Reduction in DNA synthesis during two-photon microscopy of intrinsic reduced nicotinamide adenine dinucleotide fluorescence.

abstract：:The crystal and molecular structure of the title compound 4 have been determined by single crystal X-ray crystallography. The structure shows the typical S4-ruffled conformation observed for Ni(II) tetrapyrroles. Compared to the structure of the methyl ester of (13(2)-demethoxycarbonyl-pheophorbidato a)nickel(II), 4 s...

journal_title：Photochemistry and photobiology

authors： Senge MO,Smith KM

更新日期：1994-08-01 00:00:00

abstract：:Organisms living in coastal waters are exposed to anthropogenic contaminants from terrestrial drainage, ice melting and maritime traffic and to enhanced UVB radiation (UVBR; 280-320 nm) caused by decreased concentrations of ozone in the stratosphere. This article reviews available information about the combined effect...

journal_title：Photochemistry and photobiology

authors： Pelletier E,Sargian P,Payet J,Demers S

更新日期：2006-07-01 00:00:00

abstract：:Polysulphone (PS) dosimetry has been a widely used technique for more than 30 years to quantify the erythemally effective UV dose received by anatomic sites (personal exposure). The calibration of PS dosimeters is an important issue as their spectral response is different from the erythemal action spectrum. It is perf...

journal_title：Photochemistry and photobiology

authors： Casale GR,Siani AM,Diémoz H,Kimlin MG,Colosimo A

更新日期：2012-01-01 00:00:00

abstract：:During the photoreaction cycle of photoactive yellow protein (PYP), a physiologically active intermediate (PYP(M)) is formed as a consequence of global protein conformational change. Previous studies have demonstrated that the photocycle of PYP is regulated by the N-terminal loop region, which is located across the ce...

journal_title：Photochemistry and photobiology

authors： Harigai M,Kataoka M,Imamoto Y

更新日期：2008-07-01 00:00:00

abstract：:Photodynamic therapy (PDT) of solid tumors elicits a strong, acute inflammatory response characterized by a rapid and massive infiltration of activated neutrophils into the tumor. The present study investigated the impact of PDT on the systemic and local (treatment site) kinetics of neutrophil trafficking and activity...

journal_title：Photochemistry and photobiology

authors： Cecic I,Parkins CS,Korbelik M

更新日期：2001-11-01 00:00:00

abstract：:To determine the origin of the UV-specific CC to TT tandem mutation at the CC site, we made a duplex DNA decamer containing a uracil cis-syn cyclobutane dimer (CBD) as the deaminated model of a cytosine dimer. Two-dimensional 1H-NMR spectroscopy studies were performed on this sequence where two adenines (Ade) were opp...

journal_title：Photochemistry and photobiology

authors： Lee HM,Kim JK

更新日期：2002-10-01 00:00:00

abstract：:Eumelanin (brown/black melanin) and pheomelanin (red/yellow melanin) in human hair can be quantified using chemical methods or approximated using spectrophotometric methods. Chemical methods consume greater resources, making them less attractive for epidemiological studies. This investigation sought to identify the sp...

journal_title：Photochemistry and photobiology

authors： Shekar SN,Duffy DL,Frudakis T,Montgomery GW,James MR,Sturm RA,Martin NG

更新日期：2008-05-01 00:00:00

abstract：:The excited-state intramolecular H-atom transfer reactions of hypocrellins B and A are compared by using time-resolved absorption and fluorescence upconversion techniques. The hypocrellin B photophysics are well described by a simple model involving one ground-state species and excited-state forward and reverse H-atom...

journal_title：Photochemistry and photobiology

authors： Datta A,Smirnov AV,Wen J,Chumanov G,Petrich JW

更新日期：2000-02-01 00:00:00

abstract：:Endogenous reduced nicotinamide adenine dinucleotide (NADH) fluorescence provides an intrinsic indicator of the cellular metabolic state, but prolonged monitoring is limited by photobleaching and/or phototoxicity. Multiphoton excitation of NADH by ultrashort, 740-nm laser pulses provides a significant improvement over...

journal_title：Photochemistry and photobiology

authors： Tiede LM,Nichols MG

更新日期：2006-05-01 00:00:00

abstract：:The efficacy of photodynamic therapy (PDT) depends upon the amount of photosensitizer accumulated in the malignant tissues. Radachlorin is a popular photosensitizer used in photodynamic therapy to treat various types of cancer. In this study, we have studied the main organelles responsible for the accumulation of rada...

journal_title：Photochemistry and photobiology

authors： Biswas R,Moon JH,Ahn JC

更新日期：2014-09-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:The potential for electron transfer quenching of rose bengal triplet (3RB2-) to compete with energy transfer quenching by oxygen was evaluated. Rate constants for oxidative and reductive quenching were measured in buffered aqueous solution, acetonitrile and in small unilamellar liposomes using laser flash photolysis. ...

journal_title：Photochemistry and photobiology

authors： Lambert CR,Kochevar IE

更新日期：1997-07-01 00:00:00

abstract：:A new water-soluble porphyrin derivative, 2,4-bis(1-decyloxyethyl)-deuteroporphyrinyl-6,7-bisaspart ic acid (C10-DP), and its metal complexes (Ga, I(n), Zn, Mn, Cu, Ni and Fe) were examined for their physicochemical properties (absorption, fluorescence, triplet lifetime and partition coefficient) and photocytotoxicity...

journal_title：Photochemistry and photobiology

authors： Ando T,Irie K,Koshimizu K,Takemura T,Nishino H,Iwashima A,Takeda N,Nakajima S,Sakata I

更新日期：1993-04-01 00:00:00

abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

journal_title：Photochemistry and photobiology

authors： Sirangelo I,Irace G,Bismuto E

更新日期：1994-06-01 00:00:00

abstract：:It has previously been demonstrated that chronic low-dose solar-simulated UV radiation could induce both local and systemic immunosuppression as well as tolerance to a topically applied hapten. In this study, we have used a chronic low-dose UV-irradiation protocol to investigate the effects of UVA on the skin immune s...

journal_title：Photochemistry and photobiology

authors： Bestak R,Halliday GM

更新日期：1996-12-01 00:00:00

abstract：:Exposure of solutions containing both tryptophan and hydrogen peroxide to a pulsed ( approximately 180 fs) laser beam at 750 nm induces luminescence characteristic of 5-hydroxytryptophan. The results indicate that 3-photon excitation of tryptophan results in photoionization within the focal volume of the laser beam. T...

journal_title：Photochemistry and photobiology

authors： Bisby RH,Crisostomo AG,Botchway SW,Parker AW

更新日期：2009-01-01 00:00:00

abstract：:The phototransduction cascade is perhaps the best understood model system for G protein-coupled receptor (GPCR) signaling. Phototransduction links the absorption of a single photon of light to a decrease in cytosolic cGMP. Depletion of the cGMP pool induces closure of cGMP-gated cation channels resulting in the hyperp...

journal_title：Photochemistry and photobiology

authors： Lodowski DT,Angel TE,Palczewski K

更新日期：2009-03-01 00:00:00

abstract：:Previous studies with methylene blue (MB) in red cell suspensions have demonstrated that extracellular, but not intracellular, virus can be readily photoinactivated. To test if the resistance of intracellular virus to inactivation is related to the permanent positive charge of the phenothiazine, a series of uncharged ...

journal_title：Photochemistry and photobiology

authors： Skripchenko A,Robinette D,Wagner SJ

更新日期：1997-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a way of treating malignant tumors and hyperproliferative diseases. It is based on the use of photosensitizer, herein the chlorophyll a (chl a), and a light of an appropriate wavelength. The interaction of the photosensitizer (PS) with the light produces reactive oxygen species (ROS), pow...

journal_title：Photochemistry and photobiology

authors： Cellamare BM,Fini P,Agostiano A,Sortino S,Cosma P

更新日期：2013-03-01 00:00:00

abstract：:The octahedral rhodium complex, cis-dichloro bis(1,10 phenanthroline)rhodium(III) chloride (BISPHEN), is known to form covalent linkages with DNA involving the attachment of the metal to a base. In order to determine the sequence selectivity of this chemistry, solutions of the complex containing one of the double-stra...

journal_title：Photochemistry and photobiology

authors： Morrison H,Harmon H

更新日期：2000-12-01 00:00:00

abstract：:In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Emodin is a naturally occurring anthraquinone which is ...

journal_title：Photochemistry and photobiology

authors： Rahimipour S,Bilkis I,Péron V,Gescheidt G,Barbosa F,Mazur Y,Koch Y,Weiner L,Fridkin M

更新日期：2001-08-01 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygote of the brown alga, Silvetia compressa. This effect is mediated by an increase in the intracellular concentration of guanosine 3', 5'-cyclic monophosphate. In this study we show the identification of a rhodopsin-like protein, by means of an...

journal_title：Photochemistry and photobiology

authors： Gualtieri P,Robinson KR

更新日期：2002-01-01 00:00:00

abstract：:The incidence of skin cancer is increasing rapidly, particularly in the Caucasian population. Epidemiological and experimental studies demonstrated that ultraviolet radiation (UVR) is the primary cause for the increasing incidence of skin cancer. It is well known that UV irradiation induces DNA damage. If the damage i...

journal_title：Photochemistry and photobiology

authors： Bush JA,Ho VC,Mitchell DL,Tron VA,Li G

更新日期：1999-09-01 00:00:00

abstract：:The exposure of outdoor car guards to solar ultraviolet radiation (UVR), the majority with deeply pigmented skin, to solar UVR was measured for five consecutive days during early spring (September 2017) in South Africa using electronic UVR dosimeters attached to the upper arm of each participant. The exposure of the n...

journal_title：Photochemistry and photobiology

authors： Nkogatse MM,Ramotsehoa MC,Eloff FC,Wright CY

更新日期：2019-01-01 00:00:00

abstract：:We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated...

journal_title：Photochemistry and photobiology

authors： Andreoni A,Colasanti A,Kisslinger A,Mastrocinque M,Portella G,Riccio P,Roberti G

更新日期：1993-05-01 00:00:00

abstract：:Light-dark cycles are considered important cues to entrain biological clocks. A feedback loop of clock gene transcription and translation is the molecular basis underlying the mechanism of both central and peripheral clocks. Xenopus laevis embryonic melanophores respond to light with melanin granule dispersion, respon...

journal_title：Photochemistry and photobiology

authors： Magalhães Moraes MN,de Oliveira Poletini M,Ribeiro Ramos BC,de Lima LH,de Lauro Castrucci AM

更新日期：2014-05-01 00:00:00

abstract：:Polarized steady-state fluorescence and fluorescence excitation spectra as well as time-resolved fluorescence for B-phycoerythrin (B-PE) from red algae, Porphyridium cruentum, embedded in polyvinyl stretched films were measured. The lifetimes of polarized fluorescence were analyzed using exponential components and fra...

journal_title：Photochemistry and photobiology

authors： Frackowiak D,Ptak A,Gryczynski Z,Gryczynski I,Targowski P,Zelent B

更新日期：2004-01-01 00:00:00

abstract：:Pyrimidine dimers were measured in epidermal DNA of SKH:HR1 mice following exposure to solar-simulated UV radiation (SSUV, 290-400 nm) or to UVA (320-400 nm). Mice were exposed to SSUV or UVA after topical application (2 mg/cm2) of vehicle, a UVB absorber (5% 2-ethylhexyl p-methoxycinnamate [2-EHMC]), or a broad-spect...

journal_title：Photochemistry and photobiology

authors： Ley RD,Fourtanier A

更新日期：1997-06-01 00:00:00

abstract：:It was shown that psoralen + UV-A inhibits the chemotactic activity of polymorphonuclear neutrophils towards anaphylatoxin C5a des Arg. This reaction required oxygen and there is a high possibility that the active oxygen species was in a singlet state. Oxygen did not act directly on C5a des Arg, but rather produced ox...

journal_title：Photochemistry and photobiology

authors： Esaki K,Mizuno N

更新日期：1992-05-01 00:00:00

abstract：:Analysis of phosphorescence lifetimes using the Stern-Volmer equation is a reliable means of determining quencher concentration for a uniform sample. Methods of analysis for heterogeneous systems are based on the assumption that the excitation is produced by a momentary flash. This condition is an idealization because...

journal_title：Photochemistry and photobiology

authors： Golub AS,Popel AS,Zheng L,Pittman RN

更新日期：1999-06-01 00:00:00