Abstract：
:Studies with nicotine have, from the outset, been of fundamental importance for the elucidation of physiological mechanisms. However, many nicotinic cholinoreceptors do not appear to subserve a physiological role, at least within the present framework of knowledge. The main challenge in the immediate future is to determine the functional role of nicotinic cholinoceptors in the CNS. This knowledge will not only add to the physiological mechanisms that have been unravelled as a result of studies with nicotine, but will also provide a major contribution to the understanding of tobacco use.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Rand MJdoi
10.1016/s0079-6123(08)62461-9subject
Has Abstractpub_date
1989-01-01 00:00:00pages
3-11eissn
0079-6123issn
1875-7855pii
S0079-6123(08)62461-9journal_volume
79pub_type
杂志文章,评审abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)61005-4
更新日期：2007-01-01 00:00:00
abstract：:Research points to the notion that athletes have the potential to benefit from difficulty. This phenomenon-otherwise known as growth following adversity-has attracted increasing attention from sport psychology scholars. In this paper, we systematically review and synthesize the findings of studies in this area to bett...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2017.06.002
更新日期：2017-01-01 00:00:00
abstract：:Compensatory electromyographic (EMG) responses and several biomechanical parameters were studied following impulsive disturbance of the limbs during stance of human volunteers on a treadmill. Treadmill acceleration impulses were backwards or forwards directed, or their initial direction was reversed after 30 ms. Backw...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62238-4
更新日期：1989-01-01 00:00:00
abstract：:Resting state functional connectivity (rsFC) evaluated by detecting temporal co-variation of BOLD signals across multiple brain regions undergoes three major changes following sleep deprivation that indicate the occurrence of sleep intrusions; a loss of integration within networks like the default mode network as well...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2019.02.009
更新日期：2019-01-01 00:00:00
abstract：:This investigation was designed to study the role of muscarinic receptor subtypes in the cardiovascular responses elicited by microinjection of cholinergic agonists in the intermediate portion of the NTS, the VLPA and VLDA areas and the IML of the spinal cord. Microinjections of L-glutamate (1.77 nmol in 20-50 nl in 0...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62007-5
更新日期：1989-01-01 00:00:00
abstract：:Object recognition and visual attention are tightly linked processes in human perception. Over the last three decades, many models have been suggested to explain these two processes and their interactions, and in some cases these models appear to contradict each other. We suggest a unifying framework for object recogn...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)65005-X
更新日期：2007-01-01 00:00:00
abstract：:In this chapter, the distribution of Hsp70 in brain cell types following whole body hyperthermia is reviewed. The prevalence of Hsp70 expression in oligodendrocytes, microglia, and vascular cells in this type of stress contrasts with scarcity of Hsp70 induction in astrocytes and most neurons of the hyperthermic brain....
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)62020-7
更新日期：2007-01-01 00:00:00
abstract：:A dense serotonin (5-HT)-containing projection to the superficial layers of the superior colliculus (SC) has been demonstrated in diverse mammalian species, but how 5-HT may affect visual signals within these laminae is largely unknown. This study undertook to investigate the distribution of 2 types of 5-HT receptors ...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)63320-8
更新日期：1996-01-01 00:00:00
abstract：:Today's researchers are faced with a change from curiosity-driven to mandate-driven research. These two approaches are well combined within scientific networks (Actions) supported by the European Cooperation in Science and Technology (COST) program. The functioning of COST Actions, although directed only to networking...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-63486-3.09999-0
更新日期：2014-01-01 00:00:00
abstract：:Spinal cord evoked potentials (SCEP) are good indicators of spinal cord function in health and disease. Disturbances in SCEP amplitudes and latencies during spinal cord monitoring predict spinal cord pathology following trauma. Treatment with neuroprotective agents preserves SCEP and reduces cord pathology after injur...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2020.09.012
更新日期：2020-01-01 00:00:00
abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(02)37008-0
更新日期：2002-01-01 00:00:00
abstract：:Recent years have brought a rapid growth in knowledge of the prodromal phase of Parkinson's disease (PD). It is now clear that the clinical phase of PD is preceded by a phase of progressing neurodegeneration lasting many years. This involves not only central nervous system structures outside the substantia nigra and n...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2020.01.003
更新日期：2020-01-01 00:00:00
abstract：:Much of the past research on how reward motivation and emotional information influence brain and behavior has been conducted separately. Recently, a few behavioral and brain imaging studies have investigated how reward and emotional information co-jointly impact brain and behavior. The present chapter reviews findings...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2019.03.023
更新日期：2019-01-01 00:00:00
abstract：:The serotonin (5-HT) neurotransmitter system provides fundamental modulatory regulation of the limbic-corticostriatal circuitry known to be vital in the development of addiction as well as the aspects of addiction that hinder recovery and contribute to relapse. Thus, components of the 5-HT system may provide novel tar...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(08)00916-3
更新日期：2008-01-01 00:00:00
abstract：:Otoacoustic emissions can be used to study cochlear function in an objective, non-invasive and rapid manner. These and other desirable features of emissions have inspired a significant amount of investigation into the practicalities of utilizing evoked emissions as clinical tests of hearing. Variables which affect the...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62265-7
更新日期：1993-01-01 00:00:00
abstract：:Intracellular recordings from 103 photoreceptors in the excised pineal body of adult trouts were obtained by using single electrode current- and voltage-clamp techniques. The photoresponses to brief flashes showed the same polarity but a slower time course than those previously recorded from retinal photoreceptors of ...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)60352-0
更新日期：1993-01-01 00:00:00
abstract：:In vivo functional imaging has provided objective evidence for the integration and function of nigral grafts in the brains of patients with Parkinson's disease. Clinical trials with the use of positron emission tomography have shown that transplants of human dopamine-rich fetal ventral mesencephalic tissue can survive...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-59575-1.00009-0
更新日期：2012-01-01 00:00:00
abstract：:Orexin, also known as hypocretin, is a hypothalamic neuropeptide important for mediation of arousal and sleep as well as feeding and energy homeostasis. Recent studies have indicated that orexin also plays a key role regulating motivation and reward associated with food intake and with drugs of abuse. Based on those f...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-59489-1.00006-9
更新日期：2012-01-01 00:00:00
abstract：:Large-scale neural simulations have the marks of a distinct methodology which can be fruitfully deployed in neuroscience. I distinguish between two types of applications of the simulation methodology in neuroscientific research. Model-oriented applications aim to use the simulation outputs to derive new hypotheses abo...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2017.05.004
更新日期：2017-01-01 00:00:00
abstract：:When we move our eyes around in real-world scenes, we typically have several peripheral previews of an object before we direct our eyes straight at the object. Numerous studies on transsaccadic memory have investigated whether there is any evidence for the integration of peripheral object information acquired presacca...
journal_title：Progress in brain research
pub_type： 临床试验,杂志文章
doi：10.1016/s0079-6123(02)40050-7
更新日期：2002-01-01 00:00:00
abstract：:The idea of the dentate gyrus as a gate or filter at the entrance to the hippocampus, blocking or filtering incoming excitation from the entorhinal cortex, has been an intriguing one. Here we review the historical development of the idea, and discuss whether it may be possible to be more specific in defining this gate...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(07)63032-5
更新日期：2007-01-01 00:00:00
abstract：:Variation in neocortex size is one of the defining features of mammalian brain evolution. The paramount assumption has been that neocortex size indicates a monotonic allometric relationship with brain size. This assumption holds the concomitant neurodevelopmental assumption that the ontogenetic trajectory of neocortex...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2019.05.002
更新日期：2019-01-01 00:00:00
abstract：:When discrepant stimuli are presented to each eye and fusion is impossible, perception spontaneously oscillates between the two patterns (binocular rivalry). Functional MRI (fMRI) research identified a frontoparietal network in the right hemisphere associated with perceptual transitions, and it has been proposed that ...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/S0079-6123(06)55013-7
更新日期：2006-01-01 00:00:00
abstract：:Primates are endowed with a brain about twice the size that of a mammal with the same body size, and humans have the largest brain relative to body size of all animals. This increase in brain size may be related to the acquisition of higher cognitive skills that permitted more complex social interactions, the evolutio...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53860-4.00001-5
更新日期：2012-01-01 00:00:00
abstract：:For diagnostic purposes, a differentiation can be made between the locus coeruleus (LC) in normal brain and the LC, in senile dementia of the Alzheimer's type (SDAT) and Parkinson's disease (PD). The differentiation is based on findings concerning the morphological alterations of the TH-immunoreactive; neurons, on the...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)63839-x
更新日期：1991-01-01 00:00:00
abstract：:A remarkable preparation for studying development and repair is the CNS of the newborn opossum which, removed in its entirety, survives in culture for more than 1 week. In suitable medium, cells continue to divide, mature and reflex activity is maintained. Moreover, nerve fibers grow rapidly, reliably and extensively ...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)61141-3
更新日期：1994-01-01 00:00:00
abstract：:Acute intermittent hypoxia (AIH) triggers a form of respiratory plasticity known as long-term facilitation (LTF), which is manifested as a progressive increase in respiratory motor activity that lasts for minutes to hours after the hypoxic stimulus is removed. Respiratory LTF has been reported in numerous animal model...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/B978-0-444-63488-7.00011-2
更新日期：2014-01-01 00:00:00
abstract：:Fatigue is considered to be an important and frequent factor in motivation problems. However, this term lacks clinical and pathophysiological validity. Semantic precision has to be improved. Lack of drive and tiredness with increased sleepiness as observed in fatigue in the context of inflammatory and immunological pr...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2016.06.001
更新日期：2016-01-01 00:00:00
abstract：:Acute spinal cord injury (SCI) is a devastating neurological disorder that can affect any individual at a given instance. Current treatment options for SCI include the use of high dose methylprednisolone sodium succinate, a corticosteroid, surgical interventions to stabilize and decompress the spinal cord, intensive m...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)61015-7
更新日期：2007-01-01 00:00:00
abstract：:Why do complex-partial seizures in temporal lobe epilepsy (TLE) cause a loss of consciousness? Abnormal function of the medial temporal lobe is expected to cause memory loss, but it is unclear why profoundly impaired consciousness is so common in temporal lobe seizures. Recent exciting advances in behavioral, electrop...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(09)17711-7
更新日期：2009-01-01 00:00:00
