当前位置： SCI文献检索 > PHOTOCHEMISTRY AND PHOTOBIOLOGY期刊下所有文献 > Comparison of methylene blue and methylene violet for photoinactivation of intracellular and extracellular virus in red cell suspensions.

Comparison of methylene blue and methylene violet for photoinactivation of intracellular and extracellular virus in red cell suspensions.

Abstract：

:Previous studies with methylene blue (MB) in red cell suspensions have demonstrated that extracellular, but not intracellular, virus can be readily photoinactivated. To test if the resistance of intracellular virus to inactivation is related to the permanent positive charge of the phenothiazine, a series of uncharged phenothiazine dyes, methylene violet (MV), monodemethylated MV and didemethylated MV, were studied. Values of the sensitivity of intracellular relative to extracellular vesicular stomatitis virus (VSV) inactivation for the three dyes (D10 extracellular/D10 intracellular) in buffer were 1.0, 0.60 and 0.33, respectively. In contrast, intracellular virus was resistant to inactivation with MB, with a D10 extracellular/D10 intracellular of 0.05 in buffer. Because virucidal activity of MV was inhibited by the presence of plasma, the red cells (30% hematocrit) were repeatedly washed prior to photoinactivation and storage. Under conditions where MB and MV inactivated approximately 5 log10 of extracellular VSV, intracellular VSV was inactivated by more than 4 log10 with MV compared to 0.88 log10 with MB. These phototreatment conditions did not significantly affect red cell morphology, extracellular pH, ATP or 2,3-diphosphoglycerol levels during 42 days of 1-6 degrees C storage. There was enhanced potassium efflux and hemolysis over values obtained from untreated control; the extent of change from controls was comparable for each phototreatment. These results indicate that the uncharged phenothiazine dye, MV, can inactivate both intracellular and extracellular virus yet exhibit similar in vitro red cell storage properties as MB phototreatment.

journal_name

Photochem Photobiol

journal_title

Photochemistry and photobiology

authors

Skripchenko A,Robinette D,Wagner SJ

doi

10.1111/j.1751-1097.1997.tb08588.x

subject

Has Abstract

pub_date

1997-03-01 00:00:00

pages

451-5

issue

3

eissn

0031-8655

issn

1751-1097

journal_volume

65

pub_type

杂志文章

相关文献

PHOTOCHEMISTRY AND PHOTOBIOLOGY文献大全
  • Photoreceptor cell types in the retina of various vertebrate species: immunocytochemistry with antibodies against rhodopsin and iodopsin.

    abstract：:Types of photoreceptor cells in the retinas of 36 species of vertebrates (5 classes, 14 orders) were investigated immunocytochemically with monoclonal antibodies against chicken iodopsin (Io-mAb) and antiserum against bovine rhodopsin (Rh-As). In mammals, Rh-As labeled the outer segments of some photoreceptor cells in...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1992.tb09740.x

    authors： Kawata A,Oishi T,Fukada Y,Shichida Y,Yoshizawa T

    更新日期：1992-12-01 00:00:00

  • Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint.

    abstract：:Nucleotide excision repair and the ATR-mediated DNA damage checkpoint are two critical cellular responses to the genotoxic stress induced by ultraviolet (UV) light and are important for cancer prevention. In vivo genetic data indicate that these global responses are coupled. Aziz Sancar et al. developed an in vitro co...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章,评审

    doi：10.1111/php.12667

    authors： Lindsey-Boltz LA

    更新日期：2017-01-01 00:00:00

  • Spectroscopic properties of fluorescein and rhodamine dyes attached to DNA.

    abstract：:We report the spectroscopic properties of fluorescein, x-rhodamine, tetramethyl-rhodamine, attached to single strand, duplex DNA, and to the digestion products by DNAse I. The properties reported include: molar absorptivity, quantum yield, absorbance and fluorescence spectra, fluorescence lifetime, intrinsic lifetime ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.2009.00663.x

    authors： Delgadillo RF,Parkhurst LJ

    更新日期：2010-03-01 00:00:00

  • Photoenolization of o-Methylvalerophenone Ester Derivative.

    abstract：:Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12590

    authors： Das A,Lao EA,Gudmundsdottir AD

    更新日期：2016-05-01 00:00:00

  • The quenching of CdSe quantum dots photoluminescence by gold nanoparticles in solution.

    abstract：:The photoluminescence (PL) of CdSe quantum dots (QD) in aqueous media has been studied in the presence of gold nanoparticles (NP) with different shapes. The steady state PL intensity of CdSe QD (1.5-2 nm in size) is quenched in the presence of gold NP. Picosecond bleach recovery and nanosecond time-resolved luminescen...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/0031-8655(2002)075<0591:tqocqd>2.0.co;2

    authors： Nikoobakht B,Burda C,Braun M,Hun M,El-Sayed MA

    更新日期：2002-06-01 00:00:00

  • Iodouracil as a personal dosimeter for solar UVB.

    abstract：:A solution of iodouracil (0.2 mg/mL) and KI (0.1 M) in 0.23 M borate buffer (pH 7) forms triiodide upon exposure to UVB. In the presence of thyodene, the blue starch-iodine complex is formed, the intensity of which is proportional to the amount of UVB exposure. Studies were conducted using either a sunlamp or solar ir...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：

    authors： Rahn R,Lee MA

    更新日期：1998-08-01 00:00:00

  • The Photolyase/Cryptochrome Family of Proteins as DNA Repair Enzymes and Transcriptional Repressors.

    abstract：:Light is a very important environmental factor that governs many cellular responses in organisms. As a consequence, organisms possess different kinds of light-sensing photoreceptors to regulate their physiological variables and adapt to a given habitat. The cryptochrome/photolyase family (CPF) includes photoreceptors ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章,评审

    doi：10.1111/php.12669

    authors： Kavakli IH,Baris I,Tardu M,Gül Ş,Öner H,Çal S,Bulut S,Yarparvar D,Berkel Ç,Ustaoğlu P,Aydın C

    更新日期：2017-01-01 00:00:00

  • A multistate model for the fluorescence response of R-phycoerythrin.

    abstract：:Although strong fluorescence makes the R-phycoerythrin (R-PE) proteins increasingly useful in biological and clinical assays, they are subject to nonlinear effects including transitions to collective dark states and photodegradation, which complicate quantitative applications. We report measurements of R-PE fluorescen...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/2005-05-26-RA-544

    authors： Gaigalas A,Gallagher T,Cole KD,Singh T,Wang L,Zhang YZ

    更新日期：2006-05-01 00:00:00

  • The use of solar radiation by the photosynthetic bacterium, Rhodopseudomonas palustris: model simulation of conditions found in a shallow pond or a flatbed reactor.

    abstract：:Photosynthetic bacteria are attractive for biotechnology because they produce no oxygen and so H2 -production is not inhibited by oxygen as occurs in oxygenic photoorganisms. Rhodopseudomonas palustris and Afifella marina containing BChl a can use irradiances from violet near-UV (VNUV) to orange (350-650 nm) light and...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12124

    authors： Ritchie RJ

    更新日期：2013-09-01 00:00:00

  • Spectroscopic properties of potential sensitizers for new photodynamic therapy start mechanisms via two-step excited electronic states.

    abstract：:Three substituted tetraazaporphyrins, octa-(4-tert-butylphenyl)-tetrapyrazinoporphyrazine, tetra-(4-tert-butyl)phthalocyanine and tetra-(4-tert-butyl)phthalocyanatomagnesium(t4-PcMg), were spectroscopically checked in solutions and liposomes with respect to suitability as potential sensitizers of a possible new start ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1993.tb02320.x

    authors： Teuchner K,Pfarrherr A,Stiel H,Freyer W,Leupold D

    更新日期：1993-03-01 00:00:00

  • Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures.

    abstract：:In the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level. Moreover, cerco is efficiently...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.13257

    authors： Grigalavicius M,Mastrangelopoulou M,Arous D,Juzeniene A,Ménard M,Skarpen E,Berg K,Theodossiou TA

    更新日期：2020-05-01 00:00:00

  • Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: a Double-blind, Randomized Placebo-controlled Clinical Study.

    abstract：:Photoprotective formulations containing substances with antioxidant properties in combination have been used as a strategy for the improvement of photoaged skin conditions. However, there is a lack of studies evaluating the clinical efficacy of these substances in young women with signs of photoaging. Thus, the object...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.13390

    authors： Fossa Shirata MM,Maia Campos PMBG

    更新日期：2021-02-02 00:00:00

  • Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

    abstract：:Ultraviolet (UV) radiation is among the most prevalent environmental factors that influence human health and disease. Even 1 h of UV irradiation extensively damages the genome. To cope with resulting deleterious DNA lesions, cells activate a multitude of DNA damage response pathways, including DNA repair. Strikingly, ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.13245

    authors： Lee JW,Ratnakumar K,Hung KF,Rokunohe D,Kawasumi M

    更新日期：2020-05-01 00:00:00

  • Photochemical syn-anti isomerization reactions in N2-hydroxyisocytosines--an experimental matrix isolation and theoretical study.

    abstract：:N2-hydroxyisocytosine and 1-methyl-N2-hydroxyisocytosine were studied using a matrix isolation technique combined with infrared absorption spectroscopy. For N2-hydroxyisocytosine isolated in an Ar matrix (at 10 K), two imino-oxo isomers, one with the hydroxyimino =N-OH group directed toward the N1-H group (the form ca...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/0031-8655(2003)077<0243:psairi>2.0.co;2

    authors： Lapinski L,Nowak MJ,Kwiatkowski JS,Leszczynski J

    更新日期：2003-03-01 00:00:00

  • In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.

    abstract：:Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectanc...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1991.tb08470.x

    authors： Marchesini R,Brambilla M,Clemente C,Maniezzo M,Sichirollo AE,Testori A,Venturoli DR,Cascinelli N

    更新日期：1991-01-01 00:00:00

  • Fusion-fission transport of probes and quenchers in microdomains of an amphiphilic ionene polyelectrolyte.

    abstract：:In aqueous solution, amphiphilic ionenes such as the [3,22]-ionene spontaneously adopt globular conformations and form microdomains that are highly micelle-like, i.e. are capable of solubilizing organic molecules, binding and exchanging counterions and accelerating or inhibiting the rates of bimolecular reactions. Tim...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/2006-09-09-RA-1036

    authors： Tcacenco CM,Quina FH

    更新日期：2007-05-01 00:00:00

  • Subcellular localization of hematoporphyrin derivative in bladder tumor cells in culture.

    abstract：:Mitochondria have been implicated as a primary subcellular site of porphyrin localization and photodestruction. However, other organelles including the cell membrane, lysosomes and nucleus have been shown to be damaged by hematoporphyrin derivative (HpD) photosensitized destruction as well. In this study we attempted ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1990.tb01736.x

    authors： Shulok JR,Wade MH,Lin CW

    更新日期：1990-04-01 00:00:00

  • Resolution of the individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin.

    abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1994.tb09664.x

    authors： Sirangelo I,Irace G,Bismuto E

    更新日期：1994-06-01 00:00:00

  • Identification of a transforming ras oncogene in an ultraviolet radiation-induced corneal tumor of Monodelphis domestica.

    abstract：:Chronic exposure of the gray, short-tailed oppossum, Monodelphis domestica to ultraviolet radiation (UVR) induces mesenchymal tumors of the cornea. High molecular weight DNA samples from 6 UVR-induced corneal tumors were assayed for their ability to transform NIH 3T3 cells to tumorigenicity. NIH 3T3 cells transfected ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1992.tb04256.x

    authors： Sabourin CL,Freeman AG,Kusewitt DF,Ley RD

    更新日期：1992-03-01 00:00:00

  • Species-specific responses to combined thermal-irradiance stress in microalgae--"each is to its own".

    abstract：:This article is a highlight of the study by Stamenkovic and Hanelt in this issue of Photochemistry and Photobiology describing the high-irradiance photophysiology of several strains of freshwater chlorophyte microalgal genus, Cosmarium. These strains exhibit distinct differences in how combined thermal- high irradianc...

    journal_title：Photochemistry and photobiology

    pub_type： 评论,杂志文章

    doi：10.1111/php.12081

    authors： Neale P

    更新日期：2013-07-01 00:00:00

  • Effects of low-power laser irradiation on cell locomotion in protozoa.

    abstract：:Low-power lasers are commonly used in human medicine for treatment of various pathological conditions, but mechanisms of their healing effects are still poorly understood. The results of this study provide information related to these effects at the cellular level. Two different protozoan species, Euglena gracilis and...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/0031-8655(2004)080<0531:EOLLIO>2.0.CO;2

    authors： Koutna M,Janisch R,Unucka M,Svobodnik A,Mornstein V

    更新日期：2004-11-01 00:00:00

  • Baicalin Protects Keratinocytes from Toll-like Receptor-4 Mediated DNA Damage and Inflammation Following Ultraviolet Irradiation.

    abstract：:UVB radiation contributes to both direct and indirect damage to the skin including the generation of free radicals and reactive oxygen species (ROS), inflammatory responses, immunosuppression and gene mutations, which can ultimately lead to photocarcinogenesis. A plant-derived flavonoid, baicalin, has been shown to ha...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12505

    authors： Min W,Ahmad I,Chang ME,Burns EM,Qian Q,Yusuf N

    更新日期：2015-11-01 00:00:00

  • Effect of Light Environment on Growth and Phenylpropanoids of Yarrow (Achillea collina cv. SPAK) Grown in the Alps.

    abstract：:A 2-year field study on the effect of different light environments, obtained by using cladding materials (polyethylene films and shade net) able to cut off specific regions of the photosynthetically active radiation and ultraviolet wavebands, on the growth and phenylpropanoids content of Achillea collina grown in the ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12150

    authors： Giorgi A,Manzo A,Vagge I,Panseri S

    更新日期：2014-01-01 00:00:00

  • Electron transfer quenching of the rose bengal triplet state.

    abstract：:The potential for electron transfer quenching of rose bengal triplet (3RB2-) to compete with energy transfer quenching by oxygen was evaluated. Rate constants for oxidative and reductive quenching were measured in buffered aqueous solution, acetonitrile and in small unilamellar liposomes using laser flash photolysis. ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1997.tb03133.x

    authors： Lambert CR,Kochevar IE

    更新日期：1997-07-01 00:00:00

  • Chlorin-bacteriochlorin energy-transfer dyads as prototypes for near-infrared molecular imaging probes: controlling charge-transfer and fluorescence properties in polar media.

    abstract：:The photophysical properties of two energy-transfer dyads that are potential candidates for near-infrared (NIR) imaging probes are investigated as a function of solvent polarity. The dyads (FbC-FbB and ZnC-FbB) contain either a free base (Fb) or zinc (Zn) chlorin (C) as the energy donor and a free base bacteriochlorin...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.2008.00532.x

    authors： Kee HL,Diers JR,Ptaszek M,Muthiah C,Fan D,Lindsey JS,Bocian DF,Holten D

    更新日期：2009-07-01 00:00:00

  • Characterization of 3-Acetyl Chlorophyll a and 3-Acetyl Protochlorophyll a Accommodated in the B800 Binding Sites of Photosynthetic Light-Harvesting Complex 2 in the Purple Photosynthetic Bacterium Rhodoblastus acidophilus.

    abstract：:We present the detailed characterization on the reconstitution of two cyclic tetrapyrrole pigments that have the same substituents but differ in the degree of hydrogenation in the macrocycles from bacteriochlorophyll (BChl) a (7,8,17,18-tetrahydroporphyrin) into the binding sites of B800 BChl a in light-harvesting com...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12919

    authors： Saga Y,Miyagi K

    更新日期：2018-07-01 00:00:00

  • Enhancement of fluoresceinyl cypridina luciferin analog chemiluminescence by human serum albumin for singlet oxygen detection.

    abstract：:Fluoresceinyl cypridina luciferin analog (FCLA) is a chemiluminescence (CL) probe for detecting reactive oxygen species (ROS). Its efficiency for detecting singlet oxygen (1O2) can be significantly enhanced in the presence of human serum albumin (HSA). This phenomenon may apply to important applications for both resea...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/2005-12-02-ra-744

    authors： Zhou J,Xing D,Chen Q

    更新日期：2006-07-01 00:00:00

  • Mechanism of lipid peroxidation photosensitized by tiaprofenic acid: product studies using linoleic acid and 1,4-cyclohexadienes as model substrates.

    abstract：:A careful study of the linoleic acid hydroperoxide (LOOH) profile obtained upon peroxidation of linoleic acid (LA) photosensitized by tiaprofenic acid (TPA) and analogous ketones has been undertaken to distinguish between type-I and type-II photoperoxidation mechanisms. 1,4-Cyclohexadiene and 1,2-dimethylcyclohexa-2,5...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1562/0031-8655(2001)073<0359:molppb>2.0.co;2

    authors： Samadi A,Martínez LA,Miranda MA,Morera IM

    更新日期：2001-04-01 00:00:00

  • Solvothermal Synthesis of Cs0.33 WO3 /LDHs Composite as a Novel Visible-Light-Driven Photocatalyst.

    abstract：:A novel Cs0.33 WO3 /LDHs (CWLDH) composite was synthesized by simple two steps solvothermal method and first investigated as the photocatalyst for tetracycline (TC) and Congo red (CR) degradation under visible light irradiation. The CWLDH heterostructures catalysts were characterized by XRD, UV-Vis, SEM, XPS and BET. ...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/php.12838

    authors： Zhang D,Ji T,Yu J,Jiang X,Jiao F

    更新日期：2018-03-01 00:00:00

  • Synthesis of positively charged phthalocyanines and their activity in the photodynamic therapy of cancer cells.

    abstract：:Positively charged zinc containing or metal free phthalocyanines 6a-c and 7a-c were prepared via a three step procedure starting from 4-nitrophthalonitrile. The phthalocyanines contain alkyl chains of different length in order to influence the hydrophilic vs lipophilic character of the compounds. The partition between...

    journal_title：Photochemistry and photobiology

    pub_type： 杂志文章

    doi：10.1111/j.1751-1097.1990.tb01721.x

    authors： Wöhrle D,Iskander N,Graschew G,Sinn H,Friedrich EA,Maier-Borst W,Stern J,Schlag P

    更新日期：1990-03-01 00:00:00