Microglial signalling cascades in neurodegenerative disease.

abstract：:The serotonin (5-HT) neurotransmitter system provides fundamental modulatory regulation of the limbic-corticostriatal circuitry known to be vital in the development of addiction as well as the aspects of addiction that hinder recovery and contribute to relapse. Thus, components of the 5-HT system may provide novel tar...

journal_title：Progress in brain research

authors： Bubar MJ,Cunningham KA

更新日期：2008-01-01 00:00:00

abstract：:Characteristic features of autism include atypical social perception and social-communication skills, and atypical visual attention, alongside rigid and repetitive thinking and behavior. Debate has focused on whether the later emergence of atypical social skills is a consequence of attention problems early in life, or...

journal_title：Progress in brain research

authors： Elsabbagh M,Holmboe K,Gliga T,Mercure E,Hudry K,Charman T,Baron-Cohen S,Bolton P,Johnson MH,BASIS Team.

更新日期：2011-01-01 00:00:00

abstract：:The two roles in awareness most often suggested for the cerebellum are (i) keeping the details of motor skills away from forebrain computation, and (ii) signaling to the forebrain when a sensory event is not predictable from prior motor commands. However, it is unclear how current models of the cerebellum could carry ...

journal_title：Progress in brain research

authors： Dean P,Porrill J,Stone JV

更新日期：2004-01-01 00:00:00

abstract：:A remarkable preparation for studying development and repair is the CNS of the newborn opossum which, removed in its entirety, survives in culture for more than 1 week. In suitable medium, cells continue to divide, mature and reflex activity is maintained. Moreover, nerve fibers grow rapidly, reliably and extensively ...

journal_title：Progress in brain research

authors： Nicholls JG,Vischer H,Varga Z,Erulkar S,Saunders NR

更新日期：1994-01-01 00:00:00

abstract：:Quantitative models of the oculomotor plant and control of the saccadic eye movement system are presented in this chapter. Oculomotor plant models described here are linear, including a second-order model by Westheimer (1954), Bahill et al. (1980) and Enderle et al. (2000). The model of the saccade generator is initia...

journal_title：Progress in brain research

authors： Enderle JD

更新日期：2002-01-01 00:00:00

abstract：:Partly due to the failure of anthropology to productively engage the fields of psychology and neuroscience, investigations in cultural neuroscience have occurred largely without the active involvement of anthropologists or anthropological theory. Dramatic advances in the tools and findings of social neuroscience have ...

journal_title：Progress in brain research

authors： Brown RA,Seligman R

更新日期：2009-01-01 00:00:00

abstract：:In the kidney, the actions of the antidiuretic hormone arginine vasopressin (AVP) renders the collecting duct highly permeable to water. This large increase in water permeability is largely due to the translocation of the water channel aquaporin-2 (AQP-2) from intracellular storage vesicles to the apical plasma membra...

journal_title：Progress in brain research

authors： Fenton RA,Moeller HB

更新日期：2008-01-01 00:00:00

abstract：:Schwann cells (SCs), when implanted in the injured spinal cord, support regeneration of axons, myelinate or ensheathe regenerated axons in a normal way, reduce cyst formation in the injured tissue, reduce secondary damage of tissue around the initial injury site, and modestly improve limb movements. If SC transplantat...

journal_title：Progress in brain research

authors： Wiliams RR,Bunge MB

更新日期：2012-01-01 00:00:00

abstract：:Postural instability and falls are common causes of morbidity and mortality in the second most prevalent neurodegenerative condition, Parkinson's disease (PD). Poor understanding of balance dysfunction in PD has hampered the development of novel therapeutic measures for postural instability and balance dysfunction. We...

journal_title：Progress in brain research

authors： Beylergil SB,Ozinga S,Walker MF,McIntyre CC,Shaikh AG

更新日期：2019-01-01 00:00:00

abstract：:The cytoarchitecture and the histochemistry of nucleus prepositus hypoglossi and its afferent and efferent connections to oculomotor structures are described. The functional significance of the afferent connections of the nucleus is discussed in terms of current knowledge of the firing behavior of prepositus neurons i...

journal_title：Progress in brain research

authors： McCrea RA,Horn AK

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Primary angle-closure glaucoma (PACG) is the leading cause of blindness in East Asia. The disease can be classified into primary angle-closure suspect, primary angle closure (PAC), and PACG. Pupil-block, anterior nonpupil-block (plateau iris and peripheral iris crowding), lens related and retrolenticular m...

journal_title：Progress in brain research

authors： Amerasinghe N,Aung T

更新日期：2008-01-01 00:00:00

abstract：:Network oscillations are proposed to provide the framework for the ongoing neural computations of the brain. Thus, an important aspect of understanding the functional roles of various cell classes in the brain is to understand the relationship of cellular activity to the ongoing oscillations. While many studies have c...

journal_title：Progress in brain research

authors： Henze DA,Buzsáki G

更新日期：2007-01-01 00:00:00

abstract：:Otoacoustic emissions can be used to study cochlear function in an objective, non-invasive and rapid manner. These and other desirable features of emissions have inspired a significant amount of investigation into the practicalities of utilizing evoked emissions as clinical tests of hearing. Variables which affect the...

journal_title：Progress in brain research

authors： Lonsbury-Martin BL,Whitehead ML,Martin GK

更新日期：1993-01-01 00:00:00

abstract：:Results reported here confirm and extend those of early retrograde transport studies of the brainstem in the rat and cat. This study demonstrates substantial and multiple afferent projections to the cat locus coeruleus arising from neurons containing acetylcholine, serotonin, norepinephrine, epinephrine, dopamine, his...

journal_title：Progress in brain research

authors： Sakai K

更新日期：1991-01-01 00:00:00

abstract：:The hypothalamic-neurohypophysial system undergoes dramatic morphological plasticity in response to physiological activation during parturition/lactation and dehydration, including somatic swelling, decreased glial coverage and increased synaptic innervation of the magnocellular neuroendocrine cells. Recent in-vitro e...

journal_title：Progress in brain research

authors： Tasker JG,Di S,Boudaba C

更新日期：2002-01-01 00:00:00

abstract：:The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscle...

journal_title：Progress in brain research

authors： Shefchyk SJ

更新日期：2002-01-01 00:00:00

abstract：:Oestrogens (E) influence the activity of oxytocin (OT) producing neurons and heighten the rate of transcription of the oxytocin receptor (OTR) gene. Working through synergistic activities of two different oestrogen receptors (ERs), likely gene duplication products, in the hypothalamus and amygdala, E supports social r...

journal_title：Progress in brain research

authors： Choleris E,Devidze N,Kavaliers M,Pfaff DW

更新日期：2008-01-01 00:00:00

abstract：:Modern philosophy of mind cannot be understood without recent developments in computer science, artificial intelligence (AI), robotics, neuroscience, biology, linguistics, and psychology. Classical philosophy of formal languages as well as symbolic AI assume that all kinds of knowledge must explicitly be represented b...

journal_title：Progress in brain research

authors： Mainzer K

更新日期：2008-01-01 00:00:00

abstract：:Neurons in the midbrain superior colliculus (SC) have the ability to integrate information from different senses to profoundly increase their sensitivity to external events. This not only enhances an organism's ability to detect and localize these events, but to program appropriate motor responses to them. The surviva...

journal_title：Progress in brain research

authors： Stein BE,Rowland BA

更新日期：2011-01-01 00:00:00

abstract：:Swallowing is an essential function in our daily life; nevertheless, stroke or other neurodegenerative diseases can cause the malfunction of swallowing function, ie, dysphagia. The objectives of this review are to understand the neural and cortical basis of swallowing and tongue, and review the latest techniques on th...

journal_title：Progress in brain research

authors： Yang H,Ang KK,Wang C,Phua KS,Guan C

更新日期：2016-01-01 00:00:00

abstract：:Motor control of different segments of the body with multiple degrees of freedom appears to be coordinated by utilizing preferred axes of motor activity. This hypothesis may also be applied to vestibular control of posture. To explore this question we studied the anatomical relationship between the head and the cervic...

journal_title：Progress in brain research

authors： Vidal PP,Wang DH,Graf W,de Waele C

更新日期：1993-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) research to date has focused almost exclusively on the pathophysiology of injured neurons with very little attention paid to non-neuronal cells. However in the past decade, exciting discoveries have challenged this century-old view of passive glial cells and have led to a reinterpretation ...

journal_title：Progress in brain research

authors： Floyd CL,Lyeth BG

更新日期：2007-01-01 00:00:00

abstract：:The ability to form tenable hypotheses regarding the neurobiological basis of normative functions as well as mechanisms underlying neurodegenerative and neuropsychiatric disorders is often limited by the highly complex brain circuitry and the cellular and molecular mosaics therein. The brain is an intricate structure ...

journal_title：Progress in brain research

authors： Ginsberg SD,Mirnics K

更新日期：2006-01-01 00:00:00

abstract：:Recent years have brought a rapid growth in knowledge of the prodromal phase of Parkinson's disease (PD). It is now clear that the clinical phase of PD is preceded by a phase of progressing neurodegeneration lasting many years. This involves not only central nervous system structures outside the substantia nigra and n...

journal_title：Progress in brain research

authors： Schaeffer E,Postuma RB,Berg D

更新日期：2020-01-01 00:00:00

abstract：:In order to study cerebral activity related to preparation and execution of movement, evoked and induced brain electrical activities were compared to each other and to fMRI results in voluntary self-paced movements. Also, the event-related desynchronization and synchronization (ERD/ERS) were studied in complex movemen...

journal_title：Progress in brain research

authors： Rektor I,Sochůrková D,Bocková M

更新日期：2006-01-01 00:00:00

abstract：:While the role of attention in selecting visual attributes is well acknowledged, relatively less is known about the mechanisms that facilitate the selection of actions during goal-directed behaviors. The notion of an executive attention has provided a particularly fruitful framework to understand how the brain coordin...

journal_title：Progress in brain research

authors： Sharika KM,Ray S,Murthy A

更新日期：2009-01-01 00:00:00

abstract：:It has been known for decades that females are more susceptible than men to inflammatory autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis, and psoriasis. In addition, female patients with these diseases experience clinical improvements during pregnancy with a temporary "rebound" exacerbatio...

journal_title：Progress in brain research

authors： Gold SM,Voskuhl RR

更新日期：2009-01-01 00:00:00

abstract：:John Bell, brother-surgeon of Charles Bell, was, like Charles, an outstanding surgeon and a good artist. John was one of the few who illustrated his work with their own drawings in the days before audiovisual aids were available and without the benefit of reliable drawing aids, photography and computer-aided design. C...

journal_title：Progress in brain research

authors： Gardner-Thorpe C

更新日期：2013-01-01 00:00:00

abstract：:1. Alzheimer's disease is a multifactorial disease in which age and APOE-epsilon 4 are important risk factors. Various mutations and even viral infections such as herpes simplex (Itzhaki et al., 1997) may play an additional role. 2. The neuropathological hallmarks of Alzheimer's disease (AD), i.e. amorphous plaques, n...

journal_title：Progress in brain research

authors： Swaab DF,Lucassen PJ,Salehi A,Scherder EJ,van Someren EJ,Verwer RW

更新日期：1998-01-01 00:00:00

abstract：:Using alternatively labelled (-)-deprenyl (3H label in the ring and 14C in the propargyl group) the distribution of the compound was studied in 15 brain regions and the plasma of rats over a period of 96 h, after oral administration of 1.5 mg/kg of (-)-deprenyl. The compound is rapidly absorbed (within 15-30 min) from...

journal_title：Progress in brain research

authors： Magyar K,Lengyel J,Szatmári I,Gaál J

更新日期：1995-01-01 00:00:00