Prospects for serotonin 5-HT2R pharmacotherapy in psychostimulant abuse.

abstract：:Alzheimer's disease (AD), the most common type of adult-onset dementia, is characterized by a variety of brain abnormalities, including degeneration of certain populations of nerve cells, alterations in the neuronal cytoskeleton, and the abnormal deposition of amyloid within brain parenchyma. Pathogenetic processes th...

journal_title：Progress in brain research

authors： Price DL,Koo EH,Sisodia SS,Martin LJ,Koliatsos VE,Muma NA,Walker LC,Cork LC

更新日期：1990-01-01 00:00:00

abstract：:Activated microglia release a number of substances, the specific cocktail released depending on the stimulus. Many of the substances released by microglia also serve to activate them, suggesting the presence of a number of autocrine/paracrine loops. Because of the low density of microglia present in the normal brain, ...

journal_title：Progress in brain research

authors： Pocock JM,Liddle AC

更新日期：2001-01-01 00:00:00

abstract：:The midbrain has been shown to contain crucial nuclei for the control of vertical and torsional eye movements. Recent studies in monkeys demonstrated that midbrain lesions also affect head movements during gaze saccades, but so far clinical reports on the matter have been missing. We measured 3D eye and head movements...

journal_title：Progress in brain research

authors： Kremmyda O,Glasauer S,Eggert T,Büttner U

更新日期：2008-01-01 00:00:00

abstract：:Intracellular recordings from 103 photoreceptors in the excised pineal body of adult trouts were obtained by using single electrode current- and voltage-clamp techniques. The photoresponses to brief flashes showed the same polarity but a slower time course than those previously recorded from retinal photoreceptors of ...

journal_title：Progress in brain research

authors： Marchiafava PL,Kusmic C

更新日期：1993-01-01 00:00:00

abstract：:Recent eye-tracking research has revealed that spoken language can guide eye gaze very rapidly (and closely time-locked to the unfolding speech) toward referents in the visual world. We discuss whether, and to what extent, such language-mediated eye movements are automatic rather than subject to conscious and controll...

journal_title：Progress in brain research

authors： Mishra RK,Olivers CN,Huettig F

更新日期：2013-01-01 00:00:00

abstract：:Gamma aminobutyric acid (GABA) is an inhibitor neurotransmitter that plays many important roles in the central nervous system. Because the half-life time of GABA is very short in vivo, GABA itself is not used for clinical practice. An analogue of GABA, baclofen, is an agonist of GABA-B receptor, and has very strong an...

journal_title：Progress in brain research

authors： Taira T

更新日期：2009-01-01 00:00:00

abstract：:This chapter summarizes the most recent data on the use of the somatostatin analogues (SSAs), octreotide (OCT) and lanreotide for the treatment of patients with pituitary and neuroendocrine tumors (NETs). These two analogues have a high affinity for somatostatin receptor (SSR) sub-types 2 and 5. The major indications ...

journal_title：Progress in brain research

authors： Colao A,Faggiano A,Pivonello R

更新日期：2010-01-01 00:00:00

abstract：:Unraveling the mysteries of consciousness, lost and regained, and perhaps even intervening so as to prompt recovery are advances for which neither the clinical nor the lay community are prepared. These advances will shake existing expectations about severe brain damage and will find an unprepared clinical context, per...

journal_title：Progress in brain research

authors： Fins JJ

更新日期：2005-01-01 00:00:00

abstract：:The main topic of this overview is an analysis of the concepts of phase and synchrony, as used in neurophysiology, in their various meanings. A number of notions related to the concepts of phase and synchrony, which are incorporated in contemporary neurophysiology, particularly in the domain of neuro-cognitive physiol...

journal_title：Progress in brain research

authors： Lopes da Silva FH

更新日期：2006-01-01 00:00:00

abstract：:Experimental investigations of the lumbar sympathetic outflow to skin, skeletal muscle and viscera and the thoracic sympathetic outflow to the head and neck have shown that each target organ and tissue is supplied by one or two separate pathways which consists of sets of pre- and postganglionic neurons with distinct p...

journal_title：Progress in brain research

authors： Jänig W,Häbler HJ

更新日期：2000-01-01 00:00:00

abstract：:Two cortical areas that crucially contribute to the generation and maintenance of smooth pursuit eye movements (SPEM) are the medial superior temporal area (MST) and the pursuit area of the frontal eye fields (FEF). They both project to the brainstem premotor structures via different parallel pathways. A special prope...

journal_title：Progress in brain research

authors： Nuding U,Ono S,Mustari MJ,Büttner U,Glasauer S

更新日期：2008-01-01 00:00:00

abstract：:Immunoreactive oxytocin (OXT) detected in extracts of human coeliac ganglia and nn. vagi was characterized by high-performance liquid chromatography (HPLC). HPLC/RIA examinations demonstrated that a major part of the immunoreactive material in both investigated areas co-eluted with a reference synthetic OXT, but in th...

journal_title：Progress in brain research

authors： Vecsernyés M,Jójárt I,Jójárt J,Laczi F

更新日期：1992-01-01 00:00:00

abstract：:Parkinson's disease (PD) as a motor disorder is pathologically featured by the loss of dopaminergic neurons of the substantia nigra compacta (SNc) and the consequent depletion of dopamine in the striatum. However, motor signs are detectable when the loss of dopaminergic striatal terminals exceeds to the dopaminergic n...

journal_title：Progress in brain research

authors： Lafuente JV,Requejo C,Ugedo L

更新日期：2019-01-01 00:00:00

abstract：:Antidepressants are commonly prescribed for tinnitus. Research thus far provides some support for that treatment, but the literature also raises concerns because tinnitus is a side effect of antidepressant medication. In this chapter, four published double blind placebo-controlled trials of antidepressants for tinnitu...

journal_title：Progress in brain research

authors： Robinson S

更新日期：2007-01-01 00:00:00

abstract：:The quantitative autoradiographic method with L-(35S)methionine was applied to investigate the effect of chronic dehydration on rates of protein synthesis in circumventricular organs (CVOs). Water deprivation for 1, 2 and 3 days causes progressive increases of protein synthesis in the subfornical organ (SFO), the area...

journal_title：Progress in brain research

authors： Lepetit P,Grange E,Gay N,Bobillier P

更新日期：1992-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:Findings on nonprimate mammals place the issue of mother-infant lateralized relations in a broader context, demonstrating that humans are one of many species showing this feature. The remarkable interspecies consistency in the direction of lateralization points to a continuity between lateralized mother-infant interac...

journal_title：Progress in brain research

authors： Karenina K,Giljov A

更新日期：2018-01-01 00:00:00

abstract：:Acute spinal cord injury (SCI) is a devastating neurological disorder that can affect any individual at a given instance. Current treatment options for SCI include the use of high dose methylprednisolone sodium succinate, a corticosteroid, surgical interventions to stabilize and decompress the spinal cord, intensive m...

journal_title：Progress in brain research

authors： Baptiste DC,Fehlings MG

更新日期：2007-01-01 00:00:00

abstract：:An unresolved issue in visual motion perception is how distinct are the processes underlying 'first-order' and 'second-order' motion. The former is defined by spatio-temporal variations of luminance and the latter by spatio-temporal variations in other image attributes such as contrast or depth, for example. Using neu...

journal_title：Progress in brain research

authors： Vaina LM,Soloviev S

更新日期：2004-01-01 00:00:00

abstract：:Regaining any locomotor function after spinal cord injury is not only of immediate importance for affected patients but also for clinical research as it allows to investigate mechanisms underlying motor impairment and locomotor recovery. Clinical scores inform on functional outcomes that are clinically meaningful to v...

journal_title：Progress in brain research

authors： Awai L,Curt A

更新日期：2015-01-01 00:00:00

abstract：:Large-scale neural simulations have the marks of a distinct methodology which can be fruitfully deployed in neuroscience. I distinguish between two types of applications of the simulation methodology in neuroscientific research. Model-oriented applications aim to use the simulation outputs to derive new hypotheses abo...

journal_title：Progress in brain research

authors： Serban M

更新日期：2017-01-01 00:00:00

abstract：:Although circannual rhythms controlling different physiological processes and various aspects of behavior have been reported in numerous organisms, our understanding of the underlying biological mechanisms is still quite limited. We examined the mechanisms controlling the circannual pupation rhythm of the varied carpe...

journal_title：Progress in brain research

authors： Miyazaki Y,Nisimura T,Numata H

更新日期：2012-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00

abstract：:In the target article, Hardy and colleagues provided an incisive analysis of retrospectively reported psychosocial factors associated with the development and careers of 32 former athletes from Olympic sports. They found that Super-Elite athletes ("serial" medal winners at major international championships, i.e., Worl...

journal_title：Progress in brain research

authors： Gucciardi DF

更新日期：2017-01-01 00:00:00

abstract：:Sub-lethal exposure to practically any harmful stimulus has been shown to induce consequent protection against more severe stress. This preconditioning (PC) effect may be achieved by exposure to different stressors, indicating that the induction of tolerance involves activation of common protective pathways. Chronic e...

journal_title：Progress in brain research

authors： Shein NA,Horowitz M,Shohami E

更新日期：2007-01-01 00:00:00

abstract：:The studies reviewed in this chapter present a convincing argument that prostaglandins have direct actions at the level of the spinal cord to enhance nociception. Furthermore, an increasing body of evidence supports the hypothesis that one important site of action of these eicosanoids is the terminals of sensory neuro...

journal_title：Progress in brain research

authors： Vasko MR

更新日期：1995-01-01 00:00:00

abstract：:This chapter describes current findings from the research into postoperative cognitive dysfunction (POCD) following cardiac and non-cardiac surgery in older adults. The evidence suggests that a significant proportion of patients show POCD in the early weeks following surgery and anesthesia. Specific domains of cogniti...

journal_title：Progress in brain research

authors： Caza N,Taha R,Qi Y,Blaise G

更新日期：2008-01-01 00:00:00

abstract：:When an object partially or completely disappears behind an occluding surface, a representation of that object persists. For example, fragments of no longer visible objects can serve as an input into mid-level constructive visual processes, interacting and integrating with currently visible portions to form perceptual...

journal_title：Progress in brain research

authors： McCarthy JD,Erlikhman G,Caplovitz GP

更新日期：2017-01-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) studies performed during both waking rest and sleep show that the brain is continually active in distinct patterns that appear to reflect its underlying functional connectivity. In this review, potential sources that contribute to spontaneous fMRI activity will be discussed...

journal_title：Progress in brain research

authors： Duyn J

更新日期：2011-01-01 00:00:00

abstract：:The study of chimeric retinas has yielded insight on the early development of retina. The close match in chimerism ratios between right and left retinas is significant and supports the idea that both retinas originate from a common population of progenitors. We are able to estimate numbers of progenitor cells that con...

journal_title：Progress in brain research

authors： Goldowitz D,Rice DS,Williams RW

更新日期：1996-01-01 00:00:00