Abstract:
:For diagnostic purposes, a differentiation can be made between the locus coeruleus (LC) in normal brain and the LC, in senile dementia of the Alzheimer's type (SDAT) and Parkinson's disease (PD). The differentiation is based on findings concerning the morphological alterations of the TH-immunoreactive; neurons, on the topographical distribution of neuron loss within the length of the LC, and on the total reduction in cell number.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Chan-Palay Vdoi
10.1016/s0079-6123(08)63839-xsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
625-30eissn
0079-6123issn
1875-7855pii
S0079-6123(08)63839-Xjournal_volume
88pub_type
杂志文章abstract::Ocular dominance plasticity may be the paradigmatic in vivo model of activity-dependent plasticity. More than four decades of intense research has delineated the network-level rules that govern synaptic change in this model. The recent characterization of a murine model for ocular dominance plasticity has facilitated ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(04)47008-3
更新日期:2005-01-01 00:00:00
abstract::Modern philosophy of mind cannot be understood without recent developments in computer science, artificial intelligence (AI), robotics, neuroscience, biology, linguistics, and psychology. Classical philosophy of formal languages as well as symbolic AI assume that all kinds of knowledge must explicitly be represented b...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(07)68010-8
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Primary angle-closure glaucoma (PACG) is the leading cause of blindness in East Asia. The disease can be classified into primary angle-closure suspect, primary angle closure (PAC), and PACG. Pupil-block, anterior nonpupil-block (plateau iris and peripheral iris crowding), lens related and retrolenticular m...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/S0079-6123(08)01104-7
更新日期:2008-01-01 00:00:00
abstract::Studies on the visual thalamic relays, the lateral geniculate nucleus and pulvinar, provide three key properties that have dramatically changed the view that the thalamus serves as a simple relay to get information from subcortical sites to cortex. First, the retinal input, although a small minority (7%) in terms of n...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(05)49009-3
更新日期:2005-01-01 00:00:00
abstract::The subiculum gives rise to the majority of hippocampal projections to various telencephalic and diencephalic structures. Previously, these projections have been described using anterograde tracing with radioactively labeled amino acids. As part of an ongoing detailed analysis of the connectivity of the hippocampal re...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/s0079-6123(08)61240-6
更新日期:1990-01-01 00:00:00
abstract::An essential component of the brain extracellular space is the extracellular matrix contributing to the spatial assembly of cells by binding cell-surface adhesion molecules, supporting cell migration, differentiation, and tissue development. The most interesting and complex functions of the central nervous system are ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/B978-0-444-63486-3.00010-4
更新日期:2014-01-01 00:00:00
abstract::What are the building blocks of our visual representations? Whatever we look at, the things we see will have some feature variability: even snow is not purely white but has a range of shades of white. However, in most studies investigating visual perception, homogeneous displays with all stimuli having a very limited ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/bs.pbr.2017.07.001
更新日期:2017-01-01 00:00:00
abstract::Noradrenergic LC neurons appear to be relatively unique in the brain, being unsurpassed in the divergence and ubiquity of their projections through the central nervous system. In this regard, they share certain characteristics with peripheral noradrenaline neurons of the sympathetic nervous system. As such they would ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)63797-8
更新日期:1991-01-01 00:00:00
abstract::Studies with nicotine have, from the outset, been of fundamental importance for the elucidation of physiological mechanisms. However, many nicotinic cholinoreceptors do not appear to subserve a physiological role, at least within the present framework of knowledge. The main challenge in the immediate future is to dete...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)62461-9
更新日期:1989-01-01 00:00:00
abstract::The epileptologically informed in-depth analysis of auto- and heteroanamnestic historical sources supports the hypothesis that Hector Berlioz (1803-1869) might have suffered from a photosensitive idiopathic generalized epilepsy syndrome with absences, absence status, myoclonic seizures, and bilateral tonic-clonic seiz...
journal_title:Progress in brain research
pub_type: 传,历史文章,杂志文章
doi:10.1016/bs.pbr.2014.11.007
更新日期:2015-01-01 00:00:00
abstract::Humans can communicate their emotional state via facial expression and affective prosody. This chapter reviews behavioural, neuroanatomical, electrophysiological and neuroimaging studies pertaining to audiovisual integration of emotional communicative signals. Particular emphasis will be given to neuroimaging studies ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)56019-4
更新日期:2006-01-01 00:00:00
abstract::Disrupted in Schizophrenia-1 (DISC1) is one of the most likely susceptibility genes for schizophrenia (SZ). DISC1 is being established as a hub protein with various functions in the pre- and postnatal development of the nervous system. Since generation of a knockout (KO) mouse has proved challenging, various alternati...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(09)17909-8
更新日期:2009-01-01 00:00:00
abstract::Recordings of spinal INs during a flexion/extension wrist task with an instructed delay period have shown directly that many spinal neurons modulate their rate during the preparatory period soon after a visual cue. The onset time and the relation between the delay period activity of spinal INs and the ensuing movement...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(01)30018-3
更新日期:2001-01-01 00:00:00
abstract::Large-scale neural simulations have the marks of a distinct methodology which can be fruitfully deployed in neuroscience. I distinguish between two types of applications of the simulation methodology in neuroscientific research. Model-oriented applications aim to use the simulation outputs to derive new hypotheses abo...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/bs.pbr.2017.05.004
更新日期:2017-01-01 00:00:00
abstract::There has been substantial progress in our understanding of the hippocampus in the past 70 years. During this time, it has become clear that the hippocampus is not an olfactory-related structure alone, but plays critical roles in other functions that do not necessarily depend on olfaction, such as learning and memory....
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(07)63002-7
更新日期:2007-01-01 00:00:00
abstract::In recent years the scientific community has come to appreciate that the early cortical representations for visually guided arm movements are probably coded in a visual frame, i.e. relative to retinal landmarks. While this scheme accounts for many behavioral and neurophysiological observations, it also poses certain p...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(02)40060-X
更新日期:2002-01-01 00:00:00
abstract::The major point of this chapter is that there is evidence to support the idea that cervical headache might not only result from injured somatic structures in the neck but also occur because of interactions with visceral organs. The complex arrangement of convergent inputs from somatic and visceral afferent fibers and ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)62140-8
更新日期:2000-01-01 00:00:00
abstract::The impact of spinal cord injury on an individual's gastrointestinal tract function is often poorly understood by the general public and also by those involved with persons with spinal cord injury. This chapter reviews the anatomy, physiology and function of the gastrointestinal tract, with particular emphasis on neur...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(05)52021-1
更新日期:2006-01-01 00:00:00
abstract::In the neostriatum, GABAergic inhibition arises from the action of at least two classes of inhibitory interneurons, and from recurrent collaterals of the principal cells. Interneurons receive excitatory input only from extrinsic sources, and so act in a purely feedforward capacity. Feedback inhibition arises from the ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)60006-X
更新日期:2007-01-01 00:00:00
abstract::Variation in neocortex size is one of the defining features of mammalian brain evolution. The paramount assumption has been that neocortex size indicates a monotonic allometric relationship with brain size. This assumption holds the concomitant neurodevelopmental assumption that the ontogenetic trajectory of neocortex...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/bs.pbr.2019.05.002
更新日期:2019-01-01 00:00:00
abstract::Evidence for a non-monosynaptic Ia excitation of wrist flexor and quadriceps motoneurones (MNs) in man has been provided while using two independent methods: construction of post-stimulus time histograms (PSTHs) of voluntarily activated motor units and the spatial facilitation of the H-reflex. This non-monosynaptic Ia...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)62225-6
更新日期:1989-01-01 00:00:00
abstract::Over the past decade, hypothalamic circuits have been described that impact energy homeostasis in rodents and humans. Our drug development efforts for the treatment of obesity and the metabolic syndrome have largely focused on selected genetic and/or pharmacologically validated pathways. The translation of these pathw...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)53005-5
更新日期:2006-01-01 00:00:00
abstract::Alzheimer's disease (AD) is the most prevalent form of neurodegeneration; however, therapies to prevent or treat AD are inadequate. Amyloid-beta (Abeta) protein accrues in cortical senile plaques, one of the key neuropathological hallmarks of AD, and is elevated in brains of early onset AD patients in a small number o...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(09)17506-4
更新日期:2009-01-01 00:00:00
abstract::The present study involves the effects on corticotropin (ACTH) release of neuro- and thymoleptic tricyclic antidepressant compounds (TrcACs: chlorpromazine, promethazine, haloperidol, imipramine, amitriptyline) and their interactions with lysine-8-vasopressin (LVP) and corticosterone (B). As an in vitro model, 14-day ...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/s0079-6123(08)62322-5
更新日期:1992-01-01 00:00:00
abstract::Human evolution was marked by an extraordinary increase in total brain size relative to body size. While it is certain that increased encephalization is an important factor contributing to the origin of our species-specific cognitive abilities, it is difficult to disentangle which aspects of human neural structure and...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/B978-0-444-53860-4.00011-8
更新日期:2012-01-01 00:00:00
abstract::Hand preference is a sensorimotor skill whose development both reflects and promotes the development of hemispheric lateralization for manual and cognitive functions. Extensive comparative, crosscultural, and paleoanthropological evidence demonstrates the prevalence of limb lateralized preferences across vertebrate sp...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/bs.pbr.2018.06.007
更新日期:2018-01-01 00:00:00
abstract::Partly due to the failure of anthropology to productively engage the fields of psychology and neuroscience, investigations in cultural neuroscience have occurred largely without the active involvement of anthropologists or anthropological theory. Dramatic advances in the tools and findings of social neuroscience have ...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(09)17803-2
更新日期:2009-01-01 00:00:00
abstract::Object recognition and visual attention are tightly linked processes in human perception. Over the last three decades, many models have been suggested to explain these two processes and their interactions, and in some cases these models appear to contradict each other. We suggest a unifying framework for object recogn...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/S0079-6123(06)65005-X
更新日期:2007-01-01 00:00:00
abstract::Intron-specific probes measure heteronuclear RNA (hnRNA) levels and thus approximate the transcription rates of genes, in part because of the rapid turnover of this intermediate form of RNA in the cell nucleus. Previously, we used oxytocin (Oxt)- and vasopressin (Avp)- intron-specific riboprobes to measure changes in ...
journal_title:Progress in brain research
pub_type: 杂志文章
doi:10.1016/S0079-6123(08)00404-4
更新日期:2008-01-01 00:00:00
abstract::The studies reviewed in this chapter present a convincing argument that prostaglandins have direct actions at the level of the spinal cord to enhance nociception. Furthermore, an increasing body of evidence supports the hypothesis that one important site of action of these eicosanoids is the terminals of sensory neuro...
journal_title:Progress in brain research
pub_type: 杂志文章,评审
doi:10.1016/s0079-6123(08)61801-4
更新日期:1995-01-01 00:00:00