Revisiting the Mechanism of Hydrolysis of Betanin.

abstract：:A 24 h preculture of HT29-18 human colonic adenocarcinoma cells with the sterol synthesis inhibitor lovastatin at concentrations of 0.1-0.5 microM markedly increased the photocytotoxic effect of photofrin II delivered to cells by low density lipoproteins. Under the same conditions, LDL binding and photofrin II (PII) u...

journal_title：Photochemistry and photobiology

authors： Biade S,Mazière JC,Mora L,Santus R,Mazière C,Auclair M,Morlière P,Dubertret L

更新日期：1993-02-01 00:00:00

abstract：:Cyamemazine (CMZ) is a neuroleptic drug that mediates cutaneous phototoxicity in humans. Here, the photobehavior of CMZ has been examined within α1 -acid glycoproteins, β- and γ-cyclodextrins and SDS micelles. In all these microenvironments, CMZ emission was enhanced and blue-shifted, and its lifetime was longer. Irra...

journal_title：Photochemistry and photobiology

authors： Limones-Herrero D,Pérez-Ruiz R,Jiménez MC,Miranda MA

更新日期：2014-09-01 00:00:00

abstract：:The effect of charge on the cellular uptake, localization and phototoxicity of conjugates between chlorin(e6) (ce6) and poly-L-lysine was studied in vitro. These conjugates (average MW 35-55 kDa) were synthesized to have polycationic, polyanionic or neutral charges. Two human cell lines (A431 epidermoid carcinoma cell...

journal_title：Photochemistry and photobiology

authors： Soukos NS,Hamblin MR,Hasan T

更新日期：1997-04-01 00:00:00

abstract：:Topical photodynamic therapy is used for a variety of malignant and pre-malignant skin disorders, including Bowen's Disease and Superficial Basal Cell Carcinoma. A haem precursor, typically 5-aminolevulinic acid (ALA), acting as a prodrug, is absorbed and converted by the haem biosynthetic pathway to photoactive proto...

journal_title：Photochemistry and photobiology

authors： Donnelly RF,McCarron PA,Woolfson AD

更新日期：2005-07-01 00:00:00

abstract：:Syntheses for the new photosensitizers HOSiPcOSi(CH3)2(CH2)3N(CH1)1 or 3(CH3)2, Pc 34 and Pc 25, have been developed and the order of activity of these photosensitizers and the previously reported photosensitizer Pc 4, HOSiPcOSi(CH3)2(CH2)3N(CH3)2, in the dark and with broad-band red light toward Plasmodium falciparum...

journal_title：Photochemistry and photobiology

authors： Zhao XJ,Lustigman S,Li YS,Kenney ME,Ben-Hur E

更新日期：1997-08-01 00:00:00

abstract：:Angelica archangelia (AA), a traditional herb, has attracted attention as an agent with potential for use in the prevention of chronic skin diseases. This study examined the photoprotective effects of AA on the inhibition of matrix metalloproteinases (MMPs) and collagen degradation in UVB-irradiated normal human derma...

journal_title：Photochemistry and photobiology

authors： Sun Z,Hwang E,Park SY,Zhang M,Gao W,Lin P,Yi TH

更新日期：2016-07-01 00:00:00

abstract：:Skh:HR-1 hairless mice were irradiated chronically with sub-erythemal doses of UVB radiation, and a number of biochemical parameters in the skin were determined after 6, 12, 18, and 24 wk of exposure. The parameters measured were water, collagen, elastin, and glycosaminoglycan content; collagenase and elastase levels;...

journal_title：Photochemistry and photobiology

authors： Chatterjee R,Benzinger MJ,Ritter JL,Bissett DL

更新日期：1990-01-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Laser flash photolysis was used to determine the kinetics of electron transfer between membrane-bound triplet chlorophyll (3C), cytochrome c (cyt c) located in the external water phase, and vesicle-reconstituted cytochrome c oxidase (CCO). 2,5-Di-t-butyl benzoquinone (2,5 TBQ) was used as an electron transfer mediator...

journal_title：Photochemistry and photobiology

authors： Chamupathi VG,Moezzi DM,Tollin G

更新日期：1990-10-01 00:00:00

abstract：:Proteases like urokinase-type plasminogen activator (uPA) play an important role in tumor invasion. Cells derived from ultraviolet radiation (UVR)-induced corneal sarcomas of Monodelphis domestica produce relatively high levels of uPA compared to the untransformed keratocytes suggesting a mechanism for their invasiven...

journal_title：Photochemistry and photobiology

authors： Green WB,McGuire PG,Miska KB,Kusewitt DF

更新日期：2001-03-01 00:00:00

abstract：:The response of normal brain to photodynamic therapy (PDT) was investigated in 62 Fisher rats. The animals were injected i.p. with Photofrin II (12.5 mg/kg). Forty-eight hours following injection, an area of dura 5 mm in diameter over the frontal cortex was photoactivated with red light (632 +/- 2 nm) at 100 mW cm-2, ...

journal_title：Photochemistry and photobiology

authors： Dereski MO,Chopp M,Garcia JH,Hetzel FW

更新日期：1991-07-01 00:00:00

abstract：:Channel and pump rhodopsins use energy from light absorbed by a covalently bound retinal chromophore to transport ions across membranes of microbial cells. Ion transfer steps, including proton transfer, can couple to changes in protein conformational dynamics and water positions. Although general principles of how mic...

journal_title：Photochemistry and photobiology

authors： Bondar AN,Smith JC

更新日期：2017-11-01 00:00:00

abstract：:Phototherapy with broadband UVB is an effective treatment for inflammatory dermatoses. A newly developed fluorescent UVB lamp (Philips TL01) that emits a narrowband UVB around 311 nm was shown to be superior for the phototherapy of psoriasis. In order to contribute to the knowledge about the carcinogenic potential of ...

journal_title：Photochemistry and photobiology

authors： Tzung TY,Rünger TM

更新日期：1998-06-01 00:00:00

abstract：:The potential for electron transfer quenching of rose bengal triplet (3RB2-) to compete with energy transfer quenching by oxygen was evaluated. Rate constants for oxidative and reductive quenching were measured in buffered aqueous solution, acetonitrile and in small unilamellar liposomes using laser flash photolysis. ...

journal_title：Photochemistry and photobiology

authors： Lambert CR,Kochevar IE

更新日期：1997-07-01 00:00:00

abstract：:Ultraviolet A radiation participates in cytotoxicity and carcinogenesis of the skin by a mechanism involving the generation of reactive oxygen species. Endogenous antiradical defense systems utilize metalloenzymes including Se-dependent glutathione peroxidase and Cu and Zn superoxide dismutase. The aim of the present ...

journal_title：Photochemistry and photobiology

authors： Leccia MT,Richard MJ,Beani JC,Faure H,Monjo AM,Cadet J,Amblard P,Favier A

更新日期：1993-10-01 00:00:00

abstract：:The photodynamic therapy (PDT) activity of the bis(dimethylthexylsiloxy)silicon 2,3-naphthalocyanine (SiNc 8) was evaluated against the EMT-6 tumor implanted intradermally in BALB/c mice. The SiNc 8 was formulated in aqueous emulsions based on Cremophor EL or Solutol HS 15. The formulation was shown to affect plasma c...

journal_title：Photochemistry and photobiology

authors： Brasseur N,Ouellet R,Lewis K,Potter WR,van Lier JE

更新日期：1995-12-01 00:00:00

abstract：:Confocal laser microspectrofluorometric measurements on human T47D mammary tumor cells have been performed to assess the intracellular distribution of hypericin within the various cell compartments: cytoplasmic membrane, cytoplasm and nucleus. Confocal fluorescence measurements obtained from microvolumes (approximatel...

journal_title：Photochemistry and photobiology

authors： Miskovsky P,Sureau F,Chinsky L,Turpin PY

更新日期：1995-09-01 00:00:00

abstract：:Cationic polythiophenes have been shown to be potent antimicrobial compounds due to their ability to absorb visible light and sensitize the production of reactive oxygen species (ROS) as well as their ability to selectively associate with and damage negatively charged cell envelopes. This study demonstrates the abilit...

journal_title：Photochemistry and photobiology

authors： Brown DM,Yang J,Strach EW,Khalil MI,Whitten DG

更新日期：2018-11-01 00:00:00

abstract：:Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

journal_title：Photochemistry and photobiology

authors： Das A,Lao EA,Gudmundsdottir AD

更新日期：2016-05-01 00:00:00

abstract：:Nuclear factor-kappa B (NF-kappaB) plays an important role in UV-induced skin tumorigenesis. Activation of NF-kappaB by UV-irradiation is composed of two phases. The early phase culminates with maximal levels of DNA binding ability at 4 h postirradiation and is dependent on translational inhibition. The late-phase act...

journal_title：Photochemistry and photobiology

authors： László CF,Wu S

更新日期：2008-11-01 00:00:00

abstract：:Fibrous proteins discolor on exposure to the UV component of sunlight. This effect is exacerbated in the presence of fluorescent whitening agents (FWAs), which are often applied to textiles to improve product brightness. Tryptophan photoproducts have been identified as significant contributors to protein photoyellowin...

journal_title：Photochemistry and photobiology

authors： Dyer JM,Clerens S,Cornellison CD,Murphy CJ,Maurdev G,Millington KR

更新日期：2009-11-01 00:00:00

abstract：:There are controversial reports in the literature concerning the reactivity of singlet oxygen ((1)O(2)) with the redox probe 2',7'-dichlorodihydrofluorescein (DCFH). By carefully preparing solutions in which (1)O(2) is quantitatively generated in the presence of DCFH, we were able to show that the formation rate of th...

journal_title：Photochemistry and photobiology

authors： Daghastanli NA,Itri R,Baptista MS

更新日期：2008-09-01 00:00:00

abstract：:Photodynamic therapy (PDT) of solid tumors elicits a strong, acute inflammatory response characterized by a rapid and massive infiltration of activated neutrophils into the tumor. The present study investigated the impact of PDT on the systemic and local (treatment site) kinetics of neutrophil trafficking and activity...

journal_title：Photochemistry and photobiology

authors： Cecic I,Parkins CS,Korbelik M

更新日期：2001-11-01 00:00:00

abstract：:Dermatophytes are fungi that can cause infections (known as tinea) of the skin, hair and nails because of their ability to use keratin. Superficial mycoses are probably the most prevalent of infectious diseases worldwide. One of the most distinct limitations of the current therapeutic options is the recurrence of the ...

journal_title：Photochemistry and photobiology

authors： Smijs TG,Schuitmaker HJ

更新日期：2003-05-01 00:00:00

abstract：:Cyanines are emerging as useful agents for photoreleasing biological compounds because of their capability of utilizing near-infrared (NIR) light. Another benefit is their ability to self-sensitize to produce singlet oxygen for the release of aryl amines, a process that has not been as feasible in the past. Here, we h...

journal_title：Photochemistry and photobiology

authors： Mathew JP,Greer A

更新日期：2019-09-01 00:00:00

abstract：:Action spectroscopy has a long history and is of central importance to photobiological studies. Action spectra were among the first assays to point to chlorophyll as the molecule most responsible for plant growth and to DNA as the genetic material. It is useful to construct action spectra early in the investigation of...

journal_title：Photochemistry and photobiology

authors： Coohill TP

更新日期：1991-11-01 00:00:00

abstract：:Elemental sulfur is a low-cost and abundant substance as one of the largest by-products of the oil industry which was widely used in many industrial activities. Cyclo-octasulfur (S8 ) is one of the sulfur allotropes that is a very stable substance in standard conditions. In this study, we report a low-cost and fast me...

journal_title：Photochemistry and photobiology

authors： Peyman VA,Azizian S

更新日期：2020-11-01 00:00:00

abstract：:Chronic exposure of the gray, short-tailed oppossum, Monodelphis domestica to ultraviolet radiation (UVR) induces mesenchymal tumors of the cornea. High molecular weight DNA samples from 6 UVR-induced corneal tumors were assayed for their ability to transform NIH 3T3 cells to tumorigenicity. NIH 3T3 cells transfected ...

journal_title：Photochemistry and photobiology

authors： Sabourin CL,Freeman AG,Kusewitt DF,Ley RD

更新日期：1992-03-01 00:00:00

abstract：:The temperature dependence of the uptake phase of 5-aminolevulinic acid (ALA) and the following production phase of protoporphyrin IX (PpIX) in normal mouse skin was investigated. A cream containing 20% ALA was topically applied on the skin for 10 min. The amount of ALA-induced PpIX was evaluated by measuring the fluo...

journal_title：Photochemistry and photobiology

authors： Juzenas P,Sørensen R,Iani V,Moan J

更新日期：1999-04-01 00:00:00

abstract：:The dependence of autofluorescence properties on the metabolic and functional engagement and on the transformation condition was studied on single cells. Normal Galliera rat fibroblasts at low subculture passage (cell strain), at high subculture passage (stabilized cell line), and transformed cell line derived from a ...

journal_title：Photochemistry and photobiology

authors： Croce AC,Spano A,Locatelli D,Barni S,Sciola L,Bottiroli G

更新日期：1999-03-01 00:00:00