Abstract:
:Light is a very important environmental factor that governs many cellular responses in organisms. As a consequence, organisms possess different kinds of light-sensing photoreceptors to regulate their physiological variables and adapt to a given habitat. The cryptochrome/photolyase family (CPF) includes photoreceptors that perform different functions in different organisms. Photolyases repair ultraviolet-induced DNA damage by a process known as photoreactivation using photons absorbed from the blue end of the light spectrum. On the other hand, cryptochromes act as blue light circadian photoreceptors in plants and Drosophila to regulate growth and development. In mammals, cryptochromes have light-independent functions and are very important transcriptional regulators that act at the molecular level as negative transcriptional regulators of the circadian clock. In this review, we highlight current knowledge concerning the structural and functional relationships of CPF members.
journal_name
Photochem Photobioljournal_title
Photochemistry and photobiologyauthors
Kavakli IH,Baris I,Tardu M,Gül Ş,Öner H,Çal S,Bulut S,Yarparvar D,Berkel Ç,Ustaoğlu P,Aydın Cdoi
10.1111/php.12669subject
Has Abstractpub_date
2017-01-01 00:00:00pages
93-103issue
1eissn
0031-8655issn
1751-1097journal_volume
93pub_type
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