Abstract:
:The nervous system can generate rhythms of various frequencies; on the low-frequency side, we have the circuits regulating circadian rhythms with a 24-h period, while on the high-frequency side we have the motor circuits that underlie flight in a hummingbird. Given the ubiquitous nature of rhythms, it is surprising that we know very little of the cellular and molecular mechanisms that produce them in the embryos and of their potential role during the development of neuronal circuits. Recently, zebrafish has been developed as a vertebrate model to study the genetics of neural development. Zebrafish offer several advantages to the study of nervous system development including optical and electrophysiological analysis of neuronal activity even at the earliest embryonic stages. This unique combination of physiology and genetics in the same animal model has led to insights into the development of neuronal networks. This chapter reviews work on the development of zebrafish motor rhythms and speculates on birth and maturation of the circuits that produce them.
journal_name
Prog Brain Resjournal_title
Progress in brain researchauthors
Saint-Amant Ldoi
10.1016/B978-0-444-53613-6.00004-6subject
Has Abstractpub_date
2010-01-01 00:00:00pages
47-61eissn
0079-6123issn
1875-7855pii
B978-0-444-53613-6.00004-6journal_volume
187pub_type
杂志文章,评审abstract::A persistent nineteenth-century urban legend was the notion that photograph-like images of the last-seen object or person would be preserved in the eyes of the dead. This popular notion followed technological developments (the daguerreotype and ophthalmoscope) that antedated by decades a basic understanding of retinal...
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pub_type: 历史文章,杂志文章
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pub_type: 评论,杂志文章
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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journal_title:Progress in brain research
pub_type: 传,历史文章,杂志文章
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