Ultraviolet light induces double-strand breaks in DNA of cultured human P3 cells as measured by neutral filter elution.

abstract：:Eumelanin (brown/black melanin) and pheomelanin (red/yellow melanin) in human hair can be quantified using chemical methods or approximated using spectrophotometric methods. Chemical methods consume greater resources, making them less attractive for epidemiological studies. This investigation sought to identify the sp...

journal_title：Photochemistry and photobiology

authors： Shekar SN,Duffy DL,Frudakis T,Montgomery GW,James MR,Sturm RA,Martin NG

更新日期：2008-05-01 00:00:00

abstract：:Herbal extracts including asiatic acid (AA) have become popular candidates of anti-photoaging agents due to their anti-inflammatory and antioxidant properties and minimal side effect. Nevertheless, low bioavailability due to poor solubility limits their practical application. In this study, a highly bioavailable form ...

journal_title：Photochemistry and photobiology

authors： Huang J,Tu T,Wang W,Zhou G,Zhang W,Wu X,Liu W

更新日期：2020-01-01 00:00:00

abstract：:Previous studies have shown that natural killer (NK) cell activity was suppressed in volunteer subjects exposed to ultraviolet radiation (UVR) from solarium lamps. The present studies were carried out to determine the spectrum of UVR responsible for suppression of NK activity and to develop in vitro methods to analyze...

journal_title：Photochemistry and photobiology

authors： Hersey P,Magrath H,Wilkinson F

更新日期：1993-02-01 00:00:00

abstract：:Skin cancer is the most prevalent cancer, and its assessment remains a challenge for physicians. This study reports the application of an optical sensing method, elastic scattering spectroscopy (ESS), coupled with a classifier that was developed with machine learning, to assist in the discrimination of skin lesions th...

journal_title：Photochemistry and photobiology

authors： Rodriguez-Diaz E,Manolakos D,Christman H,Bonning MA,Geisse JK,A'Amar OM,Leffell DJ,Bigio IJ

更新日期：2019-11-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Aqueous solutions of KI were examined for use as chemical actinometers to measure 254 nm (germicidal) radiation. Irradiation results in electron ejection from iodide such that aqueous electrons and iodine atoms are formed. In the presence of N2O, an electron scavenger, recombination of these two reactive species is el...

journal_title：Photochemistry and photobiology

authors： Rahn RO

更新日期：1993-12-01 00:00:00

abstract：:Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is accomplished through careful avoidance of sun exposure and artificial ...

journal_title：Photochemistry and photobiology

authors： Klein RS,Werth VP,Dowdy JC,Sayre RM

更新日期：2009-07-01 00:00:00

abstract：:The size of excision repair patches corresponding to excision of (6-4) pyrimidine-pyrimidone photoproducts and (5-5, 6-6) cyclobutane dimers have been independently determined by using bromodeoxyuridine substitution and density increases in isopycnic gradients of small DNA fragments. The two classes of photoproducts w...

journal_title：Photochemistry and photobiology

authors： Cleaver JE,Jen J,Charles WC,Mitchell DL

更新日期：1991-09-01 00:00:00

abstract：:Lamprigera (Lampyridae) is a small genus with only 17 species distributing in Asian countries. Its larviform females and alate males can produce continuously strong yellow-green light at night. However, no luciferase gene was reported for this genus and its subfamily-level phylogenetic position still remains uncertain...

journal_title：Photochemistry and photobiology

authors： Liu GC,Zhang R,Hou QB,He JW,Dong ZW,Zhao RP,Wang W,Li XY

更新日期：2019-09-01 00:00:00

abstract：:The photoinduced covalent binding of the title compound to native and heat denatured DNA is described. The level of binding has been measured by UV (for DNA) and atomic absorption (for Rh) analysis. Quantum efficiencies of 6.4 x 10(-4) mol Rh per mol photons and 1.6 x 10(-3) mol Rh per mol photons have been determined...

journal_title：Photochemistry and photobiology

authors： Mahnken RE,Bina M,Deibel RM,Luebke K,Morrison H

更新日期：1989-04-01 00:00:00

abstract：:Assignment of the fluorescence spectrum of firefly luciferin in aqueous solutions was achieved by utilizing not only emission energies but also theoretical absorption spectra and relative concentrations as estimated by pKa values. Calculated Gibbs free energies were utilized to estimate pKa values. These pKa values we...

journal_title：Photochemistry and photobiology

authors： Hiyama M,Akiyama H,Yamada K,Koga N

更新日期：2014-01-01 00:00:00

abstract：:Contribution of luciferin-regenerating enzyme (LRE) for in vitro recycling of D-luciferin has been reported. According to crystal structure of LRE, it is a beta-propeller protein which is a type of all β-protein architecture. In this overview, reinvestigation of the luciferase-based LRE assays and its function is repo...

journal_title：Photochemistry and photobiology

authors： Hosseinkhani S,Emamgholi Zadeh E,Sahebazzamani F,Ataei F,Hemmati R

更新日期：2017-03-01 00:00:00

abstract：:The capacity of some linear and angular furocoumarins to induce DNA-protein cross-links by UVA (320-400 nm) irradiation has been evaluated in Chinese hamster ovary cells. Two linear furocoumarins, psoralen and 8-methoxypsoralen appeared to be capable of inducing DNA-protein cross-links to a noticeable extent. 4'-Methy...

journal_title：Photochemistry and photobiology

authors： Bordin F,Carlassare F,Busulini L,Baccichetti F

更新日期：1993-07-01 00:00:00

abstract：:Synovial sarcoma (SS) is one of common malignant soft-tissue tumors and is encountered most commonly in children and young adults. It frequently involves or invades major neurovascular structures and bones, and its local recurrence rate after simple resection has been reported to be as high as up to 80%. Because major...

journal_title：Photochemistry and photobiology

authors： Kusuzaki K,Murata H,Matsubara T,Miyazaki S,Shintani K,Seto M,Matsumine A,Hosoi H,Sugimoto T,Uchida A

更新日期：2005-05-01 00:00:00

abstract：:The fluoroquinolone (FQ) antibiotics photosensitize human skin to solar UV radiation and are reported to photosensitize tumor formation in mouse skin. As tumor initiation will not occur without genotoxic insult, we examined the potential of ciprofloxacin, lomefloxacin, fleroxacin, BAYy3118 (a recently developed monofl...

journal_title：Photochemistry and photobiology

authors： Reavy HJ,Traynor NJ,Gibbs NK

更新日期：1997-09-01 00:00:00

abstract：:Although allergic rhinitis is not life threatening, it significantly influences the quality of a patient's life. This study is intended to evaluate the safety and efficacy of phototherapy with low-level energy of a 650 nm laser irradiation system in perennial allergic rhinitis patients. This clinical trial was an open...

journal_title：Photochemistry and photobiology

authors： Lee HM,Park MS,Park IH,Lee SH,Lee SK,Kim KS,Choi H

更新日期：2013-05-01 00:00:00

abstract：:Work in the past 8 years, particularly in the past 1-2 years, has greatly expanded our understanding of the mechanisms by which ultraviolet irradiation stimulates melanogenesis in the skin. A direct effect of UV photons on DNA results in up-regulation of the gene for tyrosinase, the rate-limiting enzyme in melanin syn...

journal_title：Photochemistry and photobiology

authors： Gilchrest BA,Park HY,Eller MS,Yaar M

更新日期：1996-01-01 00:00:00

abstract：:UV-induced toxicity is characterized by marked oxidative stress, accompanied by the depletion of key cellular antioxidants, particularly glutathione (GSH). Replenishing cellular GSH may represent a means of counteracting UV-induced toxicity: however, treatment with free GSH is not therapeutically effective due to its ...

journal_title：Photochemistry and photobiology

authors： Wright D,Zampagni M,Evangelisti E,Conti S,D'Adamio G,Goti A,Becatti M,Fiorillo C,Taddei N,Cecchi C,Liguri G

更新日期：2013-03-01 00:00:00

abstract：:The biguanide metformin is widely used for the treatment of Type-II diabetes. Its antiproliferative and pro-apoptotic effects in various tumor cells suggest its potential candidacy for cancer chemoprevention. Herein, we report that metformin significantly inhibited human epidermoid A431 tumor xenograft growth in nu/nu...

journal_title：Photochemistry and photobiology

authors： Chaudhary SC,Kurundkar D,Elmets CA,Kopelovich L,Athar M

更新日期：2012-09-01 00:00:00

abstract：:The UV radiation environment on planetary surfaces and within atmospheres is of importance in a wide range of scientific disciplines. Solar UV radiation is a driving force of chemical and organic evolution and serves also as a constraint in biological evolution. In this work we modeled the transmission of present and ...

journal_title：Photochemistry and photobiology

authors： Rontó G,Bérces A,Lammer H,Cockell CS,Molina-Cuberos GJ,Patel MR,Selsis F

更新日期：2003-01-01 00:00:00

abstract：:Porous ZnS and ZnO nano-crystal films were fabricated via a three-step procedure. First, Zn(CH3 COO)2 /Silk Fibroin nanofiber mats were prepared by coaxial electrospinning. Second, Zn(CH3 COO)2 /Silk Fibroin mats were immersed in NaS solution to react with S2- to obtain ZnS/Silk Fibroin nanofiber mats. Finally, ZnO po...

journal_title：Photochemistry and photobiology

authors： Wang H,Liang L,Cheng X,Luo Y,Sun S

更新日期：2018-01-01 00:00:00

abstract：:Time-resolved singlet oxygen, O(2)(a(1)Delta(g)), phosphorescence experiments have been performed in single cells upon pulsed laser irradiation of a photosensitizer incorporated into the cell. Data recorded as a function of the partial pressure of ambient oxygen to which the cell is exposed reflect apparent values for...

journal_title：Photochemistry and photobiology

authors： Hatz S,Poulsen L,Ogilby PR

更新日期：2008-09-01 00:00:00

abstract：:Dark-grown leaves of maize (Zea mays), wheat (Triticum aestivum), wild-type pea (Pisum sativum) and its light-independent photomorphogenesis mutant (lip1) have different proportions of protochlorophyllide (Pchlide) forms as revealed by low-temperature fluorescence emission spectra. Four discrete spectral forms of Pchl...

journal_title：Photochemistry and photobiology

authors： Myśliwa-Kurdziel B,Amirjani MR,Strzałka K,Sundqvist C

更新日期：2003-08-01 00:00:00

abstract：:Sulfur-substituted nucleobases (a.k.a., thiobases) are among the world's leading prescriptions for chemotherapy and immunosuppression. Long-term treatment with azathioprine, 6-mercaptopurine and 6-thioguanine has been correlated with the photoinduced formation of carcinomas. Establishing an in-depth understanding of t...

journal_title：Photochemistry and photobiology

authors： Ashwood B,Pollum M,Crespo-Hernández CE

更新日期：2019-01-01 00:00:00

abstract：:UVB radiation contributes to both direct and indirect damage to the skin including the generation of free radicals and reactive oxygen species (ROS), inflammatory responses, immunosuppression and gene mutations, which can ultimately lead to photocarcinogenesis. A plant-derived flavonoid, baicalin, has been shown to ha...

journal_title：Photochemistry and photobiology

authors： Min W,Ahmad I,Chang ME,Burns EM,Qian Q,Yusuf N

更新日期：2015-11-01 00:00:00

abstract：:Pyrimidine dimers were measured in epidermal DNA of SKH:HR1 mice following exposure to solar-simulated UV radiation (SSUV, 290-400 nm) or to UVA (320-400 nm). Mice were exposed to SSUV or UVA after topical application (2 mg/cm2) of vehicle, a UVB absorber (5% 2-ethylhexyl p-methoxycinnamate [2-EHMC]), or a broad-spect...

journal_title：Photochemistry and photobiology

authors： Ley RD,Fourtanier A

更新日期：1997-06-01 00:00:00

abstract：:Catalases are oxidized by singlet oxygen giving rise to more acidic conformers detected in zymograms after electrophoresis in polyacrylamide gels. This shift in catalase mobility can be indicative of singlet oxygen production in vivo. Catalase from human cells, as from many organisms, is susceptible to in vitro modifi...

journal_title：Photochemistry and photobiology

authors： Lledías F,Hansberg W

更新日期：1999-12-01 00:00:00

abstract：:Cyclooxygenase (COX)-2 inhibitors are known to be used as chemopreventative agents against certain malignancies. Thus far, there has been very limited information on whether COX-2 inhibitors protect against chronic narrow-band UVB (NB-UVB)-induced immunosuppression. The present study investigated the effect of nonsele...

journal_title：Photochemistry and photobiology

authors： Wu Y,Tai CL,Wei H,He F,Wang Y,Zhao Y,Chen HD

更新日期：2008-03-01 00:00:00

abstract：:Betanin (betanidin 5-O-β-D-glucoside) is a water-soluble plant pigment used as a color additive in food, drugs and cosmetic products. Despite its sensitivity to light and heat, betanin maintains appreciable tinctorial strength in low acidic and neutral conditions, where the color of other plant pigments, such as antho...

journal_title：Photochemistry and photobiology

authors： Esteves LC,Pinheiro AC,Pioli RM,Penna TC,Baader WJ,Correra TC,Bastos EL

更新日期：2018-09-01 00:00:00

abstract：:We have investigated the factors that affect the virucidal activity of methylene blue (MB) photosensitization. The M13 bacteriophage was more rapidly inactivated at higher temperatures (6 degrees C < 24 degrees C < 38 degrees C). Rate constants for inactivation were 0.072, 0.139 and 0.260 (log10 inactivation)/ (J/cm2)...

journal_title：Photochemistry and photobiology

authors： Abe H,Wagner SJ,Kuwabara M,Kamo N,Ikebuchi K,Sekiguchi S

更新日期：1997-05-01 00:00:00