation, earlier awake...

journal_title：Progress in brain research

authors： Altena E,Ramautar JR,Van Der Werf YD,Van Someren EJ

更新日期：2010-01-01 00:00:00

abstract：:Schwann cells (SCs), when implanted in the injured spinal cord, support regeneration of axons, myelinate or ensheathe regenerated axons in a normal way, reduce cyst formation in the injured tissue, reduce secondary damage of tissue around the initial injury site, and modestly improve limb movements. If SC transplantat...

journal_title：Progress in brain research

authors： Wiliams RR,Bunge MB

更新日期：2012-01-01 00:00:00

abstract：:Studies with nicotine have, from the outset, been of fundamental importance for the elucidation of physiological mechanisms. However, many nicotinic cholinoreceptors do not appear to subserve a physiological role, at least within the present framework of knowledge. The main challenge in the immediate future is to dete...

journal_title：Progress in brain research

authors： Rand MJ

更新日期：1989-01-01 00:00:00

abstract：:Neural transplantation has emerged as a possible therapy for Parkinson's disease (PD). Clinical studies performed during the 1990s, where dopaminergic neurons derived from the human embryonic brain were transplanted into striatum of patients with PD, provided proof-of-principle that long-lasting therapeutic benefits c...

journal_title：Progress in brain research

authors： Brundin P,Barker RA,Parmar M

更新日期：2010-01-01 00:00:00

abstract：:The cellular and ionic mechanisms that generate the rhythm in central pattern generator (CPG) networks for simple movements are not well understood. Using vertebrate locomotion, respiration and mastication as exemplars, I describe four main principles of rhythmogenesis: (1) rhythmogenic ionic currents underlie all CPG...

journal_title：Progress in brain research

authors： Harris-Warrick RM

更新日期：2010-01-01 00:00:00

abstract：:Cerebral malformations are best understood as abnormal tissue morphogenesis in the context of disorders of ontogenesis. In neuroembryology, the timing of onset and duration of abnormal genetic expression and neurodevelopmental processes are primordial and must always be assessed, regardless whether the dysgenesis is p...

journal_title：Progress in brain research

authors： Sarnat HB,Flores-Sarnat L

更新日期：2014-01-01 00:00:00

abstract：:Glial scar encapsulation is thought to be one of the major reasons for the failure of chronic brain-machine interfaces. Many strategies, including modification of the probe surface chemistry, delivery of anti-inflammatory drugs, and changes of probe geometry, have been employed to reduce glial scar formation. We have ...

journal_title：Progress in brain research

authors： Ouyang L,Green R,Feldman KE,Martin DC

更新日期：2011-01-01 00:00:00

abstract：:Poor control of attention-related and motor processes, often associated with behavioural or cognitive impulsivity, are typical features of children and adults with attention-deficit hyperactivity disorder (ADHD). Until recently clinicians have observed little need to improve on or add to the catecholaminergic model fo...

journal_title：Progress in brain research

authors： Oades RD

更新日期：2008-01-01 00:00:00

abstract：:While a basic locomotor rhythm is centrally generated by spinal circuits, descending pathways are critical for ensuring appropriate anticipatory modifications of gait to accommodate uneven terrain. Neurons in the motor cortex command the changes in muscle activity required to modify limb trajectory when stepping over ...

journal_title：Progress in brain research

authors： Drew T,Prentice S,Schepens B

更新日期：2004-01-01 00:00:00

abstract：:Recent upsurge in research has uncovered distinct circuitries that regulate appetite, energy expenditure and fat accrual under the supervision of hormonal feedback signalling of adipocyte leptin and gastric ghrelin in the hypothalamic integration of energy homeostasis. A host of messenger molecules of diverse chemical...

journal_title：Progress in brain research

authors： Kalra SP,Kalra PS

更新日期：2010-01-01 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors have been implicated as a mediator of neuronal injury associated with many neurological disorders including ischemia, epilepsy, brain trauma, dementia and neurodegenerative disorders such as Parkinson's disease (PD) and Alzheimer's disease. To this, non-selective NMDA receptor ant...

journal_title：Progress in brain research

authors： Gardoni F,Ghiglieri V,Di Luca M,Calabresi P

更新日期：2010-01-01 00:00:00

abstract：:Much of the past research on how reward motivation and emotional information influence brain and behavior has been conducted separately. Recently, a few behavioral and brain imaging studies have investigated how reward and emotional information co-jointly impact brain and behavior. The present chapter reviews findings...

journal_title：Progress in brain research

authors： Padmala S,Sambuco N,Pessoa L

更新日期：2019-01-01 00:00:00

abstract：:Mechanism is at the heart of understanding, and this chapter addresses underlying brain mechanisms and pathways of cognition and the impact of sleep on these processes, especially those serving learning and memory. This chapter reviews the current understanding of the relationship between sleep/waking states and cogni...

journal_title：Progress in brain research

authors： Poe GR,Walsh CM,Bjorness TE

更新日期：2010-01-01 00:00:00

abstract：:It was generally accepted by the early 1960s that proton beam radiosurgery was too complex and impractical. The need was seen for a new machine. The beam design had to be as good as a proton beam. It was also decided that a static design was preferable even if the evolution of that notion is no longer clear. Complex c...

journal_title：Progress in brain research

authors： Ganz JC

更新日期：2014-01-01 00:00:00

abstract：:The study of chimeric retinas has yielded insight on the early development of retina. The close match in chimerism ratios between right and left retinas is significant and supports the idea that both retinas originate from a common population of progenitors. We are able to estimate numbers of progenitor cells that con...

journal_title：Progress in brain research

authors： Goldowitz D,Rice DS,Williams RW

更新日期：1996-01-01 00:00:00

abstract：:Oxidative stress is known to play a key role in the initiation and promotion of the neurodegeneration that characterizes the pathogenesis of Alzheimer disease (AD). An accumulation of redox active transition metals, including iron and copper, is likely a major generator of reactive oxidative species and other free rad...

journal_title：Progress in brain research

authors： Liu G,Men P,Perry G,Smith MA

更新日期：2009-01-01 00:00:00

abstract：:When an object partially or completely disappears behind an occluding surface, a representation of that object persists. For example, fragments of no longer visible objects can serve as an input into mid-level constructive visual processes, interacting and integrating with currently visible portions to form perceptual...

journal_title：Progress in brain research

authors： McCarthy JD,Erlikhman G,Caplovitz GP

更新日期：2017-01-01 00:00:00

abstract：:The development of atherosclerotic cardiovascular disease is a common comorbidity in patients with the metabolic syndrome, a concurrence of cardiovascular risk factors in one individual. While multiple growth factors and adipokines are identified in atherosclerotic lesions, as well as neurotrophins implicated in both ...

journal_title：Progress in brain research

authors： Chaldakov GN,Fiore M,Stankulov IS,Manni L,Hristova MG,Antonelli A,Ghenev PI,Aloe L

更新日期：2004-01-01 00:00:00

abstract：:Oestrogens (E) influence the activity of oxytocin (OT) producing neurons and heighten the rate of transcription of the oxytocin receptor (OTR) gene. Working through synergistic activities of two different oestrogen receptors (ERs), likely gene duplication products, in the hypothalamus and amygdala, E supports social r...

journal_title：Progress in brain research

authors： Choleris E,Devidze N,Kavaliers M,Pfaff DW

更新日期：2008-01-01 00:00:00

abstract：:Injuries to the adult mammalian spinal cord often lead to severe damage to both ascending (sensory) pathways and descending (motor) nerve pathways without the perspective of complete functional recovery. Future spinal cord repair strategies should comprise a multi-factorial approach addressing several issues, includin...

journal_title：Progress in brain research

authors： Hendriks WT,Ruitenberg MJ,Blits B,Boer GJ,Verhaagen J

更新日期：2004-01-01 00:00:00

abstract：:Motor control of different segments of the body with multiple degrees of freedom appears to be coordinated by utilizing preferred axes of motor activity. This hypothesis may also be applied to vestibular control of posture. To explore this question we studied the anatomical relationship between the head and the cervic...

journal_title：Progress in brain research

authors： Vidal PP,Wang DH,Graf W,de Waele C

更新日期：1993-01-01 00:00:00

abstract：:This investigation was designed to study the role of muscarinic receptor subtypes in the cardiovascular responses elicited by microinjection of cholinergic agonists in the intermediate portion of the NTS, the VLPA and VLDA areas and the IML of the spinal cord. Microinjections of L-glutamate (1.77 nmol in 20-50 nl in 0...

journal_title：Progress in brain research

authors： Sapru HN

更新日期：1989-01-01 00:00:00

abstract：:This contribution reviewed the available evidence on the domain-specific and domain-general neurocognitive determinants of children's arithmetic development, other than nonsymbolic numerical magnitude processing, which might have been overemphasized as a core factor of individual differences in mathematics and dyscalc...

journal_title：Progress in brain research

authors： Vanbinst K,De Smedt B

更新日期：2016-01-01 00:00:00

abstract：:The impact of spinal cord injury on an individual's gastrointestinal tract function is often poorly understood by the general public and also by those involved with persons with spinal cord injury. This chapter reviews the anatomy, physiology and function of the gastrointestinal tract, with particular emphasis on neur...

journal_title：Progress in brain research

authors： Chung EA,Emmanuel AV

更新日期：2006-01-01 00:00:00

abstract：:The success of axon regeneration in the adult mammalian brain depends on the presence of growth-permissive environmental conditions as well as on specific properties of the affected neurons. To investigate the relative contribution of extrinsic cues and intrinsic determinants to reparative processes we have investigat...

journal_title：Progress in brain research

authors： Rossi F,Bravin M,Buffo A,Fronte M,Savio T,Strata P

更新日期：1997-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:This is a brief review of event-related brain potentials (ERPs) as indices of cortical information processing in conditions in which conscious perception of stimuli is supposed to be absent: sleep, coma, vegetative state, general anesthesia, neglect as well as presentation of subliminal or masked stimuli. Exogenous ER...

journal_title：Progress in brain research

authors： Kotchoubey B

更新日期：2005-01-01 00:00:00

abstract：:The epileptologically informed in-depth analysis of auto- and heteroanamnestic historical sources supports the hypothesis that Hector Berlioz (1803-1869) might have suffered from a photosensitive idiopathic generalized epilepsy syndrome with absences, absence status, myoclonic seizures, and bilateral tonic-clonic seiz...

journal_title：Progress in brain research

authors： Altenmüller DM

更新日期：2015-01-01 00:00:00