Abstract：
:Two cortical areas that crucially contribute to the generation and maintenance of smooth pursuit eye movements (SPEM) are the medial superior temporal area (MST) and the pursuit area of the frontal eye fields (FEF). They both project to the brainstem premotor structures via different parallel pathways. A special property of the pursuit system is the increased sensitivity to retinal image motion for increasing pursuit velocities (dynamic gain control), which might be attributed to the FEF. On the other hand, MST is regarded as the main site for estimating the target velocity in space and therefore for maintaining an ongoing SPEM. However, neural activities in these areas during visually driven SPEM have not been fully understood. We present a simple model of smooth pursuit gain control that comprises population activities, as well as single unit sensitivities with respect to eye and retinal image motion in MST and FEF. We show that the nonlinear computation necessary for dynamic gain control may be accomplished by units that exhibit a curvilinear sensitivity to retinal image motion and eye velocity.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Nuding U,Ono S,Mustari MJ,Büttner U,Glasauer Sdoi
10.1016/S0079-6123(08)00636-5subject
Has Abstractpub_date
2008-01-01 00:00:00pages
261-4eissn
0079-6123issn
1875-7855pii
S0079-6123(08)00636-5journal_volume
171pub_type
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