Molecular substrates of plasticity in the developing visual cortex.

abstract：:Fatigue is considered to be an important and frequent factor in motivation problems. However, this term lacks clinical and pathophysiological validity. Semantic precision has to be improved. Lack of drive and tiredness with increased sleepiness as observed in fatigue in the context of inflammatory and immunological pr...

journal_title：Progress in brain research

authors： Hegerl U,Ulke C

更新日期：2016-01-01 00:00:00

abstract：:Over the past decade, hypothalamic circuits have been described that impact energy homeostasis in rodents and humans. Our drug development efforts for the treatment of obesity and the metabolic syndrome have largely focused on selected genetic and/or pharmacologically validated pathways. The translation of these pathw...

journal_title：Progress in brain research

authors： Van der Ploeg LH,Kanatani A,MacNeil D,Ming Fong T,Strack A,Nargund R,Guan XM

更新日期：2006-01-01 00:00:00

abstract：:Human and nonhuman primates predictively use smooth pursuit and saccades to track visual targets that move in a fronto-parallel plane. This behaviour is believed to be facilitated by short-term memory of the target motion and/or an efference copy of the subject's motor effort. Subjects in our experiments tracked dicho...

journal_title：Progress in brain research

authors： Fu P,Chang R,O'Beirne K,King WM

更新日期：2008-01-01 00:00:00

abstract：:Various growth factors are present in the hippocampal formation and appear responsible for the prominent plasticity of this brain area. Although hormone-like growth-promoting polypeptides are the best known, recent studies emphasize the importance in the growth response of molecules such as laminin proteoglycans, neur...

journal_title：Progress in brain research

authors： Nieto-Sampedro M,Bovolenta P

更新日期：1990-01-01 00:00:00

abstract：:Results reported here confirm and extend those of early retrograde transport studies of the brainstem in the rat and cat. This study demonstrates substantial and multiple afferent projections to the cat locus coeruleus arising from neurons containing acetylcholine, serotonin, norepinephrine, epinephrine, dopamine, his...

journal_title：Progress in brain research

authors： Sakai K

更新日期：1991-01-01 00:00:00

abstract：:Nerve growth factor (NGF) is required for the survival of developing sympathetic and sensory neurons. In the absence of NGF, these neurons undergo protein synthesis-dependent apoptosis. Ten years have gone by since the first reports of specific genes being upregulated during NGF deprivation-induced cell death. Over th...

journal_title：Progress in brain research

authors： Freeman RS,Burch RL,Crowder RJ,Lomb DJ,Schoell MC,Straub JA,Xie L

更新日期：2004-01-01 00:00:00

abstract：:The interactions of the dendritically released neuropeptides vasopressin and oxytocin with co-released neuroactive substances such as opioids and nitric oxide are reviewed. Endogenous opioids regulate magnocellular neurons at the level of the supraoptic nucleus and the relationship of dendritically released peptides a...

journal_title：Progress in brain research

authors： Ludwig M,Sabatier N,Dayanithi G,Russell JA,Leng G

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:Primary angle-closure glaucoma (PACG) is the leading cause of blindness in East Asia. The disease can be classified into primary angle-closure suspect, primary angle closure (PAC), and PACG. Pupil-block, anterior nonpupil-block (plateau iris and peripheral iris crowding), lens related and retrolenticular m...

journal_title：Progress in brain research

authors： Amerasinghe N,Aung T

更新日期：2008-01-01 00:00:00

abstract：:Epileptic seizures cause dynamic, reversible changes in brain function and are often associated with loss of consciousness. Of all seizure types, absence seizures lead to the most selective deficits in consciousness, with relatively little motor or other manifestations. Impaired consciousness in absence seizures is no...

journal_title：Progress in brain research

authors： Blumenfeld H

更新日期：2005-01-01 00:00:00

abstract：:Disrupted in Schizophrenia-1 (DISC1) is one of the most likely susceptibility genes for schizophrenia (SZ). DISC1 is being established as a hub protein with various functions in the pre- and postnatal development of the nervous system. Since generation of a knockout (KO) mouse has proved challenging, various alternati...

journal_title：Progress in brain research

authors： Jaaro-Peled H

更新日期：2009-01-01 00:00:00

abstract：:Polyamine oxidase (PAO) is a FAD-dependent enzyme with a molecular mass of about 62 kDa, present with high activity in most tissues of vertebrates. Structural requirements of a substrate for PAO are two positively charged amino groups, separated by a short carbon chain and an alkyl substituent on one or both nitrogen ...

journal_title：Progress in brain research

authors： Seiler N

更新日期：1995-01-01 00:00:00

abstract：:Objects have specific cognitive attributes, elicit particular visuo-motor responses, and require visual processes beyond primary visual cortex to combine information over extended regions as a basis for the segmentation and integration of visual objects. As well as segmentation, the assignment of region boundaries to ...

journal_title：Progress in brain research

authors： Braddick O,Atkinson J

更新日期：2007-01-01 00:00:00

abstract：:Saccadic oscillations are unwanted back-to-back saccades occurring one upon the other that produce a high-frequency oscillation of the eyes (usually 15-30 Hz). These may occur transiently in normal subjects, for example, around the orthogonal axis of a purely horizontal or vertical saccade, during combined saccade-ver...

journal_title：Progress in brain research

authors： Ramat S,Leigh RJ,Zee DS,Shaikh AG,Optican LM

更新日期：2008-01-01 00:00:00

abstract：:A dense serotonin (5-HT)-containing projection to the superficial layers of the superior colliculus (SC) has been demonstrated in diverse mammalian species, but how 5-HT may affect visual signals within these laminae is largely unknown. This study undertook to investigate the distribution of 2 types of 5-HT receptors ...

journal_title：Progress in brain research

authors： Mooney RD,Huang X,Shi MY,Bennett-Clarke CA,Rhoades RW

更新日期：1996-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:Swallowing is an essential function in our daily life; nevertheless, stroke or other neurodegenerative diseases can cause the malfunction of swallowing function, ie, dysphagia. The objectives of this review are to understand the neural and cortical basis of swallowing and tongue, and review the latest techniques on th...

journal_title：Progress in brain research

authors： Yang H,Ang KK,Wang C,Phua KS,Guan C

更新日期：2016-01-01 00:00:00

abstract：:This chapter has highlighted how correlates of neuronal plasticity such as electrophysiological responsiveness and changes in gene expression may be examined in defined CNS regions as well as in single cells. The ability to simultaneously measure the mRNA levels for hundreds of different genes, to clone novel genes, a...

journal_title：Progress in brain research

authors： Eberwine J,Cao Y,Nair S,Miyashiro K,Mackler S,Finnell R,Surmeier J,Dichter M

更新日期：1995-01-01 00:00:00

abstract：:When an object partially or completely disappears behind an occluding surface, a representation of that object persists. For example, fragments of no longer visible objects can serve as an input into mid-level constructive visual processes, interacting and integrating with currently visible portions to form perceptual...

journal_title：Progress in brain research

authors： McCarthy JD,Erlikhman G,Caplovitz GP

更新日期：2017-01-01 00:00:00

abstract：:In our overview, we will attempt to justify the use of animal models and suggest that it is the only way to make the successive transitions between changes occurring at the molecular and cellular levels and changes at the level of behaviour in the intact organism. We will also stress the importance of criteria that ha...

journal_title：Progress in brain research

authors： Castellucci VF

更新日期：2008-01-01 00:00:00

abstract：:The following chapter offers an overview of results of experimental studies conducted among healthy individuals examining the effects of acute administration of Δ9-THC and other cannabinoids, alone or in combination, on brain function and behavior, also as a function of previous cannabis exposure. In light of their me...

journal_title：Progress in brain research

authors： Colizzi M,Bhattacharyya S

更新日期：2018-01-01 00:00:00

abstract：:While the role of attention in selecting visual attributes is well acknowledged, relatively less is known about the mechanisms that facilitate the selection of actions during goal-directed behaviors. The notion of an executive attention has provided a particularly fruitful framework to understand how the brain coordin...

journal_title：Progress in brain research

authors： Sharika KM,Ray S,Murthy A

更新日期：2009-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00

abstract：:The role of the superior colliculus in attending and orienting to sensory stimuli is facilitated by the presence within this midbrain nucleus of superimposed maps of different sensory modalities. We have studied the steps involved in the development of topographically-aligned maps of visual and auditory space in the f...

journal_title：Progress in brain research

authors： King AJ,Schnupp JW,Carlile S,Smith AL,Thompson ID

更新日期：1996-01-01 00:00:00

abstract：:The development of atherosclerotic cardiovascular disease is a common comorbidity in patients with the metabolic syndrome, a concurrence of cardiovascular risk factors in one individual. While multiple growth factors and adipokines are identified in atherosclerotic lesions, as well as neurotrophins implicated in both ...

journal_title：Progress in brain research

authors： Chaldakov GN,Fiore M,Stankulov IS,Manni L,Hristova MG,Antonelli A,Ghenev PI,Aloe L

更新日期：2004-01-01 00:00:00

abstract：:Parkinson's disease (PD) as a motor disorder is pathologically featured by the loss of dopaminergic neurons of the substantia nigra compacta (SNc) and the consequent depletion of dopamine in the striatum. However, motor signs are detectable when the loss of dopaminergic striatal terminals exceeds to the dopaminergic n...

journal_title：Progress in brain research

authors： Lafuente JV,Requejo C,Ugedo L

更新日期：2019-01-01 00:00:00

abstract：:GABAergic interneurons of the parvalbumin-positive fast-spiking basket cells subtype (PV INs) are important regulators of cortical network excitability and of gamma oscillations, involved in signal processing and cognition. Impaired development or function of PV INs has been associated with epilepsy in various animal ...

journal_title：Progress in brain research

authors： Jiang X,Lachance M,Rossignol E

更新日期：2016-01-01 00:00:00

abstract：:The serotonin (5-HT) neurotransmitter system provides fundamental modulatory regulation of the limbic-corticostriatal circuitry known to be vital in the development of addiction as well as the aspects of addiction that hinder recovery and contribute to relapse. Thus, components of the 5-HT system may provide novel tar...

journal_title：Progress in brain research

authors： Bubar MJ,Cunningham KA

更新日期：2008-01-01 00:00:00

abstract：:The role of the vesitibulo-cerebellum of the rabbit in the control of the vestibulo-ocular response (VOR) and optokinetic response (OKR) reflexes was investigated by bilateral microinjections, into the flocculus, of substances affecting GABAergic or noradrenergic neurotransmission. GABA, the main transmitter through w...

journal_title：Progress in brain research

authors： van Neerven J,Pompeiano O,Collewijn H

更新日期：1991-01-01 00:00:00

abstract：:Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression (CSD) is a wave of near-complete depolarization of neurons and glial cells that slowly propagates along the cortex creating the perception of aura. Evidence suggests that CSD can trigger migraine headache....

journal_title：Progress in brain research

authors： Takizawa T,Ayata C,Chen SP

更新日期：2020-01-01 00:00:00

abstract：:Otoacoustic emissions can be used to study cochlear function in an objective, non-invasive and rapid manner. These and other desirable features of emissions have inspired a significant amount of investigation into the practicalities of utilizing evoked emissions as clinical tests of hearing. Variables which affect the...

journal_title：Progress in brain research

authors： Lonsbury-Martin BL,Whitehead ML,Martin GK

更新日期：1993-01-01 00:00:00