Learning from large-scale neural simulations.

abstract：:The receptor tyrosine kinase B, TrkB, is the high-affinity receptor for brain-derived neurotrophic factor (BDNF). Much evidence supports a role for TrkB signaling in excitatory synapse formation. There have been a number of recent advances in understanding the cell biology of TrkB-mediated excitatory synaptogenesis. T...

journal_title：Progress in brain research

authors： Luikart BW,Parada LF

更新日期：2006-01-01 00:00:00

abstract：:The visual system is tied to the retina. Because the eyes move in the orbit, and the head moves on the body, accurate location of an object in extrapersonal space cannot simply result from a visual signal. Instead, the retinal signal must be combined with an estimate of where the eyes are in the orbit, and where the h...

journal_title：Progress in brain research

authors： Zhang M,Wang X,Goldberg ME

更新日期：2008-01-01 00:00:00

abstract：:PTSD arises by definition as a direct consequence of the experience of an acute severe stressor. The formation of traumatic memory and its extinction, sympathetic and adrenocortical stress systems activity in relation to individual vulnerability form the core of animal models for PTSD. ...

journal_title：Progress in brain research

authors： Oitzl MS

更新日期：2008-01-01 00:00:00

abstract：:In addition to its peripheral secretion from the neurohypophysis, the neuropeptide vasopressin (VP) is released within the mammalian brain from probably all parts of the neuronal membrane. In particular the development of brain microdialysis in vivo together with blood microdialysis or blood sampling provides the adva...

journal_title：Progress in brain research

authors： Landgraf R,Wotjak CT,Neumann ID,Engelmann M

更新日期：1998-01-01 00:00:00

abstract：:The hypothalamic-neurohypophysial system undergoes dramatic morphological plasticity in response to physiological activation during parturition/lactation and dehydration, including somatic swelling, decreased glial coverage and increased synaptic innervation of the magnocellular neuroendocrine cells. Recent in-vitro e...

journal_title：Progress in brain research

authors： Tasker JG,Di S,Boudaba C

更新日期：2002-01-01 00:00:00

abstract：:What are the building blocks of our visual representations? Whatever we look at, the things we see will have some feature variability: even snow is not purely white but has a range of shades of white. However, in most studies investigating visual perception, homogeneous displays with all stimuli having a very limited ...

journal_title：Progress in brain research

authors： Chetverikov A,Campana G,Kristjánsson Á

更新日期：2017-01-01 00:00:00

abstract：:Evidence for a non-monosynaptic Ia excitation of wrist flexor and quadriceps motoneurones (MNs) in man has been provided while using two independent methods: construction of post-stimulus time histograms (PSTHs) of voluntarily activated motor units and the spatial facilitation of the H-reflex. This non-monosynaptic Ia...

journal_title：Progress in brain research

authors： Pierrot-Deseilligny E

更新日期：1989-01-01 00:00:00

abstract：:Recordings of spinal INs during a flexion/extension wrist task with an instructed delay period have shown directly that many spinal neurons modulate their rate during the preparatory period soon after a visual cue. The onset time and the relation between the delay period activity of spinal INs and the ensuing movement...

journal_title：Progress in brain research

authors： Prut Y,Perlmutter SI,Fetz EE

更新日期：2001-01-01 00:00:00

abstract：:The development of atherosclerotic cardiovascular disease is a common comorbidity in patients with the metabolic syndrome, a concurrence of cardiovascular risk factors in one individual. While multiple growth factors and adipokines are identified in atherosclerotic lesions, as well as neurotrophins implicated in both ...

journal_title：Progress in brain research

authors： Chaldakov GN,Fiore M,Stankulov IS,Manni L,Hristova MG,Antonelli A,Ghenev PI,Aloe L

更新日期：2004-01-01 00:00:00

abstract：:Paired organotypic explants from rat occipital cortex were cultured for up to three weeks in the presence of selective blockers of amino acid receptor blockers, during which period spontaneous action potential generation was monitored electrophysiologically. In contrast to isolated explants (Corner, M.A., van Pelt, J....

journal_title：Progress in brain research

authors： Corner MA,Baker RE,van Pelt J,Wolters PS

更新日期：2005-01-01 00:00:00

abstract：:A remarkable preparation for studying development and repair is the CNS of the newborn opossum which, removed in its entirety, survives in culture for more than 1 week. In suitable medium, cells continue to divide, mature and reflex activity is maintained. Moreover, nerve fibers grow rapidly, reliably and extensively ...

journal_title：Progress in brain research

authors： Nicholls JG,Vischer H,Varga Z,Erulkar S,Saunders NR

更新日期：1994-01-01 00:00:00

abstract：:John Bell, brother-surgeon of Charles Bell, was, like Charles, an outstanding surgeon and a good artist. John was one of the few who illustrated his work with their own drawings in the days before audiovisual aids were available and without the benefit of reliable drawing aids, photography and computer-aided design. C...

journal_title：Progress in brain research

authors： Gardner-Thorpe C

更新日期：2013-01-01 00:00:00

abstract：:Neurons in the midbrain superior colliculus (SC) have the ability to integrate information from different senses to profoundly increase their sensitivity to external events. This not only enhances an organism's ability to detect and localize these events, but to program appropriate motor responses to them. The surviva...

journal_title：Progress in brain research

authors： Stein BE,Rowland BA

更新日期：2011-01-01 00:00:00

abstract：:When discrepant stimuli are presented to each eye and fusion is impossible, perception spontaneously oscillates between the two patterns (binocular rivalry). Functional MRI (fMRI) research identified a frontoparietal network in the right hemisphere associated with perceptual transitions, and it has been proposed that ...

journal_title：Progress in brain research

authors： Valle-Inclán F,Gallego E

更新日期：2006-01-01 00:00:00

abstract：:Based on a review of anatomical and physiological findings, we suggest that the hippocampus may be viewed as a positive feedback device (autoassociator), which is capable of modifying the activity of the neocortical neurons. We examine the three-dimensional organization of evoked and spontaneous physiological patterns...

journal_title：Progress in brain research

authors： Buzsáki G,Chen LS,Gage FH

更新日期：1990-01-01 00:00:00

abstract：:The noradrenergic (NA) afferent projection to the cerebellar cortex, which originates mainly from the locus coeruleus (LC), may act on the target neurons by utilizing both alpha- and beta-adrenoceptors. Experiments performed in decerebrate cats have shown that unilateral injection into the vermal cortex of the cerebel...

journal_title：Progress in brain research

authors： Andre P,d'Ascanio P,Pompeiano O

更新日期：1991-01-01 00:00:00

abstract：:Spinal cord injury (SCI) typically damages the long axonal tracts of the spinal cord which results in permanent disability. However, regeneration of the injured spinal cord is approaching reality according to the advances in stem cell biology. Cell transplantation therapy holds potential to lead to recovery following ...

journal_title：Progress in brain research

authors： Nori S,Nakamura M,Okano H

更新日期：2017-01-01 00:00:00

abstract：:The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy. The overall objective o...

journal_title：Progress in brain research

authors： Koivuniemi A,Wilks SJ,Woolley AJ,Otto KJ

更新日期：2011-01-01 00:00:00

abstract：:The idea of the dentate gyrus as a gate or filter at the entrance to the hippocampus, blocking or filtering incoming excitation from the entorhinal cortex, has been an intriguing one. Here we review the historical development of the idea, and discuss whether it may be possible to be more specific in defining this gate...

journal_title：Progress in brain research

authors： Hsu D

更新日期：2007-01-01 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) are widely distributed in the central nervous system and have been implicated in multiple behavioral paradigms and pathological conditions. Nicotinic therapeutic interventions require an extensive characterization of native nAChRs including mapping of their distribution and f...

journal_title：Progress in brain research

authors： Alkondon M,Albuquerque EX

更新日期：2004-01-01 00:00:00

abstract：:This overview highlights the presentations made by several authors, with sidelights commentaries on the topics covered in this session. The Neurotropic hypothesis, formulated by Cajal more than one century ago, has been one of the fundamental tenets of modern Neuroscience. Research work is unveiling highly complex mol...

journal_title：Progress in brain research

authors： Valverde F

更新日期：2002-01-01 00:00:00

abstract：:In mammals, the circadian system is composed of the central clock in the hypothalamic suprachiasmatic nuclei and of peripheral clocks that are located in other neural structures and in cells of the peripheral tissues and organs. In adults, the system is hierarchically organized so that the central clock provides the o...

journal_title：Progress in brain research

authors： Sumova A,Sladek M,Polidarova L,Novakova M,Houdek P

更新日期：2012-01-01 00:00:00

abstract：:Three rhythmic movements, breathing, walking, and chewing, are considered from the perspective of the emerging factors that control their coordination. This takes us beyond the concept of a core excitatory kernel and into the common principles that govern the interaction between components of the neural networks that ...

journal_title：Progress in brain research

authors： Jordan LM,Sławińska U

更新日期：2011-01-01 00:00:00

abstract：:In order to study cerebral activity related to preparation and execution of movement, evoked and induced brain electrical activities were compared to each other and to fMRI results in voluntary self-paced movements. Also, the event-related desynchronization and synchronization (ERD/ERS) were studied in complex movemen...

journal_title：Progress in brain research

authors： Rektor I,Sochůrková D,Bocková M

更新日期：2006-01-01 00:00:00

abstract：:Quantitative models of the oculomotor plant and control of the saccadic eye movement system are presented in this chapter. Oculomotor plant models described here are linear, including a second-order model by Westheimer (1954), Bahill et al. (1980) and Enderle et al. (2000). The model of the saccade generator is initia...

journal_title：Progress in brain research

authors： Enderle JD

更新日期：2002-01-01 00:00:00

abstract：:Several studies provided evidence for neuroendocrine dysregulations in adults with a history of child sexual abuse. This review focuses on neuroendocrine studies in sexually abused children and adolescents, dating from January 1, 1990 to January 1, 2007 and obtained from a systematic Medline Indexed literature search ...

journal_title：Progress in brain research

authors： Bicanic IA,Meijer M,Sinnema G,van de Putte EM,Olff M

更新日期：2008-01-01 00:00:00

abstract：:We developed a theoretical framework for studying coordination strategies in standing posture. The framework consists of a musculoskeletal model of the human lower extremity in the sagittal plane and a technique to visualize, geometrically, how constraints internal and external to the body affect movement. The set of ...

journal_title：Progress in brain research

authors： Kuo AD,Zajac FE

更新日期：1993-01-01 00:00:00

abstract：:Rebound nystagmus, a common cerebellar sign, is a transient nystagmus that appears on returning to straight-ahead gaze after prolonged eccentric gaze. The slow phases of rebound nystagmus are in the direction of prior eccentric gaze. After eccentric gaze, healthy subjects also show rebound nystagmus when fixation is r...

journal_title：Progress in brain research

authors： Otero-Millan J,Colpak AI,Kheradmand A,Zee DS

更新日期：2019-01-01 00:00:00

abstract：:Social cognitive skills play a crucial role in human life, and have allowed us to reach a unique level of behavioral and cultural complexity. However, many nonhuman species also show a complex understanding of the social world. Building on theories of human social development, we will follow the emergence of cultural ...

journal_title：Progress in brain research

authors： Cacchione T,Amici F

更新日期：2020-01-01 00:00:00

abstract：:This chapter provides evidence of spatial and temporal changes in the behavior of neurons within Areas 5 and 4 of the sensorimotor cortex of a nonhuman primate while it was executing a perturbed arm-reaching task. Chronically implanted electrode arrays were used to record simultaneously from 37 to 58 neurons. Also mea...

journal_title：Progress in brain research

authors： Weber DJ,He J

更新日期：2004-01-01 00:00:00