Effect of psoralen + ultraviolet-A on the chemotactic activity of polymorphonuclear neutrophils towards anaphylatoxin C5a des Arg.


:It was shown that psoralen + UV-A inhibits the chemotactic activity of polymorphonuclear neutrophils towards anaphylatoxin C5a des Arg. This reaction required oxygen and there is a high possibility that the active oxygen species was in a singlet state. Oxygen did not act directly on C5a des Arg, but rather produced oxidized psoralen which inhibited C5a des Arg activity. The effect was dependent on the concentration and types of psoralen and on the UV-A dose. Among the psoralens, the inhibitory effect of 4,5',8-trimethylpsoralen was the strongest, followed by 8-methoxypsoralen and 3-carbethoxypsoralen and finally 4,4',6-trimethylangelicin. Psoralen + UV-A failed to inhibit the chemotactic activity towards chemotactants other than anaphylatoxin C5a such as casein, the cultured filtrate of E. coli, platelet-activating factor, leukotriene B4, 5-hydroxy-6,8,11,14-eicosatetraenoic acid and 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.


Photochem Photobiol


Esaki K,Mizuno N


Has Abstract


1992-05-01 00:00:00












  • Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

    abstract::Ultraviolet (UV) radiation is among the most prevalent environmental factors that influence human health and disease. Even 1 h of UV irradiation extensively damages the genome. To cope with resulting deleterious DNA lesions, cells activate a multitude of DNA damage response pathways, including DNA repair. Strikingly, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Lee JW,Ratnakumar K,Hung KF,Rokunohe D,Kawasumi M

    更新日期:2020-05-01 00:00:00

  • In vitro photodynamic effects of lysyl chlorin p6: cell survival, localization and ultrastructural changes.

    abstract::The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

    更新日期:1993-11-01 00:00:00

  • Laser thermal ablation.

    abstract::Continuous wave and pulsed laser ablation of tissue is described as an explosive event. A subsurface temperature maximum and superheated tissue produce high pressures that eject fragments from the tissue. Decreased water content due to dehydration and vaporization decreases thermal conductivity which reduces heat cond...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Welch AJ,Motamedi M,Rastegar S,LeCarpentier GL,Jansen D

    更新日期:1991-06-01 00:00:00

  • Influence of human serum albumin on photodegradation of folic acid in solution.

    abstract::It has been proposed that photodegradation of folates may be the reason for the pigmentation of races living under high fluence rates of ultraviolet radiation. The photodegradation of folic acid (FA) induced by ultraviolet-A (UV-A) radiation, in solution and in the presence of human serum albumin (HSA), was studied wi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Vorobey P,Steindal AE,Off MK,Vorobey A,Moan J

    更新日期:2006-05-01 00:00:00

  • Application of CdTe/ZnSe quantum dots in in vitro imaging of chicken tissue and embryo.

    abstract::The present work is aimed to synthesize CdTe/ZnSe core/shell quantum dots (QDs) in an easy way and to explore the possibilities of its application in in vitro imaging of chicken tissue and embryo. The QDs were prepared using microwave irradiation with different temperatures, which is a very easy and less time-consumin...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Moulick A,Blazkova I,Milosavljevic V,Fohlerova Z,Hubalek J,Kopel P,Vaculovicova M,Adam V,Kizek R

    更新日期:2015-03-01 00:00:00

  • Decay kinetics of benzophenone triplets and corresponding free radicals in soft and rigid polymers studied by laser flash photolysis.

    abstract::The kinetics of transients formed under photoexcitation of benzophenone (B) dissolved in three different polymers was studied by ns laser flash photolysis. These polymers were the soft rubbers poly (ethylene-co-butylene) (EB), polystyrene block-poly(ethylene-ran-butylene)-block-polystyrene (SEBS) and hard polystyrene ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Levin PP,Efremkin AF,Sultimova NB,Kasparov VV,Khudyakov IV

    更新日期:2014-03-01 00:00:00

  • Intracellular target for alpha-terthienyl photosensitization: involvement of lysosomal membrane damage.

    abstract::Intracellular targets for the photosensitizer alpha-terthienyl (alpha T) were examined by fluorescence microscopy and microfluorospectrometry using human nonkeratinized buccal cells. Intracellular distribution of alpha T was observed as fluorescent patches widely dispersed in the cytoplasm. The distribution of the flu...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Sasaki M,Koyama S,Tokiwa K,Fujita H

    更新日期:1993-05-01 00:00:00

  • The hairless mouse model of photoaging: evaluation of the relationship between dermal elastin, collagen, skin thickness and wrinkles.

    abstract::Quantitative and qualitative changes in dermal collagen and elastin occur in response to chronic ultraviolet (UV) irradiation. These changes have been implicated in the genesis of the wrinkling seen in chronically irradiated, or photoaged skin. We examined the relationship between wrinkle formation and changes in derm...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Moloney SJ,Edmonds SH,Giddens LD,Learn DB

    更新日期:1992-10-01 00:00:00

  • Dipole and oscillator strengths of chromophores in solution.

    abstract::A widely published expression for dipole strengths of optical transitions is found to require correction. The proposed adjustment, which involves the refractive index of the solvent in which the strengths are measured, may lead to significant changes in predictions that have been based on the equation. We discuss a cl...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Knox RS

    更新日期:2003-05-01 00:00:00

  • Molecular mechanisms characterizing cone photoresponses.

    abstract::In the vertebrate retina, rods mediate twilight vision and cones mediate daylight vision. Their photoresponse characteristics are different. The light-sensitivity of a cone is 10(2)-10(3) times lower than that of a rod. In addition, the photoresponse time course is much faster in cones. The mechanism characterizing co...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Tachibanaki S,Shimauchi-Matsukawa Y,Arinobu D,Kawamura S

    更新日期:2007-01-01 00:00:00

  • Deactivation of singlet molecular oxygen by organo-selenium compounds exhibiting glutathione peroxidase activity and by sulfur-containing homologs.

    abstract::The bimolecular rate constants (k) of quenching of molecular singlet oxygen 1O2 (1 delta g) by organo-selenium compounds exhibiting glutathione peroxidase activity and by sulfur analogs have been determined by time resolved phosphorescence detection of 1O2 in CD3OD and C6D6, with no solvent effect. The rate constants ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Scurlock R,Rougée M,Bensasson RV,Evers M,Dereu N

    更新日期:1991-11-01 00:00:00

  • Comparison of nonmetal and metal hydrophilic photosensitizer, ATX-S10 (Na) and ATN-2, binding with human serum proteins using spectrophotometry.

    abstract::Intermolecular interactions of human serum proteins with a hydrophilic nonmetalloporphyrin, 13,17-bis(1-carboxypropionyl)carbomoylethyl-8-ethenyl-2-hydroxy-3-hydroxyiminoethylidene-2,7,12,18-tetramethylporphyrin sodium salt (ATX-S10 (Na)), or a hydrophilic gallium-metalloporphyrin, diethylenetriamine pentaacetic acid ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Yamaguchi M,Tanabe S,Nakajima S,Takemura T,Ogita K,Kuwayama H,Sakata I,Miyaki S,Suzuki K,Namiki H,Uzuka Y,Sarashina T

    更新日期:2004-09-01 00:00:00

  • Protective Effect of BLED-exposed Conditioned Media on Cell Injury.

    abstract::Previous studies have reported that 450 nm blue light emitting diode (BLED) induces apoptosis through a mitochondria-mediated pathway in cancer cells and reduces the early stage tumor growth. This study was performed to determine the effects of BLED-irradiated cell metabolites on cell injury. Our results showed that c...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Oh PS,Kim EM,Kim M,Kim IS,Han YH,Lim S,Sohn MH,Ko MH,Jeong HJ

    更新日期:2018-05-01 00:00:00

  • Dynamics change of phoborhodopsin and transducer by activation: study using D75N mutant of the receptor by site-directed solid-state 13C NMR.

    abstract::Pharaonis phoborhodopsin (ppR or sensory rhodopsin II) is a negative phototaxis receptor of Natronomonas pharaonis, and forms a complex, which transmits the photosignal into cytoplasm, with its cognate transducer (pHtrII). We examined a possible local dynamics change of ppR and its D75N mutant complexed with pHtrII, u...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kawamura I,Yoshida H,Ikeda Y,Yamaguchi S,Tuzi S,Saitô H,Kamo N,Naito A

    更新日期:2008-07-01 00:00:00

  • Peculiar properties of photoinduced hydroxylaminolysis in different bacteriorhodopsin-based media using O-substituted hydroxylamines.

    abstract::The process of photoinduced hydroxylaminolysis has been re-examined in different bacteriorhodopsin (BR)-based media using O-substituted hydroxylamines, in particular, O-(4-nitrobenzyl) hydroxylamine hydrochloride (NBHA), O-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine hydrochloride (FBHA) and O-(t-butyl) hydroxylamine h...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Dyukova TV,Druzhko AB

    更新日期:2010-11-01 00:00:00

  • Photoinduced degradation of the herbicide clomazone model reactions for natural and technical systems.

    abstract::The photodegradation of the herbicide clomazone in the presence of S(2)O(8) (2-) or of humic substances of different origin was investigated. A value of (9.4 +/- 0.4) x 10(8) m(-1) s(-1) was measured for the bimolecular rate constant for the reaction of sulfate radicals with clomazone in flash-photolysis experiments. ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: David Gara PM,Bosio GN,Arce VB,Poulsen L,Ogilby PR,Giudici R,Gonzalez MC,Mártire DO

    更新日期:2009-05-01 00:00:00

  • Luciferin-Regenerating Enzyme Crystal Structure Is Solved but its Function Is Still Unclear.

    abstract::Contribution of luciferin-regenerating enzyme (LRE) for in vitro recycling of D-luciferin has been reported. According to crystal structure of LRE, it is a beta-propeller protein which is a type of all β-protein architecture. In this overview, reinvestigation of the luciferase-based LRE assays and its function is repo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Hosseinkhani S,Emamgholi Zadeh E,Sahebazzamani F,Ataei F,Hemmati R

    更新日期:2017-03-01 00:00:00

  • The use of solar radiation by the photosynthetic bacterium, Rhodopseudomonas palustris: model simulation of conditions found in a shallow pond or a flatbed reactor.

    abstract::Photosynthetic bacteria are attractive for biotechnology because they produce no oxygen and so H2 -production is not inhibited by oxygen as occurs in oxygenic photoorganisms. Rhodopseudomonas palustris and Afifella marina containing BChl a can use irradiances from violet near-UV (VNUV) to orange (350-650 nm) light and...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Ritchie RJ

    更新日期:2013-09-01 00:00:00

  • Photosensitized reactions of poly(U) with tris(2,2'-bipyridyl)ruthenium(II) and peroxydisulfate.

    abstract::The reactions of polyuridylic acid [poly(U)] with Ru(bpy)3(3+) [Ru(III)] and SO4.-, following UV and visible light irradiation of Ru(bpy)3(2+) [Ru(II)] in the presence of S2O8(2-), were studied in an argon-saturated aqueous solution using time-resolved absorption and conductivity methods. The kinetics of the Ru(III) c...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Tossi AB,Görner H,Schulte-Frohlinde D

    更新日期:1989-11-01 00:00:00

  • Ultraviolet germicidal irradiation: future directions for air disinfection and building applications.

    abstract::Ultraviolet germicidal irradiation (UVGI) for air disinfection applications has relied on low-pressure mercury vapor lamps for decades. New design requirements have generated the need for alternatives in some uses. This study describes the current state of UVGI technology and describes future directions for technology...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Miller SL,Linnes J,Luongo J

    更新日期:2013-07-01 00:00:00

  • Analysis of the ethidium bromide bound to DNA by photoacoustic and FTIR spectroscopy.

    abstract::Under physiological conditions B-form DNA is an exceedingly stable structure. However, experimental evidences obtained through nuclear magnetic resonance and fluorescence anisotropy suggest that the structure of the double helix fluctuates substantially. We describe photoacoustic phase modulation frequency measurement...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Bugs MR,Cornélio ML

    更新日期:2001-10-01 00:00:00

  • Photodecomposition of vitamin A and photobiological implications for the skin.

    abstract::Vitamin A (retinol), an essential human nutrient, plays an important role in cellular differentiation, regulation of epidermal cell growth and normal cell maintenance. In addition to these physiological roles, vitamin A has a rich photochemistry. Photoisomerization of vitamin A, involved in signal transduction for vis...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Fu PP,Xia Q,Yin JJ,Cherng SH,Yan J,Mei N,Chen T,Boudreau MD,Howard PC,Wamer WG

    更新日期:2007-03-01 00:00:00

  • Enhancement of palladium-porphyrin room temperature phosphorescence by alkaline earth metal in deoxycholate aggregates solution.

    abstract::Room temperature phosphorescence (RTP) of three palladium (Pd)-phorphyrins in air-saturated solution of sodium deoxycholate (NaDC) aggregates was measured. RTP of Pd-meso-tetrakis (4-carboxyphenyl) porphyrin (Pd-TCPP) was obviously enhanced in NaDC-aggregates mediated by alkaline earth metal (AEM). Under the same expe...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Wang YT,Wang XW,Zhang Y

    更新日期:2011-07-01 00:00:00

  • Implication of ultraviolet light in the etiology of uveal melanoma: A review.

    abstract::Uveal melanoma is the most frequent intraocular cancer and the second most common form of melanoma. It metastasizes in half of the patients and the prognostic is poor. Although ultraviolet (UV) radiation is a proven risk factor for skin melanoma, the role of UV light in the etiology of uveal melanoma is still contradi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Mallet JD,Gendron SP,Drigeard Desgarnier MC,Rochette PJ

    更新日期:2014-01-01 00:00:00

  • Effect of oxygen on photoautotrophic and heterotrophic growth of Chlamydomonas reinhardtii in an anoxic atmosphere.

    abstract::Photoautotrophic growth of Chlamydomonas reinhardtii was shown to be independent of the presence of atmospheric oxygen. Under constant light and photoautotrophic conditions, C. reinhardtii grew equally well in either air or 367 PPM CO2-in-He. During 12-h light-dark cycles, the cells in air grew substantially faster th...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Graves DA,Spradlin GM,Greenbaum E

    更新日期:1990-09-01 00:00:00

  • Potential in vivo UVC disinfection of catheter lumens: estimation of the doses received by the blood flow outside the catheter tip hole.

    abstract::We have demonstrated that it is possible to launch UVC LED light into bacterial contaminated polymer tubes/catheters and disinfect the intraluminal space of these tubes. This can be achieved by UVC treatment of the catheters on a regular basis. Catheters are in the distal end equipped with an exit hole for administrat...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Bak J,Jørgensen TM,Helfmann J,Gravemann U,Vorontsova I

    更新日期:2011-03-01 00:00:00

  • Dye-sensitized destabilization of liposomes bearing photooxidizable lipid head groups.

    abstract::Liposomes were prepared from mixtures of dipalmitoyl-L-alpha-phosphatidylcholine and up to 40% mol:mol of N-stearoyl-L-histidine (NSH) in the presence of the hydrophobic sensitizer DHE. In the dark such liposomes are stable and retain entrapped salts. On photolysis with visible light, liposomes leak trapped ions at NS...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Chowdhary RK,Green CA,Morgan CG

    更新日期:1993-09-01 00:00:00

  • Effect of N-acetylcysteine on UVB-induced apoptosis and DNA repair in human and mouse keratinocytes.

    abstract::The incidence of skin cancer is increasing rapidly, particularly in the Caucasian population. Epidemiological and experimental studies demonstrated that ultraviolet radiation (UVR) is the primary cause for the increasing incidence of skin cancer. It is well known that UV irradiation induces DNA damage. If the damage i...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Bush JA,Ho VC,Mitchell DL,Tron VA,Li G

    更新日期:1999-09-01 00:00:00

  • Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers.

    abstract::The photostability of drugs administered topically on unprotected skin is a complex phenomenon that could be connected with the loss of activity or, rather rarely, the occurrence of toxic degradation products. In this study, an in-depth investigation of the photostability of terbinafine, in both solutions and formulat...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kryczyk-Poprawa A,Żmudzki P,Koczurkiewicz P,Pękala E,Hubicka U

    更新日期:2019-07-01 00:00:00

  • Daily duration of vitamin D synthesis in human skin with relation to latitude, total ozone, altitude, ground cover, aerosols and cloud thickness.

    abstract::Vitamin D production in human skin occurs only when incident UV radiation exceeds a certain threshold. From simulations of UV irradiances worldwide and throughout the year, we have studied the dependency of the extent and duration of cutaneous vitamin D production in terms of latitude, time, total ozone, clouds, aeros...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Engelsen O,Brustad M,Aksnes L,Lund E

    更新日期:2005-11-01 00:00:00