Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

abstract：:Identification of natural products capable of affording protection against UVB radiation-induced inflammatory responses and generation of oxidative stress may have important human health implications. The UVB exposure-induced skin injury and oxidative stress has been associated with a variety of skin disease condition...

journal_title：Photochemistry and photobiology

authors： Katiyar SK,Matsui MS,Elmets CA,Mukhtar H

更新日期：1999-02-01 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygote of the brown alga, Silvetia compressa. This effect is mediated by an increase in the intracellular concentration of guanosine 3', 5'-cyclic monophosphate. In this study we show the identification of a rhodopsin-like protein, by means of an...

journal_title：Photochemistry and photobiology

authors： Gualtieri P,Robinson KR

更新日期：2002-01-01 00:00:00

abstract：:Studies have reported the association of human leukocyte antigen (HLA) genes with susceptibility to develop actinic prurigo (AP) in Caucasians, but there were no studies in Asian populations, including the Chinese. Our study was performed to determine if AP is associated with susceptibility or protective HLA alleles o...

journal_title：Photochemistry and photobiology

authors： Chen Q,Shen M,Heng YK,Theng TSC,Tey HL,Ren EC,Chong WS

更新日期：2016-03-01 00:00:00

abstract：:Bacteriochlorophyll (BChl) e was coassembled with BChl c in Triton X-100 micelles in aqueous solutions. The Qy absorption bands of the coaggregates were positioned between those of aggregates consisting solely of BChl c or e. The electronic absorption spectra of the coaggregates could not be reproduced by linear combi...

journal_title：Photochemistry and photobiology

authors： Saga Y,Saiki T,Takahashi N,Shibata Y,Tamiaki H

更新日期：2014-05-01 00:00:00

abstract：:Spatio-temporal patterns in sun exposure underlie variations in skin cancer incidence and vitamin D deficiency, indicate effectiveness of sun protection programs and provide insights into future health risks. From 558 adults across four regions of Australia (Brisbane (27°S), Newcastle (33°S), Geelong and the Western D...

journal_title：Photochemistry and photobiology

authors： Lucas RM,Valery P,van der Mei I,Dwyer T,Pender MP,Taylor B,Ponsonby AL,Ausimmune Investigator Group.

更新日期：2013-05-01 00:00:00

abstract：:Albino hairless mice (Skh: HR-1) exposed chronically to sub-erythemal doses of UV radiation display physical, visible and histological alterations. Using narrow bandwidth radiation covering the UV radiation spectrum from 280-380 nm, the wavelength dependence of these alterations was determined. The wavelength dependen...

journal_title：Photochemistry and photobiology

authors： Bissett DL,Hannon DP,Orr TV

更新日期：1989-12-01 00:00:00

abstract：:The cellular uptake of Photofrin II (PII) was studied using fluorescence imaging and chemical extraction. The influence of serum and low density lipoproteins (LDL) was examined under a variety of experimental conditions employing cultured human cells of different origins as well as a subcutaneously SMT-F tumor implant...

journal_title：Photochemistry and photobiology

authors： Korbelik M,Hung J,Lam S,Palcic B

更新日期：1990-02-01 00:00:00

abstract：:Molecular beacons (MB) are becoming more common as sequence-selective detectors of nucleic acids. Although they can easily detect single-base mismatches, they have never been used to directly detect DNA or RNA damage. To measure the degree of ultraviolet (UV) light damage in oligonucleotides, we report a novel MB appr...

journal_title：Photochemistry and photobiology

authors： Yarasi S,McConachie C,Loppnow GR

更新日期：2005-03-01 00:00:00

abstract：:UV-induced toxicity is characterized by marked oxidative stress, accompanied by the depletion of key cellular antioxidants, particularly glutathione (GSH). Replenishing cellular GSH may represent a means of counteracting UV-induced toxicity: however, treatment with free GSH is not therapeutically effective due to its ...

journal_title：Photochemistry and photobiology

authors： Wright D,Zampagni M,Evangelisti E,Conti S,D'Adamio G,Goti A,Becatti M,Fiorillo C,Taddei N,Cecchi C,Liguri G

更新日期：2013-03-01 00:00:00

abstract：:Photodetection (PD) and photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PPIX) accumulation are approaches to detect and treat dysplasia and early cancer in the gastrointestinal tract and in the urinary bladder. Because ALA-induced PPIX production is limited, we synthesized ALA es...

journal_title：Photochemistry and photobiology

authors： Brunner H,Hausmann F,Knuechel R

更新日期：2003-11-01 00:00:00

abstract：:Antibodies and antigen binding fragments thereof were photochemically immobilized on surface-modified silicon chips of 5 x 5 mm size. Silicon surface-grafted diazirines and benzophenones formed covalent bonds with the immunoreagents on light activation. Photolithographic immobilization of monoclonal antibodies in aque...

journal_title：Photochemistry and photobiology

authors： Sundarababu G,Gao H,Sigrist H

更新日期：1995-06-01 00:00:00

abstract：:Neutral filter elution at pH 7.2 and 9.6 was used to measure the induction of DNA lesions in human P3 teratocarcinoma cells by monochromatic 254-, 270-, 313-, 334-, 365-, and 405-nm radiation and by 60 gamma rays. In this assay DNA double-strand breaks (dsb) increase the rate of elution of DNA from cell lysates on a f...

journal_title：Photochemistry and photobiology

authors： Peak JG,Peak MJ

更新日期：1990-08-01 00:00:00

abstract：:UV radiation (UVR) is a significant ecological factor in the marine environment that can have important effects on planktonic organisms and dissolved organic matter (DOM). The penetration of UVR into the water column is likely to change in the near future due to interactions between global warming and ozone depletion....

journal_title：Photochemistry and photobiology

authors： Tedetti M,Sempéré R

更新日期：2006-03-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:A spectral resolution procedure was used to resolve the absorption, excitation and emission spectra of the fluorescein monoanion in a number of solvent-water mixtures. This permitted an analysis of the effect of the solvent environment on the spectral properties of the monoanion and on the lactone/monoanion/dianion tr...

journal_title：Photochemistry and photobiology

authors： Klonis N,Sawyer WH

更新日期：2000-08-01 00:00:00

abstract：:This study compares the abilities of the glutathione (GSH) and thioredoxin (Trx) antioxidant systems in defending cultured human lens epithelial cells (LECs) against UVA light. Levels of GSH were depleted with either L-buthionine-(S,R)-sulfoximine (BSO) or 1-chloro-2,4-dinitrobenzene (CDNB). CDNB treatment also inhibi...

journal_title：Photochemistry and photobiology

authors： Padgaonkar VA,Leverenz VR,Bhat AV,Pelliccia SE,Giblin FJ

更新日期：2015-03-01 00:00:00

abstract：:Demetalation kinetics of bacteriochlorophylls (BChls) c, d and e from green sulfur photosynthetic bacteria were studied under weakly acidic conditions. Demetalation rate constants of BChl e possessing a formyl group at the 7-position were significantly smaller than those of BChls c and d, which had a methyl group at t...

journal_title：Photochemistry and photobiology

authors： Hirai Y,Tamiaki H,Kashimura S,Saga Y

更新日期：2009-09-01 00:00:00

abstract：:A 24 h preculture of HT29-18 human colonic adenocarcinoma cells with the sterol synthesis inhibitor lovastatin at concentrations of 0.1-0.5 microM markedly increased the photocytotoxic effect of photofrin II delivered to cells by low density lipoproteins. Under the same conditions, LDL binding and photofrin II (PII) u...

journal_title：Photochemistry and photobiology

authors： Biade S,Mazière JC,Mora L,Santus R,Mazière C,Auclair M,Morlière P,Dubertret L

更新日期：1993-02-01 00:00:00

abstract：:Macroalgae distributed in intertidal zones experience a series of environmental changes, such as periodical desiccation associated with tidal cycles, increasing CO2 concentration and solar UVB (280-315 nm) irradiance in the context of climate change. We investigated how the economic red macroalga, Pyropia haitanensis,...

journal_title：Photochemistry and photobiology

authors： Xu J,Gao K

更新日期：2015-11-01 00:00:00

abstract：:Although ultraviolet-B (UV-B) radiation is potentially harmful, it is an important component of terrestrial radiation to which plants have been exposed since invading land. Since then, plants have evolved mechanisms to avoid and repair UV radiation damage; therefore, it is not surprising that photomorphogenic response...

journal_title：Photochemistry and photobiology

authors： Gitz DC,Liu-Gitz L

更新日期：2003-12-01 00:00:00

abstract：:As a new class of sequence-specific regulators of gene expression, the microRNAs (miRNA) form a regulatory network with growth factors and transcription factors participating in various biological processes. It is now being recognized that the various key processes involved in cancer induction are under the control of...

journal_title：Photochemistry and photobiology

authors： Syed DN,Lall RK,Mukhtar H

更新日期：2015-01-01 00:00:00

abstract：:The photodegradation of the herbicide clomazone in the presence of S(2)O(8) (2-) or of humic substances of different origin was investigated. A value of (9.4 +/- 0.4) x 10(8) m(-1) s(-1) was measured for the bimolecular rate constant for the reaction of sulfate radicals with clomazone in flash-photolysis experiments. ...

journal_title：Photochemistry and photobiology

authors： David Gara PM,Bosio GN,Arce VB,Poulsen L,Ogilby PR,Giudici R,Gonzalez MC,Mártire DO

更新日期：2009-05-01 00:00:00

abstract：:In studies of the biological effects of UV radiation, ozone depletion can be mimicked by performing the study under ambient conditions and adding radiation with UV-B lamps. We evaluated this methodology at three different locations along a latitudinal gradient: Rimouski (Canada), Ubatuba (Brazil) and Ushuaia (Argentin...

journal_title：Photochemistry and photobiology

authors： Díaz S,Camilión C,Escobar J,Deferrari G,Roy S,Lacoste K,Demers S,Belzile C,Ferreyra G,Gianesella S,Gosselin M,Nozais C,Pelletier E,Schloss I,Vernet M

更新日期：2006-07-01 00:00:00

abstract：:Carp (Cyprinus carpio) were repeatedly exposed to 0, 60, 120 and 240 mJ/cm2 ultraviolet B (UVB) radiation three times in 1 week (short-term exposure) or 12 times in 4 weeks (long-term exposure). The effect of UVB on the functioning of the carp immune system was studied on day 2 after the final irradiation. After short...

journal_title：Photochemistry and photobiology

authors： Markkula SE,Salo HM,Immonen AK,Jokinen EI

更新日期：2005-05-01 00:00:00

abstract：:Photodynamic therapy (PDT) using the second-generation photosensitizer phthalocyanine (Pc) 4 causes mitochondrial damage and induces apoptosis through the release of cytochrome c to the cytosol. Another protein of the mitochondrial intermembrane space, Smac/DIABLO (second mitochondria-derived activator of caspase/dire...

journal_title：Photochemistry and photobiology

authors： Usuda J,Chiu SM,Azizuddin K,Xue LY,Lam M,Nieminen AL,Oleinick NL

更新日期：2002-08-01 00:00:00

abstract：:Four chemical preservatives commonly used in ophthalmic solutions were tested for their toxic and mutagenic potential in mouse lymphoma cells with and without exposure of the cells to ultraviolet A (UVA) radiation. The preservatives tested were benzalkonium chloride (BAK), chlorhexidine, thimerosal and ethylenediamine...

journal_title：Photochemistry and photobiology

authors： Withrow TJ,Brown NT,Hitchins VM,Strickland AG

更新日期：1989-09-01 00:00:00

abstract：:A 2-year field study on the effect of different light environments, obtained by using cladding materials (polyethylene films and shade net) able to cut off specific regions of the photosynthetically active radiation and ultraviolet wavebands, on the growth and phenylpropanoids content of Achillea collina grown in the ...

journal_title：Photochemistry and photobiology

authors： Giorgi A,Manzo A,Vagge I,Panseri S

更新日期：2014-01-01 00:00:00

abstract：:The UV radiation environment on planetary surfaces and within atmospheres is of importance in a wide range of scientific disciplines. Solar UV radiation is a driving force of chemical and organic evolution and serves also as a constraint in biological evolution. In this work we modeled the transmission of present and ...

journal_title：Photochemistry and photobiology

authors： Rontó G,Bérces A,Lammer H,Cockell CS,Molina-Cuberos GJ,Patel MR,Selsis F

更新日期：2003-01-01 00:00:00

abstract：:A key challenge for microbiology is to understand how evolution has shaped the wiring of regulatory networks. This is amplified by the paucity of information of power-spectra of physicochemical stimuli to which microorganisms are exposed. Future studies of genome evolution, driven by altered stimulus regimes, will the...

journal_title：Photochemistry and photobiology

authors： van der Steen JB,Hellingwerf KJ

更新日期：2015-09-01 00:00:00

abstract：:Tetraarylporphyrins substituted with nitro groups at beta-pyrrolic positions are potential candidates for electron-accepting pigments in model systems for photosynthesis. The photophysics of 2-nitro-5,10,15,20-tetra-p-tolylporphyrin and its zinc analog have been studied in order to evaluate this potential. The ground ...

journal_title：Photochemistry and photobiology

authors： Gust D,Moore TA,Luttrull DK,Seely GR,Bittersmann E,Bensasson RV,Rougée M,Land EJ,De Schryver FC,Van der Auweraer M

更新日期：1990-04-01 00:00:00