Abstract：
:The role of the superior colliculus in attending and orienting to sensory stimuli is facilitated by the presence within this midbrain nucleus of superimposed maps of different sensory modalities. We have studied the steps involved in the development of topographically-aligned maps of visual and auditory space in the ferret superior colliculus. Injections of fluorescent beads into the superficial layers showed that the projection from the contralateral retina displays topographic order on the day of birth (PO). Recordings made from these layers at the time of eye opening, approximately 1 month later, revealed the presence of an adult-like map of visual space. In contrast, the auditory space map in the deeper layers emerged gradually over a much longer period of postnatal life. In adult ferrets in which one eye had been deviated laterally just before eye opening, the auditory spatial tuning of single units recorded in the contralateral superior colliculus was shifted by a corresponding amount, so that the registration of the visual and auditory maps was maintained. Chronic application of the NMDA-receptor antagonist MK801 disrupted the normal development of the auditory space map, but had no effect on the visual map in either juvenile or adult animals, or on the auditory map once it had matured. These findings indicate that visual cues may play an instructive role, possibly via a Hebbian mechanism of synaptic plasticity, in the development of appropriately tuned auditory responses, thereby ensuring that the neural representations of both modalities share the same coordinates. Changes observed in the auditory representation following partial lesions of the superficial layers at PO suggest that these layers may provide the source of the visual signals responsible for experience-induced plasticity in auditory spatial tuning.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
King AJ,Schnupp JW,Carlile S,Smith AL,Thompson IDdoi
10.1016/s0079-6123(08)63340-3subject
Has Abstractpub_date
1996-01-01 00:00:00pages
335-50eissn
0079-6123issn
1875-7855pii
S0079-6123(08)63340-3journal_volume
112pub_type
杂志文章abstract：:VLBW infants are at risk of lesions including intraventricular haemorrhage and periventricular leucomalacia. Those with normal IQ still present with reading difficulties. Oculomotor performance was assessed on 14 VLBWs (IQ > 85) and 15 full-term age-matched controls. Anti-saccade errors were significantly higher for t...
journal_title：Progress in brain research
pub_type： 临床试验,杂志文章
doi：10.1016/S0079-6123(02)40070-2
更新日期：2002-01-01 00:00:00
abstract：:The effects of endogenous metabolites of the neuropeptide vasopressin (VP) in behavioural tests led to the hypothesis that VP metabolites have a more selective function than VP. In contrast to VP, no peripheral effects have been found thus far with VP metabolites and their function seems to be associated with memory-r...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)61591-5
更新日期：1998-01-01 00:00:00
abstract：:In the past, medicine was dominated by acute diseases. Since treatments were unknown to patients they followed their medical doctors´ directives-at least for the duration of the disease. Behavior was thus largely motivated by avoiding expected costs associated with alternative behaviors (I-must). The health challenges...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2016.06.013
更新日期：2016-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53825-3.00017-6
更新日期：2011-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
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更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)61801-4
更新日期：1995-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
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更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)61141-3
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:Primary angle-closure glaucoma (PACG) is the leading cause of blindness in East Asia. The disease can be classified into primary angle-closure suspect, primary angle closure (PAC), and PACG. Pupil-block, anterior nonpupil-block (plateau iris and peripheral iris crowding), lens related and retrolenticular m...
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pub_type： 杂志文章
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更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(08)01134-5
更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
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更新日期：2007-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(08)00424-X
更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2018.07.009
更新日期：2018-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2018.09.011
更新日期：2018-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)62020-7
更新日期：2007-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2017.06.001
更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(05)50010-4
更新日期：2005-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,meta分析
doi：10.1016/S0079-6123(07)67028-9
更新日期：2008-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 传,历史文章,杂志文章
doi：10.1016/B978-0-444-62730-8.00006-2
更新日期：2013-01-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(10)84004-X
更新日期：2010-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(08)00926-6
更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62658-8
更新日期：1990-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(04)48025-X
更新日期：2005-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(04)47018-6
更新日期：2005-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53860-4.00011-8
更新日期：2012-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/B978-0-444-53860-4.00021-0
更新日期：2012-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/S0079-6123(08)00656-0
更新日期：2008-01-01 00:00:00
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journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53884-0.00015-4
更新日期：2011-01-01 00:00:00
abstract：:The target article describes an interesting study, which provides some challenging findings regarding athletes' pathway to excellence. The suggested links between critical life events, need for success, personal characteristics, and eventual performance level make sense from a psychodynamic perspective. This commentar...
journal_title：Progress in brain research
pub_type： 评论,杂志文章
doi：10.1016/bs.pbr.2017.02.004
更新日期：2017-01-01 00:00:00
