Abstract：
:The quantitative autoradiographic method with L-(35S)methionine was applied to investigate the effect of chronic dehydration on rates of protein synthesis in circumventricular organs (CVOs). Water deprivation for 1, 2 and 3 days causes progressive increases of protein synthesis in the subfornical organ (SFO), the area postrema, the organum vasculosum laminae terminalis and the neurohypophysis. Chronic salt ingestion with 2% NaCl in drinking water for 3 days resulted in increases of protein synthesis in the CVOs similar to those found after 3 days water deprivation, with only one exception, the SFO, in which the rise in protein synthesis was of lower amplitude after 3 days salt ingestion as compared to 3 days water deprivation. These results suggest that several circulating factors related to intracellular dehydration and the high plasma levels of the neurohormones vasopressin and oxytocin are probably important determinants of the rise of protein synthesis in circumventricular organs. Alternatively, the elevated level of blood-borne angiotensin II may well explain the higher metabolic response of the SFO following water deprivation compared to salt ingestion.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Lepetit P,Grange E,Gay N,Bobillier Pdoi
10.1016/s0079-6123(08)62363-8subject
Has Abstractpub_date
1992-01-01 00:00:00pages
435-8eissn
0079-6123issn
1875-7855pii
S0079-6123(08)62363-8journal_volume
91pub_type
杂志文章abstract：:PTSD arises by definition as a direct consequence of the experience of an acute severe stressor. The formation of traumatic memory and its extinction, sympathetic and adrenocortical stress systems activity in relation to individual vulnerability form the core of animal models for PTSD. ...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(07)67008-3
更新日期：2008-01-01 00:00:00
abstract：:Concerted efforts are realizing cell-based therapy for Parkinson's disease (PD). In this chapter, I describe efforts at the Center for iPS Cell Research and Application (CiRA), Kyoto University. These efforts use induced pluripotent stem cells (iPSCs) as donor cells. The iPSCs were established as human leukocyte antig...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2016.11.004
更新日期：2017-01-01 00:00:00
abstract：:By blocking electrical activity in the cerebellar cortex the Purkinje cell dendrites become a uniform territory with a high density of spines all bearing the glutamate receptor delta2 subunit (GluRdelta2) and being mainly innervated by parallel fibers. Such a subunit, which is constitutively targeted specifically to t...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(04)48005-4
更新日期：2005-01-01 00:00:00
abstract：:Immunoreactive oxytocin (OXT) detected in extracts of human coeliac ganglia and nn. vagi was characterized by high-performance liquid chromatography (HPLC). HPLC/RIA examinations demonstrated that a major part of the immunoreactive material in both investigated areas co-eluted with a reference synthetic OXT, but in th...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62321-3
更新日期：1992-01-01 00:00:00
abstract：:Individual differences in cognitive functioning during extended work hours and shift work are of considerable magnitude, and observed both in the laboratory and in the workplace. These individual differences have a biological basis in trait-like, differential vulnerability to fatigue from sleep loss and circadian misa...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/B978-0-444-53817-8.00009-8
更新日期：2011-01-01 00:00:00
abstract：:The organization of key molecules at glutamatergic synapses in the rat cerebellar cortex as analyzed by high resolution immunocytochemical techniques using gold particles as markers. The distinct compartmentation of glutamate and glutamine was consistent with biochemical data indicating an active role of glia in the r...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)63360-9
更新日期：1997-01-01 00:00:00
abstract：:Over the past three decades, developmental neurobiologists have made tremendous progress in defining basic principles of brain development. This work has changed the way we think about how brains develop. Thirty years ago, the dominant model was strongly deterministic. The relationship between brain and behavioral dev...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53884-0.00015-4
更新日期：2011-01-01 00:00:00
abstract：:Social cognitive skills play a crucial role in human life, and have allowed us to reach a unique level of behavioral and cultural complexity. However, many nonhuman species also show a complex understanding of the social world. Building on theories of human social development, we will follow the emergence of cultural ...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2020.05.008
更新日期：2020-01-01 00:00:00
abstract：:In this chapter, the distribution of Hsp70 in brain cell types following whole body hyperthermia is reviewed. The prevalence of Hsp70 expression in oligodendrocytes, microglia, and vascular cells in this type of stress contrasts with scarcity of Hsp70 induction in astrocytes and most neurons of the hyperthermic brain....
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)62020-7
更新日期：2007-01-01 00:00:00
abstract：:The ecological dynamics approach offers new insights to understand how athlete nervous systems are embedded within the body-environment system in sport. Cognitive neuroscience focuses on the neural bases of athlete behaviors in terms of perceptual, cognitive, and motor functions defined within specific brain structure...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2017.06.001
更新日期：2017-01-01 00:00:00
abstract：:Research points to the notion that athletes have the potential to benefit from difficulty. This phenomenon-otherwise known as growth following adversity-has attracted increasing attention from sport psychology scholars. In this paper, we systematically review and synthesize the findings of studies in this area to bett...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2017.06.002
更新日期：2017-01-01 00:00:00
abstract：:The arts can provide unique ways for determining how people not directly involved in medicine were viewing and informing others about physical and mental disorders. With operas, one need only think about how various perturbations of madness have been portrayed. Somnambulism has long been a particularly perplexing diso...
journal_title：Progress in brain research
pub_type： 历史文章,杂志文章
doi：10.1016/bs.pbr.2014.11.015
更新日期：2015-01-01 00:00:00
abstract：:The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy. The overall objective o...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/B978-0-444-53815-4.00011-X
更新日期：2011-01-01 00:00:00
abstract：:Neuronal activity increases synthesis of brain-derived neurotrophic factor (BDNF) mRNA in vivo and in vitro. We have investigated the pathways through which neuronal activity stimulated by kainic acid regulates BDNF mRNA levels in cultured hippocampal neurons and transgenic mice. Kainic acid induced the transcription ...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)64007-8
更新日期：1998-01-01 00:00:00
abstract：:Paired organotypic explants from rat occipital cortex were cultured for up to three weeks in the presence of selective blockers of amino acid receptor blockers, during which period spontaneous action potential generation was monitored electrophysiologically. In contrast to isolated explants (Corner, M.A., van Pelt, J....
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(04)47018-6
更新日期：2005-01-01 00:00:00
abstract：:The description of a biological system using a mathematical model is the most effective means to specify the functioning of a quantitative hypothesis, providing at the same time the ability to make predictions that can be further tested experimentally. The Vestibulo-Ocular Reflex (VOR), and more generally the ocular m...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2019.04.030
更新日期：2019-01-01 00:00:00
abstract：:The nervous system can generate rhythms of various frequencies; on the low-frequency side, we have the circuits regulating circadian rhythms with a 24-h period, while on the high-frequency side we have the motor circuits that underlie flight in a hummingbird. Given the ubiquitous nature of rhythms, it is surprising th...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-53613-6.00004-6
更新日期：2010-01-01 00:00:00
abstract：:Basic tendencies to detect and respond to significant events are present in the simplest single cell organisms and persist throughout all invertebrates and vertebrates. Within vertebrates, the overall brain plan is highly conserved, though differences in size and complexity also exist. The forebrain differs the most b...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/B978-0-444-53860-4.00021-0
更新日期：2012-01-01 00:00:00
abstract：:Compensatory electromyographic (EMG) responses and several biomechanical parameters were studied following impulsive disturbance of the limbs during stance of human volunteers on a treadmill. Treadmill acceleration impulses were backwards or forwards directed, or their initial direction was reversed after 30 ms. Backw...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/s0079-6123(08)62238-4
更新日期：1989-01-01 00:00:00
abstract：:Much of the past research on how reward motivation and emotional information influence brain and behavior has been conducted separately. Recently, a few behavioral and brain imaging studies have investigated how reward and emotional information co-jointly impact brain and behavior. The present chapter reviews findings...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2019.03.023
更新日期：2019-01-01 00:00:00
abstract：:Deficits in motivation are at the core of many neuropsychiatric disorders, including major depressive disorder (MDD). Research in MDD has been heavily focused on anhedonia and depression or negative/positive symptoms of depression, with less research attention focused on the dysregulation of motivational processes. Op...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/bs.pbr.2018.07.009
更新日期：2018-01-01 00:00:00
abstract：:The Tibetan Buddhist classification of mind, its divisions and the system of meditation practices aimed at achieving ideal states of being are a complex presentation of psychological, behavioral and spiritual concepts and processes that demand thorough understanding before assessing their value and outcome (Yeshe, 199...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)62160-3
更新日期：2000-01-01 00:00:00
abstract：:A computational model of the mammalian spinal cord circuitry incorporating a two-level central pattern generator (CPG) with separate half-center rhythm generator (RG) and pattern formation (PF) networks is reviewed. The model consists of interacting populations of interneurons and motoneurons described in the Hodgkin-...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(06)65015-2
更新日期：2007-01-01 00:00:00
abstract：:While a basic locomotor rhythm is centrally generated by spinal circuits, descending pathways are critical for ensuring appropriate anticipatory modifications of gait to accommodate uneven terrain. Neurons in the motor cortex command the changes in muscle activity required to modify limb trajectory when stepping over ...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(03)43025-2
更新日期：2004-01-01 00:00:00
abstract：:This chapter reviews the neurological phenotype of Down syndrome (DS) in early development, childhood, and aging. Neuroanatomic abnormalities in DS are manifested as aberrations in gross brain structure as well as characteristic microdysgenetic changes. As the result of these morphological abnormalities, brain circuit...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/B978-0-444-54299-1.00006-6
更新日期：2012-01-01 00:00:00
abstract：:Motor control is defined as the process of restricting the output of the motor nervous system so that meaningful and coordinated behavior ensues. The high dimensionality of the computation underlying motor control is presented and a simplifying framework is outlined. Evidence that movements are performed non-continuou...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)63380-4
更新日期：1997-01-01 00:00:00
abstract：:The idea of the dentate gyrus as a gate or filter at the entrance to the hippocampus, blocking or filtering incoming excitation from the entorhinal cortex, has been an intriguing one. Here we review the historical development of the idea, and discuss whether it may be possible to be more specific in defining this gate...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/S0079-6123(07)63032-5
更新日期：2007-01-01 00:00:00
abstract：:Large-scale neural simulations have the marks of a distinct methodology which can be fruitfully deployed in neuroscience. I distinguish between two types of applications of the simulation methodology in neuroscientific research. Model-oriented applications aim to use the simulation outputs to derive new hypotheses abo...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2017.05.004
更新日期：2017-01-01 00:00:00
abstract：:Cognitive neuroscience is currently finding itself as a marketing trend in occupational science, particularly in terms of workplace assessment and measurement. However, the field has historically had little to do with occupational applications and has generally remained focused on the clinical and academic relevance o...
journal_title：Progress in brain research
pub_type： 杂志文章
doi：10.1016/bs.pbr.2020.05.032
更新日期：2020-01-01 00:00:00
abstract：:Alzheimer's disease (AD), the most common type of adult-onset dementia, is characterized by a variety of brain abnormalities, including degeneration of certain populations of nerve cells, alterations in the neuronal cytoskeleton, and the abnormal deposition of amyloid within brain parenchyma. Pathogenetic processes th...
journal_title：Progress in brain research
pub_type： 杂志文章,评审
doi：10.1016/s0079-6123(08)63186-6
更新日期：1990-01-01 00:00:00
